Research Topics

Genomes and Genes


Bogna Grygiel-Górniak


Affiliation: University of Medical Sciences
Country: Poland


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    Grygiel Górniak B, Puszczewicz M, Czaplicka E. Susac syndrome--clinical insight and strategies of therapy. Eur Rev Med Pharmacol Sci. 2015;19:1729-35 pubmed
    ..In this review, we have demonstrated the epidemiology and pathology of Susac syndrome with detailed description of clinical signs, diagnostic procedures and therapeutic possibilities. ..
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    Grygiel Górniak B, Puszczewicz M. Granulomatosis with polyangiitis in pregnancy - clinical implications and treatment possibilities. Eur Rev Med Pharmacol Sci. 2015;19:2331-5 pubmed
    ..Thus, the approach to care for pregnant women with GPA is interdisciplinary, and firmly places the rheumatologist, gynecologist, pulmonologist, otorhinolaryngologist and nephrologist on the management team. ..
  3. Grygiel Gorniak B, Kaczmarek E, Mosor M, Przysławski J, Bogacz A. Genetic Background, Adipocytokines, and Metabolic Disorders in Postmenopausal Overweight and Obese Women. Biochem Genet. 2016;54:636-52 pubmed publisher
    ..045). In postmenopausal women, metabolic parameters are mainly determined by the distribution of body fat, but Ala12/X polymorphism may increase the metabolic disorders and this effect can be enhanced by the T1431 allele. ..
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    Grygiel Górniak B, Puszczewicz M, Czaplicka E. Neurological, otolaryngological and ophthalmological implications of Susac syndrome - a case report. Eur Rev Med Pharmacol Sci. 2016;20:3073-7 pubmed
    ..Methylprednisolone with acetylsalicylic acid and intravenous immunoglobulin (IVIG) were implemented with a positive outcome (clinical and audiometric improvement). ..
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    Grygiel Gorniak B, Mosor M, Marcinkowska J, Przyslawski J, Nowak J. Impact of the PPAR gamma-2 gene polymorphisms on the metabolic state of postmenopausal women. J Biosci. 2016;41:427-37 pubmed
    ..In conclusion, C1431T polymorphism seems to have a more essential influence on anthropometric and biochemical parameters than is the case with Pro12Ala polymorphism. ..
  6. Grygiel Gorniak B, Kaczmarek E, Mosor M, Przysławski J, Nowak J. Gene-diet-related factors of hyperglycaemia in postmenopausal women. J Appl Genet. 2018;59:169-177 pubmed publisher
    ..However, not only the genetic background but also the dietary habits (intake of fat, carbohydrates and B vitamins) determine the risk of hyperglycaemia. ..
  7. Grygiel Gorniak B. Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications--a review. Nutr J. 2014;13:17 pubmed publisher
    ..A current understanding of the effects of PPARs, their molecular mechanisms and the role of these receptors in nutrition and therapeutic treatment are delineated in this paper. ..
  8. Grygiel Górniak B, Mosor M, Marcinkowska J, Przysławski J, Nowak J. Uric acid and obesity-related phenotypes in postmenopausal women. Mol Cell Biochem. 2018;443:111-119 pubmed publisher
    ..A better management of metabolic factors could help prevent further increase in UA levels. ..
  9. Grygiel Górniak B, Kaczmarek E, Mosor M, Przysławski J, Nowak J. The Gene-Diet Associations in Postmenopausal Women with Newly Diagnosed Dyslipidemia. J Nutr Health Aging. 2017;21:1031-1037 pubmed publisher
    ..Both nutritional and genetic factors are related to lipid profile. The identification of gene-diet associations is likely to provide useful information about the etiology of postmenopausal dyslipidemia and help in effective treatment. ..

More Information


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    Grygiel Górniak B, Puszczewicz M. A review on irisin, a new protagonist that mediates muscle-adipose-bone-neuron connectivity. Eur Rev Med Pharmacol Sci. 2017;21:4687-4693 pubmed
    ..However, the existence of this protein and its role in humans is a matter of debate. This study presents irisin as a new champion of the molecule, which could be considered as the messenger in the muscle-fat-bone-brain axis. ..