Ewa Stachowska

Summary

Affiliation: University of Szczecin
Country: Poland

Publications

  1. doi request reprint Conjugated linoleic acid isomers may diminish human macrophages adhesion to endothelial surface
    Ewa Stachowska
    Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland
    Int J Food Sci Nutr 63:30-5. 2012
  2. ncbi request reprint Conjugated linoleic acids can change phagocytosis of human monocytes/macrophages by reduction in Cox-2 expression
    Ewa Stachowska
    Department of Biochemistry, Pomeranian Medical University, Szczecin, Poland
    Lipids 42:707-16. 2007
  3. ncbi request reprint Exchange of unsaturated fatty acids between adipose tissue and atherosclerotic plaque studied with artificial neural networks
    E Stachowska
    Department of Biochemistry and Chemistry, Pomeranian Medical University, Al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    Prostaglandins Leukot Essent Fatty Acids 70:59-66. 2004
  4. ncbi request reprint Effect of conjugated linoleic acids on the activity and mRNA expression of 5- and 15-lipoxygenases in human macrophages
    Ewa Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    J Agric Food Chem 55:5335-42. 2007
  5. ncbi request reprint Dietary trans fatty acids and composition of human atheromatous plaques
    Ewa Stachowska
    Dept of Biochemistry and Chemistry, Pomeranian Medical University, Al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    Eur J Nutr 43:313-8. 2004
  6. ncbi request reprint Elements of Mediterranean diet improve oxidative status in blood of kidney graft recipients
    Ewa Stachowska
    Department of Biochemistry and Chemistry, Pomeranian Medical University, Szczecin, Poland
    Br J Nutr 93:345-52. 2005
  7. ncbi request reprint Prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) synthesis is regulated by conjugated linoleic acids (CLA) in human macrophages
    E Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, ul Zolnierska 48, Szczecin, Poland
    J Physiol Pharmacol 60:77-85. 2009
  8. ncbi request reprint Conjugated linoleic acids regulate triacylglycerol and cholesterol concentrations in macrophages/foam cells by the modulation of CD36 expression
    Ewa Stachowska
    Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland
    Acta Biochim Pol 57:379-84. 2010
  9. ncbi request reprint The use of neural networks in evaluation of the direction and dynamics of changes in lipid parameters in kidney transplant patients on the Mediterranean diet
    Ewa Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    J Ren Nutr 16:150-9. 2006
  10. doi request reprint Conjugated linoleic acid increases intracellular ROS synthesis and oxygenation of arachidonic acid in macrophages
    Ewa Stachowska
    Laboratory of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    Nutrition 24:187-99. 2008

