J K Rybakowski

Summary

Affiliation: Poznan University of Medical Sciences
Country: Poland

Publications

  1. ncbi Prophylactic lithium response and polymorphism of the brain-derived neurotrophic factor gene
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacopsychiatry 38:166-70. 2005
  2. ncbi [Bipolarity among unipolar affective disorder patients--uniDEP-BI national multi-site study]
    Andrzej Kiejna
    Katedra i Klinika Psychiatrii AM we Wrocłławiu
    Psychiatr Pol 39:951-62. 2005
  3. ncbi Association of tumor necrosis factor -308G/A promoter polymorphism with schizophrenia and bipolar affective disorder in a Polish population
    Piotr M Czerski
    Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 57:88-94. 2008
  4. pmc Matrix Metalloproteinase-9 (MMP9)-A Mediating Enzyme in Cardiovascular Disease, Cancer, and Neuropsychiatric Disorders
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Cardiovasc Psychiatry Neurol 2009:904836. 2009
  5. pmc Screening for the markers of kidney damage in men and women on long-term lithium treatment
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Med Sci Monit 18:CR656-60. 2012
  6. doi Single ketamine infusion in bipolar depression resistant to antidepressants: are neurotrophins involved?
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Hum Psychopharmacol 28:87-90. 2013
  7. ncbi Increased serum matrix metalloproteinase-9 (MMP-9) levels in young patients during bipolar depression
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    J Affect Disord 146:286-9. 2013
  8. doi TEMPS-A and long-term lithium response: positive correlation with hyperthymic temperament
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    J Affect Disord 145:187-9. 2013
  9. doi Treatment of depression in first episode of schizophrenia: results from EUFEST
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Eur Neuropsychopharmacol 22:875-82. 2012
  10. doi Use of the Hypomania Checklist-32 and the Mood Disorder Questionnaire for detecting bipolarity in 1051 patients with major depressive disorder
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572, Poznan, Poland
    Eur Psychiatry 27:577-81. 2012

Detail Information

Publications76

  1. ncbi Prophylactic lithium response and polymorphism of the brain-derived neurotrophic factor gene
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacopsychiatry 38:166-70. 2005
    ..The aim of this study was to find a possible association between lithium prophylactic effect in bipolar patients and two polymorphisms of BDNF gene...
  2. ncbi [Bipolarity among unipolar affective disorder patients--uniDEP-BI national multi-site study]
    Andrzej Kiejna
    Katedra i Klinika Psychiatrii AM we Wrocłławiu
    Psychiatr Pol 39:951-62. 2005
    ..The main objective of the study was to evaluate the occurrence of bipolarity among outpatients with a recurrent major depressive disorder...
  3. ncbi Association of tumor necrosis factor -308G/A promoter polymorphism with schizophrenia and bipolar affective disorder in a Polish population
    Piotr M Czerski
    Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 57:88-94. 2008
    ..Only 3 such studies were performed in BPAD. The aim of our study was to perform a case-control association analysis of the TNF -308G/A polymorphism in a Polish sample of patients with SCH, BPAD and healthy controls...
  4. pmc Matrix Metalloproteinase-9 (MMP9)-A Mediating Enzyme in Cardiovascular Disease, Cancer, and Neuropsychiatric Disorders
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Cardiovasc Psychiatry Neurol 2009:904836. 2009
    ....
  5. pmc Screening for the markers of kidney damage in men and women on long-term lithium treatment
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Med Sci Monit 18:CR656-60. 2012
    ..Therefore, the aim of the study was to assess kidney function in a group of long-term lithium-treated patients...
  6. doi Single ketamine infusion in bipolar depression resistant to antidepressants: are neurotrophins involved?
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Hum Psychopharmacol 28:87-90. 2013
    ....
