Lech Zwierzchowski

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. ncbi request reprint A LINE-1 element insertion in the 5'-noncoding region of caprine growth hormone receptor gene
    Andrzej Maj
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552, Wolka Kosowska, Poland
    Biochem Genet 43:465-70. 2005
  2. doi request reprint Association of polymorphisms in exons 2 and 10 of the insulin-like growth factor 2 ( IGF2) gene with milk production traits in Polish Holstein-Friesian cattle
    Emilia Bagnicka
    Institute of Genetics and Animal Breeding Polish Academy of Sciences, Jastrzebiec, Poland
    J Dairy Res 77:37-42. 2010
  3. ncbi request reprint Polymorphism in genes of growth hormone receptor (GHR) and insulin-like growth factor-1 (IGF1) and its association with both the IGF1 expression in liver and its level in blood in Polish Holstein-Friesian cattle
    Andrzej Maj
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 29:981-9. 2008
  4. ncbi request reprint Single base substitution in growth hormone receptor gene influences the receptor density in bovine liver
    Andrzej Maj
    Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 28:401-5. 2007
  5. doi request reprint Defensins: Natural component of human innate immunity
    Justyna Jarczak
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences in Jastrzebiec, Poland
    Hum Immunol 74:1069-79. 2013
  6. ncbi request reprint Expression in promoter variant of the ERalpha gene in bos taurus liver
    Tomasz Szreder
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552, Wolka Kosowska, Poland
    Mol Biol Rep 35:65-71. 2008
  7. doi request reprint Effect of the g.-723G-->T polymorphism in the bovine myogenic factor 5 (Myf5) gene promoter region on gene transcript level in the longissimus dorsi muscle and on meat traits of Polish Holstein-Friesian cattle
    Dagmara Robakowska-Hyzorek
    Institute of Genetics and Animal Breeding, Wolka Kosowska, Poland
    Biochem Genet 48:450-64. 2010
  8. ncbi request reprint Development of real-time PCR assays in the study of gonadotropin subunits, follistatin and prolactin genes expression in the porcine anterior pituitary during the preovulatory period
    Pawel Lisowski
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 29:958-64. 2008
  9. ncbi request reprint Estrogen receptors and their genes--potential markers of functional and production traits of farm animals
    Tomasz Szreder
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Mol Biol Rep 34:207-11. 2007
  10. pmc Cathelicidins: family of antimicrobial peptides. A review
    Ewa M Kościuczuk
    Institute of Genetics and Animal Breeding in Jastrzębiec, Polish Academy of Sciences, 05 552, Magdalenka, Poland
    Mol Biol Rep 39:10957-70. 2012

Collaborators

  • Pawel Lisowski
  • Krzysztof Flisikowski
  • Kazimierz Kochman
  • Artur H Swiergiel
  • Monika M Kaczmarek
  • S Hiendleder
  • Chandra S Pareek
  • Andrzej Maj
  • Emilia Bagnicka
  • Tomasz Szreder
  • Józef Krzyżewski
  • Nina Strzałkowska
  • Jolanta Oprzadek
  • Justyna Jarczak
  • Ewa M Kościuczuk
  • Artur Jóźwik
  • Jarosław Horbańczuk
  • Dagmara Robakowska-Hyzorek
  • Beata Zelazowska
  • Eulalia Siadkowska
  • Tomasz Sadkowski
  • Alexei A Sazanov
  • Tatiana Adamowicz
  • Patrice Martin
  • Rafał Olbromski
  • Michał Jank
  • Tomasz Motyl
  • Renata Grochowska
  • Marek Snochowski
  • Barbara Rowinska
  • Mariusz Pierzchala
  • Alina Gajewska
  • Stanisław Kaminski
  • Tadeusz Malewski
  • Rafał Starzyński
  • Marek Switonski
  • Małgorzata Szymanowska
  • Christine Leroux

