- The mTOR Signalling Pathway in Human CancerHelena Pópulo
Institute of Molecular Pathology and Immunology of University of Porto IPATIMUP, University of Porto, 4200 465, Porto, Portugal E Mails H P J M L
Int J Mol Sci 13:1886-918. 2012..In this review, we aim to survey relevant research, the molecular mechanisms of signalling, including upstream activation and downstream effectors, and the role of mTOR in cancer, mainly in melanoma...
- Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomasHelena Pópulo
Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal
Br J Ophthalmol 95:715-9. 2011..To study the GNAQ mutational status in a series of uveal melanomas and evaluate possible associations with mitogen-activated protein kinase (MAPK) pathway protein expression and tumour proliferation markers...