Research Topics
| F FixeSummaryCountry: Portugal Publications
| Collaborators |
Detail Information
Publications
Immobilization and hybridization by single sub-millisecond electric field pulses, for pixel-addressed DNA microarraysF Fixe
INESC Microsistemas e Nanotecnologias INESC MN, Rua Alves Redol, 9, 1000 029 Lisbon, Portugal
Biosens Bioelectron 19:1591-7. 2004..This reduces steric barriers and speeds the immobilization and hybridization reactions. These results open the way for pixel-addressed microarrays driven by silicon microelectronics circuits...
An on-chip thin film photodetector for the quantification of DNA probes and targets in microarraysF Fixe
INESC Microsistemas e Nanotecnologias INESC MN, Rua Alves Redol, 9, 1000 029 Lisboa, Portugal
Nucleic Acids Res 32:e70. 2004..7 +/- 1.5 pmol/cm2 was measured for the complementary DNA hybridized to the bound DNA. The detection concept explored can enable on-chip electronic data acquisition, improving both the speed and the reliability of DNA microarrays...
One-step immobilization of aminated and thiolated DNA onto poly(methylmethacrylate) (PMMA) substratesF Fixe
INESC, Microsistemas e Nanotecnologias (INESC-MN, Rua Alves Redol, 9, 1000-029 Lisboa, Portugal
Lab Chip 4:191-5. 2004..Furthermore, the chemical bond between the immobilized DNA and the PMMA could endure repeated heat cycling with only 50% probe loss after 20 cycles, indicating that the chemistry could be used in integrated PCR/microarray devices...
Single base mismatch detection by microsecond voltage pulsesF Fixe
INESC-Microsistemas and Nanotecnologias, INESC MN, Rua Alves Redol, 9, 1000-029 Lisboa, Portugal
Biosens Bioelectron 21:888-93. 2005....
Functionalization of poly(methyl methacrylate) (PMMA) as a substrate for DNA microarraysF Fixe
INESC, Microsistemas e Nanotecnologias (INESC-MN, Rua Alves Redol, 9, 1000-029 Lisboa, Portugal
Nucleic Acids Res 32:e9. 2004....
