Miguel Castelo-Branco

Summary

Country: Portugal

Publications

  1. pmc Gyrification, cortical and subcortical morphometry in neurofibromatosis type 1: an uneven profile of developmental abnormalities
    Inês R Violante
    Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, Coimbra 3000 548, Portugal
    J Neurodev Disord 5:3. 2013
  2. doi request reprint Evidence of widespread retinal dysfunction in patients with stargardt disease and morphologically unaffected carrier relatives
    Susana Maia-Lopes
    Visual Neuroscience Laboratory, Centre for Ophthalmology, IBILI Institute for Biomedical Research on Light and Image, Faculty of Medicine, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 49:1191-9. 2008
  3. doi request reprint Specific impairment of visual spatial covert attention mechanisms in Parkinson's disease
    Joana Sampaio
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, 3000 548 Coimbra, Portugal
    Neuropsychologia 49:34-42. 2011
  4. ncbi request reprint Retinal and cortical patterns of spatial anisotropy in contrast sensitivity tasks
    Maria Fatima Silva
    Centre for Opthalmology, Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Az de Sta Comba, 3000 354 Coimbra, Portugal
    Vision Res 48:127-35. 2008
  5. doi request reprint Psychophysical channels and ERP population responses in human visual cortex: area summation across chromatic and achromatic pathways
    Maria J Ribeiro
    IBILI, Faculty of Medicine, University of Coimbra, Portugal
    Vision Res 50:1283-91. 2010
  6. doi request reprint Asymmetry of visual sensory mechanisms: electrophysiological, structural, and psychophysical evidences
    Maria Fatima Silva
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Coimbra, Portugal
    J Vis 10:26. 2010
  7. doi request reprint Type of featural attention differentially modulates hMT+ responses to illusory motion aftereffects
    Miguel Castelo-Branco
    Visual Neuroscience Laboratory, IBILI, University of Coimbra, Az de Sta Comba Celas, 3000 354 Coimbra, Portugal
    J Neurophysiol 102:3016-25. 2009
  8. doi request reprint Abnormal achromatic and chromatic contrast sensitivity in neurofibromatosis type 1
    Maria Jose Ribeiro
    Visual Neuroscience Laboratory, Institute of Biomedical Research in Light and Image, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 53:287-93. 2012
  9. doi request reprint GABA deficit in the visual cortex of patients with neurofibromatosis type 1: genotype-phenotype correlations and functional impact
    Inês R Violante
    IBILI, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, 3000 548 Coimbra, Portugal
    Brain 136:918-25. 2013
  10. ncbi request reprint Simultaneous comparison of relative damage to chromatic pathways in ocular hypertension and glaucoma: correlation with clinical measures
    Miguel Castelo-Branco
    Center for Ophthalmology, Department of Biophysics, Instituto Biomédico para a Investigação da Luz e Imagem, Faculty of Medicine, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 45:499-505. 2004

