A Slowik

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. ncbi request reprint DD genotype of ACE gene is a risk factor for intracerebral hemorrhage
    A Slowik
    Department of Neurology, Jagiellonian University, Medical College, 31 503 Krakow, Botaniczna 3, Poland
    Neurology 63:359-61. 2004
  2. ncbi request reprint Stroke attack rates and case fatality in the Krakow Stroke Registry
    Agnieszka Słowik
    Department of Neurology, Jagiellonian University College of Medicine, ul Botaniczna 3, 31 503 Krakow, Poland
    Neurol Neurochir Pol 41:291-5. 2007
  3. ncbi request reprint II genotype of the angiotensin-converting enzyme gene increases the risk for subarachnoid hemorrhage from ruptured aneurysm
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, 31 503 Krakow, Botaniczna 3, Poland
    Stroke 35:1594-7. 2004
  4. ncbi request reprint A2 alelle of GpIIIa gene is a risk factor for stroke caused by large-vessel disease in males
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, 31 503 Krakow, Botaniczna 3, Poland
    Stroke 35:1589-93. 2004
  5. ncbi request reprint LDL phenotype B and other lipid abnormalities in patients with large vessel disease and small vessel disease
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University College of Medicine, ul Botaniczna 3, Cracow 31 503, Poland
    J Neurol Sci 214:11-6. 2003
  6. ncbi request reprint Alpha1-antichymotrypsin gene (SERPINA3) A/T polymorphism as a risk factor for aneurysmal subarachnoid hemorrhage
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Stroke 36:737-40. 2005
  7. ncbi request reprint [Whipple's disease--a rare cause of neurological symptoms and disorders]
    Agnieszka Słowik
    Kliniki Neurologii Collegium Medicum, Uniwersytet Jagiellonski
    Neurol Neurochir Pol 36:959-70. 2002
  8. ncbi request reprint [The diagnosis of subclinical hepatic encephalopathy]
    A Słowik
    Klinika Neurologii, Collegium Medicum, Uniwersytet Jagiellonski, Krakow
    Przegl Lek 58:1059-62. 2001
  9. ncbi request reprint Hypercortisolemia in acute stroke is related to the inflammatory response
    Agnieszka Slowik
    Stroke Unit, Department of Neurology, Collegium Medicum, Jagiellonian University, Botaniczna 3 31 503, Krakow, Poland
    J Neurol Sci 196:27-32. 2002
  10. ncbi request reprint Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Cerebrovasc Dis 23:395-400. 2007

Collaborators

Detail Information

Publications45

  1. ncbi request reprint DD genotype of ACE gene is a risk factor for intracerebral hemorrhage
    A Slowik
    Department of Neurology, Jagiellonian University, Medical College, 31 503 Krakow, Botaniczna 3, Poland
    Neurology 63:359-61. 2004
    ..The authors report evidence that ACE gene DD homozygosity of the I/D polymorphism in intron 16 is an independent risk factor for SIH, and not for SVD stroke, in a Polish population...
  2. ncbi request reprint Stroke attack rates and case fatality in the Krakow Stroke Registry
    Agnieszka Słowik
    Department of Neurology, Jagiellonian University College of Medicine, ul Botaniczna 3, 31 503 Krakow, Poland
    Neurol Neurochir Pol 41:291-5. 2007
    ..We used the data of the Krakow Stroke Registry to calculate the attack rates as well as short- and long-term case fatality rates from stroke in hospitalized inhabitants of Krakow, Poland...
  3. ncbi request reprint II genotype of the angiotensin-converting enzyme gene increases the risk for subarachnoid hemorrhage from ruptured aneurysm
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, 31 503 Krakow, Botaniczna 3, Poland
    Stroke 35:1594-7. 2004
    ..The aim of this study was to investigate the association between ACE I/D polymorphism and a risk for aneurysmal SAH in a Polish population...
  4. ncbi request reprint A2 alelle of GpIIIa gene is a risk factor for stroke caused by large-vessel disease in males
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, 31 503 Krakow, Botaniczna 3, Poland
    Stroke 35:1589-93. 2004
    ..We studied the significance of the GpIIIa gene A1/A2 polymorphism in stroke patients with different stroke causes...
