Affiliation: Faculty of Medicine
- Reactive oxygen species downregulate glucose transport system in retinal endothelial cellsRosa Fernandes
Center of Opththalmology and Vision Sciences, Institute for Biomedical Research in Light and Image, Faculty of Medicine, University of Coimbra, Portugal
Am J Physiol Cell Physiol 300:C927-36. 2011..Thus subcellular redistribution of GLUT1 under conditions of oxidative stress is likely to contribute to the disruption of glucose homeostasis in diabetes...
- Oxidative stress upregulates ubiquitin proteasome pathway in retinal endothelial cellsRosa Fernandes
Center of Ophthalmology, Biomedical Institute for Research in Light and Image IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Mol Vis 12:1526-35. 2006..To establish whether oxidative stress in retinal endothelial cells upregulates the ubiquitin proteasome pathway (UPP) leading to increased protein degradation in diabetes...
- Eps15 interacts with ubiquitinated Cx43 and mediates its internalizationHenrique Girao
Centre of Ophthalmology and Visual Sciences, Biomedical Institute for Research in Light and Image IBILI, Faculty of Medicine, University of Coimbra, Azinhaga de Sta Comba 3000 354 Coimbra, Portugal
Exp Cell Res 315:3587-97. 2009..This provides the basis for future studies aiming at identifying the molecular players and mechanisms involved in Cx43 internalization and degradation...