Walter J Pories

Summary

Publications

  1. ncbi request reprint Yes, Virginia, bariatric surgery works, and it is safe
    Walter J Pories
    Metabolic Institute, Biochemistry, Sport and Exercise Science, Brody School of Medicine, East Carolina University, USA
    N C Med J 67:296-300. 2006
  2. ncbi request reprint New technologies for treating obesity
    D M Bermudez
    East Carolina University, Greenville, NC, USA
    Minerva Endocrinol 38:165-72. 2013
  3. ncbi request reprint So you think we are bariatric surgeons? Think again
    Walter J Pories
    Eastern Carolina University School of Medicine, Greenville, NC 27858, USA
    Obes Surg 13:673-5. 2003
  4. doi request reprint Beyond the BMI: the search for better guidelines for bariatric surgery
    Walter J Pories
    Department of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA
    Obesity (Silver Spring) 18:865-71. 2010
  5. doi request reprint The surgical treatment of type two diabetes mellitus
    Walter J Pories
    Division of Bariatric Surgery, Department of Surgery, The Brody School of Medicine, East Carolina University, 600 Moye Boulevard, Brody Medical Science 4W 48, Mail Stop 639, Greenville, NC 27834, USA
    Surg Clin North Am 91:821-36, viii. 2011
  6. pmc Bariatric surgery: risks and rewards
    Walter J Pories
    East Carolina University, Greenville, North Carolina 27834, USA
    J Clin Endocrinol Metab 93:S89-96. 2008
  7. ncbi request reprint Effect of weight loss on muscle lipid content in morbidly obese subjects
    Robert E Gray
    Department of Exercise and Sport Science, East Carolina University, Greenville, North Carolina 27858, USA
    Am J Physiol Endocrinol Metab 284:E726-32. 2003
  8. ncbi request reprint Ethnic differences in adiponectin levels
    Matthew W Hulver
    Department of Physiology, East Carolina University, Brody School of Medicine, Greenville, NC 27858, USA
    Metabolism 53:1-3. 2004
  9. pmc Mechanism for improved insulin sensitivity after gastric bypass surgery
    Benjamin T Bikman
    The Metabolic Institute for the Study of Diabetes and Obesity, East Carolina University, 6N98 600 Moye Boulevard, Greenville, North Carolina 27834, USA
    J Clin Endocrinol Metab 93:4656-63. 2008
  10. doi request reprint Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes
    Melissa A Reed
    Department of Exercise and Sport Science, Brody Medical School, East Carolina University, Greenville, North Carolina 27834, USA
    J Clin Endocrinol Metab 96:2525-31. 2011