  7. ncbi Increased serum matrix metalloproteinase-9 (MMP-9) levels in young patients during bipolar depression
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    J Affect Disord 146:286-9. 2013
    ..In this first study of serum MMP-9 in psychiatric illness, we estimated it in patients with bipolar mood disorder both during depression or mania as well as during immediate remission after these episodes...
  8. doi TEMPS-A and long-term lithium response: positive correlation with hyperthymic temperament
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    J Affect Disord 145:187-9. 2013
    ..Such a possibility occurred with an advent of temperament scale for bipolar disorder and of an ability to quantitatively assess lithium prophylactic response...
  9. doi Treatment of depression in first episode of schizophrenia: results from EUFEST
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Eur Neuropsychopharmacol 22:875-82. 2012
    ..In summary, the results of EUFEST did not demonstrate a differential effect of the antipsychotics studied on depressive symptomatology in patients with first episode schizophrenia...
  10. doi Use of the Hypomania Checklist-32 and the Mood Disorder Questionnaire for detecting bipolarity in 1051 patients with major depressive disorder
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572, Poznan, Poland
    Eur Psychiatry 27:577-81. 2012
    ..To use the hypomania checklist (HCL-32) and the mood disorder questionnaire (MDQ), for detecting bipolarity in depressed patients...
  11. doi Clinical and pathogenic aspects of candidate genes for lithium prophylactic efficacy
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    J Psychopharmacol 26:368-73. 2012
    ..Possible aspects of these genes with regard to the mechanism of lithium activity and pathogenesis of bipolar mood disorder are discussed...
  12. doi Excellent lithium responders have normal cognitive functions and plasma BDNF levels
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Int J Neuropsychopharmacol 13:617-22. 2010
    ..ELRs may constitute a specific subgroup of bipolar patients in which long-term lithium administration can produce complete normality...
  13. ncbi Long-term pharmacological treatment of bipolar disorders
    Janusz Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Neuro Endocrinol Lett 28:71-93. 2007
    ..Some issues connected with polypharmacy targeting optimal maintenance results are discussed. In addition, the long-term management and the role of antidepressants in treatment of non-bipolar I illness is also briefly described...
  14. doi Painting "mania"
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    J Affect Disord 128:319-20. 2011
    ..The painting was done in 2001 following the acute manic episode in the course of bipolar mood disorder in the artist...
  15. ncbi Impairment of endothelial function in unipolar and bipolar depression
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Biol Psychiatry 60:889-91. 2006
    ..We therefore tested this hypothesis in patients with depression in the course of mood disorders and assessed the effect of antidepressant treatment...
  16. ncbi Performance on the Wisconsin Card Sorting Test in schizophrenia and genes of dopaminergic inactivation (COMT, DAT, NET)
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Psychiatry Res 143:13-9. 2006
    ..A limitation to the interpretation of results could be small number of patients studied as well as variable psychopathological state and medication during cognitive testing...
  17. ncbi Prefrontal cognition in schizophrenia and bipolar illness in relation to Val66Met polymorphism of the brain-derived neurotrophic factor gene
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Psychiatry Clin Neurosci 60:70-6. 2006
    ..An association of this polymorphism with performance on the N-back test in schizophrenia and not in bipolar illness may suggest that in schizophrenia, the BDNF system may be connected with early phases of information processing...
  18. ncbi Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Am J Med Genet B Neuropsychiatr Genet 144:820-3. 2007
    ..The results obtained may show a significant epistatic interaction between 5-HTTLPR and BDNF polymorphism, and response to lithium prophylaxis...
  19. doi Functional polymorphism of the matrix metalloproteinase-9 (MMP-9) gene in schizophrenia
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Schizophr Res 109:90-3. 2009
    ..The results may provide the first evidence for involvement of the MMP-9 gene in the pathogenesis of schizophrenia and could also contribute to explaining a genetic connection between schizophrenia and some somatic illnesses...
  20. doi Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacopsychiatry 42:20-2. 2009
    ..The aim of the present study was to investigate a possible association of this polymorphism with the quality of the prophylactic lithium response in bipolar patients...
