Jan Wrzesinski

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. doi request reprint Mapping the interactions of selected antibiotics and their Cu(2+) complexes with the antigenomic delta ribozyme
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61 704 Poznan, Poland
    FEBS J 280:2652-64. 2013
  2. ncbi request reprint Characterization of structure and metal ions specificity of Co2+-binding RNA aptamers
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Biochemistry 44:6257-68. 2005
  3. ncbi request reprint Inhibition of the catalytic activity of trans-acting antigenomic delta ribozyme by selected antibiotics and their Cu2+ complexes
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Biochem Biophys Res Commun 349:1394-400. 2006
  4. doi request reprint Structural basis for recognition of Co2+ by RNA aptamers
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, Poznan, Poland
    FEBS J 275:1651-62. 2008
  5. doi request reprint Capreomycin and hygromycin B modulate the catalytic activity of the delta ribozyme in a manner that depends on the protonation and complexation with Cu2+ ions of these antibiotics
    Milena Szafraniec
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Dalton Trans 41:9728-36. 2012
  6. ncbi request reprint DNA and RNA damage by Cu(II)-amikacin complex
    Małgorzata Jeżowska-Bojczuk
    Faculty of Chemistry, University of Wrocław, Wrocław, Poland Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Eur J Biochem 269:5547-56. 2002
  7. ncbi request reprint tRNAPhe cleavage by aminoglycosides is triggered off by formation of an abasic site
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Biochem Biophys Res Commun 331:267-71. 2005
  8. doi request reprint Trans-acting antigenomic HDV ribozyme for production of in vitro transcripts with homogenous 3' ends
    Milena Szafraniec
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Methods Mol Biol 941:99-111. 2012
  9. doi request reprint Selection of RNA oligonucleotides that can modulate human dicer activity in vitro
    Agata Tyczewska
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Nucleic Acid Ther 21:333-46. 2011
  10. ncbi request reprint Translational and structural analysis of the shortest legume ENOD40 gene in Lupinus luteus
    Jan Podkowinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Acta Biochim Pol 56:89-102. 2009

Collaborators

Detail Information

Publications10

  1. doi request reprint Mapping the interactions of selected antibiotics and their Cu(2+) complexes with the antigenomic delta ribozyme
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61 704 Poznan, Poland
    FEBS J 280:2652-64. 2013
    ....
  2. ncbi request reprint Characterization of structure and metal ions specificity of Co2+-binding RNA aptamers
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Biochemistry 44:6257-68. 2005
    ..Among many factors that influence metal specificity of the Co(2+)-binding pocket, chemical properties of metal ions, such as their hardness as well as the structure of the coordination site, seem to be particularly important...
  3. ncbi request reprint Inhibition of the catalytic activity of trans-acting antigenomic delta ribozyme by selected antibiotics and their Cu2+ complexes
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Biochem Biophys Res Commun 349:1394-400. 2006
    ..These observations indicate that coordination of metal ions to antibiotics substantially changes their properties which might also have a biological relevance inside the cell...
  4. doi request reprint Structural basis for recognition of Co2+ by RNA aptamers
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, Poznan, Poland
    FEBS J 275:1651-62. 2008
    ....
  5. doi request reprint Capreomycin and hygromycin B modulate the catalytic activity of the delta ribozyme in a manner that depends on the protonation and complexation with Cu2+ ions of these antibiotics
    Milena Szafraniec
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Dalton Trans 41:9728-36. 2012
    ..Possibly, the amino functions of these antibiotics might be involved in a general acid-base catalysis performed by the ribozyme, acting as proton acceptors/donors...
  6. ncbi request reprint DNA and RNA damage by Cu(II)-amikacin complex
    Małgorzata Jeżowska-Bojczuk
    Faculty of Chemistry, University of Wrocław, Wrocław, Poland Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Eur J Biochem 269:5547-56. 2002
    ..The complex underwent autooxidation as well, with amikacin hydroperoxides as likely major products. This reactivity pattern was found to be due to a combination of metal-bound and free hydroxyl radicals...
  7. ncbi request reprint tRNAPhe cleavage by aminoglycosides is triggered off by formation of an abasic site
    Jan Wrzesinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12 14, 61 704 Poznan, Poland
    Biochem Biophys Res Commun 331:267-71. 2005
    ..The results suggest that the phenomenon, previously considered as selective with respect to the presence of tRNA hypermodification, may concern far more RNA molecules, namely the ones carrying abasic sites...
  8. doi request reprint Trans-acting antigenomic HDV ribozyme for production of in vitro transcripts with homogenous 3' ends
    Milena Szafraniec
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Methods Mol Biol 941:99-111. 2012
    ..The highest concentration of RNA substrate suggested for practical applications turns out to be 3 μM. The procedure is an alternative to the use of ribozymes as cis-cleaving autocatalytic cassettes attached to transcript 3' ends...
  9. doi request reprint Selection of RNA oligonucleotides that can modulate human dicer activity in vitro
    Agata Tyczewska
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Nucleic Acid Ther 21:333-46. 2011
    ..Moreover, we found that sequences similar to those of the selected oligomers can be found within the molecules composing human transcriptome...
  10. ncbi request reprint Translational and structural analysis of the shortest legume ENOD40 gene in Lupinus luteus
    Jan Podkowinski
    Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland
    Acta Biochim Pol 56:89-102. 2009
    ..The differences between L. luteus and Glycine max ENOD40 RNA models suggest the possibility of a switch between two structural states of ENOD40 transcript...