Karthe Ponnuraj

Summary

Publications

  1. pmc Expression, purification, crystallization and preliminary crystallographic analysis of laminin-binding protein (Lmb) from Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65:492-4. 2009
  2. doi request reprint Collagen adhesin-nanoparticle interaction impairs adhesin's ligand binding mechanism
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochim Biophys Acta 1820:819-28. 2012
  3. doi request reprint Crystal structure of the first plant urease from jack bean: 83 years of journey from its first crystal to molecular structure
    Anuradha Balasubramanian
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    J Mol Biol 400:274-83. 2010
  4. pmc Metal binding is critical for the folding and function of laminin binding protein, Lmb of Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai, India
    PLoS ONE 8:e67517. 2013
  5. pmc Crystallization, characterization and preliminary X-ray crystallographic analysis of GK2848, a putative carbonic anhydrase of Geobacillus kaustophilus
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 69:162-4. 2013
  6. doi request reprint Structure of laminin-binding adhesin (Lmb) from Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr D Biol Crystallogr 65:1262-9. 2009
  7. doi request reprint Crystal structure of type I 3-dehydroquinate dehydratase of Aquifex aeolicus suggests closing of active site flap is not essential for enzyme action
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochem Biophys Res Commun 432:350-4. 2013
  8. doi request reprint The structure of putative N-acetyl glutamate kinase from Thermus thermophilus reveals an intermediate active site conformation of the enzyme
    Ramya Sundaresan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochem Biophys Res Commun 420:692-7. 2012
  9. doi request reprint Expression, purification and structural analysis of a fibrinogen receptor FbsA from Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600025, India
    Protein J 30:159-66. 2011
  10. doi request reprint Cloning, expression, purification and ligand binding studies of novel fibrinogen-binding protein FbsB of Streptococcus agalactiae
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai, India
    Protein Expr Purif 74:148-55. 2010

Collaborators

Detail Information

Publications17

  1. pmc Expression, purification, crystallization and preliminary crystallographic analysis of laminin-binding protein (Lmb) from Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65:492-4. 2009
    ..The crystals diffracted to a resolution of 2.5 A and belonged to the monoclinic space group P2(1), with unit-cell parameters a = 56.63, b = 70.60, c = 75.37 A, beta = 96.77 degrees ...
  2. doi request reprint Collagen adhesin-nanoparticle interaction impairs adhesin's ligand binding mechanism
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochim Biophys Acta 1820:819-28. 2012
    ..With the rapid rise in antibiotic resistance, designing alternative strategies to reduce/eliminate bacterial colonization is absolutely essential...
  3. doi request reprint Crystal structure of the first plant urease from jack bean: 83 years of journey from its first crystal to molecular structure
    Anuradha Balasubramanian
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    J Mol Biol 400:274-83. 2010
    ....
  4. pmc Metal binding is critical for the folding and function of laminin binding protein, Lmb of Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai, India
    PLoS ONE 8:e67517. 2013
    ..Targeted mutations of histidine residues confirmed the importance of the zinc binding crevice for the structure and function of the Lmb adhesin. ..
  5. pmc Crystallization, characterization and preliminary X-ray crystallographic analysis of GK2848, a putative carbonic anhydrase of Geobacillus kaustophilus
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 69:162-4. 2013
    ..The structure and functional analysis of GK2848 might provide valuable information on a novel class of carbonic anhydrases, as none of its homologous structures have been characterized...
  6. doi request reprint Structure of laminin-binding adhesin (Lmb) from Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr D Biol Crystallogr 65:1262-9. 2009
    ..Being ubiquitous in all serotypes of group B streptococcus (GBS), the structure of Lmb may direct the development of an efficient vaccine...
  7. doi request reprint Crystal structure of type I 3-dehydroquinate dehydratase of Aquifex aeolicus suggests closing of active site flap is not essential for enzyme action
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochem Biophys Res Commun 432:350-4. 2013
    ..This provides new insights into the catalytic mechanism of type I 3-DHQases...
  8. doi request reprint The structure of putative N-acetyl glutamate kinase from Thermus thermophilus reveals an intermediate active site conformation of the enzyme
    Ramya Sundaresan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochem Biophys Res Commun 420:692-7. 2012
    ..The structural comparison of TtNAGK with EcNAGK revealed the structural basis of thermostability of TtNAGK and this information could be very useful to generate mutants of NAGK with increased overall stability...
  9. doi request reprint Expression, purification and structural analysis of a fibrinogen receptor FbsA from Streptococcus agalactiae
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600025, India
    Protein J 30:159-66. 2011
    ....
  10. doi request reprint Cloning, expression, purification and ligand binding studies of novel fibrinogen-binding protein FbsB of Streptococcus agalactiae
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai, India
    Protein Expr Purif 74:148-55. 2010
    ..FbsB(C) indeed is a novel protein and understanding the mechanism of its interaction with Fg would be useful in developing strategies to fight against infections by Streptococcus...
  11. pmc Cloning, expression, purification, crystallization and preliminary crystallographic analysis of the N-terminal domain of serine glutamate repeat A (SgrA) protein from Enterococcus faecium
    Revathi Nagarajan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 69:441-4. 2013
    ..The native rSgrA(28-153) protein crystallized in the monoclinic space group P2(1) and diffracted to 3.3 Å resolution using an in-house X-ray source, with unit-cell parameters a = 35.84, b = 56.35, c = 60.20 Å, β = 106.5°...
  12. pmc Expression, purification, crystallization and preliminary X-ray diffraction studies of the human keratin 4-binding domain of serine-rich repeat protein 1 from Streptococcus agalactiae
    Ramya Sundaresan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1582-5. 2011
    ..The crystals diffracted to 3.8 Å resolution using synchrotron radiation and belonged to space group P2(1), with unit-cell parameters a = 47.56, b = 59.48, c = 94.71 Å, β = 93.95°...
  13. pmc Purification, crystallization and preliminary X-ray analysis of urease from pigeon pea (Cajanus cajan)
    Anuradha Balasubramanian
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64:662-4. 2008
    ..The pigeon pea urease was crystallized and the resulting crystals diffracted to 2.5 A resolution. The crystals belong to the rhombohedral space group R32, with unit-cell parameters a = b = 176.29, c = 346.44 A...
  14. pmc Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the collagen-binding region of RspB from Erysipelothrix rhusiopathiae
    Aribam Swarmistha Devi
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 66:156-9. 2010
    ..2 A using synchrotron radiation. The crystals belonged to the monoclinic space group P2(1), with unit-cell parameters a = 46.19, b = 66.65, c = 101.72 A, beta = 94.11 degrees ...
  15. pmc Purification, crystallization and preliminary X-ray analysis of urease from jack bean (Canavalia ensiformis)
    Anuradha Balasubramanian
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai, India
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65:949-51. 2009
    ..05 A resolution using synchrotron radiation. The crystals belonged to the hexagonal space group P6(3)22, with unit-cell parameters a = b = 138.57, c = 198.36 A...
  16. ncbi request reprint Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of glyceraldehyde-3-phosphate dehydrogenase from Streptococcus agalactiae NEM316
    Revathi Nagarajan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Acta Crystallogr F Struct Biol Commun 70:938-41. 2014
    ..8 and 2.6 Å resolution, belonging to two different space groups P21 and P212121, respectively. The structure was solved by molecular replacement and structure refinement is now in progress. ..
  17. doi request reprint Crystal structure of ST2348, a CBS domain protein, from hyperthermophilic archaeon Sulfolobus tokodaii
    Preethi Ragunathan
    Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India
    Biochem Biophys Res Commun 375:124-8. 2008
    ....