L Tylicki

Summary

Country: Poland

Publications

  1. ncbi request reprint Short-term effects of angiotensin II receptor blockade in patients with primary glomerulonephritis: pilot study
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    J Ren Nutr 12:122-5. 2002
  2. ncbi request reprint Renal protective effects of the renin-angiotensin-aldosterone system blockade: from evidence-based approach to perspectives
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Kidney Blood Press Res 28:230-42. 2005
  3. ncbi request reprint Blood coagulation unaffected by ozonated autohemotherapy in patients on maintenance hemodialysis
    Bogdan Biedunkiewicz
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Arch Med Res 37:1034-7. 2006
  4. ncbi request reprint Smoking as a risk factor for renal injury in essential hypertension
    Leszek Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    Nephron Clin Pract 103:c121-8. 2006
  5. ncbi request reprint Multifactoral analysis of determinators for renal injury in essential hypertension
    L Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    J Hum Hypertens 20:93-5. 2006
  6. doi request reprint Dual blockade of the renin-angiotensin-aldosterone system with high-dose angiotensin-converting enzyme inhibitor for nephroprotection: an open, controlled, randomized study
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Scand J Urol Nephrol 42:381-8. 2008
  7. ncbi request reprint Randomized placebo-controlled study on the effects of losartan and carvedilol on albuminuria in renal transplant recipients
    Leszek Tylicki
    Department of Nephrology, Transplantology, and Internal Medicine, Medical University of Gdansk, Poland
    Transplantation 81:52-6. 2006
  8. ncbi request reprint Platelet function unaffected by ozonated autohaemotherapy in chronically haemodialysed patients
    Leszek Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Blood Coagul Fibrinolysis 15:619-22. 2004
  9. ncbi request reprint Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine Medical University of Gdansk, Gdansk, Poland
    Am J Hypertens 18:1442-8. 2005
  10. pmc No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, ul Debinki 7, 80 211 Gdansk, Poland
    Mediators Inflamm 13:377-80. 2004