Research Grants

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Yes, Virginia, bariatric surgery works, and it is safe
    Walter J Pories
    Metabolic Institute, Biochemistry, Sport and Exercise Science, Brody School of Medicine, East Carolina University, USA
    N C Med J 67:296-300. 2006
  2. ncbi request reprint New technologies for treating obesity
    D M Bermudez
    East Carolina University, Greenville, NC, USA
    Minerva Endocrinol 38:165-72. 2013
    ..This article will review the most recent advances in innovative technologies to treat the growing numbers of obese patients...
  3. ncbi request reprint So you think we are bariatric surgeons? Think again
    Walter J Pories
    Eastern Carolina University School of Medicine, Greenville, NC 27858, USA
    Obes Surg 13:673-5. 2003
  4. doi request reprint Beyond the BMI: the search for better guidelines for bariatric surgery
    Walter J Pories
    Department of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA
    Obesity (Silver Spring) 18:865-71. 2010
    ..Further, with increasing evidence that bariatric surgery can also induce full and durable remission of such comorbidities as type 2 diabetes even in patients with BMIs <30, new guidelines must be pursued...
  5. doi request reprint The surgical treatment of type two diabetes mellitus
    Walter J Pories
    Division of Bariatric Surgery, Department of Surgery, The Brody School of Medicine, East Carolina University, 600 Moye Boulevard, Brody Medical Science 4W 48, Mail Stop 639, Greenville, NC 27834, USA
    Surg Clin North Am 91:821-36, viii. 2011
    ..This article examines four surgical procedures and their outcomes...
  6. pmc Bariatric surgery: risks and rewards
    Walter J Pories
    East Carolina University, Greenville, North Carolina 27834, USA
    J Clin Endocrinol Metab 93:S89-96. 2008
    ..Of even greater concern is the association of the adiposity with comorbidities such as diabetes, hypertension, cardiopulmonary failure, asthma, pseudotumor cerebri, infertility, and crippling arthritis...
  7. ncbi request reprint Effect of weight loss on muscle lipid content in morbidly obese subjects
    Robert E Gray
    Department of Exercise and Sport Science, East Carolina University, Greenville, North Carolina 27858, USA
    Am J Physiol Endocrinol Metab 284:E726-32. 2003
    ..This reduction in intramuscular triglyceride may contribute to enhanced insulin action seen with weight loss...
  8. ncbi request reprint Ethnic differences in adiponectin levels
    Matthew W Hulver
    Department of Physiology, East Carolina University, Brody School of Medicine, Greenville, NC 27858, USA
    Metabolism 53:1-3. 2004
    ....
  9. pmc Mechanism for improved insulin sensitivity after gastric bypass surgery
    Benjamin T Bikman
    The Metabolic Institute for the Study of Diabetes and Obesity, East Carolina University, 6N98 600 Moye Boulevard, Greenville, North Carolina 27834, USA
    J Clin Endocrinol Metab 93:4656-63. 2008
    ..Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity...
  10. doi request reprint Roux-en-Y gastric bypass corrects hyperinsulinemia implications for the remission of type 2 diabetes
    Melissa A Reed
    Department of Exercise and Sport Science, Brody Medical School, East Carolina University, Greenville, North Carolina 27834, USA
    J Clin Endocrinol Metab 96:2525-31. 2011
    ..Roux-en-Y gastric bypass (RYGB) has been shown to induce rapid and durable reversal of type 2 diabetes...
  11. doi request reprint Amelioration of insulin requirement in patients undergoing duodenal bypass for reasons other than obesity implicates foregut factors in the pathophysiology of type II diabetes
    Emmanuel E Zervos
    Division of Surgical Oncology, Department of Surgery, East Carolina University, Greenville, NC, USA
    J Am Coll Surg 210:564-72, 572-4. 2010
    ..To support or refute the role of the foregut, we analyzed glycemic control in T2DM patients before and after foregut bypass for reasons other than morbid obesity...
  12. ncbi request reprint Fatty acid oxidation by skeletal muscle homogenates from morbidly obese black and white American women
    Jonathan D Privette
    Department of Biochemistry, East Carolina University, Greenville, NC 27858, USA
    Metabolism 52:735-8. 2003
    ..The decreased fatty acid oxidation by skeletal muscle of obese Black women could result in shunting these fuels from muscle to adipose tissue for storage, which may contribute to the maintenance of obesity in the Black women...
  13. doi request reprint GLP-1 response to a mixed meal: what happens 10 years after Roux-en-Y gastric bypass (RYGB)?
    Moahad S Dar
    Department of Internal Medicine, Section of Endocrinology and Metabolism, Brody School of Medicine at East Carolina University, 3E 129 Brody Building, 600 Moye Boulevard, Greenville, NC 27834, USA
    Obes Surg 22:1077-83. 2012
    ..This effect is exaggerated during short-term follow-up of Roux-en-y gastric bypass (RYGB). We examined the durability of this effect in patient with type 2 diabetes (T2DM) >10 years after RYGB...
  14. ncbi request reprint Adiponectin is not altered with exercise training despite enhanced insulin action
    Matthew W Hulver
    Department of Physiology, East Carolina University, Greenville North Carolina 27858, USA
    Am J Physiol Endocrinol Metab 283:E861-5. 2002
