M Gajecka

Summary

Affiliation: University of Warmia and Mazury
Country: Poland

Publications

  1. ncbi request reprint The biotransformation of chosen mycotoxins
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 12:293-303. 2009
  2. pmc The expression of type-1 and type-2 nitric oxide synthase in selected tissues of the gastrointestinal tract during mixed mycotoxicosis
    Magdalena Gajęcka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul Oczapowskiego 13 29, Olsztyn 10 718, Poland
    Toxins (Basel) 5:2281-92. 2013
  3. doi request reprint The effect of low doses of zearalenone and its metabolites on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
    Magdalena Gajęcka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul Oczapowskiego 13 29, 10 718 Olsztyn, Poland Electronic address
    Toxicon 76:260-9. 2013
  4. ncbi request reprint The effects of experimental administration of low doses of zearalenone on the histology of ovaries in pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13 29, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:313-22. 2013
  5. ncbi request reprint The effect of experimental low zearalenone intoxication on ovarian follicles in pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:45-54. 2013
  6. ncbi request reprint Immunocytochemical expression of 3beta- and 17beta-hydroxysteroid dehydrogenase in bitch ovaries exposed to low doses of zearalenone
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:55-62. 2013
  7. ncbi request reprint The effect of low-dose experimental zearalenone intoxication on the immunoexpression of estrogen receptors in the ovaries of pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 15:685-91. 2012
  8. ncbi request reprint The low doses effect of experimental zearalenone (ZEN) intoxication on the presence of Ca2+ in selected ovarian cells from pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 15:711-20. 2012
  9. doi request reprint The effect of experimental, long-term exposure to low-dose zearalenone mycotoxicosis on the histological condition of ovaries in sexually immature gilts
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland
    Theriogenology 75:1085-94. 2011
  10. ncbi request reprint Histopathological examination of ovaries in bitches after experimental zearalenone mycotoxicosis
    M Gajecka
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Protection of Public Health, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 11:363-6. 2008