Detail Information

Publications41

  1. ncbi request reprint Short-term effects of angiotensin II receptor blockade in patients with primary glomerulonephritis: pilot study
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    J Ren Nutr 12:122-5. 2002
    ..The aim of the present study was to investigate renal and metabolic effects of specific AT-1 receptor blocker-losartan in patients with primary glomerulonephritis...
  2. ncbi request reprint Renal protective effects of the renin-angiotensin-aldosterone system blockade: from evidence-based approach to perspectives
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Kidney Blood Press Res 28:230-42. 2005
    ....
  3. ncbi request reprint Blood coagulation unaffected by ozonated autohemotherapy in patients on maintenance hemodialysis
    Bogdan Biedunkiewicz
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Arch Med Res 37:1034-7. 2006
    ..Thrombotic complications are the major cause of morbidity and mortality in hemodialyzed patients. Effects of O(3)-AHT on blood coagulation were evaluated in 11 hemodialyzed patients affected by PAOD...
  4. ncbi request reprint Smoking as a risk factor for renal injury in essential hypertension
    Leszek Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    Nephron Clin Pract 103:c121-8. 2006
    ..The dependence of kidney lesions on the 'extent' of smoking was determined as well...
  5. ncbi request reprint Multifactoral analysis of determinators for renal injury in essential hypertension
    L Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    J Hum Hypertens 20:93-5. 2006
  6. doi request reprint Dual blockade of the renin-angiotensin-aldosterone system with high-dose angiotensin-converting enzyme inhibitor for nephroprotection: an open, controlled, randomized study
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Scand J Urol Nephrol 42:381-8. 2008
    ..To improve renal outcome one may consider using increased dosages of ACEI above those usually recommended for hypertension...
  7. ncbi request reprint Randomized placebo-controlled study on the effects of losartan and carvedilol on albuminuria in renal transplant recipients
    Leszek Tylicki
    Department of Nephrology, Transplantology, and Internal Medicine, Medical University of Gdansk, Poland
    Transplantation 81:52-6. 2006
    ..The safety of this therapy was also evaluated...
  8. ncbi request reprint Platelet function unaffected by ozonated autohaemotherapy in chronically haemodialysed patients
    Leszek Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Blood Coagul Fibrinolysis 15:619-22. 2004
    ..In the present study, the influence of ozonated autohaemotherapy (O3-AHT) on the platelet function was evaluated in chronically haemodialysed patients with peripheral arterial disease...
  9. ncbi request reprint Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine Medical University of Gdansk, Gdansk, Poland
    Am J Hypertens 18:1442-8. 2005
    ....
  10. pmc No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, ul Debinki 7, 80 211 Gdansk, Poland
    Mediators Inflamm 13:377-80. 2004
    ..Ozone as a strong oxidant may induce an inflammatory response...
  11. ncbi request reprint Randomized, controlled study of the effects of losartan versus enalapril in small doses on proteinuria and tubular injury in primary glomerulonephritis
    Leszek Tylicki
    Department of Nephrology, Medical University of Gdansk, 80 211 Gdansk, Poland
    Med Sci Monit 11:PI31-7. 2005
    ..The aim of this study was to evaluate the effects of low-dose (25 mg) losartan on proteinuria and tubular injury extent...
  12. doi request reprint Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial
    Leszek Tylicki
    Department of Nephrology Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Am J Kidney Dis 52:486-93. 2008
    ....
  13. ncbi request reprint Renal allograft protection with angiotensin II type 1 receptor antagonists
    L Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Am J Transplant 7:243-8. 2007
    ..Urine excretion of TGF-beta1 and PIIINP was significantly lower after losartan. In conclusion, losartan reduces urine excretion of proteins associated with tubular damage and graft fibrosis...
  14. ncbi request reprint Beneficial clinical effects of ozonated autohemotherapy in chronically dialysed patients with atherosclerotic ischemia of the lower limbs--pilot study
    L Tylicki
    Department of Nephrology, Medical University, , Poland
    Int J Artif Organs 24:79-82. 2001
    ..It could also be a complement to current treatment, especially in cases where the latter has failed...
  15. ncbi request reprint Natural killer cell activity unaffected by ozonated autohemotherapy in patients with end-stage renal disease on maintenance renal replacement therapy
    B Biedunkiewicz
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Int J Artif Organs 27:766-71. 2004
