Detail Information
Publications
The mTOR Signalling Pathway in Human CancerHelena Pópulo
Institute of Molecular Pathology and Immunology of University of Porto IPATIMUP, University of Porto, 4200 465, Porto, Portugal E Mails H P J M L
Int J Mol Sci 13:1886-918. 2012..In this review, we aim to survey relevant research, the molecular mechanisms of signalling, including upstream activation and downstream effectors, and the role of mTOR in cancer, mainly in melanoma...
Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomasHelena Pópulo
Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal
Br J Ophthalmol 95:715-9. 2011..To study the GNAQ mutational status in a series of uveal melanomas and evaluate possible associations with mitogen-activated protein kinase (MAPK) pathway protein expression and tumour proliferation markers...