  21. doi BDNF gene: functional Val66Met polymorphism in mood disorders and schizophrenia
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Science, Szpitalna 27 33, 60 572 Poznan, Poland
    Pharmacogenomics 9:1589-93. 2008
    ..It has been demonstrated that the functional Val66Met polymorphism of the gene can be associated with a number of clinical and pharmacological phenomena in these illnesses...
  22. ncbi Matrix metalloproteinase-9 gene and bipolar mood disorder
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572, Poznan, Poland
    Neuromolecular Med 11:128-32. 2009
    ....
  23. doi Polish version of the Hypomania Checklist (HCL-32) scale: the results in treatment-resistant depression
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, Poznan, Poland
    Eur Arch Psychiatry Clin Neurosci 260:139-44. 2010
    ..9 vs. 30.0%, respectively, P < 0.001). Therefore, using Polish version of HCL-32 we have confirmed the association between bipolarity and worse response to antidepressant drugs in patients with mood disorders...
  24. doi Response to prophylactic lithium in bipolar disorder may be associated with a preservation of executive cognitive functions
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Eur Neuropsychopharmacol 19:791-5. 2009
    ..Therefore, the favorable effect of lithium prophylaxis may be associated with a preservation of executive cognitive functions and the offspring of bipolar patients shows an impairment of such functions...
  25. ncbi Long-term administration of the low-dose risperidone in schizotaxia subjects
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Hum Psychopharmacol 22:407-12. 2007
    ..Discontinuation of treatment after 3-4 years did not cause deterioration of functioning...
  26. ncbi Polymorphisms of the Fyn kinase gene and a performance on the Wisconsin Card Sorting Test in schizophrenia
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Psychiatr Genet 17:201-4. 2007
    ....
  27. doi Lithium in neuropsychiatry: a 2010 update
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poland
    World J Biol Psychiatry 12:340-8. 2011
    ..CONCLUSIONS. Although not promoted by pharmaceutical companies, lithium remains a highly important drug in neuropsychiatry...
  28. doi Functional polymorphism of matrix metalloproteinase-9 (MMP-9) gene and response to lithium prophylaxis in bipolar patients
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poland
    Hum Psychopharmacol 26:168-71. 2011
    ..Therefore, we investigated a possible association between functional polymorphisms of the MMP-9 gene and the response to lithium, the main mood-stabilizing drug in bipolar illness...
  29. doi Bipolarity and inadequate response to antidepressant drugs: clinical and psychopharmacological perspective
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    J Affect Disord 136:e13-9. 2012
    ..Additional evidence for such a connection may be the efficacy of mood-stabilizing drugs in the augmentation of antidepressants in treatment-resistant depression...
  30. ncbi One-year course of the first vs. multiple episodes of depression--Polish naturalistic study
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Eur Psychiatry 19:258-63. 2004
    ..The study was 1-year, prospective, naturalistic observation made by Polish psychiatrists...
  31. ncbi [Clinical picture and treatment of subsequent depressive episodes--results of Polish multicenter study]
    Janusz Rybakowski
    Kliniki Psychiatrii Doroslych AM w Poznaniu
    Psychiatr Pol 37:419-31. 2003
    ..A comparison of the clinical picture and treatment results of the first depressive episode with the second and the third and further depressive recurrence...
  32. ncbi Potentiation of antidepressants with lithium or carbamazepine in treatment-resistant depression
    J K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 40:134-9. 1999
    ..CBZ responders had lower baseline severity of depression than CBZ nonresponders and clinical improvement significantly correlated with increase in erythrocyte ATPase activity in the CBZ group...
  33. ncbi Bipolar mood disorders among Polish psychiatric outpatients treated for major depression
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    J Affect Disord 84:141-7. 2005
    ..The aim of the study was to assess the frequency of bipolar disorders among outpatients having at least one major depressive episode, treated by 96 psychiatrists, representing all regions of Poland...
