Carla C C R de Carvalho

Summary

Country: Portugal

Publications

  1. doi request reprint Enzymatic and whole cell catalysis: finding new strategies for old processes
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Biotechnol Adv 29:75-83. 2011
  2. pmc Lipids of prokaryotic origin at the base of marine food webs
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Tecnico, Technical University of Lisbon, Av Rovisco Pais, Lisbon 1049 001, Portugal
    Mar Drugs 10:2698-2714. 2012
  3. doi request reprint Tumour metastasis as an adaptation of tumour cells to fulfil their phosphorus requirements
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Med Hypotheses 78:664-7. 2012
  4. doi request reprint Adaptation of Rhodococcus erythropolis cells for growth and bioremediation under extreme conditions
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Res Microbiol 163:125-36. 2012
  5. ncbi request reprint Biofilms: new ideas for an old problem
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Recent Pat Biotechnol 6:13-22. 2012
  6. ncbi request reprint Recent achievements on siderophore production and application
    Carla C C R de Carvalho
    Department of Bioengineering, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Portugal
    Recent Pat Biotechnol 5:183-98. 2011
  7. pmc Production of metabolites as bacterial responses to the marine environment
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisbon, Portugal
    Mar Drugs 8:705-27. 2010
  8. ncbi request reprint Biofilms: recent developments on an old battle
    Carla C C R de Carvalho
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Recent Pat Biotechnol 1:49-57. 2007
  9. ncbi request reprint Adaptation of Rhodococcus erythropolis cells to high concentrations of toluene
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Appl Microbiol Biotechnol 76:1423-30. 2007
  10. ncbi request reprint Preventing biofilm formation: promoting cell separation with terpenes
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisboa, Portugal
    FEMS Microbiol Ecol 61:406-13. 2007