Collaborators

Detail Information

Publications29

  1. ncbi request reprint The biotransformation of chosen mycotoxins
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 12:293-303. 2009
    ..It can be concluded from research studies that our knowledge of mycotoxin biotransformation is scarce...
  2. pmc The expression of type-1 and type-2 nitric oxide synthase in selected tissues of the gastrointestinal tract during mixed mycotoxicosis
    Magdalena Gajęcka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul Oczapowskiego 13 29, Olsztyn 10 718, Poland
    Toxins (Basel) 5:2281-92. 2013
    ..Our results suggest that the presence of low mycotoxin doses in feed slows down the mRNA expression of both nitric oxide synthase isomers, which probably lowers the concentrations of nitric oxide, a common precursor of inflammation. ..
  3. doi request reprint The effect of low doses of zearalenone and its metabolites on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
    Magdalena Gajęcka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul Oczapowskiego 13 29, 10 718 Olsztyn, Poland Electronic address
    Toxicon 76:260-9. 2013
    ..Our results indicate that NOAEL doses have stimulating/adaptive effects, whereas doses above NOAEL values suggest that even very low zearalenone doses can act as endocrine disruptors with regard to progesterone and 17β-estradiol...
  4. ncbi request reprint The effects of experimental administration of low doses of zearalenone on the histology of ovaries in pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13 29, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:313-22. 2013
    ....
  5. ncbi request reprint The effect of experimental low zearalenone intoxication on ovarian follicles in pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:45-54. 2013
    ..The changes observed were particularly advanced in EII animals, which were administered a higher dose of ZEN...
  6. ncbi request reprint Immunocytochemical expression of 3beta- and 17beta-hydroxysteroid dehydrogenase in bitch ovaries exposed to low doses of zearalenone
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:55-62. 2013
    ..The results revealed that changes in the immunoexpression of the above enzymes were inversely proportional to the applied dose of ZEN substrate...
  7. ncbi request reprint The effect of low-dose experimental zearalenone intoxication on the immunoexpression of estrogen receptors in the ovaries of pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 15:685-91. 2012
    ....
  8. ncbi request reprint The low doses effect of experimental zearalenone (ZEN) intoxication on the presence of Ca2+ in selected ovarian cells from pre-pubertal bitches
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 15:711-20. 2012
    ....
  9. doi request reprint The effect of experimental, long-term exposure to low-dose zearalenone mycotoxicosis on the histological condition of ovaries in sexually immature gilts
    M Gajecka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland
    Theriogenology 75:1085-94. 2011
    ....
  10. ncbi request reprint Histopathological examination of ovaries in bitches after experimental zearalenone mycotoxicosis
    M Gajecka
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Protection of Public Health, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 11:363-6. 2008
    ..Furthermore, in ovarian cells and tissues of both experimental groups, no reaction for PCNA antigen was observed. In conclusion, zearalenone and its metabolites exerts unfavorable effects on the morphology of ovaries in bitches...
  11. ncbi request reprint Ultrastructural changes of ovarian follicle and corpus luteum after experimental zearalenone mycotoxicosis in bitch
    M Gajecka
    Division of Veterinary Prophylaxis and Feed Hygiene, aculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10 718 Olsztyn, Poland
    Pol J Vet Sci 11:327-37. 2008
    ..It seems therefore that in bitches and other monogastric animals, intoxications induced by this mycotoxin causes ultrastructural changes in granular cells of ovarian follicles...
  12. ncbi request reprint Histopathological and immunohistochemical examinations, and changes in proliferation activity of the uterus in bitches following zearalenon micotoxicosis
    M Gajecka
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Protection of Public Health, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 10:143-51. 2007
    ..e. degeneration, atrophy, edema, and extravasation within the endometrium and myometrium) develops. This research proves that zearalenon ingested by bitches may lead to dysfunction of the uterus and cause disruption of its structures...
  13. doi request reprint The effect of experimental long-term exposure to low-dose zearalenone on uterine histology in sexually immature gilts
    Magadalena Gajęcka
    Department of Veterinary Prevention and Feed Hygiene, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Exp Toxicol Pathol 64:537-42. 2012
    ..Such effects probably results from synergic interaction that produce hyperestrogenism and lead to excessive estrogenic stimulation...
  14. ncbi request reprint Zearalenone applied per os provides adverse effects in structure of chosen parts of bitch reproductive system
    M Gajecka
    Division of Veterinary Prevention and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Poland
    Pol J Vet Sci 7:59-66. 2004
    ..They could also indicate a follicular phase of the oestrus cycle in bitch. However, it did not take place...
  15. ncbi request reprint Level of zearalenone in blood serum and lesions in ovarian follicles of sexually immature gilts in the course of zearalenone micotoxicosis
    W Zwierzchowski
    Division of Veterinary Prevention and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 8:209-18. 2005
    ..This probably occurred through the activation of on apoptosis-like process of the granulosa cells with simultaneous manifestation of estrus without standing reflex...