Collaborators

Detail Information

Publications41

  1. pmc Gyrification, cortical and subcortical morphometry in neurofibromatosis type 1: an uneven profile of developmental abnormalities
    Inês R Violante
    Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, Coimbra 3000 548, Portugal
    J Neurodev Disord 5:3. 2013
    ..Here, we investigated the volumes of subcortical structures and the composite dimensions of the cortex through analysis of cortical volume, cortical thickness, cortical surface area and gyrification...
  2. doi request reprint Evidence of widespread retinal dysfunction in patients with stargardt disease and morphologically unaffected carrier relatives
    Susana Maia-Lopes
    Visual Neuroscience Laboratory, Centre for Ophthalmology, IBILI Institute for Biomedical Research on Light and Image, Faculty of Medicine, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 49:1191-9. 2008
    ....
  3. doi request reprint Specific impairment of visual spatial covert attention mechanisms in Parkinson's disease
    Joana Sampaio
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, 3000 548 Coimbra, Portugal
    Neuropsychologia 49:34-42. 2011
    ..These findings demonstrate a specific loss of attentional mechanisms in PD and a pathological redistribution of spatial mechanisms of covert attention...
  4. ncbi request reprint Retinal and cortical patterns of spatial anisotropy in contrast sensitivity tasks
    Maria Fatima Silva
    Centre for Opthalmology, Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Az de Sta Comba, 3000 354 Coimbra, Portugal
    Vision Res 48:127-35. 2008
    ..These findings show that asymmetries in spatial vision are explained by independent retinal and cortical mechanisms...
  5. doi request reprint Psychophysical channels and ERP population responses in human visual cortex: area summation across chromatic and achromatic pathways
    Maria J Ribeiro
    IBILI, Faculty of Medicine, University of Coimbra, Portugal
    Vision Res 50:1283-91. 2010
    ..In conclusion, a fundamental relation exists between previously identified psychophysical mechanisms and population responses in the visual cortex...
  6. doi request reprint Asymmetry of visual sensory mechanisms: electrophysiological, structural, and psychophysical evidences
    Maria Fatima Silva
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Coimbra, Portugal
    J Vis 10:26. 2010
    ..We conclude that patterns of structural/functional asymmetries arise at different levels of visual processing with a strong retinal contribution...
  7. doi request reprint Type of featural attention differentially modulates hMT+ responses to illusory motion aftereffects
    Miguel Castelo-Branco
    Visual Neuroscience Laboratory, IBILI, University of Coimbra, Az de Sta Comba Celas, 3000 354 Coimbra, Portugal
    J Neurophysiol 102:3016-25. 2009
    ..Accordingly, there is a genuine MAE-related motion signal in hMT(+) that is neither explained by shifts in arousal nor by selective attention...
  8. doi request reprint Abnormal achromatic and chromatic contrast sensitivity in neurofibromatosis type 1
    Maria Jose Ribeiro
    Visual Neuroscience Laboratory, Institute of Biomedical Research in Light and Image, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 53:287-93. 2012
    ..However, low-level visual processing has not been previously investigated. Our aim was to study contrast perception in these patients to assess the function of early visual areas...
  9. doi request reprint GABA deficit in the visual cortex of patients with neurofibromatosis type 1: genotype-phenotype correlations and functional impact
    Inês R Violante
    IBILI, Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, 3000 548 Coimbra, Portugal
    Brain 136:918-25. 2013
    ..This finding is relevant to understand the physiological profile of the disorder and has implications for the identification of targets for therapeutic strategies...
  10. ncbi request reprint Simultaneous comparison of relative damage to chromatic pathways in ocular hypertension and glaucoma: correlation with clinical measures
    Miguel Castelo-Branco
    Center for Ophthalmology, Department of Biophysics, Instituto Biomédico para a Investigação da Luz e Imagem, Faculty of Medicine, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 45:499-505. 2004
    ....
  11. pmc Visual phenotype in Williams-Beuren syndrome challenges magnocellular theories explaining human neurodevelopmental visual cortical disorders
    Miguel Castelo-Branco
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Coimbra, Portugal
    J Clin Invest 117:3720-9. 2007
    ..These findings challenge neurodevelopmental theories that explain cortical deficits based on low-level magnocellular impairment, such as regarding dyslexia...
  12. doi request reprint Retinal function in best macular dystrophy: relationship between electrophysiological, psychophysical, and structural measures of damage
    Susana Maia-Lopes
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 49:5553-60. 2008
    ....
  13. doi request reprint Temporal integration of 3D coherent motion cues defining visual objects of unknown orientation is impaired in amnestic mild cognitive impairment and Alzheimer's disease
    Raquel Lemos
    IBILI, University of Coimbra, Coimbra, Portugal
    J Alzheimers Dis 28:885-96. 2012
    ..In sum, specific early dorsal stream visual impairment occurs independently of ventral stream, low-level visual and neuropsychological deficits, in amnestic types of MCI and AD...
  14. doi request reprint Independent patterns of damage to retinocortical pathways in multiple sclerosis without a previous episode of optic neuritis
    Aldina Reis
    Faculty of Medicine, Visual Neuroscience Laboratory, Institute of Biomedical Research on Light and Image IBILI, University of Coimbra, Azinhaga de Santa Comba, Celas, 3000 548 Coimbra, Portugal
