José Braga

Summary

Affiliation: Faculdade de Medicina
Country: Portugal

Publications

  1. pmc A reaction-diffusion model to study RNA motion by quantitative fluorescence recovery after photobleaching
    José Braga
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
    Biophys J 92:2694-703. 2007
  2. pmc Intracellular macromolecular mobility measured by fluorescence recovery after photobleaching with confocal laser scanning microscopes
    José Braga
    Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, 1649 028 Lisbon, Portugal
    Mol Biol Cell 15:4749-60. 2004
  3. pmc The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive
    Alexandre Calapez
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649 028 Lisboa, Portugal
    J Cell Biol 159:795-805. 2002
  4. pmc Inactivation of cleavage factor I components Rna14p and Rna15p induces sequestration of small nucleolar ribonucleoproteins at discrete sites in the nucleus
    Tiago Carneiro
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649 028 Lisboa, Portugal
    Mol Biol Cell 19:1499-508. 2008
  5. ncbi request reprint Photobleaching microscopy reveals the dynamics of mRNA-binding proteins inside live cell nuclei
    José Braga
    Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, 1649 028, Lisbon, Portugal
    Prog Mol Subcell Biol 35:119-34. 2004
  6. doi request reprint Frontiers in fluorescence microscopy
    José Rino
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
    Int J Dev Biol 53:1569-79. 2009
  7. pmc A stochastic view of spliceosome assembly and recycling in the nucleus
    José Rino
    Instituto de Medicina Molecular, Universidade de Lisboa, Lisbon, Portugal
    PLoS Comput Biol 3:2019-31. 2007
  8. pmc Dynamic transitions in RNA polymerase II density profiles during transcription termination
    Ana Rita Grosso
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649 028 Lisboa, Portugal
    Genome Res 22:1447-56. 2012
  9. pmc In vivo aggregation properties of the nuclear poly(A)-binding protein PABPN1
    João Paulo Tavanez
    Institute of Molecular Medicine, Faculty of Medicine, Av Prof Egas Moniz, 1649 028 Lisboa, Portugal
    RNA 11:752-62. 2005
  10. pmc Depletion of the yeast nuclear exosome subunit Rrp6 results in accumulation of polyadenylated RNAs in a discrete domain within the nucleolus
    Tiago Carneiro
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av Prof Egas Moniz, 1649 028 Lisbon, Portugal
    Mol Cell Biol 27:4157-65. 2007

Collaborators

Detail Information

Publications11

  1. pmc A reaction-diffusion model to study RNA motion by quantitative fluorescence recovery after photobleaching
    José Braga
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
    Biophys J 92:2694-703. 2007
    ..The results show that interpreting FRAP data in light of the new model reconciles the discrepant mRNA diffusion-rate values previously reported...
  2. pmc Intracellular macromolecular mobility measured by fluorescence recovery after photobleaching with confocal laser scanning microscopes
    José Braga
    Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, 1649 028 Lisbon, Portugal
    Mol Biol Cell 15:4749-60. 2004
    ..This suggests that spatial constraints to diffusion of dextrans inside the nucleus are insensitive to temperature...
  3. pmc The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive
    Alexandre Calapez
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649 028 Lisboa, Portugal
    J Cell Biol 159:795-805. 2002
    ..Taken together, the data suggest that the mobility of mRNPs in the living cell nucleus involves a combination of passive diffusion and ATP-dependent processes...
  4. pmc Inactivation of cleavage factor I components Rna14p and Rna15p induces sequestration of small nucleolar ribonucleoproteins at discrete sites in the nucleus
    Tiago Carneiro
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649 028 Lisboa, Portugal
    Mol Biol Cell 19:1499-508. 2008
    ..We propose that the foci detected after CFIA inactivation correspond to quality control centers in the nucleoplasm...
  5. ncbi request reprint Photobleaching microscopy reveals the dynamics of mRNA-binding proteins inside live cell nuclei
    José Braga
    Institute of Molecular Medicine, Faculty of Medicine, University of Lisbon, 1649 028, Lisbon, Portugal
    Prog Mol Subcell Biol 35:119-34. 2004
  6. doi request reprint Frontiers in fluorescence microscopy
    José Rino
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
    Int J Dev Biol 53:1569-79. 2009
    ..It all changed abruptly during the last two decades when the rapid development of novel imaging techniques revolutionized the way scientists look at the structures of life alive...
  7. pmc A stochastic view of spliceosome assembly and recycling in the nucleus
    José Rino
    Instituto de Medicina Molecular, Universidade de Lisboa, Lisbon, Portugal
    PLoS Comput Biol 3:2019-31. 2007
    ..Rather, the results suggest that splicing proteins are constantly diffusing throughout the entire nucleus and collide randomly and transiently with pre-mRNAs...
  8. pmc Dynamic transitions in RNA polymerase II density profiles during transcription termination
    Ana Rita Grosso
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649 028 Lisboa, Portugal
    Genome Res 22:1447-56. 2012
    ..Taken together, our results provide novel insight to transcription termination, a fundamental process that remains one of the least understood stages of the transcription cycle...
  9. pmc In vivo aggregation properties of the nuclear poly(A)-binding protein PABPN1
    João Paulo Tavanez
    Institute of Molecular Medicine, Faculty of Medicine, Av Prof Egas Moniz, 1649 028 Lisboa, Portugal
    RNA 11:752-62. 2005
    ..These findings have important implications for the interpretation of OPMD model systems based on exogenous expression of PABPN1...
  10. pmc Depletion of the yeast nuclear exosome subunit Rrp6 results in accumulation of polyadenylated RNAs in a discrete domain within the nucleolus
    Tiago Carneiro
    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Av Prof Egas Moniz, 1649 028 Lisbon, Portugal
    Mol Cell Biol 27:4157-65. 2007
    ..The accumulation of polyadenylated snoRNAs in a discrete nucleolar domain may promote their recognition as substrates for the exosome...
  11. pmc Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis
    Marta Agostinho
    Institute of Histology, Faculty of Medicine, University of Lisbon, 1649 028 Lisbon, Portugal
    Mol Biol Cell 15:2388-400. 2004
    ..Together, our data implicate several previously unsuspected activities in the partitioning of the enzyme between sites of activity and putative depots...