S Ponmariappan

Summary

Publications

  1. ncbi Antibodies against recombinant catalytic domain of lethal toxin of Clostridium sordellii neutralize lethal toxin toxicity in HeLa cells
    Preetika Arya
    Biotechnology Division, Defence Research and Development Establishment, Gwalior 474002, M P, India
    Protein Pept Lett 20:205-12. 2013
  2. ncbi Expression, purification and development of neutralizing antibodies from synthetic BoNT/B LC and its application in detection of botulinum toxin serotype B
    S Ponmariappan
    Biotechnology Division, Defence Research and Development Establishment, Gwalior, Madhya Pradesh, India
    Protein Pept Lett 19:288-98. 2012
  3. ncbi Development of immunodetection system for botulinum neurotoxin type B using synthetic gene based recombinant protein
    Swati Jain
    Biotechnology Division, Defence Research Development and Establishment, Gwalior, India
    Indian J Med Res 134:33-9. 2011
  4. ncbi Effect of adjuvants on antibody titer of synthetic recombinant light chain of botulinum neurotoxin type B and its diagnostic potential for botulism
    Swati Jain
    Biotechnology Division, Defence Research and Development Establishment, Jhansi Road, Gwalior 474 002, Madhya Pradesh, India
    J Microbiol Biotechnol 21:719-27. 2011

Collaborators

  • Swati Jain
  • Preetika Arya
  • Lokendra Singh
  • G B K S Prasad

Detail Information

Publications4

  1. ncbi Antibodies against recombinant catalytic domain of lethal toxin of Clostridium sordellii neutralize lethal toxin toxicity in HeLa cells
    Preetika Arya
    Biotechnology Division, Defence Research and Development Establishment, Gwalior 474002, M P, India
    Protein Pept Lett 20:205-12. 2013
    ..difficile native toxins in HeLa cells. Mice and rabbit anti-rTcsL sera effectively neutralized the cytotoxicity of rTcsL and C. sordellii native toxin but it did not neutralize the cytotoxicity of C. difficile toxin in HeLa cells...
  2. ncbi Expression, purification and development of neutralizing antibodies from synthetic BoNT/B LC and its application in detection of botulinum toxin serotype B
    S Ponmariappan
    Biotechnology Division, Defence Research and Development Establishment, Gwalior, Madhya Pradesh, India
    Protein Pept Lett 19:288-98. 2012
    ..These developed high titer antibodies may prove useful for the detection of botulinum neurotoxins in food and clinical samples...
  3. ncbi Development of immunodetection system for botulinum neurotoxin type B using synthetic gene based recombinant protein
    Swati Jain
    Biotechnology Division, Defence Research Development and Establishment, Gwalior, India
    Indian J Med Res 134:33-9. 2011
    ..So far, there is no commercial detection system available in India to detect botulism. The present study aims to develop an immuno detection system for botulinum neurotoxin serotype B using synthetic gene approach...
  4. ncbi Effect of adjuvants on antibody titer of synthetic recombinant light chain of botulinum neurotoxin type B and its diagnostic potential for botulism
    Swati Jain
    Biotechnology Division, Defence Research and Development Establishment, Jhansi Road, Gwalior 474 002, Madhya Pradesh, India
    J Microbiol Biotechnol 21:719-27. 2011
    ..These developed high-titer antibodies may prove useful for the detection of botulinum neurotoxins in food and clinical samples...