Detail Information

Publications26

  1. doi request reprint Conjugated linoleic acid isomers may diminish human macrophages adhesion to endothelial surface
    Ewa Stachowska
    Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland
    Int J Food Sci Nutr 63:30-5. 2012
    ..These mechanisms may contribute to the potent anti-atherosclerotic effects of CLA in vivo...
  2. ncbi request reprint Conjugated linoleic acids can change phagocytosis of human monocytes/macrophages by reduction in Cox-2 expression
    Ewa Stachowska
    Department of Biochemistry, Pomeranian Medical University, Szczecin, Poland
    Lipids 42:707-16. 2007
    ..The inhibition of PGE2 synthesis (by CLA treatment) enhanced the phagocytosis process in macrophages...
  3. ncbi request reprint Exchange of unsaturated fatty acids between adipose tissue and atherosclerotic plaque studied with artificial neural networks
    E Stachowska
    Department of Biochemistry and Chemistry, Pomeranian Medical University, Al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    Prostaglandins Leukot Essent Fatty Acids 70:59-66. 2004
    ....
  4. ncbi request reprint Effect of conjugated linoleic acids on the activity and mRNA expression of 5- and 15-lipoxygenases in human macrophages
    Ewa Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    J Agric Food Chem 55:5335-42. 2007
    ..Linoleic acid induced 15-LO-1 expression (2.6 times, p < 0.05). CLAs may perform the function of an inhibitor of lipoxygenase 15-LO-1 activity in macrophages...
  5. ncbi request reprint Dietary trans fatty acids and composition of human atheromatous plaques
    Ewa Stachowska
    Dept of Biochemistry and Chemistry, Pomeranian Medical University, Al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    Eur J Nutr 43:313-8. 2004
    ..Apparently, the presence of TFA in atheromatous plaques is the result of processes taking place during plaque formation and maturation...
  6. ncbi request reprint Elements of Mediterranean diet improve oxidative status in blood of kidney graft recipients
    Ewa Stachowska
    Department of Biochemistry and Chemistry, Pomeranian Medical University, Szczecin, Poland
    Br J Nutr 93:345-52. 2005
    ..MD appears to protect the erythrocytes against the action of free radicals, as reflected in the modified activities of some enzymes regulating the oxidative status of these blood cells...
  7. ncbi request reprint Prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) synthesis is regulated by conjugated linoleic acids (CLA) in human macrophages
    E Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, ul Zolnierska 48, Szczecin, Poland
    J Physiol Pharmacol 60:77-85. 2009
    ..COX-1 inhibition was resulting from competition of CLA and linoleic acid with arachidonic acid...
  8. ncbi request reprint Conjugated linoleic acids regulate triacylglycerol and cholesterol concentrations in macrophages/foam cells by the modulation of CD36 expression
    Ewa Stachowska
    Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland
    Acta Biochim Pol 57:379-84. 2010
    ..Also in human adipocytes, trans-10,cis-12 CLA causes cell delipidation by reduction of PPAR receptor expression. We propose a similar mechanism for human macrophages/foam cells...
  9. ncbi request reprint The use of neural networks in evaluation of the direction and dynamics of changes in lipid parameters in kidney transplant patients on the Mediterranean diet
    Ewa Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    J Ren Nutr 16:150-9. 2006
    ..The objective of the study was to assess whether neural networks can be a tool useful in the evaluation of the effect of the Mediterranean diet (MD) on the direction and dynamics of selected parameters...
  10. doi request reprint Conjugated linoleic acid increases intracellular ROS synthesis and oxygenation of arachidonic acid in macrophages
    Ewa Stachowska
    Laboratory of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    Nutrition 24:187-99. 2008
    ..The objective of this study was to determine whether CLA can lead to an increase in oxidative stress and to isoprostane synthesis in macrophages...
  11. doi request reprint Comparative effects of conjugated linoleic acid (CLA) and linoleic acid (LA) on the oxidoreduction status in THP-1 macrophages
    Marta Rybicka
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    J Agric Food Chem 59:4095-103. 2011
    ..Only trans-10,cis-12 significantly influenced mRNA for SOD-2 expression. The CLAs activate processes of the ROS formation in macrophages. Adverse metabolic effects of each isomer action were observed...
  12. ncbi request reprint Inhibition of phospholipase A(2) activity by conjugated linoleic acids in human macrophages
    Ewa Stachowska
    Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Al Powstancow Wlkp 72, 70 111 Szczecin, Poland
    Eur J Nutr 46:28-33. 2007
    ..The consequence of this effect may be reduction of releasing the arachidonic acid (AA) from the cellular membranes of macrophages...
  13. ncbi request reprint Simple dietary interventions reduce the risk factors of atherosclerosis in renal graft recipients
    Ewa Stachowska
    Department of Biochemistry and Chemistry, Transplantology, and Internal Medicine, Pomeranian Medical University, Szczecin, Poland
    J Ren Nutr 15:291-7. 2005
  14. ncbi request reprint Does oxidative stress affect the activity of the sodium-proton exchanger?
    Joanna Bober
    Zakład Chemii Medycznej, Pomorskiego Uniwersytetu Medycznego w Szczecinie, Al Powstancow Wlkp 72, 70 111 Szczecin
    Ann Acad Med Stetin 56:5-12. 2010
    ..Studies on NHE in CRF produced results that are discrepant and difficult to interpret. The aim of this study was to demonstrate that oxidative stress had an effect on the activity of NHE...
