Research Topics
| Michał KarasekSummaryAffiliation: University of Lodz Country: Poland Publications
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Detail Information
Publications
Serum melatonin circadian profiles in women suffering from cervical cancerMichal Karasek
Department of Electron Microscopy, Polish Mother s Memorial Hospital Research Institute, Medical University of Lodz, Lodz, Poland
J Pineal Res 39:73-6. 2005..The results of the present study indicate that the presence of cervical cancer influences melatonin levels in women. Moreover, stage dependence in reduction of melatonin concentrations has been found...
Decreased melatonin nocturnal concentrations in hemodialyzed patientsMichal Karasek
Department of Neuroendocrinology, Medical University of Lodz, Lodz, Poland
Neuro Endocrinol Lett 26:653-6. 2005..Therefore, the aim of the present study was to determine the circadian melatonin profiles in patients ESRD before and after hemodialysis...
Ultrastructure of the central nervous system: the basicsMichał Karasek
Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
Folia Neuropathol 42:1-9. 2004....
Melatonin in humansM Karasek
Department of Neuroendocrinology, Medical University of Lodz, Poland
J Physiol Pharmacol 57:19-39. 2006..In this survey the basic data on melatonin significance in human physiology and in pathological processes as well as its possible therapeutic significance are reviewed and discussed...
[Hyperprolactinemia: causes, diagnosis, and treatment]Michał Karasek
Department of Neuroendocrinology, Chair of Endocrinology, Medical University, Lodz
Endokrynol Pol 57:656-62. 2006..Surgery should be performed only in the patients resistant or intolerant to these agents, or in patients who refuse long-term therapy...
Increased melatonin concentrations in children with growth hormone deficiencyMichal Karasek
Department of Neuroendocrinology, Medical University of Lodz, Lodz, Poland
J Pineal Res 42:119-24. 2007..On the basis of these data it seems that the assessment of nocturnal melatonin secretion might be a valuable diagnostic tool used for the improvement of the difficult diagnosis of short stature in children...
[Hormones of youth?]Michał Karasek
Zakład Neuroendokrynologii, Katedra Endokrynologii, Uniwersytet Medyczny, Łódź
Endokrynol Pol 58:153-61. 2007..However, some symptoms of the quality of life improvement following administration of dehydroepiandrosterone, melatonin, and growth hormone may suggest that they may promote so called "successful aging"...
Does melatonin play a role in aging processes?M Karasek
Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Czechoslowacka 8 10, Lodz, Poland
J Physiol Pharmacol 58:105-13. 2007..In this survey the basic data on the possible role of melatonin in human aging as well as its possible therapeutic significance are reviewed and discussed...
Circadian pattern of prolactin secretion in children with growth hormone deficiency and congenital organic lesions in the hypothalamic-pituitary regionRenata Stawerska
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother s Memorial Hospital Research Institute of Lodz, Poland
Neuro Endocrinol Lett 28:765-74. 2007..The aim of the study was to assess circadian Prl pattern in children with growth hormone deficiency (GHD) and congenital organic disorders in the hypothalamic-pituitary region (HPR)...
Effects of melatonin and melatonin receptors ligand N-[(4-methoxy-1H-indol-2-yl)methyl]propanamide on murine Colon 38 cancer growth in vitro and in vivoKatarzyna Winczyk
Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Lodz, Poland
Neuro Endocrinol Lett 23:50-4. 2002..CONCLUSION: The obtained data together with our earlier observations suggest that oncostatic effect of MLT depends on acting via both MT(2) and RZR/ROR nuclear receptors..
Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cellsKatarzyna Winczyk
Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
Neuro Endocrinol Lett 27:351-4. 2006..CONCLUSION: The obtained data together with our previous results indicate that nuclear receptors RZR/ROR play an important, although not sufficiently recognized role in the oncostatic action of melatonin...
Melatonin and agingMichal Karasek
Laboratory of Electron Microscopy, Chair of Pathomorphology, Medical University of Lodz, 92 216 Lodz, Czechoslowacka 8 10, Poland
Neuro Endocrinol Lett 23:14-6. 2002..However, the precise role of melatonin in the aging process remains to be determined...
Melatonin circadian rhythm in women with idiopathic hyperprolactinemiaMichal Karasek
Department of Endocrinology an Isotope Therapy, Medical University of Lodz Polish Mother s Memorial Hospital Research Institute, Lodz, Poland
Neuro Endocrinol Lett 25:411-4. 2004..Therefore, the aim of the present study was to evaluate the circadian rhythm of melatonin in female patients suffering from hyperprolactinemia...
Electromagnetic fields and human endocrine systemMichal Karasek
Department of Electron Microscopy, Chair of Pathomorphology, Medical University of Lodz, Poland
ScientificWorldJournal 4:23-8. 2004..Most of the results concentrate on influence of EMF on secretion of melatonin. In this review, the data on the influence of EMF on human endocrine system are briefly presented and discussed...
Expression of melatonin MT(1) and MT(2) receptors, and ROR alpha(1) receptor in transplantable murine Colon 38 cancerMichal Karasek
Laboratory of Electron Microscopy, Chair of Pathology, Medical University of Lodz, Lodz, Poland
Neuro Endocrinol Lett 23:55-60. 2002..Therefore, the aim of the present study was to determine whether the membrane melatonin receptors MT(1) and MT(2) as well as the nuclear receptor RZR/ROR alpha are expressed in Colon 38 cells...
