D Soszynski

Summary

Country: Poland

Publications

  1. ncbi request reprint Endotoxin tolerance does not alter open field-induced fever in rats
    D Soszynski
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    Physiol Behav 63:689-92. 1998
  2. ncbi request reprint [The pathogenesis and the adaptive value of fever]
    Dariusz Soszynski
    Katedra i Zakład Fizjologii Akademii Medycznej im Ludwika Rydygiera w Bydgoszczy
    Postepy Hig Med Dosw 57:531-54. 2003
  3. ncbi request reprint Inhibition of nitric oxide synthase delays the development of tolerance to LPS in rats
    Dariusz Soszynski
    Department of Physiology, The Ludwik Rydygier Medical University, 24 Karlowicza Street, Bydgoszcz PL 85 092, Poland
    Physiol Behav 76:159-69. 2002
  4. ncbi request reprint Blockade of nitric oxide formation enhances thermal and behavioral responses in rats during turpentine abscess
    D Soszynski
    Department of Physiology, Ludwik Rydygier Medical University, Bydgoszcz, Poland
    Neuroimmunomodulation 8:188-96. 2000
  5. ncbi request reprint The inhibition of nitric oxide synthase suppresses LPS- and psychological-stress-induced fever in rats
    D Soszynski
    Department of Physiology, The Ludwik Rydygier Medical University, 24 Karlowicza Str, PL-85-092 Bydgoszcz, Poland. dareks!aci.amb.bydgoszcz.pl
    Physiol Behav 72:65-72. 2001
  6. ncbi request reprint Hemorrhage suppresses fever, interleukin-6, and tumor necrosis factor-alpha responses to lipopolysaccharide in rats
    D Soszynski
    Lovelace Respiratory Research Institute, Albuquerque, N Mex, USA
    Neuroimmunomodulation 3:239-46. 1996
  7. ncbi request reprint IL-6 and IL-1 beta in fever. Studies using cytokine-deficient (knockout) mice
    W Kozak
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Ann N Y Acad Sci 856:33-47. 1998
  8. ncbi request reprint Beta-adrenergic receptor subtype effects on stress fever and thermoregulation
    K P Mayfield
    Lovelace Respiratory Research Institute, Albuquerque, NM 87185, USA
    Neuroimmunomodulation 6:305-17. 1999
  9. ncbi request reprint Role of fever in disease
    M J Kluger
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Ann N Y Acad Sci 856:224-33. 1998
  10. ncbi request reprint Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms
    M L Sopori
    Division of Pathophysiology, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Psychoneuroendocrinology 23:189-204. 1998

Detail Information

Publications11

  1. ncbi request reprint Endotoxin tolerance does not alter open field-induced fever in rats
    D Soszynski
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    Physiol Behav 63:689-92. 1998
    ..To test this hypothesis, we compared open field-induced fevers in rats made endotoxin tolerant to those rats not endotoxin tolerant. We found that endotoxin tolerance had no effect on open field fevers...
  2. ncbi request reprint [The pathogenesis and the adaptive value of fever]
    Dariusz Soszynski
    Katedra i Zakład Fizjologii Akademii Medycznej im Ludwika Rydygiera w Bydgoszczy
    Postepy Hig Med Dosw 57:531-54. 2003
    ..Based on the data reviewed in this article, it can be concluded that fever has evolved as a host defense mechanism which was preserved within the animal kingdom through hundreds of millions of years of evolution...
  3. ncbi request reprint Inhibition of nitric oxide synthase delays the development of tolerance to LPS in rats
    Dariusz Soszynski
    Department of Physiology, The Ludwik Rydygier Medical University, 24 Karlowicza Street, Bydgoszcz PL 85 092, Poland
    Physiol Behav 76:159-69. 2002
    ..Third injection of LPS did not elevate nitrite level in plasma. Taken together, presented data provide clear evidence that NO formation is involved in mechanisms responsible for development of early-stage tolerance to endotoxin...
  4. ncbi request reprint Blockade of nitric oxide formation enhances thermal and behavioral responses in rats during turpentine abscess
    D Soszynski
    Department of Physiology, Ludwik Rydygier Medical University, Bydgoszcz, Poland
    Neuroimmunomodulation 8:188-96. 2000
    ..e. anorexia, cachexia) in response to localized tissue inflammation caused by injection of turpentine in freely moving biotelemetered rats...
  5. ncbi request reprint The inhibition of nitric oxide synthase suppresses LPS- and psychological-stress-induced fever in rats
    D Soszynski
    Department of Physiology, The Ludwik Rydygier Medical University, 24 Karlowicza Str, PL-85-092 Bydgoszcz, Poland. dareks!aci.amb.bydgoszcz.pl
    Physiol Behav 72:65-72. 2001
    ..L-NAME significantly suppressed the stress fever without any effect on changes in motor activity. Presented data provide clear evidence that NO formation is involved in LPS- and psychological-stress-induced fevers in rats...
  6. ncbi request reprint Hemorrhage suppresses fever, interleukin-6, and tumor necrosis factor-alpha responses to lipopolysaccharide in rats
    D Soszynski
    Lovelace Respiratory Research Institute, Albuquerque, N Mex, USA
    Neuroimmunomodulation 3:239-46. 1996
    ..Hemorrhage-induced high level of corticosterone might contribute to the attenuation of fever, perhaps via the suppression of pyrogenic cytokines...
  7. ncbi request reprint IL-6 and IL-1 beta in fever. Studies using cytokine-deficient (knockout) mice
    W Kozak
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Ann N Y Acad Sci 856:33-47. 1998
    ..Our data demonstrate that in the mouse, IL-1 beta and IL-6 are critical for the induction of fever during local inflammation, whereas in systemic inflammation they appear only to contribute to fever...
  8. ncbi request reprint Beta-adrenergic receptor subtype effects on stress fever and thermoregulation
    K P Mayfield
    Lovelace Respiratory Research Institute, Albuquerque, NM 87185, USA
    Neuroimmunomodulation 6:305-17. 1999
    ..We hypothesize that the blockade of stress-induced fever by beta-blockers may be due to the sedative actions of these drugs...
  9. ncbi request reprint Role of fever in disease
    M J Kluger
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Ann N Y Acad Sci 856:224-33. 1998
    ..In short, we speculate that patients who would not have survived severe sepsis in the past are now being kept alive and that the occasionally high fevers seen in these patients may be maladaptive...
  10. ncbi request reprint Effect of nicotine on the immune system: possible regulation of immune responses by central and peripheral mechanisms
    M L Sopori
    Division of Pathophysiology, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Psychoneuroendocrinology 23:189-204. 1998
    ..These results support the hypothesis that NT alters immune responses by directly interacting with T cells, as well as indirectly through brain-immune interactions...
  11. ncbi request reprint Molecular mechanism of emotional fever--the role of nitric oxide
    D Soszynski
    Department of Neuroimmunology, The Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland
    J Physiol Pharmacol 57:51-9. 2006
    ....