    ..These data suggest that adiponectin is not a contributory factor to the exercise-related improvements in insulin sensitivity...
  15. ncbi request reprint Endothelial nitric oxide synthase content in adipose tissue from obese and lean African American and white American women
    Vaughna B Galvin
    Human Performance Laboratory, Department of Exercise and Sports Science, East Carolina University, Greenville, NC 27858, USA
    Metabolism 54:1368-73. 2005
    ....
  16. ncbi request reprint Effect of weight loss on insulin sensitivity and intramuscular long-chain fatty acyl-CoAs in morbidly obese subjects
    Joseph A Houmard
    Department of Exercise and Sport Science, and the Human Performance Laboratory and Diabetes Obesity Center, East Carolina University, Greenville, North Carolina 27858, USA
    Diabetes 51:2959-63. 2002
    ..These data suggest that a reduction in intramuscular LCACoA content may be responsible, at least in part, for the enhanced insulin action observed with weight loss in obese individuals...
  17. ncbi request reprint Skeletal muscle lipid metabolism with obesity
    Matthew W Hulver
    Department of Physiology, The Brody School of Medicine, East Carolina University, Greenville, North Carolina 27858, USA
    Am J Physiol Endocrinol Metab 284:E741-7. 2003
    ....
  18. ncbi request reprint Quality assurance in bariatric surgery
    Stewart E Rendon
    Division of Bariatric Surgery, Brody School of Medicine at East Carolina University, 600 Moye Boulevard, Greenville, NC 27834, USA
    Surg Clin North Am 85:757-71, vi-vii. 2005
    ....
  19. ncbi request reprint Bariatric surgery: what is the effect on type 2 diabetes?
    Moahad Dar
    Department of Surgery, East Carolina University, Brody School of Medicine, Greenville, NC 27834, USA
    Curr Opin Investig Drugs 10:1078-84. 2009
    ..This review discusses the known effects of bariatric surgery on T2DM, with a particular focus on Roux-en-Y gastric bypass...
  20. ncbi request reprint Epidemiology of obesity in the United States
    John R Pender
    Brody School of Medicine, Department of Surgery, East Carolina University, Brody Medical Science Building, 2E 67 Greenville, NC 27858, USA
    Gastroenterol Clin North Am 34:1-7. 2005
    ..Without a plan of education to promote nutrition and increased physical activity, and continued research into the causes of obesity, the prevalence of obesity will continue to rise in the United States...
  21. ncbi request reprint Surgical treatment of obesity
    John R Pender
    Department of Surgery, Brody School of Medicine, East Carolina University, Brody Medical Science Building, 2E 67 Greenville, NC 27858, USA
    Psychiatr Clin North Am 28:219-34, x. 2005
  22. doi request reprint Early postoperative outcomes of metabolic surgery to treat diabetes from sites participating in the ASMBS bariatric surgery center of excellence program as reported in the Bariatric Outcomes Longitudinal Database
    Eric J Demaria
    Department of Surgery, Duke University, Durham, NC, USA
    Ann Surg 252:559-66; discussion 566-7. 2010
    ....
  23. pmc Severe obesity: evidence for a deranged metabolic program in skeletal muscle?
    Joseph A Houmard
    Department of Kinesiology and Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, NC 27858, USA
    Exerc Sport Sci Rev 40:204-10. 2012
    ..We believe that this represents a paradigm shift in thinking about metabolic regulation in obesity...
  24. doi request reprint Surgical treatment of metabolic syndrome
    Sharon Williams
    Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA
    Med Princ Pract 21:301-9. 2012
    ..If either of these mechanisms is proven correct, the current treatment of diabetes with long-term insulin administration deserves review...
  25. ncbi request reprint Muscle fiber type is associated with obesity and weight loss
    Charles J Tanner
    Department of Exercise and Sport Science, East Carolina University, Greenville, North Carolina 27858, USA
    Am J Physiol Endocrinol Metab 282:E1191-6. 2002
    ..72, P < 0.005) between the percentage of excess weight loss and the percentage of type I fibers in morbidly obese patients. These findings indicate that there is a relationship between muscle fiber type and obesity...
  26. pmc Duodenal-jejunal bypass surgery does not increase skeletal muscle insulin signal transduction or glucose disposal in Goto-Kakizaki type 2 diabetic rats
    Timothy P Gavin
    Human Performance Laboratory, East Carolina University, Greenville, NC 27858, USA
    Obes Surg 21:231-7. 2011
    ..It was hypothesized that DJB would increase skeletal muscle insulin signal transduction and glucose disposal in GK rats...
  27. doi request reprint Mobilization of the obese patient and prevention of injury
    Christine M Walden
    Vidant Medical Center Brody School of Medicine, East Carolina University, Greenville, NC
    Ann Surg 258:646-50; discussion 650-1. 2013
    ..Each move, along with turning, bathing, and access to bathrooms, poses risks of injury to patients and personnel. Similarly, inadequate mobilization raises the risk of pressure ulcers. The costs can be prohibitive...
  28. doi request reprint Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis
    Henry Buchwald
    Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Med 122:248-256.e5. 2009