Detail Information

Publications25

  1. ncbi request reprint A LINE-1 element insertion in the 5'-noncoding region of caprine growth hormone receptor gene
    Andrzej Maj
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552, Wolka Kosowska, Poland
    Biochem Genet 43:465-70. 2005
  2. doi request reprint Association of polymorphisms in exons 2 and 10 of the insulin-like growth factor 2 ( IGF2) gene with milk production traits in Polish Holstein-Friesian cattle
    Emilia Bagnicka
    Institute of Genetics and Animal Breeding Polish Academy of Sciences, Jastrzebiec, Poland
    J Dairy Res 77:37-42. 2010
    ..001). The most frequent CT/GG haplotype seemed inferior to others in fat and protein content and daily yield of fat and protein but superior (together with the TT/GG genotype) when the daily milk yield is considered...
  3. ncbi request reprint Polymorphism in genes of growth hormone receptor (GHR) and insulin-like growth factor-1 (IGF1) and its association with both the IGF1 expression in liver and its level in blood in Polish Holstein-Friesian cattle
    Andrzej Maj
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 29:981-9. 2008
    ..The objective of this study was to examine the effects of polymorphisms in 5'-regions of the bovine ghr and igf1 genes on the igf1 gene expression in the liver and on the level of IGF1 in blood of Polish Holstein-Friesian cattle...
  4. ncbi request reprint Single base substitution in growth hormone receptor gene influences the receptor density in bovine liver
    Andrzej Maj
    Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 28:401-5. 2007
    ..We searched for the relationship between the A/T nucleotide polymorphism in the GHR gene the receptor binding capacity and dissociation constant...
  5. doi request reprint Defensins: Natural component of human innate immunity
    Justyna Jarczak
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences in Jastrzebiec, Poland
    Hum Immunol 74:1069-79. 2013
    ....
  6. ncbi request reprint Expression in promoter variant of the ERalpha gene in bos taurus liver
    Tomasz Szreder
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552, Wolka Kosowska, Poland
    Mol Biol Rep 35:65-71. 2008
    ..As shown by Real-Time PCR, on the livers of animals with different genotype ERalpha mRNA for BglI polymorphism we didn't found variability, but for SnaBI we have found variability between AG and AA genotypes...
  7. doi request reprint Effect of the g.-723G-->T polymorphism in the bovine myogenic factor 5 (Myf5) gene promoter region on gene transcript level in the longissimus dorsi muscle and on meat traits of Polish Holstein-Friesian cattle
    Dagmara Robakowska-Hyzorek
    Institute of Genetics and Animal Breeding, Wolka Kosowska, Poland
    Biochem Genet 48:450-64. 2010
    ..This polymorphism showed an influence on Myf5 gene expression in the longissimus dorsi muscle and was associated with sirloin weight and fat weight in sirloin in carcasses of Holstein-Friesian cattle...
  8. ncbi request reprint Development of real-time PCR assays in the study of gonadotropin subunits, follistatin and prolactin genes expression in the porcine anterior pituitary during the preovulatory period
    Pawel Lisowski
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Neuro Endocrinol Lett 29:958-64. 2008
    ..Moreover, we focused on the influence of GnRH receptor antagonist (antide) treatment on mRNA expression levels of GPalpha, LHbeta, FSHbeta, FST(follistatin) and PRL(prolactin) genes in these cells...
  9. ncbi request reprint Estrogen receptors and their genes--potential markers of functional and production traits of farm animals
    Tomasz Szreder
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Mol Biol Rep 34:207-11. 2007
    ..Moreover, we found several polymorphic sites, differing by single nucleotide substitutions (SNPs), in the 5' regulatory region and in the coding region of the bovine ERalpha gene...
  10. pmc Cathelicidins: family of antimicrobial peptides. A review
    Ewa M Kościuczuk
    Institute of Genetics and Animal Breeding in Jastrzębiec, Polish Academy of Sciences, 05 552, Magdalenka, Poland
    Mol Biol Rep 39:10957-70. 2012
    ..The aim of the present review is to summarize current information about these antimicrobial peptides in farm animals, highlighting peptide expression sites, activities, and future applications for human and veterinary medicine...
  11. pmc Effects of chronic stress on prefrontal cortex transcriptome in mice displaying different genetic backgrounds
    Pawel Lisowski
    Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Postepu 1, 05 552 Jastrzebiec n Warsaw, Warsaw, Poland
    J Mol Neurosci 50:33-57. 2013
    ..The results indicate significant contribution of genetic background to differences in stress response gene expression in the mouse prefrontal cortex...
  12. doi request reprint Evaluation of reference genes for studies of gene expression in the bovine liver, kidney, pituitary, and thyroid
    Paweł Lisowski
    Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Poland
    J Appl Genet 49:367-72. 2008
    ....
  13. doi request reprint Selection for stress-induced analgesia affects the mouse hippocampal transcriptome