  5. ncbi request reprint LDL phenotype B and other lipid abnormalities in patients with large vessel disease and small vessel disease
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University College of Medicine, ul Botaniczna 3, Cracow 31 503, Poland
    J Neurol Sci 214:11-6. 2003
    ..We investigated the prevalence of LDL phenotype B and other lipid abnormalities in stroke survivors with large vessel disease (LVD) or small vessel disease (SVD) (TOAST criteria) and in control subjects (CS)...
  6. ncbi request reprint Alpha1-antichymotrypsin gene (SERPINA3) A/T polymorphism as a risk factor for aneurysmal subarachnoid hemorrhage
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Stroke 36:737-40. 2005
    ..We studied the significance of SERPINA3 A/T polymorphism in patients with aneurysmal SAH compared with healthy controls...
  7. ncbi request reprint [Whipple's disease--a rare cause of neurological symptoms and disorders]
    Agnieszka Słowik
    Kliniki Neurologii Collegium Medicum, Uniwersytet Jagiellonski
    Neurol Neurochir Pol 36:959-70. 2002
    ..Whipple's disease is potentially fatal but responds to antibiotic treatment. The current recommendations for treatment are discussed...
  8. ncbi request reprint [The diagnosis of subclinical hepatic encephalopathy]
    A Słowik
    Klinika Neurologii, Collegium Medicum, Uniwersytet Jagiellonski, Krakow
    Przegl Lek 58:1059-62. 2001
    ....
  9. ncbi request reprint Hypercortisolemia in acute stroke is related to the inflammatory response
    Agnieszka Slowik
    Stroke Unit, Department of Neurology, Collegium Medicum, Jagiellonian University, Botaniczna 3 31 503, Krakow, Poland
    J Neurol Sci 196:27-32. 2002
    ..Prognostic significance of hypercortisolemia in acute stroke patients seems to be related to the inflammatory response rather than to the stress response...
  10. ncbi request reprint Paraoxonase 2 gene C311S polymorphism is associated with a risk of large vessel disease stroke in a Polish population
    Agnieszka Slowik
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Cerebrovasc Dis 23:395-400. 2007
    ..We studied the significance of the Q192R and M55L polymorphisms of the PON1 gene and the C311S polymorphism of the PON2 gene in different etiologies of ischemic stroke...
  11. ncbi request reprint Paraoxonase gene polymorphism and the risk for Alzheimer's disease in the polish population
    A Klimkowicz-Mrowiec
    Department of Neurology, School of Medicine, Jagiellonian University, ul Botaniczna 3, Cracow, Poland
    Dement Geriatr Cogn Disord 31:417-23. 2011
    ..The relationship between different paraoxonase (PON) gene polymorphisms and the risk of Alzheimer's disease (AD) was studied several times and the results were controversial...
  12. ncbi request reprint Paraoxonase gene polymorphisms and sporadic ALS
    A Slowik
    Department of Neurology, Jagiellonian University, Botaniczna 3, 31 503 Krakow, Poland
    Neurology 67:766-70. 2006
    ..Chronic exposure to certain chemicals or to environmental factors causing enhanced lipid peroxidation metabolized by paraoxonases may be a risk factor for sporadic ALS (sALS)...
  13. ncbi request reprint ACE I/D polymorphism in different etiologies of ischemic stroke
    J Pera
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Acta Neurol Scand 114:320-2. 2006
    ..Results of some studies suggest that DD genotype may be a risk factor for small vessel disease (SVD) stroke. Here, we investigated whether this polymorphism is associated with IS of different etiologies in a Polish population...
  14. ncbi request reprint Transient hyperglycemia in ischemic stroke patients
    A Szczudlik
    Stroke Unit, Department of Neurology, Collegium Medicum, Jagiellonian University, ul Botaniczna 3, 31 503 Cracow, Poland
    J Neurol Sci 189:105-11. 2001
    ..05). A proportional hazards model analysis showed that transient hyperglycemia is not an independent predictor of death within a year after stroke...
  15. ncbi request reprint Serum interleukin-6 predicts cortisol release in acute stroke patients
    A Szczudlik
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    J Endocrinol Invest 27:37-41. 2004
    ..In conclusion, brain ischemia could stimulate IL-6 release in blood and in this way modulate hypothalamo-pituitary-adrenal axis...
