Research Topics
| D RachonSummaryCountry: Poland Publications
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Publications
In vitro effects of benzophenone-2 and octyl-methoxycinnamate on the production of interferon-gamma and interleukin-10 by murine splenocytesDominik Rachon
Department of Immunology, Medical University of Gdansk, Poland
Immunopharmacol Immunotoxicol 28:501-10. 2006..These effects were comparable to those of E2. Our results clearly show that UV-screens at high doses also may possess immunomodulatory effects some of which resemble those of E2...- Effects of dietary equol on body weight gain, intra-abdominal fat accumulation, plasma lipids, and glucose tolerance in ovariectomized Sprague-Dawley ratsDominik Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Gottingen, Germany
Menopause 14:925-32. 2007.... - Effects of intranasal 17beta-estradiol administration on serum bioactive interleukin-6 and C-reactive protein levels in healthy postmenopausal womenDominik Rachon
Department of Immunology, Medical University of Gdansk, Gdansk, Poland
Menopause 13:840-5. 2006..The aim of our study was to investigate the effects of intranasal 17beta-estradiol (E2) on serum CRP and its most potent stimulant, interleukin-6 in healthy postmenopausal women... - In vitro effects of genistein and resveratrol on the production of interferon-gamma (IFNgamma) and interleukin-10 (IL-10) by stimulated murine splenocytesD Rachon
Department of Immunology, Medical University of Gdansk, ul Debinki 1, 80 210 Gdansk, Poland
Phytomedicine 13:419-24. 2006..From our in vitro experiments we conclude that genistein and resveratrol, similarly to E2, by decreasing the IFNgamma/IL10 ratio may shift the Th1/Th2 balance towards the Th2 response... - Effects of dietary equol on the pituitary of the ovariectomized ratsD Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Robert Koch Strasse 40, Gottingen, Germany
Horm Metab Res 39:256-61. 2007..In conclusion, high dose dietary equol administration to ovx rats exerts estrogenic like effects on the lactotropes and anti-estrogenic on the gonadotropes... - [Role of tumor necrosis factor (TNF) and interleukin-6 (IL-6) in the pathogenesis of late complications of menopause. Effects of hormone replacement therapy on TNF and IL-6 expression]Dominik Rachon
Zakład Immunologii, AM w Gdańsku
Pol Merkur Lekarski 18:724-7. 2005..Therefore, the mechanisms underlying the protective effects of HRT can also be attributed to its immunomodulating properties which seem to restore cytokine homeostasis in postmenopausal women... - Prevalence and risk factors of anabolic-androgenic steroids (AAS) abuse among adolescents and young adults in PolandDominik Rachon
Department of Immunology, Medical University of Gdansk, Poland
Soz Praventivmed 51:392-8. 2006..To estimate the prevalence of anabolic-androgenic steroids (AAS) abuse among adolescent and young adults in Poland... - Effects of dietary equol administration on the mammary gland in ovariectomized Sprague-Dawley ratsDominik Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Gottingen, Germany
Menopause 15:340-5. 2008..To evaluate the effects of dietary equol, a metabolite of soy-derived daidzein or formononetin present in red clover, on the mammary gland of ovariectomized Sprague-Dawley rats... - Dietary quercetin does not affect pituitary lutenizing hormone (LH) expression and has no uterotropic effects in ovariectomized Sprague-Dawley ratsDominik Rachon
Department of Immunology, Medical University of Gdansk, ul Debinki 1, 80 210 Gdansk, Poland
Food Chem Toxicol 46:513-8. 2008..The aim of this study was to investigate the potency of LH suppression and the uterotrophic effects of quercetin, a flavonoid widely present in our diet which in vitro has been shown to posses estrogenic properties... - Effects of dietary equol administration on ovariectomy induced bone loss in Sprague-Dawley ratsDominik Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
Maturitas 58:308-15. 2007..Oestrogen deficiency leads to a considerable bone loss, thus, osteopenia and osteoporosis are serious complications after menopause... - Dietary daidzein and puerarin do not affect pituitary LH expression but exert uterotropic effects in ovariectomized ratsDominik Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