    Pawel Lisowski
    Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Poland
    J Mol Neurosci 47:101-12. 2012
    ..The results suggest that individual stress responsiveness may be associated with characteristics of the constitutive hippocampal transcriptome...
  14. ncbi request reprint Nucleotide sequence and variation of IGF2 gene exon 6 in Bos taurus and Bos indicus cattle
    Krzysztof Flisikowski
    Institute of Genetics and Animal Breeding, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Anim Biotechnol 16:203-8. 2005
    ..A comparative analysis was performed for this fragment from different species; 99.5% identity was found between Bos taurus and Bos indicus cattle...
  15. ncbi request reprint Molecular evolution of coding and non-coding sequences of the growth hormone receptor (GHR) gene in the family Bovidae
    Andrzej Maj
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Folia Biol (Krakow) 54:31-6. 2006
    ..0513/100 bp/MY for the Bovidae GHR gene exons 1A and 4, respectively. Thus, the GHR gene is well conserved in the Bovidae family. Also, in this study some novel intraspecies polymorphisms were found for cattle and sheep...
  16. ncbi request reprint Expression and polymorphism of defensins in farm animals
    Emilia Bagnicka
    Institute of Genetics and Animal Breeding in Jastrzębiec, Polish Academy of Sciences, Wolka Kosowska, Poland
    Acta Biochim Pol 57:487-97. 2010
    ....
  17. doi request reprint Effect of chronic mild stress on hippocampal transcriptome in mice selected for high and low stress-induced analgesia and displaying different emotional behaviors
    Pawel Lisowski
    Department of Molecular Biology, Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Poland
    Eur Neuropsychopharmacol 21:45-62. 2011
    ....
  18. ncbi request reprint Promoter variant-dependent expression of the STAT5A gene in bovine liver
    Krzysztof Flisikowski
    Department of Molecular Biology, Institute of Genetics and Animal Breeding Polish Academy of Sciences, Postepu 1, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Biochim Biophys Acta 1679:195-9. 2004
    ..Electrophoretic mobility shift assay (EMSA) showed that the A-->G transition at position -488 increased the STAT5A gene promoter binding capacity for liver nuclear proteins [possibly hepatic nuclear factor (HNF)-3]...
  19. ncbi request reprint Polymorphism within the bovine estrogen receptor-alpha gene 5'-region
    Tomasz Szreder
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, Wolka Kosowska, Poland
    J Appl Genet 45:225-36. 2004
    ..A polymorphism within the 5' region of the bovine ERalpha gene-A/G transition, which could be recognized with RFLP-BglI, lying upstream to the exon C, was identified for the first time using this sequence...
  20. ncbi request reprint Polymerase chain reaction-heteroduplex (PCR-HD) polymorphism within the bovine STAT5A gene
    Krzysztof Flisikowski
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    J Appl Genet 44:185-9. 2003
    ..The frequency of allele A varied between 0.91 and 0.77. Animals of genotype BB were found in Charolaise and Limousine breeds only...
  21. ncbi request reprint The DNA-binding capacity of genetic variants of the bovine STAT5A transcription factor
    Krzysztof Flisikowski
    Institute of Genetics and Animal Breeding, Polish Academy of Sciences, Jastrzebiec, 05 552 Wolka Kosowska, Poland
    Cell Mol Biol Lett 8:831-40. 2003
    ..EMSA competition experiments confirmed that STAT5 transcription factors take part in the formation of the DNA-protein complexes...
  22. doi request reprint Gene expression profiling in skeletal muscle of Holstein-Friesian bulls with single-nucleotide polymorphism in the myostatin gene 5'-flanking region
    Tomasz Sadkowski
    Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences SGGW, Warsaw, Poland
    J Appl Genet 49:237-50. 2008
    ....
  23. ncbi request reprint Characterization of the CHORI-240 BAC clones containing the bovine CSN1S1, CSN2, STATH, CSN1S2 and CSN3 genes
    Alexei A Sazanov
    Laboratory of Molecular Genome Organization, Institute of Farm Animal Genetics and Breeding, Russian Academy of Agricultural Sciences, Moskovskoye sh St Petersburg Pushkin, Russia
    J Appl Genet 47:243-5. 2006
    ..These data showed that the BAC contig was established for the whole casein cluster, including all known five genes...
  24. ncbi request reprint Mutation in the Sp1 motif of the bovine leptin gene affects its expression
    Tatiana Adamowicz
    Department of Genetics and Animal Breeding, Agricultural University of Poznan, Poznan, Poland
    Mamm Genome 17:77-82. 2006
    ..With real-time PCR and Western blotting, we showed that the leptin expression level was higher in cattle with the CC than with the GG genotype...
  25. ncbi request reprint The impact of genetic polymorphisms on the protein composition of ruminant milks
    Patrice Martin
    Institut National de la Recherche Agronomique, Laboratoire de Génétique Biochimique et de Cytogénétique, bâtiment Jacques Poly, Centre de Jouy, 78352 Jouy en Josas, France
    Reprod Nutr Dev 42:433-59. 2002
    ....