  16. ncbi request reprint Serum albumin level and nosocomial pneumonia in stroke patients
    T Dziedzic
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Eur J Neurol 13:299-301. 2006
    ..9 g/l) and serum albumin level was associated with risk of pneumonia on multivariate analysis (OR: 0.95, 95% CI: 0.91-0.98). Our results show that serum albumin level is an independent predictor of nosocomial pneumonia in stroke patients...
  17. ncbi request reprint Hypoalbuminemia in acute ischemic stroke patients: frequency and correlates
    T Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Eur J Clin Nutr 61:1318-22. 2007
    ..The aim of our study was to determine the frequency and correlates of hypoalbuminemia in unselected cohort of patients with acute cerebral infarction...
  18. doi request reprint Interleukin-1 gene -511 CT polymorphism and the risk of Alzheimer's disease in a Polish population
    A Klimkowicz-Mrowiec
    Department of Neurology, University Hospital, Cracow, Poland
    Dement Geriatr Cogn Disord 28:461-4. 2009
    ..60, 95% confidence interval 4.19-10.41). APOE status did not affect the distribution of the studied IL-1beta polymorphism. The IL-1beta (-511 C/T) polymorphism is not a risk factor for late-onset AD in a Polish population...
  19. doi request reprint A1/A2 polymorphism of GpIIIa gene and a risk of aneurysmal subarachnoid haemorrhage
    Mateusz G Adamski
    Department of Neurology, Jagiellonian University Medical College, Krakow, Poland
    Biochem Biophys Res Commun 383:228-30. 2009
    ..048-7.478) and smoking (OR=2.034; 95%CI: 1.366-3.030), but not GpIIIa A1/A2 polymorphism, were independent risk factors for aneurysmal SAH. The GpIIIa A1/A2 polymorphism is not a risk factor of aneurysmal SAH in a Polish population...
  20. doi request reprint Interleukin 6-174G>C polymorphism and risk of aneurysmal subarachnoid hemorrhage: case-control study and meta-analysis
    J Pera
    Department of Neurology, Jagiellonian University Medical College, Krakow, Poland
    Acta Neurol Scand 125:111-5. 2012
    ..The aim of this study was to investigate whether this IL6 polymorphism is associated with aSAH in a Polish population...
  21. doi request reprint A-G-4G haplotype of PAI-1 gene polymorphisms -844 G/A, HindIII G/C, and -675 4G/5G is associated with increased risk of ischemic stroke caused by small vessel disease
    M G Adamski
    Department of Neurology, Jagiellonian University Medical College, Krakow, Poland
    Acta Neurol Scand 120:94-100. 2009
    ..We studied the association of three common polymorphisms in PAI-1 gene (-844 G/A, -675 4G/5G, and HindIII G/C) with the odds of different causes of ischemic stroke...
  22. doi request reprint Gene expression profiles in human ruptured and unruptured intracranial aneurysms: what is the role of inflammation?
    Joanna Pera
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Stroke 41:224-31. 2010
    ..The majority of studies on human tissue have focused on predefined pathways. We sought to analyze global gene expression patterns of ruptured IA, unruptured IA, and control vessels...
  23. ncbi request reprint Beta-blockers reduce the risk of early death in ischemic stroke
    Tomasz Dziedzic
    Department of Neurology, Jagiellonian University, Botaniczna 3, 31 503 Krakow, Poland
    J Neurol Sci 252:53-6. 2007
    ..Experimental studies suggest that beta-blockers have also neuroprotective properties. The aim of this study was to assess if use of beta-blockers is associated with reduced risk of early death in ischemic stroke patients...
  24. doi request reprint The impact of postadmission glycemia on stroke outcome: Glucose normalisation is associated with better survival
    Tomasz Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, 31 503 Krakow, ul Botaniczna 3, Krakow, Poland
    Atherosclerosis 211:584-8. 2010
    ..The goal of the study was to determine the relationship between postadmission glucose levels and mortality in stroke patients with and without admission hyperglycemia...