  34. ncbi An association study of dopamine receptors polymorphisms and the Wisconsin Card Sorting Test in schizophrenia
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    J Neural Transm 112:1575-82. 2005
    ..The results may suggest an association between DRD1 gene polymorphism and performance on PFC test in schizophrenia. Also, the gender-dependent role of DRD2 in this process may be presumed...
  35. doi Bipolar mood disorder, creativity and schizotypy: an experimental study
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Psychopathology 44:296-302. 2011
    ....
  36. ncbi Eye movement disturbances in schizophrenia and a polymorphism of catechol-O-methyltransferase gene
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, ul Szpitalna 27 33, 60 572, Poznan, Poland
    Psychiatry Res 113:49-57. 2002
    ..They also point to possible gender differences as to the role of COMT in brain function in schizophrenia...
  37. ncbi Eye movement and neuropsychological studies in first-degree relatives of schizophrenic patients
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Schizophr Res 54:105-10. 2002
    ....
  38. ncbi The prophylactic effect of long-term lithium administration in bipolar patients entering treatment in the 1970s and 1980s
    J K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Bipolar Disord 3:63-7. 2001
    ....
  39. ncbi The dexamethasone/corticotropin-releasing hormone test in depression in bipolar and unipolar affective illness
    J K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Pozna, Poland
    J Psychiatr Res 33:363-70. 1999
    ..Within unipolar depression, this dysregulation may increase with the time course of the illness...
  40. ncbi Prophylactic effect of lithium in bipolar affective illness may be related to serotonin transporter genotype
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Szpitalna 27 33, 60 572 Poznan, Poland
    Pharmacol Rep 57:124-7. 2005
    ..A supposition is made that prophylactic management of bipolar illness can be optimized by defining 5-HTTLPR genotype...
  41. ncbi Polymorphism of the brain-derived neurotrophic factor gene and performance on a cognitive prefrontal test in bipolar patients
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Bipolar Disord 5:468-72. 2003
    ....
  42. doi Functional -1149 g/t polymorphism of the prolactin gene in schizophrenia
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 65:41-4. 2012
    ..Therefore, we investigated the functional polymorphism of the prolactin gene in schizophrenic patients compared with control subjects...
  43. ncbi Dopamine D3 receptor (DRD3) gene polymorphism is associated with the intensity of eye movement disturbances in schizophrenic patients and healthy subjects
    J K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Mol Psychiatry 6:718-24. 2001
    ..5 vs 43.8%, P < 0.01 and 8.3 vs 45.7, P < 0.005, respectively). We suggest that the DRD3 Ser9Gly polymorphism may be a contributing factor to the performance of eye movements used as a phenotypic marker of schizophrenia...
  44. doi The association study of three FYN polymorphisms with prophylactic lithium response in bipolar patients
    Aleksandra Szczepankiewicz
    Department of Pediatric Pulmonology, Allergy and Clinical Immunology, IIIrd Department of Pediatrics, Poznan University of Medical Sciences, Poznan, Poland
    Hum Psychopharmacol 24:287-91. 2009
    ..The results are discussed in light of our previous studies on FYN gene in bipolar illness and BDNF gene in lithium response...
  45. ncbi Association study of the glycogen synthase kinase-3beta gene polymorphism with prophylactic lithium response in bipolar patients
    Aleksandra Szczepankiewicz
    Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poland
    World J Biol Psychiatry 7:158-61. 2006
    ..The patients were delineated as excellent responders, partial responders and non-responders to lithium. The results obtained suggest that this polymorphism may not be related to the degree of prophylactic lithium response...
  46. ncbi Association analysis of the insertion/deletion polymorphism in serotonin transporter gene in patients with affective disorder
    Joanna Hauser
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Eur Psychiatry 18:129-32. 2003
    ..1% in bipolar, and 54.3 in unipolar vs 39.4% in controls). We suggest that the presence of allele s may increase the susceptibility to occurrence of affective disorder...
