J Calado

Summary

Affiliation: Faculty of Medical Sciences
Country: Portugal

Publications

  1. ncbi Effect of kidney disease on glucose handling (including genetic defects)
    Joaquim Calado
    1 Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Lisbon, Portugal 2 Department of Nephrology, Curry Cabral Hospital, Lisbon, Portugal
    Kidney Int 79:S7-S13. 2011
  2. ncbi Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria
    Joaquim Calado
    Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Rua da Junqueira 96, 1349 008 Lisbon, Portugal
    Hum Genet 114:314-6. 2004
  3. ncbi Gene Symbol: SLC55A2. Disease: familial renal glucosuria
    J Calado
    Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal
    Hum Genet 115:170. 2004
  4. ncbi A novel heterozygous missense mutation in the UMOD gene responsible for Familial Juvenile Hyperuricemic Nephropathy
    Joaquim Calado
    Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Lisbon, Portugal
    BMC Med Genet 6:5. 2005
  5. ncbi Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting
    J Calado
    Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Rua da Junquiera no 96, 1349 008 Lisbon, Portugal
    Kidney Int 69:852-5. 2006
  6. ncbi Twenty-one additional cases of familial renal glucosuria: absence of genetic heterogeneity, high prevalence of private mutations and further evidence of volume depletion
    Joaquim Calado
    Departamento de Genética da Faculdade de Ciências Médicas, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal
    Nephrol Dial Transplant 23:3874-9. 2008
  7. ncbi Dapagliflozin, an oral sodium glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus
    Joaquim Calado
    New University of Lisbon, Department of Genetics, Faculty of Medical Sciences, Rua da Junqueira no 96, Lisbon, 1349 008, Portugal
    IDrugs 12:785-98. 2009
  8. ncbi Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target
    Rene Santer
    Department of Genetics, Faculty of Medical Sciences, Institute of Hygiene and Tropical Medicine, Universidade Nova de Lisboa, Rua da Junqueira no 96, 1349 008, Lisbon, Portugal
    Clin J Am Soc Nephrol 5:133-41. 2010
  9. ncbi Unusual adult-onset manifestation of an attenuated Bartter's syndrome type IV renal phenotype caused by a mutation in BSND
    Sandra Brum
    Nephrol Dial Transplant 22:288-9. 2007

Detail Information

Publications9

  1. ncbi Effect of kidney disease on glucose handling (including genetic defects)
    Joaquim Calado
    1 Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Lisbon, Portugal 2 Department of Nephrology, Curry Cabral Hospital, Lisbon, Portugal
    Kidney Int 79:S7-S13. 2011
    ..In this paper we focus on FRG and describe other inherited and acquired clinical conditions associated with glucosuria. In addition, a brief review on the regulation of renal glucose transport in diabetes is provided...
  2. ncbi Novel compound heterozygous mutations in SLC5A2 are responsible for autosomal recessive renal glucosuria
    Joaquim Calado
    Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Rua da Junqueira 96, 1349 008 Lisbon, Portugal
    Hum Genet 114:314-6. 2004
    ..N654S mutation involving a highly conserved residue. These findings confirm that mutations in the SLC5A2 gene are responsible for recessive renal glucosuria...
  3. ncbi Gene Symbol: SLC55A2. Disease: familial renal glucosuria
    J Calado
    Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal
    Hum Genet 115:170. 2004
  4. ncbi A novel heterozygous missense mutation in the UMOD gene responsible for Familial Juvenile Hyperuricemic Nephropathy
    Joaquim Calado
    Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Lisbon, Portugal
    BMC Med Genet 6:5. 2005
    ..Mutations in the uromodulin coding UMOD gene have been found responsible for the disease in some families...
  5. ncbi Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting
    J Calado
    Department of Genetics, Faculty of Medical Sciences, New University of Lisbon, Rua da Junquiera no 96, 1349 008 Lisbon, Portugal
    Kidney Int 69:852-5. 2006
    ..Definite proof of renin-angiotensin aldosterone system activation in FGR should rely on evaluation of additional patients with massive glucosuria...
  6. ncbi Twenty-one additional cases of familial renal glucosuria: absence of genetic heterogeneity, high prevalence of private mutations and further evidence of volume depletion
    Joaquim Calado
    Departamento de Genética da Faculdade de Ciências Médicas, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal
    Nephrol Dial Transplant 23:3874-9. 2008
    ..We have now extended this analysis to another 21 consecutive cases from 17 pedigrees, including 11 cases with severe glucose excretion...
  7. ncbi Dapagliflozin, an oral sodium glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus
    Joaquim Calado
    New University of Lisbon, Department of Genetics, Faculty of Medical Sciences, Rua da Junqueira no 96, Lisbon, 1349 008, Portugal
    IDrugs 12:785-98. 2009
    ..The major adverse effect associated with dapagliflozin appears to be an increased occurrence of mycotic genital infections...
  8. ncbi Familial renal glucosuria and SGLT2: from a mendelian trait to a therapeutic target
    Rene Santer
    Department of Genetics, Faculty of Medical Sciences, Institute of Hygiene and Tropical Medicine, Universidade Nova de Lisboa, Rua da Junqueira no 96, 1349 008, Lisbon, Portugal
    Clin J Am Soc Nephrol 5:133-41. 2010
    ..This review provides an overview of renal glucose transport physiology, FRG and its clinical course, and the potential of SGLT2 inhibition as a therapeutic target in type 2 diabetes...
  9. ncbi Unusual adult-onset manifestation of an attenuated Bartter's syndrome type IV renal phenotype caused by a mutation in BSND
    Sandra Brum
    Nephrol Dial Transplant 22:288-9. 2007