  16. ncbi request reprint Metabolic profile of pigs fed feed containing zearalenone destructor
    M Polak
    Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 7:187-91. 2004
    ..It can be suggested that it is a safe feed supplement pigs in prevention of zearalenone micotoxicosis...
  17. ncbi request reprint Histological estimation of the small intestine wall after administration of feed containing deoxynivalenol, T-2 toxin and zearalenone in the pig
    K Obremski
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 11:339-45. 2008
    ..However, low concentrations of DON, T-2 and ZEA probably influence enterocytes metabolism and evoke inflammation of the mucous membrane of the small intestine...
  18. ncbi request reprint Influence of zearalenone micotoxicosis on selected immunological, haematological and biochemical indexes of blood plasma in bitches
    M Gajecka
    Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego St 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 7:175-80. 2004
    ..It can be indirectly suggested that the inhibition of the humoral reaction of the organism, stimulation of detoxification effect in the liver and decreased cellular answer took place...
  19. ncbi request reprint The impact of zearalenone on the level of the selected estrogens in blood serum of sexually immature gilts
    W Zwierzchowski
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 9:247-52. 2006
    ..The presents study revealed that zearalenone applied per os at LOEL dose causes the incidence of apparent sexual readiness (without standing reflex) in sexually immature gilts with the somatically immature reproductive system...
  20. ncbi request reprint Preliminary results of monitoring research on zearalenone presence in blood of women with neoplastic lesions in reproductive system
    M Gajecki
    Division of Veterinary Prevention and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego St 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 7:153-6. 2004
    ..51% of the examined women. In 60% of the patients with the confirmed presence of the xenobiotic it was noted in the lowest concentrations. These patients had neoplastic lesions of Carcinoma corpus uteri type...
  21. ncbi request reprint Influence of zearalenone on reproductive system cell proliferation in gilts
    K Obremski
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 6:239-45. 2003
    ..Intensified cell proliferation, which was expressed with the growth of PCNA index, was observed in uterus and oviduct...
  22. ncbi request reprint The evaluation of the efficacy of sodium carbonate as zearalenone destructor in feeding stuffs
    M Polak
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Protection of Public Health, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 12:103-11. 2009
    ..graminearum isolates). These doses were found to be effective in in vitro studies. The addition of 2% sodium carbonate gave the best results in reducing the phytoestrogen in the feed...
  23. ncbi request reprint The effect of T-2 toxin on percentages of CD4+, CD8+, CD4+ CD8+ and CD21+ lymphocytes, and mRNA expression levels of selected cytokines in porcine ileal Peyer's patches
    K Obremski
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 16:341-9. 2013
    ..06 and p = 0.00, respectively). On days 14 and 28, the percentages of CD4+ and CD8+ T lymphocytes were lower in the experimental animals than in the control group, and the drop reported on day 28 was statistically significant (p = 0.03)...
  24. ncbi request reprint The effect of exogenous proteases on selected hematological and serum biochemical parameters in boars
    Ł Zielonka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13 29, 10 718 Olsztyn, Poland
    Pol J Vet Sci 13:151-6. 2010
    ..The statistically different hematological and serum biochemical parameters, while within normal limits, point to an early stage of microcytic anemia and heightened agitation that could be the result of intensified nitrogen metabolism...
  25. ncbi request reprint Factors determining sensitivity of prepubertal gilts to hormonal influence of zearalenone
    E Jakimiuk
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 12:149-58. 2009
    ....
  26. ncbi request reprint Morphology and ultrastructure of small intestine mucosa in gilts with zearalenone mycotoxicosis
    K Obremski
    Division of Veterinary Prophylaxis and Feed Hygiene, Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Poland
    Pol J Vet Sci 8:301-7. 2005
    ....
  27. ncbi request reprint Influence of low doses of deoxynivalenol on histopathology of selected organs of pigs
    Ł Zielonka
    Division of Veterinary Prevention and Feed Hygiene, Department of Veterinary Public Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, 10 718 Olsztyn, Poland
    Pol J Vet Sci 12:89-95. 2009
    ....
  28. ncbi request reprint Preliminary evaluation of influence of zearalenone on cocultures of granulosa and internal theca cells of ovarian follicles in bitches in in vitro culture
    E Skorska-Wyszyńska
    Department of Veterinary Health Protection, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, ul Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 7:305-9. 2004
    ..Numerous vacuoles in the cytoplasm of the granulosa cells were noted in the culture with the addition of 25.0 ng/ml of ZEA. Preliminary investigations suggest negative effect of ZEA on the granulosa cells in bitches in vitro...
  29. ncbi request reprint Evaluation of the degree of pancreas activity in piglets from sows fed enzymatic stimulating complex
    Ł Zielonka
    Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10 718 Olsztyn, Poland
    Pol J Vet Sci 12:539-47. 2009
    ..The findings indicate a slow process of granule release, which may be the result of overproduction, lower requirements for enzymes contained in the granules, or both...