Jose L Costa
Affiliation: Institute of Molecular Pathology and Immunology
- Vitamin D and the mammary gland: a review on its role in normal development and breast cancerNair Lopes
IPATIMUP Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias, S N, 4200 465, Porto, Portugal
Breast Cancer Res 14:211. 2012..Accordingly, we review data on the influence of vitamin D in the development of normal breast and the expression of vitamin D-related proteins (VDR, CYP27B1 and CYP24A21) in benign mammary lesions and ductal carcinomas in situ...
- Nonoptical massive parallel DNA sequencing of BRCA1 and BRCA2 genes in a diagnostic settingJosé Luis Costa
Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
Hum Mutat 34:629-35. 2013....
- High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancerSuet F Chin
Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
Genome Biol 8:R215. 2007..To date, most genome-wide array comparative genomic hybridization studies have used tumor panels of relatively large tumor size and high Nottingham Prognostic Index (NPI) that are not as representative of breast cancer demographics...
- Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-downJose L Costa
Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
BMC Genomics 10:499. 2009..In contrast, the molecular mechanism of 1,25D for the regulation of calcium homeostasis has principally been resolved, demonstrating a pivotal role for the vitamin D receptor (VDR)...
- Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesionsNair Lopes
Institute of Molecular Pathology and Immunology of the University of Porto, Porto 4200 465, Portugal
BMC Cancer 10:483. 2010..We aimed to study the expression of these three proteins by immunohistochemistry in a series of breast lesions...