Jose L Costa

Summary

Affiliation: Institute of Molecular Pathology and Immunology
Country: Portugal

Publications

  1. pmc Vitamin D and the mammary gland: a review on its role in normal development and breast cancer
    Nair Lopes
    IPATIMUP Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias, S N, 4200 465, Porto, Portugal
    Breast Cancer Res 14:211. 2012
  2. doi Nonoptical massive parallel DNA sequencing of BRCA1 and BRCA2 genes in a diagnostic setting
    José Luis Costa
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
    Hum Mutat 34:629-35. 2013
  3. pmc High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
    Suet F Chin
    Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Genome Biol 8:R215. 2007
  4. pmc Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down
    Jose L Costa
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    BMC Genomics 10:499. 2009
  5. pmc Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions
    Nair Lopes
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto 4200 465, Portugal
    BMC Cancer 10:483. 2010

Collaborators

Detail Information

Publications5

  1. pmc Vitamin D and the mammary gland: a review on its role in normal development and breast cancer
    Nair Lopes
    IPATIMUP Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias, S N, 4200 465, Porto, Portugal
    Breast Cancer Res 14:211. 2012
    ..Accordingly, we review data on the influence of vitamin D in the development of normal breast and the expression of vitamin D-related proteins (VDR, CYP27B1 and CYP24A21) in benign mammary lesions and ductal carcinomas in situ...
  2. doi Nonoptical massive parallel DNA sequencing of BRCA1 and BRCA2 genes in a diagnostic setting
    José Luis Costa
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
    Hum Mutat 34:629-35. 2013
    ....
  3. pmc High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
    Suet F Chin
    Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK
    Genome Biol 8:R215. 2007
    ..To date, most genome-wide array comparative genomic hybridization studies have used tumor panels of relatively large tumor size and high Nottingham Prognostic Index (NPI) that are not as representative of breast cancer demographics...
  4. pmc Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down
    Jose L Costa
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    BMC Genomics 10:499. 2009
    ..In contrast, the molecular mechanism of 1,25D for the regulation of calcium homeostasis has principally been resolved, demonstrating a pivotal role for the vitamin D receptor (VDR)...
  5. pmc Alterations in Vitamin D signalling and metabolic pathways in breast cancer progression: a study of VDR, CYP27B1 and CYP24A1 expression in benign and malignant breast lesions
    Nair Lopes
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto 4200 465, Portugal
    BMC Cancer 10:483. 2010
    ..We aimed to study the expression of these three proteins by immunohistochemistry in a series of breast lesions...