  15. ncbi request reprint Oxidative stress modulates the organization of erythrocyte membrane cytoskeleton
    Maria Olszewska
    Department of Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    Postepy Hig Med Dosw (Online) 66:534-42. 2012
    ..In available literature there are no reports regarding the changes in protein contents of erythrocyte cytoskeleton exposed to t-butyl hydroperoxide in relation to glucose presence in incubation medium...
  16. ncbi request reprint Influence of glucose in the dialysate on the activity of erythrocyte-glutathione-peroxidase and blood selenium concentration in hemodialyzed patients
    Joanna Bober
    Department of Medical Chemistry, Pomeranian Medical University, Szczecin, Poland
    Arch Med Res 38:330-6. 2007
    ..The aim of the study was to show the influence of glucose in the dialysate on the intensity of oxidative stress, activity of glutathione peroxidase (GSHPx) and concentration of selenium in patients undergoing regular hemodialysis...
  17. ncbi request reprint Isomers of trans fatty acids modify the activity of platelet 12-P lipoxygenase and cyclooxygenase/thromboxane synthase
    Ewa Stachowska
    Department of Biochemistry and Chemistry, Pomeranian Medical University, Szczecin, Poland
    Nutrition 20:570-1. 2004
    ..The aim of this work was to determine the influence of TFA on the aforementioned enzymes: lipoxygenase and cyclooxygenase/thromboxane synthase...
  18. doi request reprint Conjugated linoleic acid regulates phosphorylation of PPARγ by modulation of ERK 1/2 and p38 signaling in human macrophages/fatty acid-laden macrophages
    Ewa Stachowska
    Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland
    J Agric Food Chem 59:11846-52. 2011
    ..In human adipocytes, cis-9,trans-11 C 18:2 raised the activation of PPAR and several of its downstream target genes. We suggest that a similar process may also occur in human macrophages...
  19. doi request reprint Enhanced matrix-degrading proteolytic activity within the thin thrombus-covered wall of human abdominal aortic aneurysms
    Ireneusz Wiernicki
    Department of Vascular Surgery and Angiology, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70 111 Szczecin, Poland
    Atherosclerosis 212:161-5. 2010
    ..In the present study the hypothesis that thin thrombus is associated with enhanced proteolytic activity within human AAA wall was investigated...
  20. ncbi request reprint Shell of snail Helix aspersa maxima (Helicidae) as a protection of bioaccumulation toxic sodium fluoride in soft tissue
    Monika Ewa Rać
    Department of Biochemistry, Pomeranian Medical University, Powstańiców Wielkopolskich 72, 70 111 Szczecin, Poland
    Folia Biol (Krakow) 53:235-8. 2005
    ..In contrast, levels in the shell rose significantly with the concentration of fluoride and can be used in biomonitoring of sodium fluoride pollution...
  21. doi request reprint Lipidic last breath of life in patients with alcoholic liver disease
    Joanna Raszeja-Wyszomirska
    Liver Unit, Pomeranian Medical University, Szczecin, Poland
    Prostaglandins Other Lipid Mediat 99:51-6. 2012
    ..LOXs expression and peroxidation of polyunsaturated fatty acids by free radical-propagated chemical oxidation may be contributing factors in liver necroinflammatory injury in ALD...
  22. doi request reprint Effect of riboflavin supply on student body's provision in north-western Poland with riboflavin measured by activity of glutathione reductase considering daily intake of other nutrients
    Małgorzata Szczuko
    Department of Biochemistry and Human Nutrition, Pomeranian Medical University, Szczecin, Poland
    Int J Food Sci Nutr 62:431-8. 2011
    ..43 mg and 1.8 mg in the female and male groups, respectively. Women with biochemical riboflavin deficiency consumed significantly less of all the analyzed nutrients in comparison with the people without riboflavin deficiency...
  23. ncbi request reprint [Selenium and the activities of cyclooxygenase and lipoxygenase in cells involved in atherogenesis]
    Katarzyna Serwatka
    Katedra i Zakład Biochemii i Chemii Pomorskiej Akademii Medycznej al Powstańców Wlkp 72, Szczecin
    Ann Acad Med Stetin 51:65-8. 2005
    ..This paper presents the properties of selenium, its content in food, and health effects of Se deficiency...
  24. ncbi request reprint [Atherogenic trans isomers of fatty acids in some food products]
    Ewa Stachowska
    Zakład Biochemii, Katedra Biochemii i Chemii Medycznej Pomorskiej Akademii Medycznej al Powstańców Wlkp 72, 71 111 Szczecin
    Ann Acad Med Stetin 52:13-6; discussion 16-7. 2006
    ..Considering the potentially atherogenic properties of TFA, this work was undertaken to determine the content of the principal monounsaturated TFA in some food products ubiquitous on the market, i.e. margarines and snacks...
  25. ncbi request reprint Is conjugated linoleic acid (CLA) a protective factor in atherosclerosis? Study with the use of neural networks
    Ewa Stachowska
    Katedra i Zakład Biochemii i Chemii Medycznej Pomorskiej Akademii Medycznej al Powstancow Wlkp 72, Szczecin
    Ann Acad Med Stetin 51:27-32. 2005
    ..Cooked meat and milk are among the richest dietary sources of CLA. Recently, much attention has been devoted to CLA due to its anti-cancer, anti-atherogenic, and anti-diabetic properties...
  26. ncbi request reprint [The erythrocyte sodium-proton exchanger activity in patient with primary hypertension]
    Joanna Bober
    Zakład Biochemii i Chemii Pomorskiej AM w Szczecinie
    Pol Arch Med Wewn 108:619-24. 2002
    ..2 +/- 2.6 mmol/L RBC/h) p = 0.05. A bimodal distribution of NHE activity in NTP group was observed. There was no correlation between NHE activity and BMI, MAP, SBP, DBP, age or positive family history of hypertension in NTP or K groups...