  47. ncbi Association studies of 5-HT2A and 5-HT2C serotonin receptor gene polymorphisms with prophylactic lithium response in bipolar patients
    Monika Dmitrzak-Weglarz
    Laboratory of Psychiatric Genetics at Department of Psychiatry, Poznan University of Medical Sciences, Szpitalna 27 33, PL 60 572 Poznan, Poland
    Pharmacol Rep 57:761-5. 2005
    ..The patients were classified as excellent responders, partial responders and non-responders to lithium. The obtained results suggest that these polymorphisms may not be related to the degree of prophylactic lithium response...
  48. ncbi Dopamine receptor D1 gene -48A/G polymorphism is associated with bipolar illness but not with schizophrenia in a Polish population
    Monika Dmitrzak-Weglarz
    Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 53:46-50. 2006
    ..022). These data suggest that the -48A/G polymorphism of the DRD1 gene may be involved in the etiology of bipolar disorder in a Polish population...
  49. ncbi The study of cytosolic phospholipase A2 gene polymorphism in schizophrenia using eye movement disturbances as an endophenotypic marker
    Janusz K Rybakowski
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 47:115-9. 2003
    ..Our results correspond to the other studies showing an association between the cPLA2 polymorphism and schizophrenia (predominance of the A2 allele in schizophrenic subjects)...
  50. ncbi Association analysis of brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism in schizophrenia and bipolar affective disorder
    Maria Skibinska
    Laboratory of Psychiatric Genetics, Department of Psychiatry, University of Medical Sciences, Poznan, Poland
    World J Biol Psychiatry 5:215-20. 2004
    ..328 for genotypes, p=0.253 for alleles in schizophrenia; p=0.032 for genotypes, p=0.858 for alleles in bipolar affective disorder)...
  51. ncbi Association analysis of the GSK-3beta T-50C gene polymorphism with schizophrenia and bipolar disorder
    Aleksandra Szczepankiewicz
    Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 53:51-6. 2006
    ..015 for genotypes and p=0.009 for alleles). In conclusion, this polymorphism may be associated with female gender in bipolar II disorder...
  52. doi Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients
    Monika Dmitrzak-Weglarz
    Laboratory of Psychiatric Genetics, Department of Psychiatry, University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Pharmacogenomics 9:1595-603. 2008
    ..No association with lithium response was revealed with the polymorphism of NTRK2 gene, neither with interaction of BDNF and NTRK2 genes...
  53. ncbi Quality of life, depressive symptoms and anxiety in hyperthyroid patients
    A Suwalska
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Rocz Akad Med Bialymst 50:61-3. 2005
    ..The aim of the study was to evaluate quality of life and to assess frequency and severity of depressive and anxiety symptoms in hyperthyroid patients...
  54. ncbi Effects of antidepressant mirtazapine on fibromyalgia symptoms
    W Samborski
    Department of Physiotherapy and Rheumatology, University of Medical Sciences, Poznan, Poland
    Rocz Akad Med Bialymst 49:265-9. 2004
    ..Pharmacological therapy with analgetic and nonsteroidal antiinflammatory drugs is not very effective. Positive effects were reported in some patients treated with antidepressant drugs, especially serotonergic agents...
  55. doi Serum brain-derived neurotrophic factor in euthymic bipolar patients on prophylactic lithium therapy
    A Suwalska
    Department of Adult Psychiatry, Rheumatology and Rehabilitation, Poznan University of Medical Sciences, ul Szpitalna 27 33, Poznan, Poland
    Neuropsychobiology 62:229-34. 2010
    ....
  56. doi FYN kinase gene: another glutamatergic gene associated with bipolar disorder?
