Research Topics
| Marianna SzczypkaSummaryCountry: Poland Publications
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Publications
Modulation of Th1/Th2 cytokine production by selective and nonselective phosphodiesterase inhibitors administered to miceMarianna Szczypka
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Norwida 31, PL 50 375 Wrocław, Poland
Pharmacol Rep 64:179-84. 2012..These results indicate that nonstimulated lymphocytes Th1 and Th2 exhibited a slight sensitivity to aminophylline and sildenafil. The drugs under investigation were ineffective inhibitors of Th1/Th2 cytokine production...
The effects of selective and nonselective phosphodiesterase inhibitors on phagocytic cells in miceMarianna Szczypka
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
Immunopharmacol Immunotoxicol 32:507-13. 2010..A single administration of the drugs did not change the oxidative burst activity. PDE inhibitors administered five times temporarily enhanced the percentage of cells producing reactive oxidants...
Modulating effects of nonselective and selective phosphodiesterase inhibitors on lymphocyte subsets and humoral immune response in miceMarianna Szczypka
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Norwida 31, PL 50 375 Wrocław, Poland
Pharmacol Rep 62:1148-58. 2010..No effect or slight influence of the drugs on anti-SRBC hemagglutinins was observed, but the number of plaque-forming splenocytes was increased. The drugs under investigation did not show a significant immunosuppressive effect...
Modulation of cellular immune response by orbifloxacin in noninfected and E. coli-infected miceMarianna Szczypka
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Agricultural University, Wrocław, Poland
Immunopharmacol Immunotoxicol 27:461-72. 2005..Orbifloxacin exerted a modulating effect on the subsets of lymphocytes in thymus, spleen, and mesenteric lymph node cells in noninfected and E. coli-infected mice...
Modulatory effects of chitosan adipate on the T and B lymphocyte subsets in miceBozena Obminska-Mrukowicz
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Agricultural University, Norwida 31, 50 375 Wroc aw, Poland
J Vet Sci 7:157-60. 2006..Overall, chitosan adipate induces the maturation and differentiation of thymocytes, and regulates the number of B splenic cells and lymph node T cells irrespective of the number of doses...
Influences of DTC and zinc supplementation on the cellular response restoration in restrained miceBozena Obminska-Mrukowicz
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Agricultural University, Norwida 31, 50 375 Wroclaw, Poland
J Vet Sci 6:25-32. 2005..The obtained results show that DTC administration can be supplemented with zinc in order to restore the immune system impaired by stress...
The effects of bestatin on humoral response to sheep erythrocytes in non-treated and cyclophosphamide-immunocompromised miceMagdalena Lis
Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
Immunopharmacol Immunotoxicol 35:133-8. 2013....
