Research Topics
Genomes and GenesSpecies | Aldona KasprzakSummaryAffiliation: University of Medical Sciences Country: Poland Publications
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Detail Information
Publications
The insulin-like growth factor (IGF) signaling axis and hepatitis C virus-associated carcinogenesis (review)Aldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, 60 781 Poznan, Poland
Int J Oncol 41:1919-31. 2012..Manifestation of various mRNA transcripts and IGF-1 proteins and their potential involvement in carcinogenesis are also discussed...
Differential expression of IGF-1 mRNA isoforms in colorectal carcinoma and normal colon tissueAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
Int J Oncol 42:305-16. 2013....
Role of high endothelial postcapillary venules and selected adhesion molecules in periodontal diseases: a reviewA Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
J Periodontal Res 48:1-21. 2013....
Expression of angiogenesis-stimulating factors (VEGF, CD31, CD105) and angiogenetic index in gingivae of patients with chronic periodontitisAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences in Poznan, Poland
Folia Histochem Cytobiol 50:554-64. 2012..The increased CD105/CD31 and VEGF/CD31 ratios in gingiva confirms an augmented proliferative fraction of the endothelium in gingiva with CP...
Intracellular expression of the proliferative marker Ki-67 and viral proteins (NS3, NS5A and C) in chronic, long lasting hepatitis C virus (HCV) infectionAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan
Folia Histochem Cytobiol 45:357-66. 2007....
p53 immunocytochemistry and TP53 gene mutations in patients with chronic hepatitis C virus (HCV) infectionAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Histochem Cytobiol 47:35-42. 2009..A negative correlation was disclosed between cellular expression of p53 and duration time of infection. In conclusions, genetic changes in TP53 can be detected also in non-neoplastic lesions linked to chronic HCV infection...
p21/Wafl/Cipl cellular expression in chronic long-lasting hepatitis C: correlation with HCV proteins (C, NS3, NS5A), other cell-cycle related proteins and selected clinical dataAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Histochem Cytobiol 47:385-94. 2009..Nevertheless, the studies indicate that neither expression of p21 protein nor that of viral NS3 protein can serve as a marker of progression of CH-C to HCC in vivo...
Tissue expression of interleukin 2 (IL-2) and IL-2 receptor (IL-2R(alpha)/CD25) in non-Hodgkin B-cell lymphomas in children: correlations with clinical dataAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
J Pediatr Hematol Oncol 32:462-71. 2010....
Polysaccharides and mucin 5AC (MUC5AC) expression in gallbladder mucosa of young patients with gallstones as evaluated by spatial visualization and quantificationAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Histochem Cytobiol 48:646-57. 2010....
Histological alterations of gallbladder mucosa and selected clinical data in young patients with symptomatic gallstonesAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan
Pol J Pathol 62:41-9. 2011..The results point also to a potential role of local accumulation of eosinophils in gallbladder mucosa in pathogenesis of CH in young patients...
Cytokeratin 8 and 18 tissue expression in gallbladder mucosa of patients with cholelithiasisAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, Poland
Pol J Pathol 62:241-9. 2011..Significantly higher expression of CK18 than that of CK8 in younger patients suggests a different role of CK8 and 18 in lithogenesis in this group...
Interleukin-2 (IL-2) expression in livers of patients with chronic hepatitis C virus (HCV) infectionAldona Kasprzak
Dept Histology and Embryology, University of Medical Sciences, Swicickiego 6, 60 781 Poznan, Poland
Folia Histochem Cytobiol 44:103-10. 2006..Moreover, expression of IL-2 in the infection was examined for the first time at the ultrastructural level. Mitochondrial localization of IL-2 suggests a direct involvement of the cytokine in disturbed function of the organelles...
Epstein-Barr virus (EBV) infection in B-cell non-Hodgkin's lymphomas in children: virus latency and its correlation with CD21 and CD23 moleculesAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Histochem Cytobiol 45:169-79. 2007....
Intracellular localization of NS3 and C proteins in chronic hepatitis CAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
Liver Int 25:896-903. 2005..In the studies advantage was taken of (Strept)avidin-biotin peroxidase complex and ImmunoMax technique...
Expression of cytokines (TNF-alpha, IL-1alpha, and IL-2) in chronic hepatitis C: comparative hybridocytochemical and immunocytochemical study in children and adult patientsAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
J Histochem Cytochem 52:29-38. 2004..The expression is insufficient to terminate the infection and may be linked with the comparably frequent chronic transformation of HCV infection noted in children and adults...
Tissue markers of Epstein-Bar virus (EBV) infection in B-cell non-Hodgkin's lymphomasAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, ul Swiecickiego 6, 60 781 Poznan, Poland
Med Wieku Rozwoj 10:639-48. 2006....