    J Neurol 258:1695-704. 2011
    ..Only in this group was significant correlation of functional measures with disease stage observed, suggesting that distinct pathophysiological milestones are present before and after ON has occurred...
  15. doi request reprint Modeling epileptic brain states using EEG spectral analysis and topographic mapping
    Bruno Direito
    Center for Informatics and Systems of the University of Coimbra CISUC, University of Coimbra, Polo II, 3030 290 Coimbra, Portugal
    J Neurosci Methods 210:220-9. 2012
    ..The results suggest that the spatio-temporal dynamics captured by the proposed methodology are related to the epileptic brain states and transitions involved in focal seizures...
  16. doi request reprint Statistical spatial filtering for a P300-based BCI: tests in able-bodied, and patients with cerebral palsy and amyotrophic lateral sclerosis
    Gabriel Pires
    Institute for Systems and Robotics ISR, University of Coimbra, 3030 290 Coimbra, Portugal
    J Neurosci Methods 195:270-81. 2011
    ..33 symbols per minute with a 91.80% accuracy, corresponding to a bandwidth of 19.18 bits per minute. This study shows the feasibility of the proposed methodology and that effective communication rates are achievable...
  17. doi request reprint Object based implicit contextual learning: a study of eye movements
    Marieke Van Asselen
    IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Atten Percept Psychophys 73:297-302. 2011
    ..This indicates that by memorizing associations between objects in our environment we can recognize objects faster, thereby facilitating visual search...
  18. doi request reprint Motion integration deficits are independent of magnocellular impairment in Parkinson's disease
    Miguel Castelo-Branco
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, 3000 458 Coimbra, Portugal
    Neuropsychologia 47:314-20. 2009
    ..We conclude that dorsal stream deficits in PD have a high-level visual cortical basis independent of low-level magnocellular damage...
  19. doi request reprint GIBS block speller: toward a gaze-independent P300-based BCI
    Gabriel Pires
    Institute for Systems and Robotics, University of Coimbra, 3000 Coimbra, Portugal
    Conf Proc IEEE Eng Med Biol Soc 2011:6360-4. 2011
    ..Furthermore, with overt attention, the results show that the improved classification accuracy of GIBS over RC speller compensates the extra selections, thereby achieving similar practical bit rates...
  20. doi request reprint Comparison of a row-column speller vs. a novel lateral single-character speller: assessment of BCI for severe motor disabled patients
    Gabriel Pires
    Institute for Systems and Robotics, University of Coimbra, 3030 290 Coimbra, Portugal
    Clin Neurophysiol 123:1168-81. 2012
    ..This paper presents a novel P300-based speller called lateral single-character (LSC). The LSC performance is compared to that of the standard row-column (RC) speller...
  21. doi request reprint Peripheral influences on motion integration in foveal vision are modulated by central local ambiguity and center-surround congruence
    Lajos R Kozak
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Invest Ophthalmol Vis Sci 50:980-8. 2009
    ..To study how central visual motion integration and segmentation processes are influenced by the congruence or incongruence of peripheral contextual moving surrounds and to determine their clinical relevance...
  22. pmc Aging of low and high level vision: from chromatic and achromatic contrast sensitivity to local and 3D object motion perception
    Catarina Mateus
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Coimbra, Portugal
    PLoS ONE 8:e55348. 2013
    ....
  23. doi request reprint Implicit contextual learning in prodromal and early stage Huntington's disease patients
    Marieke Van Asselen
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Portugal
    J Int Neuropsychol Soc 18:689-96. 2012
    ..The results of the current study indicate that both prodromal and symptomatic HD participants are impaired on an implicit contextual learning task...
  24. doi request reprint Developmental dissociation of visual dorsal stream parvo and magnocellular representations and the functional impact of negative retinotopic BOLD responses
    Isabel Catarina Duarte
    Brain Imaging Network, ICNAS, Azinhaga de Santa Comba, 3000 058 Coimbra, Portugal Institute for Biomedical Imaging and Life Sciences, IBILI, Azinhaga de Santa Comba, 3000 548 Coimbra, Portugal Electronic address
    Brain Cogn 83:72-9. 2013
    ....
  25. pmc Scanning Patterns of Faces do not Explain Impaired Emotion Recognition in Huntington Disease: Evidence for a High Level Mechanism
    Marieke Van Asselen
    Visual Neuroscience Laboratory, Faculty of Medicine, Institute of Biomedical Research in Light and Image, University of Coimbra Coimbra, Portugal
    Front Psychol 3:31. 2012
    ..Furthermore, no selective deficit for recognition of disgust was found in pre-symptomatic HD patients...
  26. doi request reprint Adaptive visual memory reorganization in right medial temporal lobe epilepsy
    Patricia Figueiredo
    IBILI, Department of Biophysics, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Epilepsia 49:1395-408. 2008
    ..We investigated functional reorganization mechanisms of the human medial temporal lobe (MTL) for episodic memory, in patients suffering from medial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS)...
  27. doi request reprint Neural correlates of visual integration in Williams syndrome: gamma oscillation patterns in a model of impaired coherence
    Inês Bernardino
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Neuropsychologia 51:1287-95. 2013
    ....
  28. doi request reprint Egocentric and allocentric spatial representations in Williams syndrome