    Aleksandra Szczepankiewicz
    Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Neuropsychobiology 59:178-83. 2009
    ..86, D' = 0.93 with 95% CI = 0.9-0.97). The results suggest that the glutamatergic FYN gene may be associated with bipolar disorder, particularly with type I illness and early age of onset...
  57. ncbi Open trial of mirtazapine in patients with fibromyalgia
    W Samborski
    Department of Rheumatology and Clinical Immunology, University of Medical Sciences, Poznan, Poland
    Pharmacopsychiatry 37:168-70. 2004
    ..Some positive therapeutic effects in fibromyalgia syndrome (FS) were reported with both tricyclic and new antidepressant drugs as well as serotonergic agents (5HT2 and 5HT3 receptor blockers)...
  58. ncbi Lack of association between polymorphisms of dopamine receptors, type D2, and bipolar affective illness in a Polish population
    Anna Leszczynska-Rodziewicz
    Department of Adult Psychiatry, University of Medical Sciences, Poznan, Poland
    Med Sci Monit 11:CR289-295. 2005
    ..Thus the genes of the dopaminergic system are good candidates for studies on bipolar disorder. In the present study, we investigated polymorphisms of dopamine receptors, type D2, including the dopamine receptors D2, D3 and D4...
  59. ncbi Screening of chromosomal region 21q22.3 for mutations in genes associated with neuronal Ca2+ signalling in bipolar affective disorder
    Andrzej Kostyrko
    Department of Biochemistry and Molecular Biology, University of Medical Sciences, Poznan, Poland
    Acta Biochim Pol 53:317-20. 2006
    ..However, this study does not exclude TRPM2 as a candidate gene since we have screened only about 30 per cent of the entire coding sequence of this large gene...
  60. ncbi L-thyroxine augmentation of serotonergic antidepressants in female patients with refractory depression
    Dorota Łojko
    Department of Adult Psychiatry, Poznan University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    J Affect Disord 103:253-6. 2007
    ..In this paper, the efficacy of addition of moderate dose of l-thyroxine (T4) to serotonergic antidepressants in refractory depression was evaluated...
  61. ncbi Types of depression more frequent in bipolar than in unipolar affective illness: results of the Polish DEP-BI study
    Janusz K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Psychopathology 40:153-8. 2007
    ..The study was performed in the framework of the DEP-BI project aimed at assessing the prevalence of bipolar disorders among depressive outpatients treated by psychiatrists in Poland...
  62. ncbi Depression in premenopausal women: gonadal hormones and serotonergic system assessed by D-fenfluramine challenge test
    Jolanta Rajewska
    Department of Adult Psychiatry, University of Medical Sciences, ul Szpitalna 27 33, 60 572, Poznan, Poland
    Prog Neuropsychopharmacol Biol Psychiatry 27:705-9. 2003
    ..The aim of the study was to compare the activity of gonadal hormones and serotonergic system in premenopausal women with or without depression in relation to clinical and hormonal indices of menopause...
  63. doi Vitamin B12 level may be related to the efficacy of single ketamine infusion in bipolar depression
    A Permoda-Osip
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacopsychiatry 46:227-8. 2013
    ..These preliminary data suggest that the vitamin B12 level may be connected with the efficacy of ketamine infusion in bipolar depression. ..
  64. doi Lithium Treatment of a Bipolar Patient with Wilson's Disease: A Case Report
    J K Rybakowski
    Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacopsychiatry 46:120-1. 2013
    ..Since then, the patient has been mostly in a euthymic mood with subclinical hypomanic periods. We suggest that lithium may be a viable option for treating bipolar illness in patients with Wilson's disease...
  65. ncbi Relationship between class I and II HLA antigens in schizophrenia and eye movement disturbances: a preliminary study
    Przemysław A Bogacki
    Department of Adult Psychiatry, University of Medical Sciences, ul Szpitalna 27 33, 60 572 Poznan, Poland
    Neuropsychobiology 51:204-10. 2005
    ..A limitation of this study is a small number of investigated patients with schizophrenia...