    ..98 +/- 6.67), and after nine sessions of O3-AHT (18.26 +/- 8.82). In conclusion, our findings showed that O3-AHT in a dose of 50 mg/mL does not have any significant influence on natural killer cell function in hemodialyzed patients...
  16. ncbi request reprint Renoprotective effect of small doses of losartan and enalapril in patients with primary glomerulonephritis. Short-term observation
    Leszek Tylicki
    Department of Nephrology, Medical University of Gdansk, Poland
    Am J Nephrol 22:356-62. 2002
    ..However, there is lack of data concerning renoprotective action of very small doses of these drugs...
  17. ncbi request reprint Clinical efficacy of ozonated autohemotherapy in hemodialyzed patients with intermittent claudication: an oxygen-controlled study
    B Biedunkiewicz
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Poland
    Int J Artif Organs 27:29-34. 2004
    ..The aim of this study was to evaluate the influence of ozonated autohemotherapy on walking ability and the subjective clinical experience of hemodialyzed patients with peripheral arterial disease...
  18. ncbi request reprint The effect of N-acetylcysteine on blood pressure and markers of cardiovascular risk in non-diabetic patients with chronic kidney disease: a placebo-controlled, randomized, cross-over study
    Marcin Renke
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Med Sci Monit 16:PI13-8. 2010
    ..Antioxidants, e.g., N-acetylcysteine (NAC), have been suggested as a promising medicament in this field...
  19. ncbi request reprint Hypertensive nephropathy - an increasing clinical problem
    B Rutkowski
    Department of Nephrology, Medical University, Gdansk, Poland
    Miner Electrolyte Metab 25:65-8. 1999
    ..40), MAP (r = 0.47) and PUAA (r = 0.47) in hypertensives only. We presume that tubular injury at an early stage of renal damage in patients with essential hypertension could be a part of metabolic syndrome X...
  20. ncbi request reprint The influence of ozonated autohemotherapy on oxidative stress in hemodialyzed patients with atherosclerotic ischemia of lower limbs
    L Tylicki
    Department of Nephrology, Transplantology and Internal Medicine Medical University of Gdansk, Gdansk, Poland
    Int J Artif Organs 26:297-303. 2003
    ..It seems likely that the antioxidant defense system, part of which is glutathione, neutralizes oxidative properties of ozone in this concentration and protects against oxidative cell damage...
  21. ncbi request reprint Tubular injury: the first symptom of hypertensive kidney involvement?
    Leszek Tylicki
    Department of Nephrology, Medical University, Gdansk, Poland
    Med Sci Monit 9:CR135-41. 2003
    ..We attempted to determine whether tubular injury precedes glomerular involvement, and to evaluate the role of vascular damage and metabolic disturbances in this process...
  22. ncbi request reprint Effect of pentoxifylline on proteinuria, markers of tubular injury and oxidative stress in non-diabetic patients with chronic kidney disease - placebo controlled, randomized, cross-over study
    Marcin Renke
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Acta Biochim Pol 57:119-23. 2010
    ..Pentoxifylline (PTE) is a non-specific phosphodiesterase inhibitor with anti-inflammatory properties. It has been reported to have promising effects in CKD treatment...
  23. ncbi request reprint [Cyclophosphamide pulse therapy in patients with primary glomerulonephritis]
    B Rutkowski
    Klinika Chorób Nerek AM, 80 211 Gdansk, ul Debinki 7
    Przegl Lek 57:624-7. 2000
    ..Before cyclophosphamide pulse therapy all patients were pretreated with steroids, 3 pulses of 1.0 g Methylprednisolone and then oral prednisone in the dose 20 mg/m2 body surface...
  24. ncbi request reprint Low-dose dual blockade of the renin-angiotensin system improves tubular status in non-diabetic proteinuric patients
    Marcin Renke
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Scand J Urol Nephrol 39:511-7. 2005
    ..This therapeutic strategy is not used for proteinuric patients who are not able to receive high doses of angiotensin-converting enzyme inhibitor or angiotensin II receptor antagonists...
  25. doi request reprint The effect of N-acetylcysteine on proteinuria and markers of tubular injury in non-diabetic patients with chronic kidney disease. A placebo-controlled, randomized, open, cross-over study
    Marcin Renke
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Kidney Blood Press Res 31:404-10. 2008
    ..There is still no optimal therapy which can stop the progression of chronic kidney disease. Antioxidants such as N-acetylcysteine (NAC) have been reported as a promising strategy in this field...
  26. ncbi request reprint Low-dose angiotensin II receptor antagonists and angiotensin II-converting enzyme inhibitors alone or in combination for treatment of primary glomerulonephritis
    Marcin Renke
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Scand J Urol Nephrol 38:427-33. 2004
    ..Clinical data comparing the renal effects of ACEIs and ARBs, either singly or in combination, are scarce and usually concern the use of standard or high doses...