Melatonin and magnetic fieldsMichal Karasek
Laboratory of Electron Microscopy, Chair of Pathomorphology, Medical University of Lodz Poland
Neuro Endocrinol Lett 23:84-7. 2002..In this review the data on the influence of magnetic fields on melatonin synthesis, both in the animals and humans, are briefly presented and discussed...
Circadian serum melatonin profiles in patients suffering from chronic renal failureMichal Karasek
Laboratory of Electron Microscopy, Chair of Pathomorphology, Medical University of Lodz, Lodz, Poland
Neuro Endocrinol Lett 23:97-102. 2002..Moreover, the most melatonin assays were performed during the daytime, and the results are conflicting. Therefore, the aim of the present study was to determine the circadian melatonin profiles in patients with different stages of CRF...
Future of melatonin as a therapeutic agentMichal Karasek
Clinic of Endocrinology, Polish Mother s Memorial Hospital Research Institute, Lodz, Poland
Neuro Endocrinol Lett 23:118-21. 2002..All aspects of the possible therapeutic use of melatonin as well as its safety, dosage, side effects and contraindications are discussed herein based on the round table conference and they are presented in this paper...
Effect of superior cervical ganglionectomy on the ultrastructure of pinealocytes in the Djungarian hamster (Phodopus sungorus): quantitative studyMichal Karasek
Department of Electron Microscopy, Chair of Pathomorphology, Medical University of Lodz, 92 216 Lodz, Czechoslowacka 8 10, Poland
Neuro Endocrinol Lett 23:443-6. 2002..Changes in pineal morphology have been observed in many mammalian species after sympathectomy. Therefore, we decided to investigate the ultrastructure of Djungarian hamster pinealocytes following superior cervical ganglionectomy...
Melatonin inhibits growth of diethylstilbestrol-induced prolactin-secreting pituitary tumor in vitro: possible involvement of nuclear RZR/ROR receptorsMichal Karasek
Department of Electron Microscopy, Chair of Pathomorphology, Medical University of Lodz, Lodz, Poland
J Pineal Res 34:294-6. 2003....
Etiopathogenesis of Graves' diseaseMichal Karasek
Department of Endocrinology and Isotope Therapy, Medical University of Lodz Polish Mother s Memorial Hospital Research Institute, Lodz, Poland
Neuro Endocrinol Lett 24:161-6. 2003..This article discusses current theories, regarding the etiology and pathogenesis of Graves' disease, including possible predisposing factors, autoimmune aspects of Graves' disease, ophthalmopathy, and dermopathy...
Ultrastructure of pinealocytes in mice implanted with Colon 38 adenocarcinomaMichal Karasek
Department of Electron Microscopy, Medical University of Lodz, Poland
Neuro Endocrinol Lett 24:269-73. 2003..However, morphological studies of the pineal gland in animals with experimentally-induced tumors are rare. Therefore, we decided to investigate the ultrastructure of pinealocytes in mice with implanted Colon 38 adenocarcinoma...
Partial growth hormone deficiency (GHD) in children has more similarities to idiopathic short stature than to severe GHDJoanna Smyczynska
Department of Endocrinology and Metabolic Diseases, Polish Mother s Memorial Hospital Research Institute, Łódź
Endokrynol Pol 58:182-7. 2007..The aim of the study was to compare the deficit of height at diagnosis, IGF-I secretion and PAH in children with either decreased (in varying degrees of severity) or normal GH secretion in stimulation tests...
The effects of melatonin, N-acetylserotonin, and 6-hydroxymelatonin on the ultrastructure of the pinealocytes of the Syrian hamster (Mesocricetus auratus)Anna Zielinska
Department of Neuroendocrinology, Medical University of Łódź, Łódź
Endokrynol Pol 57:2-6. 2006..The aim of this study was to examine the effects of melatonin as well as of its precursor (N-acetylserotonin) and metabolite (6-hydroxymelatonin) on the ultrastructure of the pinealocytes of the Syrian hamster...
High repeatability of circadian prolactin rhythm assessment results in childrenRenata Stawerska
Department of Pediatric Endocrinology, Chair of Endocrinology and Metabolic Diseases, Medical University of Lodz, Poland
Neuro Endocrinol Lett 29:889-94. 2008..The aim of the study was to assess the repeatability of that circadian Prl secretion pattern in a group of short children without hormonal disorders...
Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitroKatarzyna Winczyk
Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
Neuro Endocrinol Lett 30:657-62. 2009....
Oncostatic action of melatonin: facts and question marksMarek Pawlikowski
Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Sterling str 3, 91 425 Lodz, Poland
Neuro Endocrinol Lett 23:24-9. 2002..However, the recent data from our and other laboratories suggest also the involvement of RZR/ROR receptors (the putative melatonin nuclear receptors) in both melatonin-induced proliferation inhibition and apoptosis...
Effects of six months melatonin treatment on sleep quality and serum concentrations of estradiol, cortisol, dehydroepiandrosterone sulfate, and somatomedin C in elderly womenMarek Pawlikowski
Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, 91 425 Lodz, Sterling str 3, Poland
Neuro Endocrinol Lett 23:17-9. 2002..Therefore, an open pilot study on the effects of melatonin administration on some sleep parameters, routine hematological and biochemical parameters, and concentrations of hormones was performed in elderly women...
Assessment of insulin-like growth factor-I serum concentration as a screening procedure in diagnosing children with short statureJoanna Smyczynska
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother s Memorial Hospital Research Institute, Lodz, Poland
Neuro Endocrinol Lett 28:274-8. 2007..The goal of the study was an analysis of the relations between GH secretion in stimulating tests and plasma IGF-I concentration...