  25. ncbi request reprint Endoglin gene insertion polymorphism not associated with aneurysmal subarachnoid hemorrhage
    Joanna Pera
    Department of Neurology, Jagiellonian University, Krakow, Poland
    J Neurosurg 102:879-81. 2005
    ..In this study the authors investigated whether this polymorphism is associated with a subarachnoid hemorrhage (SAH) caused by a ruptured IA in a Polish population...
  26. doi request reprint Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage
    Joanna Pera
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Cerebrovasc Dis 25:445-9. 2008
    ..Glutathione peroxidase 1 (GPX1) is a key enzyme of the antioxidant system. Here, we investigated whether a functional C593T polymorphism of GPX1 gene is associated with PICH in a Polish population...
  27. ncbi request reprint SERPINA3 polymorphism is not associated with primary intracerebral hemorrhage in a Polish population
    Joanna Pera
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Stroke 37:906-7. 2006
    ..The aim of the present study was to investigate whether SERPINA3 A/T polymorphism is associated with PICH in a Polish population...
  28. ncbi request reprint Intracerebral hemorrhage triggers interleukin-6 and interleukin-10 release in blood
    Tomasz Dziedzic
    Stroke Unit, Department of Neurology, and Second Department of Cardiology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Stroke 33:2334-5. 2002
    ..The goal of this study was to determine the serum level of interleukin-6, interleukin-10, and interleukin-13 in patients with intracerebral hemorrhage and to correlate cytokine concentrations with stroke severity...
  29. ncbi request reprint Dexamethasone inhibits TNF-alpha synthesis more effectively in Alzheimer's disease patients than in healthy individuals
    Tomasz Dziedzic
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Dement Geriatr Cogn Disord 16:283-6. 2003
    ..These results suggest that cytokine synthesis in AD patients could be regulated by glucocorticoids in a different way than in nondemented subjects...
  30. ncbi request reprint Urine albumin excretion in acute ischaemic stroke is related to serum interleukin-6
    Tomasz Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Clin Chem Lab Med 42:182-5. 2004
    ..The goal of this study was to determine if there is a relationship between urine albumin excretion and interleukin-6, a key mediator of acute phase reaction...
  31. ncbi request reprint Lower serum triglyceride level is associated with increased stroke severity
    Tomasz Dziedzic
    Department of Neurology, Jagiellonian University, Botaniczna 3, 31 503 Krakow, Poland
    Stroke 35:e151-2. 2004
    ..A previous study showed that low triglyceride concentration predicts higher mortality after stroke. The aim of our study was to determine whether serum triglyceride level is associated with stroke severity on admission...
  32. ncbi request reprint Coagulation factor XIII VaI34Leu polymorphism in patients with small vessel disease or primary intracerebral hemorrhage
    Agnieszka Slowik
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Cerebrovasc Dis 19:165-70. 2005
    ..The aim of the study was to investigate the association between the FXIII Val34Leu polymorphism and the risk of ischemic stroke due to small vessel disease (SVD) or the risk of primary intracerebral hemorrhage (PICH)...
  33. ncbi request reprint [Plasma homocysteine concentration in patients with ischaemic stroke caused by large or small vessel disease]
    Wojciech Turaj
    Jagiellonian University, Medical College, Department of Neurology, Krakow, Poland
    Pol Merkur Lekarski 26:121-4. 2009
    ..Homocysteine is known risk factor for the development of atherosclerosis, but its contribution to the different etiologies of ischaemic stroke remains unclear...
  34. ncbi request reprint Interleukin 1 beta polymorphism (-511) and risk of stroke due to small vessel disease
    Tomasz Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Cerebrovasc Dis 20:299-303. 2005
    ..The aim of this study was to investigate the association between the IL-1beta gene polymorphism (-511) and the risk of large vessel disease (LVD) stroke, small vessel disease (SVD) stroke and cardioembolic (CE) stroke...
  35. doi request reprint Association between hyperglycemia, heart failure and mortality in stroke patients
    T Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    Eur J Neurol 16:251-6. 2009
    ..The aim of our study was to determine if acute stroke patients with hyperglycemia suffer from increased rate of in-hospital adverse events which could influence survival such as pneumonia, heart failure and myocardial infarction...