  27. ncbi request reprint [Pentoxifylline old drug or new hope for nephrology?]
    Marcin Renke
    Katedra i Klinika Nefrologii Transplantologii i Chorób Wewnetrznych Akademia Medyczna, Gdansk
    Przegl Lek 65:358-61. 2008
    ..This may occur due to inhibition of proinflammatory cytokine production. Probably in the next few years we will get answer to the question of PTF role in nephrology...
  28. ncbi request reprint [Clinical state of a patient with nephrotic proteinuria successfully treated with combined therapy with angiotensin II receptor antagonists and angiotensin II converting enzyme inhibitors and pentoxifylline]
    Marcin Renke
    Katedra i Klinika Nefrologii, Transplantologii i Chorób Wewnetrznych AM, Gdansk 80 211, ul Debinki 7
    Przegl Lek 65:312-4. 2008
    ..8 g, serum creatinine was 1.4 mg/dl and potassium 5.4 mmol/l. Next PTF 800 mg/day was added and DPE fell to 0.55 g after 2 months' therapy. Similar DPE was after 6 months (0.53 g) since we started with combination of IKA, ARA and PTF...
  29. ncbi request reprint Ozonated autohemotherapy in patients on maintenance hemodialysis: influence on lipid profile and endothelium
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Artif Organs 28:234-7. 2004
    ..It may stimulate beneficial changes in serum lipid profile manifesting as a decrease in the total- and LDL-cholesterol levels...
  30. ncbi request reprint Low-dose dual blockade of the renin-angiotensin system in patients with primary glomerulonephritis
    Przemyslaw Rutkowski
    Department of Nephrology, Transplantology, and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    Am J Kidney Dis 43:260-8. 2004
    ..We compared the concomitant use of benazepril, 5 mg, and losartan, 25 mg, and monotherapy with these agents in doses 2-fold greater...
  31. ncbi request reprint Fistula function and dialysis adequacy during ozonotherapy in chronically hemodialyzed patients
    Leszek Tylicki
    Department of Nephrology, Medical University of Gdansk, Gdansk, Poland
    Artif Organs 28:513-7. 2004
    ..The improvement of fistula function, expressed as a decrease in recirculation, is not significant, although seen in the majority of patients...
  32. ncbi request reprint Antioxidants: a possible role in kidney protection
    Leszek Tylicki
    Department of Nephrology, Transplantology and Internal Medicine, Medical University, Gdansk, Poland
    Kidney Blood Press Res 26:303-14. 2003
    ..Prospective, controlled clinical trials on safety and effectiveness of different therapeutic antioxidant strategies are indispensable...
  33. ncbi request reprint Treatment of hypertension in renal transplant recipients
    Leszek Tylicki
    Department of Internal Medicine, Nephrology and Transplantology, Medical University of Gdansk, Gdansk, Poland
    Curr Opin Urol 13:91-8. 2003
    ..Hypertension is very common in renal transplant recipients and is a significant risk factor for mortality from cardiovascular diseases and for development of graft dysfunction...
  34. ncbi request reprint Multifactorial determination of hypertensive nephroangiosclerosis
    Leszek Tylicki
    Department of Internal Medicine, Nephrology and Transplantology, Medical University, Gdansk, Poland
    Kidney Blood Press Res 25:341-53. 2002
    ..Determination of all risk factors may identify patients at high risk of renal failure and help tailor an appropriate management. In the present paper, the knowledge available on this clinically important objective is discussed...
  35. doi request reprint Spironolactone attenuates oxidative stress in patients with chronic kidney disease
    Marcin Renke
    Hypertension 52:e132-3; author reply e134. 2008
  36. doi request reprint Effects of N-acetylcysteine on angiotensin-converting enzyme plasma activity in patients with chronic kidney diseases
    Leszek Tylicki
    Blood Purif 26:354. 2008
  37. ncbi request reprint Ozonetherapy in a dialyzed patient with calcific uremic arteriolopathy
    Bogdan Biedunkiewicz
    Kidney Int 64:367-8. 2003
  38. ncbi request reprint [Hypertensive nephropathy: pathogenesis, diagnosis and treatment]
    Leszek Tylicki
    Klinika Nefrologii, Transplantologii i Chorób Wewnetrznych Akademii Medycznej w Gdańsku
    Pol Merkur Lekarski 14:168-73. 2003
    ..Pathogenesis, epidemiology, and clinical management of hypertensive nephropathy are currently discussed in this brief review...
  39. ncbi request reprint [Pathogenetic and epidemiological aspects of hypertensive nephropathy]
    Bolesław Rutkowski
    Kliniki Nefrologii, Transplantologii i Chorób Wewnetrznych AM w Gdańsku
    Pol Arch Med Wewn 110:1167-71. 2003
  40. ncbi request reprint Tubulointerstitial injury: early or late event in the pathogenesis of hypertensive nephropathy?
    Leszek Tylicki
    Kidney Int 65:1971-2; author reply 1972. 2004
  41. ncbi request reprint Metabolic disturbances as strong determinator of kidney injury in essential hypertension
    Leszek Tylicki
    J Hypertens 23:1433-4. 2005