Collaborators

Detail Information

Publications26

  1. doi request reprint Enzymatic and whole cell catalysis: finding new strategies for old processes
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Biotechnol Adv 29:75-83. 2011
    ..Bacteria able to thrive under the most extreme conditions have also provided new and extraordinary catalytic processes. In this review, the new tools available for the improvement of biocatalysts are presented and discussed...
  2. pmc Lipids of prokaryotic origin at the base of marine food webs
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Department of Bioengineering, Instituto Superior Tecnico, Technical University of Lisbon, Av Rovisco Pais, Lisbon 1049 001, Portugal
    Mar Drugs 10:2698-2714. 2012
    ..The present work aims to provide a comprehensive review on lipid production in bacteria and archaea and to discuss how their lipids, of both heterotrophic and chemoautotrophic origin, contribute to marine food webs...
  3. doi request reprint Tumour metastasis as an adaptation of tumour cells to fulfil their phosphorus requirements
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Med Hypotheses 78:664-7. 2012
    ..Considering that the cells most P-deprived should be located in the inner parts of the tumour we propose that changes in the membrane of these cells favour the detachment of the more peripheral cells...
  4. doi request reprint Adaptation of Rhodococcus erythropolis cells for growth and bioremediation under extreme conditions
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Res Microbiol 163:125-36. 2012
    ..The adapted R. erythropolis cells were able to degrade C6-C16 n-alkanes and alcohols under the previously considered extreme conditions for this bacterium...
  5. ncbi request reprint Biofilms: new ideas for an old problem
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Recent Pat Biotechnol 6:13-22. 2012
    ..Biofilm formation is related to the pathogenicity of some bacterial strains and cells in biofilms are usually resistant to antimicrobials agents, which increases the interest in new and sound methods for their prevention and destruction...
  6. ncbi request reprint Recent achievements on siderophore production and application
    Carla C C R de Carvalho
    Department of Bioengineering, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Portugal
    Recent Pat Biotechnol 5:183-98. 2011
    ....
  7. pmc Production of metabolites as bacterial responses to the marine environment
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisbon, Portugal
    Mar Drugs 8:705-27. 2010
    ....
  8. ncbi request reprint Biofilms: recent developments on an old battle
    Carla C C R de Carvalho
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Recent Pat Biotechnol 1:49-57. 2007
    ..Mechanical, chemical and enzymatic procedures are discussed and particular emphasis is given to the cleaning and protection of medical devices and water supply systems...
  9. ncbi request reprint Adaptation of Rhodococcus erythropolis cells to high concentrations of toluene
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Appl Microbiol Biotechnol 76:1423-30. 2007
    ..7 mg/(h mg protein). The adapted cells showed a substantially increased resistance to 50% ethanol and to concentrations of Betadine and Micropur tablets currently used in water purification, when compared to non-adapted cells...
  10. ncbi request reprint Preventing biofilm formation: promoting cell separation with terpenes
    Carla C C R de Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisboa, Portugal
    FEMS Microbiol Ecol 61:406-13. 2007
    ..The extent of cell aggregation decreased from 90% to 10% when carvone concentration reached ca. 48 mM in the organic phase...
  11. ncbi request reprint Assessment of three-dimensional biofilm structure using an optical microscope
    Carla C C R de Carvalho
    Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisbon, Portugal
    Biotechniques 42:616, 618-20. 2007
    ..The method is intended to overcome the need for expensive microscopes to study biofilms...
  12. ncbi request reprint A simple imaging method for biomass determination
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    J Microbiol Methods 60:135-40. 2005
    ..This simple method allows the assessment of growth with highly aggregated cell cultures and the rapid screening of a large number of carbon sources...
  13. ncbi request reprint The remarkable Rhodococcus erythropolis
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, Lisboa, 1049 001, Portugal
    Appl Microbiol Biotechnol 67:715-26. 2005
    ..erythropolis cells or enzymes. This large array of enzymes fully justifies the prospective application of this bacterium in biotechnology...
  14. ncbi request reprint Cell adaptation to solvent, substrate and product: a successful strategy to overcome product inhibition in a bioconversion system
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisbon, Portugal
    Appl Microbiol Biotechnol 69:268-75. 2005
    ..After an incubation period of 268 h, a final carvone concentration of 1.03 M could be attained, together with high productivity [0.19 mg carvone h(-1) (ml organic phase)(-1)] and high yield (0.96 g carvone g carveol(-1))...
  15. ncbi request reprint Adaptation of Rhodococcus erythropolis DCL14 to growth on n-alkanes, alcohols and terpenes
    Carla C C R de Carvalho
    Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Appl Microbiol Biotechnol 67:383-8. 2005
    ..This influence of the different carbon sources on the rigidity of the cell membrane also had an impact on the (-)-carvone productivity of the strain...
  16. ncbi request reprint Biotransformation of terpenes
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Lisbon, Portugal
    Biotechnol Adv 24:134-42. 2006
    ..In addition, whole cell catalysis has also been used. A variety of media and reactors have been assessed for these biotransformations and have produced encouraging results, as discussed in this review...
  17. ncbi request reprint Degradation of hydrocarbons and alcohols at different temperatures and salinities by Rhodococcus erythropolis DCL14
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    FEMS Microbiol Ecol 51:389-99. 2005
    ..The results from the conditions tested here suggest that this type of bacterium could be involved in bioremediation processes in marine environments such as the Atlantic, Pacific and Indian Ocean...
  18. doi request reprint Cell wall adaptations of planktonic and biofilm Rhodococcus erythropolis cells to growth on C5 to C16 n-alkane hydrocarbons
    Carla C C R de Carvalho
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisbon, Portugal
    Appl Microbiol Biotechnol 82:311-20. 2009
    ..erythropolis cells may be used in the development and application of sound biocatalytic processes using n-alkanes as substrates or substrate reservoirs or for target-specific bioremediation of oils and combustibles, respectively...
  19. doi request reprint Scaling-up of complex whole-cell bioconversions in conventional and non-conventional media
    Marco P C Marques
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Biotechnol Bioeng 106:619-26. 2010
    ....
  20. ncbi request reprint Solvent toxicity in organic-aqueous systems analysed by multivariate analysis
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisboa, Portugal
    Bioprocess Biosyst Eng 26:361-75. 2004
    ..cells were apparently unaffected by beta-sitosterol. The results obtained are useful for the design of more efficient two-phase reaction systems where solvent toxicity may be overcome in order to increase cell productivity...
  21. ncbi request reprint Mycobacterium sp., Rhodococcus erythropolis, and Pseudomonas putida behavior in the presence of organic solvents
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, 1049 001 Lisboa, Portugal
    Microsc Res Tech 64:215-22. 2004
    ....
  22. ncbi request reprint A simple method to observe organic solvent drops with a standard optical microscope
    Carla C C R de Carvalho
    Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, 1049 001 Lisboa, Portugal
    Microsc Res Tech 60:465-6. 2003
  23. doi request reprint Sitosterol bioconversion with resting cells in liquid polymer based systems
    Filipe Carvalho
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Lisboa, Portugal
    Bioresour Technol 100:4050-3. 2009
    ..High product yields were obtained when silicone B oil was used as substrate carrier/product pool, both in single oil and in oil:buffer two liquid phase system...
  24. pmc Burkholderia cenocepacia phenotypic clonal variation during a 3.5-year colonization in the lungs of a cystic fibrosis patient
    Carla P Coutinho
    Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001 Lisbon, Portugal
    Infect Immun 79:2950-60. 2011
    ..cenocepacia variants retrieved, along with the deterioration of pulmonary function and severe oxygen limitation...
  25. doi request reprint Adaptation of Cupriavidus necator to conditions favoring polyhydroxyalkanoate production
    João M B T Cavalheiro
    Department of Bioengineering, Universidade Tecnica de Lisboa, Lisboa, Portugal
    J Biotechnol 164:309-17. 2012
    ..The effect of GBL and PA utilization as PHA monomer precursors on the FA profile of the cell membrane was studied under two different dissolved oxygen concentrations (DOC)...
  26. doi request reprint Bioaugmentation and biostimulation strategies to improve the effectiveness of bioremediation processes
    Meenu Tyagi
    IBB Institute for Biotechnology and Bioengineering, Centre for Biological and Chemical Engineering, Instituto Superior Tecnico, Av Rovisco Pais, 1049 001, Lisbon, Portugal
    Biodegradation 22:231-41. 2011
    ..A comparative account between the two techniques and also the current scenario worldwide for in situ biotreatment using bioaugmentation and biostimulation, are addressed...