    Inês Bernardino
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    J Int Neuropsychol Soc 19:54-62. 2013
    ..Interestingly, the difficulties found in performing allocentric spatial judgments give important cues to better understand the ventral visual functioning in WS...
  29. doi request reprint Long term cortical plasticity in visual retinotopic areas in humans with silent retinal ganglion cell loss
    Otília C d'Almeida
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, University of Coimbra, Portugal Electronic address
    Neuroimage 81:222-30. 2013
    ..This form of structural plasticity suggests enhanced plastic developmental mechanisms in extrastriate retinotopic regions close to V1 and not receiving direct retinocortical input. ..
  30. pmc A direct comparison of local-global integration in autism and other developmental disorders: implications for the central coherence hypothesis
    Inês Bernardino
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Coimbra, Portugal
    PLoS ONE 7:e39351. 2012
    ..Taken together these findings suggest that other mechanisms such as dorsal stream deficits (largest in WS) may underlie impaired central coherence...
  31. doi request reprint Functional parcellation of the operculo-insular cortex in perceptual decision making: an fMRI study
    José Rebola
    Visual Neuroscience Laboratory, Institute for Biomedical Imaging in Light and Image, Faculty of Medicine, University of Coimbra, Azinhaga de Sta Comba, 3000 548 Coimbra, Portugal
    Neuropsychologia 50:3693-701. 2012
    ..We conclude that global perceptual integration based on holistic rules requires a distributed operculo-insular network...
  32. doi request reprint Visual P300-based BCI to steer a wheelchair: a Bayesian approach
    Gabriel Pires
    Institute for Systems and Robotics, University of Coimbra, 3000, Portugal
    Conf Proc IEEE Eng Med Biol Soc 2008:658-61. 2008
    ..The classification algorithms were obtained offline from training and then validated offline and online. The system achieved a transfer rate of 7 commands/min with 95% false positive classification accuracy...
  33. pmc To Perceive or Not Perceive: The Role of Gamma-band Activity in Signaling Object Percepts
    João Castelhano
    Visual Neuroscience Laboratory, Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    PLoS ONE 8:e66363. 2013
    ....
  34. doi request reprint Space time frequency (STF) code tensor for the characterization of the epileptic preictal stage
    Bruno Direito
    Center for Informatics and Systems, University of Coimbra, 3030 Coimbra, Portugal
    Conf Proc IEEE Eng Med Biol Soc 2012:621-4. 2012
    ..Furthermore, the spatial signature may be related to the ictal onset region and that determined frequency sub-bands may be more relevant in preictal stages...
  35. doi request reprint Physiological evidence for impairment in autosomal dominant optic atrophy at the pre-ganglion level
    Aldina Reis
    Visual Neuroscience Laboratory, Institute of Biomedical Research on Light and Image, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    Graefes Arch Clin Exp Ophthalmol 251:221-34. 2013
    ..Here we aimed to investigate the impact of the disease at a pre-GC level and its correlation with GC/post-GC related measures...
  36. pmc Abnormal brain activation in neurofibromatosis type 1: a link between visual processing and the default mode network
    Inês R Violante
    Visual Neuroscience Laboratory, Institute of Biomedical Research in Light and Image, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    PLoS ONE 7:e38785. 2012
    ..A link between magnocellular and default mode network processing may generalize to neuropsychiatric disorders where such deficits have been separately identified...
  37. ncbi request reprint Visual magnocellular and structure from motion perceptual deficits in a neurodevelopmental model of dorsal stream function
    Mafalda Mendes
    Centre for Ophthalmology, IBILI, Faculty of Medicine, Az de Sta Comba, 3000 354 Coimbra, Portugal
    Brain Res Cogn Brain Res 25:788-98. 2005
    ..Finally, selective SFM coherence deficits support the proposal that there is a specific pathway in the dorsal stream that is involved in motion processing of 3D surfaces, which seems to be impaired in this disorder...
  38. ncbi request reprint Quantitative phenotyping of chromatic dysfunction in best macular dystrophy
    Sónia H Campos
    Center for Ophthalmology, Institute of Biomedical Research in Light and Image, Faculty of Medicine, University of Coimbra, Az de Sta Comba, Celas 3000 354, Coimbra, Portugal
    Arch Ophthalmol 123:944-9. 2005
    ..To quantify chromatic dysfunction in Best disease to reassess the classic categorization of macular chromatic damage and to investigate psychophysical and clinical correlations...
  39. pmc Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat
    Joao Martins
    Centre of Ophthalmology and Vision Sciences, IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
    PLoS ONE 6:e29583. 2011
    ..These changes in photoreceptor/bipolar cell physiology may have implications for the understanding of the subacute visual manifestations induced by MDMA in humans...
  40. doi request reprint ICA decomposition of EEG signal for fMRI processing in epilepsy
    Jose P Marques
    Visual Neuroscience Lab, IBILI, University of Coimbra, Portugal
    Hum Brain Mapp 30:2986-96. 2009
    ..Furthermore, the three cases where an agreement was not found were those in which no significant activation was found at all using the conventional approach...
  41. pmc ABCA4 mutations in Portuguese Stargardt patients: identification of new mutations and their phenotypic analysis
    Susana Maia-Lopes
    Visual Neuroscience Laboratory, IBILI, Faculty of Medicine, Coimbra, Portugal
    Mol Vis 15:584-91. 2009
    ....