  36. ncbi request reprint Asymmetrical modulation of interleukin-10 release in patients with intracerebral hemorrhage
    Tomasz Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, 31 503 Krakow, ul Botaniczna 3, Poland
    Brain Behav Immun 17:438-41. 2003
    ..These results suggest that left and right hemisphere could modulate IL-10 release in different way...
  37. ncbi request reprint Inducible nitric oxide production and expression of transforming growth factor-beta1 in serum and CSF after cerebral ischaemic stroke in man
    J Krupinski
    Department of Neurology, Institute of Neurology, Jagiellonian University, Cracow, Poland
    Nitric Oxide 2:442-53. 1998
    ..These findings suggest that the interaction between TGF-beta1 and NOS2 might be important for angiogenesis after cerebral ischaemia and may indicate that TGF-beta1 is upregulated as a negative feedback response to elevated levels of NO...
  38. ncbi request reprint Serum albumin level as a predictor of ischemic stroke outcome
    Tomasz Dziedzic
    Department of Neurology, Jagiellonian University, Krakow, Poland
    Stroke 35:e156-8. 2004
    ..The aim of our study was to determine if relatively high serum albumin level is associated with decreased risk of poor outcome in ischemic stroke patients...
  39. ncbi request reprint Serum interleukin-6 soluble receptor in relation to interleukin-6 in stroke patients
    Tomasz Dziedzic
    Department of Neurology, Collegium Medicum, Jagiellonian University, Krakow, Poland
    J Mol Neurosci 24:293-8. 2004
    ..Decreased sIL-6R early after stroke might reflect a regulatory mechanism attenuating inflammatory response...
  40. ncbi request reprint Incidence of pre- and poststroke dementia: cracow stroke registry
    Aleksandra Klimkowicz
    Stroke Unit, Department of Neurology, Jagiellonian University, Cracow, Poland
    Dement Geriatr Cogn Disord 14:137-40. 2002
    ..When we excluded the patients with recurrent stroke, the incidence of pre- and poststroke dementia was 9.3 and 21.2%, respectively. Conclusion: About one tenth of stroke patients have preexisting dementia...
  41. doi request reprint Severity of explicit memory impairment due to Alzheimer's disease improves effectiveness of implicit learning
    Aleksandra Klimkowicz-Mrowiec
    Dept of Neurology, College of Medicine, Jagiellonian University, Botaniczna 3, 31 503 Cracow, Poland
    J Neurol 255:502-9. 2008
    ..According to data from some studies, explicit memory seems to exhibit no influence on implicit memory,whereas the other studies indicate that explicit memory may inhibit or facilitate implicit memory...
  42. ncbi request reprint Is mannitol safe for patients with intracerebral hemorrhages? Renal considerations
    Tomasz Dziedzic
    Department of Neurology, Stroke Unit, Jagiellonian University, 31 503 Krakow, ul Botaniczna 3, Poland
    Clin Neurol Neurosurg 105:87-9. 2003
    ..Mannitol, a drug widely used to decrease intracranial pressure, can cause renal failure. The goal of this study is to determine the renal safety of mannitol therapy in patients with intraparenchymal hemorrhages...
  43. ncbi request reprint Reduced prefrontal N-acetylaspartate in stroke patients with apathy
    Lidia Glodzik-Sobanska
    Center for Brain Health, NYU School of Medicine, 550 First Avenue, HN 400, NY 10016 6481, USA
    J Neurol Sci 238:19-24. 2005
    ..Our aim was to investigate the association between proton magnetic resonance spectroscopy (H1-MRS) measurements in unaffected frontal lobes and apathy in a group of first-time stroke patients...
  44. ncbi request reprint Interleukin-6 and stroke: cerebral ischemia versus nonspecific factors influencing interleukin-6
    Tomasz Dziedzic
    Stroke 34:e229-30; author reply e229-30. 2003
  45. ncbi request reprint Single voxel proton magnetic resonance spectroscopy in post-stroke depression
    Lidia Glodzik-Sobanska
    Center for Brain Health, New York University School of Medicine, New York, NY 10016, USA
    Psychiatry Res 148:111-20. 2006
    ..These findings suggest that post-stroke depression is accompanied by changes in frontal lobe glutamate/glutamine levels, perhaps reflecting abnormalities in glutamatergic transmission in the immediate post-stroke period...