Isabel Pereira Castro

Summary

Affiliation: Institute of Molecular Pathology and Immunology
Country: Portugal

Publications

  1. ncbi request reprint ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer
    Ginesa Garcia-Rostan
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    J Clin Oncol 21:3226-35. 2003
  2. ncbi request reprint Mutation of the PIK3CA gene in anaplastic thyroid cancer
    Ginesa Garcia-Rostan
    Institute of Molecular Pathology and Immunology of Porto University, Porto, Portugal
    Cancer Res 65:10199-207. 2005
  3. ncbi request reprint Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines
    Ana Margarida Meireles
    Institute of Pathology and Molecular Immunology, University of Porto IPATIMUP, Porto, Portugal
    Thyroid 17:707-15. 2007
  4. ncbi request reprint High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations
    Jorge Lima
    Institute of Molecular Pathology and Immunology of University of Porto, University of Porto, 4200 465 Porto, Portugal
    J Clin Endocrinol Metab 92:4853-64. 2007

Collaborators

Detail Information

Publications4

  1. ncbi request reprint ras mutations are associated with aggressive tumor phenotypes and poor prognosis in thyroid cancer
    Ginesa Garcia-Rostan
    Department of Pathology, Yale University School of Medicine, New Haven, CT, USA
    J Clin Oncol 21:3226-35. 2003
    ..ras oncogenic activation has long been demonstrated in thyroid carcinomas of follicular cell derivation, but no consistent relationship has been shown between mutations and clinicopathologic features...
  2. ncbi request reprint Mutation of the PIK3CA gene in anaplastic thyroid cancer
    Ginesa Garcia-Rostan
    Institute of Molecular Pathology and Immunology of Porto University, Porto, Portugal
    Cancer Res 65:10199-207. 2005
    ..These findings indicate that mutant PIK3CA is likely to function as an oncogene among ATC and less frequently well-differentiated thyroid carcinomas. The data also argue for a role of PIK3CA targeting in the treatment of ATC patients...
  3. ncbi request reprint Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines
    Ana Margarida Meireles
    Institute of Pathology and Molecular Immunology, University of Porto IPATIMUP, Porto, Portugal
    Thyroid 17:707-15. 2007
    ..Our aim was to characterize the molecular and genotypic profile of eight thyroid carcinoma-derived cell lines-TPC1, FB2, B-CPAP, K1, XTC-1, C643, 8505C, and Hth74-in order to use them as in vitro models of thyroid carcinogenesis...
  4. ncbi request reprint High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations
    Jorge Lima
    Institute of Molecular Pathology and Immunology of University of Porto, University of Porto, 4200 465 Porto, Portugal
    J Clin Endocrinol Metab 92:4853-64. 2007
    ....