    ..The objective of this review and meta-analysis is to determine the impact of bariatric surgery on type 2 diabetes in association with the procedure performed and the weight reduction achieved...
  29. pmc Is there a metabolic program in the skeletal muscle of obese individuals?
    Joseph A Houmard
    Department of Exercise and Sport Science, College of Health and Human Performance, East Carolina University, Greenville, NC 27834, USA
    J Obes 2011:250496. 2011
    ..Findings presented in this review will hopefully increase the understanding of and aid in preventing and/or treating the severely obese condition...
  30. pmc What distinguishes adipose tissue of severely obese humans who are insulin sensitive and resistant?
    X Julia Xu
    Diabetes and Metabolism Unit, Section of Endocrinology, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, USA
    Curr Opin Lipidol 24:49-56. 2013
    ..In this review, we will examine the factors in adipose tissue that distinguish the two groups, as well as reasons for believing the insulin-sensitive group will be less disease prone...
  31. pmc Massive weight loss-induced mechanical plasticity in obese gait
    Tibor Hortobagyi
    Department of Exercise and Sport Science, East CarolinaUniversity, Greenville, North Carolina, USA
    J Appl Physiol (1985) 111:1391-9. 2011
    ..There may be a weight loss threshold of 30 kg limiting changes in gait kinematics. Implications for exercise prescription are also discussed...
  32. doi request reprint Expanded Occupational Safety and Health Administration 300 log as metric for bariatric patient-handling staff injuries
    Stephen B Randall
    Department of Ergonomics, Pitt County Memorial Hospital, Greenville, North Carolina 27835 6028, USA
    Surg Obes Relat Dis 5:463-8. 2009
    ....
  33. ncbi request reprint Centers of Excellence for Bariatric Surgery
    J Kenneth Champion
    Department of Surgery, Emory Dunwoody Medical Center, Atlanta, Georgia, USA
    Surg Obes Relat Dis 1:148-51. 2005
  34. ncbi request reprint The ASBS Bariatric Surgery Centers of Excellence program: a blueprint for quality improvement
    Gary M Pratt
    Surgical Review Corporation, Raleigh, North Carolina, USA
    Surg Obes Relat Dis 2:497-503; discussion 503. 2006
    ....
  35. ncbi request reprint Body mass index and outcomes in critically injured blunt trauma patients: weighing the impact
    Mark A Newell
    Department of Surgery, The Brody School of Medicine, East Carolina University, Center of Excellence for Trauma and Surgical Critical Care, University Health Systems of Eastern North Carolina, Greenville, NC 27858 4354, USA
    J Am Coll Surg 204:1056-61; discussion 1062-4. 2007
    ..The objective of this study was to investigate the relationship between stratified BMI and outcomes in blunt injured patients...
  36. pmc Diabetes: the evolution of a new paradigm
    Walter J Pories
    Ann Surg 239:12-3. 2004
  37. ncbi request reprint Improving diabetes care in North Carolina
    Walter J Pories
    N C Med J 64:138-9. 2003
  38. ncbi request reprint Expression of genes regulating malonyl-CoA in human skeletal muscle
    Celia Pender
    Department of Medicine, Diabetes and Endocrine Research, Mount Zion Medical Center, University of California, San Francisco, California 94143 1616, USA
    J Cell Biochem 99:860-7. 2006
    ..No other genes showed signs of increased mRNA content with obesity, suggesting that there may be selective transcriptional regulation of malonyl-CoA metabolism in human obesity...
  39. ncbi request reprint Ghrelin? Yes, it is spelled correctly
    Walter J Pories
    Ann Surg 247:408-10. 2008
  40. pmc Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery
    Steven H Belle
    Data Coordinating Center, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    Surg Obes Relat Dis 3:116-26. 2007
    ..To facilitate research in this field, the National Institute of Diabetes and Digestive and Kidney Diseases responded to this knowledge gap by establishing the Longitudinal Assessment of Bariatric Surgery (LABS) consortium...
  41. ncbi request reprint Medicare and bariatric surgery
    John G Kral
    American Society for Bariatric Surgery, Gainesville, Florida 32607, USA
    Surg Obes Relat Dis 1:35-63. 2005
  42. ncbi request reprint Surgery as an effective early intervention for diabesity: why the reluctance?
    John B Dixon
    Centre for Obesity Research and Education, Monash University, Alfred Hospital, Melbourne 3181, Australia
    Diabetes Care 28:472-4. 2005
  43. ncbi request reprint Suppression of hepatic cholesteryl ester transfer protein expression in obese humans with the development of type 2 diabetes mellitus
    Paul S MacLean
    University of Colorado Health Sciences Center, Center for Human Nutrition, 4200 East 9th Avenue, C225, Denver, Colorado 80262, USA
    J Clin Endocrinol Metab 90:2250-8. 2005
    ..Thus, the suppressive effects of type 2 diabetes in obese subjects are observed in both men and women and may be due, at least in part, to a suppression of hepatic CETP expression...
  44. ncbi request reprint Research considerations in obesity surgery
    John G Kral
    American Society for Bariatric Surgery, Gainesville, Florida, USA
    Obes Res 10:63-4. 2002

Research Grants1

  1. Eact Carolina Univ. Bariatric Surgery Clinical Center
    Walter Pories; Fiscal Year: 2007
    ..abstract_text> ..