Maturitas 57:161-70. 2007.... - Uterotropic effects of dietary equol administration in ovariectomized Sprague-Dawley ratsD Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Gottingen, Germany
Climacteric 10:416-26. 2007..The aim of the present study was to evaluate the uterotropic effects of the administration of dietary equol, a metabolite of soy-derived daidzein or formononetin present in red clover, in an ovariectomized rat model of menopause... - Serum interleukin-6 levels and bone mineral density at the femoral neck in post-menopausal women with Type 1 diabetesD Rachon
Department of Immunology, Medical University of Gdansk, Gdansk, Poland
Diabet Med 20:475-80. 2003..Enhanced interleukin-6 (IL-6) production among Type 1 diabetic patients could be involved in the pathogenesis of diabetic bone loss since it is a potent bone resorbing cytokine... - Recombinant human erythropoietin stimulates production of interleukin 2 by whole blood cell cultures of hemodialysis patientsE Bryl
Department of Immunology, Medical University of Gdansk, Poland
Artif Organs 23:809-16. 1999..Our studies show that the therapy with rhEPO affects IL-2 secretion... - High levels of circulating interleukin-10 in diabetic nephropathy patientsJolanta Mysliwska
Department of Immunology, Medical University of Gdansk, ul Debinki 1, 80 210 Gdansk, Poland
Eur Cytokine Netw 16:117-22. 2005..Since IL-10 has met the criteria for an anti-inflammatory and an immunosuppressive cytokine, its activity may be important for clinical outcome of DN... 
Effects of black cohosh extract on body weight gain, intra-abdominal fat accumulation, plasma lipids and glucose tolerance in ovariectomized Sprague-Dawley ratsDominik Rachon
Department of Clinical and Experimental Endocrinology, University of Gottingen, Gottingen, Germany
Maturitas 60:209-15. 2008..Recent data from randomized controlled studies have shown that CR consumption alleviates "hot flushes" and due to the lack of uterotropic effects can be a safe alternative to estrogen replacement therapy...- Natural killer activity and thyroid hormone levels in young and elderly personsZ Kmiec
Department of Histology, 3rd Department of Internal Medicine, Medical University of Gdansk, Poland
Gerontology 47:282-8. 2001..The purpose of the study is to compare NK cytotoxic activity and serum concentrations of TSH and thyroid hormones in healthy old and young people, and to assess in vitro the effects of triiodothyronine (T(3)) on NK activity... - The second to fourth digit ratio in elite and non-elite female athletesLeszek Pokrywka
Department of Histology, Medical University of Gdansk, Gdansk, Poland
Am J Hum Biol 17:796-800. 2005..05). Therefore, we can speculate that low 2D:4D ratio may be a positive correlate of sports potential in females... 
No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patientsLeszek Tylicki
Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, ul Debinki 7, 80 211 Gdansk, Poland
Mediators Inflamm 13:377-80. 2004..Ozone as a strong oxidant may induce an inflammatory response...- Inflammatory response of coronary artery disease postmenopausal women is associated with the IVS1-397T > C estrogen receptor alpha polymorphismJolanta Mysliwska
Department of Immunology, Medical University of Gdansk, ul Debinki 1, 80 210 Gdansk, Poland
Clin Immunol 130:355-64. 2009.... - Effects of oestrogen deprivation on interleukin-6 production by peripheral blood mononuclear cells of postmenopausal womenD Rachon
Department of Histology and Immunology of the Medical University of Gdańsk, 80 210 Gdansk, ul Debinki 1, Poland
J Endocrinol 172:387-95. 2002.... - Natural killer cell activity unaffected by ozonated autohemotherapy in patients with end-stage renal disease on maintenance renal replacement therapyB Biedunkiewicz
Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Poland
Int J Artif Organs 27:766-71. 2004..98 +/- 6.67), and after nine sessions of O3-AHT (18.26 +/- 8.82). In conclusion, our findings showed that O3-AHT in a dose of 50 mg/mL does not have any significant influence on natural killer cell function in hemodialyzed patients... - Ovarian function and obesity--interrelationship, impact on women's reproductive lifespan and treatment optionsDominik Rachon
Department of Clinical Nutrition, Medical University of Gdansk, Gdansk, Poland
Mol Cell Endocrinol 316:172-9. 2010..This review focuses on the interrelationship between the ovarian function and obesity as well as its treatment strategies...