Morphological lesions detected by light and electron microscopies in chronic type B hepatitisAldona Kasprzak
Department of Histology and Embryology, K Marcinkowski University of Medical Sciences, Poznan
Pol J Pathol 53:103-15. 2002..The data permit us to determine precisely the stage of infection and to make appropriate therapeutic decisions...
The expression of selected neuroendocrine markers and of anti-neoplastic cytokines (IL-2 and IL-12) in lung cancersAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Morphol (Warsz) 62:497-9. 2003..The lowered expression of the two cytokines at the time of diagnosis may represent a prognostic factor for survival in SCLC...
Morphological lesions detected by light and electron microscopies in chronic type C hepatitisAldona Kasprzak
Department of Histology and Embryology, K Marcinkowski University of Medical Sciences, Poznan
Pol J Pathol 54:129-42. 2003..The studies using molecular biology techniques should be continued at the electron microscope level...
Selected markers (chromogranin A, neuron-specific enolase, synaptophysin, protein gene product 9.5) in diagnosis and prognosis of neuroendocrine pulmonary tumoursAldona Kasprzak
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
Pol J Pathol 58:23-33. 2007..With increasing frequency, PGP 9.5 is regarded to provide a prognostic marker in diagnosis of non-small cell lung carcinomas rather than of typical neuroendocrine tumours...
Morphological and molecular diagnosis of a fatal form of EBV infectious mononucleosis in a childAldona Kasprzak
Department of Histology and Embryology, Karol Marcinkowski University of Medical Sciences, Poznan
Pol J Pathol 57:117-30. 2006..In our tissue material co-expression of the two proteins (EBNA2+, LMP1+) and EBER has been demonstrated in every organ, in accordance to the latency III pattern described by other authors...
The effect of extracellular substance components on the proliferation and expression of hormones in cultured cells of medullary thyroid carcinomasMaciej Zabel
Department of Histology and Embryology, University School of Medicine, Wrocław, Poland
Folia Morphol (Warsz) 63:63-6. 2004..On the other hand, rMTC cells were more markedly manifest on any ECM substrates than that on glass. Alterations in the proliferation were paralleled by changes in the expression of CT and CGRP...
Expression of ghrelin receptor (GHSR-1a) in rat epididymal spermatozoa and the effects of its activationAndrzej Łukaszyk
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
Reprod Biol 12:293-300. 2012....
Tissue expression of cytokines (IL-1alpha, IL-2, IL-6, IL-12, TNF-alpha) in B-cell lymphomas in childrenRafał Spachacz
Department of Histology and Embryology, University of Medical Sciences, Wrocław, Poland
Folia Morphol (Warsz) 62:483-4. 2003..The studies pointed to a decreased production of antitumour cytokines in B-cell lymphomas in children, which might correspond to the progression of the tumour...
The expression of calcitonin, calcitonin gene-related peptide and somatostatin in the thyroids of rats of different agesJolanta Seidel
Chair of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Morphol (Warsz) 62:485-7. 2003..In the case of somatostatin, however, multiple parafollicular cells produced mRNA for the hormone but few cells demonstrated the presence of the corresponding protein...
Immunocytochemical analysis of the tissue location of cytokines (IL-2 and IL-12) in neuroendocrine lung cancerAldona Kasprzak
Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland
Folia Morphol (Warsz) 62:301-3. 2003..Our studies point to a possible role of the two cytokines in the proliferation of lung neuroendocrine carcinomas but more detailed analysis is required on a broader material...
Detecting the replication of the hepatitis B virus using the ImmunoMax technique following treatment with interferon-alpha in children with chronic hepatitisAldona Kasprzak
Department of Histology and Embryology, Medical University of Poznan, Poland
Med Sci Monit 8:PR1-7. 2002..Our study was intended to evaluate HBV expression in liver biopsies taken an average of two years after completion of IFN-a therapy in 10 children with serological markers of persistent HBV infection...
Biological properties of interleukin 2 and its role in pathogenesis of selected diseases--a reviewKarolina Olejniczak
Department of Histology and Embryology, Karol Marcinkowski Medical University, Poznan, Poland
Med Sci Monit 14:RA179-89. 2008..Attempts to treat tumors are also discussed, using modified varieties of therapy that use IL-2 itself and/or its receptor...
Immunohistochemical and hybridocytochemical study on ghrelin signalling in the rat seminiferous epitheliumAndrzej Łukaszyk
Department of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland
Folia Histochem Cytobiol 47:415-23. 2009..Immunostaining pattern for GHSR-1a seems to suggest both its participation in the cross-talk among the cells and also process of furnishing gametes with GHSR-1a for its response to ghrelin in seminal plasma or female reproductive tract...
Role of hepatitis C virus proteins (C, NS3, NS5A) in hepatic oncogenesisAldona Kasprzak
Department of Histology and Embryology, Medical University, Poznan, Poland
Hepatol Res 38:1-26. 2008..This work summarizes the information collected thus far in the field of HCV molecular virology and principal intracellular signaling pathways in which HCV oncogenic proteins are involved...
