Sergia Velho

Summary

Affiliation: Institute of Molecular Pathology and Immunology
Country: Portugal

Publications

  1. pmc Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation
    Sergia Velho
    Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Rua Dr, Roberto Frias, 4200 465 Porto, Portugal
    BMC Cancer 14:182. 2014
  2. pmc BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
    Sergia Velho
    Institute of Molecular Pathology and Immunology, University of Porto, Portugal
    BMC Cancer 8:255. 2008
  3. ncbi request reprint A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation
    Ana Preto
    Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    Virchows Arch 450:619-26. 2007
  4. ncbi request reprint Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
    Carla Oliveira
    Institute of Molecular Pathology and Immunology, The University of Porto, IPATIMUP, 4200 465 Porto, Portugal
    Hum Mol Genet 13:2303-11. 2004

Detail Information

Publications4

  1. pmc Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation
    Sergia Velho
    Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Rua Dr, Roberto Frias, 4200 465 Porto, Portugal
    BMC Cancer 14:182. 2014
    ..Nevertheless, the molecular mechanism underlying the oncogenic activity of P252H mutant remained elusive...
  2. pmc BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?
    Sergia Velho
    Institute of Molecular Pathology and Immunology, University of Porto, Portugal
    BMC Cancer 8:255. 2008
    ..In the series of polyps CIMP, MLH1 methylation and MSI were also studied...
  3. ncbi request reprint A subset of colorectal carcinomas express c-KIT protein independently of BRAF and/or KRAS activation
    Ana Preto
    Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    Virchows Arch 450:619-26. 2007
    ..STI571/Gleevec increases apoptosis in CRC cell lines independently of its genetic profile, suggesting that STI571/Gleevec is likely to be an alternative drug for the clinical trials of CRC...
  4. ncbi request reprint Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
    Carla Oliveira
    Institute of Molecular Pathology and Immunology, The University of Porto, IPATIMUP, 4200 465 Porto, Portugal
    Hum Mol Genet 13:2303-11. 2004
    ....