  66. ncbi Bipolar or unipolar? - the question for clinicians and researchers
    Andrzej Kiejna
    Department of Psychiatry, Wrocław Medical University, Wroclaw, Poland
    J Affect Disord 93:177-83. 2006
    ..Correct diagnosis and criteria of affective disorders is always a subject of interest to researchers and practitioners...
  67. ncbi [Lack of association between VNTR polymorphism of DAT gene and schizophrenia]
    Joanna Hauser
    Kliniki Psychiatrii Dorosłych AM w Poznaniu
    Psychiatr Pol 36:403-12. 2002
    ..In Caucasians the 40 base pair motif has 3 to 11 repeats, the most common (about 90%) are alleles containing 9 and 10 repeats. In the present study no association between the polymorphism studied and schizophrenia was found...
  68. ncbi Does risperidone act better in schizophrenic patients who have a family or obstetric history?
    Alina Borkowska
    Neuropsychology Unit, Department of Psychiatry, University School of Medicine, Ul Kurpinskiego 19, 85 096 Bydgoszcz, Poland
    Prog Neuropsychopharmacol Biol Psychiatry 26:1349-53. 2002
    ..The aim of the study was to assess the effect of treatment with risperidone on psychopathological symptoms and cognitive deficits in schizophrenic patients, in relation to family history, obstetric complications and duration of the illness...
  69. ncbi Low dose risperidone in the treatment of schizophrenia-like symptoms in high-risk subjects
    Janusz K Rybakowski
    J Clin Psychopharmacol 23:674-5. 2003
  70. ncbi The frontal lobe neuropsychological tests in patients with schizophrenia and/or obsessive-compulsive disorder
    Alina Borkowska
    Clinical Neurospsychological Unit, University School of Medicine, Bydgoszcz, Poland
    J Neuropsychiatry Clin Neurosci 15:359-62. 2003
    ..Schizophrenic patients without OC were the most impaired; and OCD patients were the least, while schizophrenic patients with OC scored between these two groups...
  71. ncbi Reboxetine, a new noradrenaline selective antidepressant, is at least as effective as fluoxetine in the treatment of depression
    Vittorino Andreoli
    Primario Servizi Psychiatri, Ospedale di Soave, Soave, Italy
    J Clin Psychopharmacol 22:393-9. 2002
    ..Reboxetine and fluoxetine are more effective than placebo in the treatment of major depression. Futhermore, both antidepressants are well tolerated but possess different adverse event profiles...
  72. ncbi Risperidone treatment of schizophrenia: improvement in psychopathology and neuropsychological tests
    Alina Borkowska
    Department of Psychiatry, University School of Medicine, Bydgoszcz, Poland
    Neuropsychobiology 46:85-9. 2002
    ..The results may suggest a common neurobiological substrate of negative and cognitive symptoms, reflected in prefrontal cortex pathology and in therapeutic response to atypical antipsychotics...
  73. ncbi One-year treatment of Alzheimer's disease with acetylcholinesterase inhibitors: improvement on ADAS-cog and TMT A, no change or worsening on other tests
    Alina Borkowska
    Clinical Neuropsychology Unit, Nicolaus Copernicus University, Torun, Collegium Medicum, Bydgoszcz, Poland
    Hum Psychopharmacol 20:409-14. 2005
    ....
  74. doi Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial
    Rene S Kahn
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, Netherlands
    Lancet 371:1085-97. 2008
    ..We aimed to compare the effectiveness of second-generation antipsychotic drugs with that of a low dose of haloperidol, in first-episode schizophrenia...
  75. ncbi Two generations of mood stabilizers
    Janusz K Rybakowski
    Int J Neuropsychopharmacol 10:709-11. 2007
  76. ncbi Aripiprazole joins the family of second-generation mood stabilizers
    Janusz K Rybakowski
    J Clin Psychiatry 69:862-3. 2008