G K Przybylski

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. pmc Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    J Transl Med 8:47. 2010
  2. doi request reprint Molecular characterization of a novel chromosomal translocation t(12;14)(q23;q11.2) in T-lymphoblastic lymphoma between the T-cell receptor delta-deleting elements (TRDREC and TRAJ61) and the hypothetical gene C12orf42
    Grzegorz K Przybylski
    Klinik für Innere Medizin C, Universitat Greifswald, Germany
    Eur J Haematol 85:452-6. 2010
  3. ncbi request reprint No recovery of T-cell receptor excision circles (TRECs) after non-myeloablative allogeneic hematopoietic stem cell transplantation is correlated with the onset of GvHD
    Grzegorz K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, Poznan, Poland
    J Appl Genet 48:397-404. 2007
  4. ncbi request reprint The effect of a novel recombination between the homeobox gene NKX2-5 and the TRD locus in T-cell acute lymphoblastic leukemia on activation of the NKX2-5 gene
    Grzegorz K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    Haematologica 91:317-21. 2006
  5. ncbi request reprint Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL
    G K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    Leukemia 19:201-8. 2005
  6. pmc Identification of a new cluster of T-cell receptor delta recombining elements
    Grzegorz K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    Immunology 108:16-23. 2003
  7. ncbi request reprint Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL
    Willem A Dik
    Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands
    Blood 110:388-92. 2007
  8. ncbi request reprint Novel competitive PCR methods for quantitation of T-cell receptor delta (TCRD) gene rearrangements
    Michał M Masternak
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    J Appl Genet 43:235-44. 2002
  9. ncbi request reprint TRAV and TRBV repertoire, clonality and the proliferative history of umbilical cord blood T-cells
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Transpl Immunol 18:151-8. 2007
  10. ncbi request reprint Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history
    Isabel Marcolino
    Institute for Medical Microbiology and Hygiene, University of Freiburg, Freiburg, Germany
    Eur J Immunol 34:2672-80. 2004

Collaborators

  • Piotr Grabarczyk
  • Anton W Langerak
  • J Huehn
  • A Bartke
  • Jian Wang
  • Yangqiu Li
  • MICHAL MATEUSZ MASTERNAK
  • Christian A Schmidt
  • Willem A Dik
  • Karin Fischer
  • Isabel Marcolino
  • Sonja Kimmig
  • Elizabeth A Macintyre
  • Vahid Asnafi
  • Jean Marc Navarro
  • Bertrand Nadel
  • Brenda Verhaaf
  • Jacques J M van Dongen
  • Jana Heymann
  • Simon Voelkl
  • Andreas Mackensen
  • Reinhard Andreesen
  • Leoni Kunz-Schughart
  • Monika Laumer
  • Krishna Mondal
  • Marie Koschella
  • Hanspeter Pircher
  • Michael Schlesier
  • David Voehringer
  • Katja Laurisch
  • Beate Möwes
  • Andreas Thiel
  • Andreas Radbruch

Detail Information

Publications15

  1. pmc Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    J Transl Med 8:47. 2010
    ..Based on our previous finding, to further characterize the immune status, T cell proliferative history was analyzed in CD4+ and CD8+ T cells from chronic myeloid leukemia (CML) patients...
  2. doi request reprint Molecular characterization of a novel chromosomal translocation t(12;14)(q23;q11.2) in T-lymphoblastic lymphoma between the T-cell receptor delta-deleting elements (TRDREC and TRAJ61) and the hypothetical gene C12orf42
    Grzegorz K Przybylski
    Klinik für Innere Medizin C, Universitat Greifswald, Germany
    Eur J Haematol 85:452-6. 2010
    ....
  3. ncbi request reprint No recovery of T-cell receptor excision circles (TRECs) after non-myeloablative allogeneic hematopoietic stem cell transplantation is correlated with the onset of GvHD
    Grzegorz K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, Poznan, Poland
    J Appl Genet 48:397-404. 2007
    ..Our results indicate that no recovery of TRECs after NM-HSCT (which most likely reflect the expansion of host-reactive co-transplanted mature T-cells) correlates with the onset of GvHD...
  4. ncbi request reprint The effect of a novel recombination between the homeobox gene NKX2-5 and the TRD locus in T-cell acute lymphoblastic leukemia on activation of the NKX2-5 gene
    Grzegorz K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    Haematologica 91:317-21. 2006
    ..Here, we describe for the first time a fusion between NKX2-5 and the T-cell receptor delta locus (TRD) resulting in NKX2-5 activation in a case of T-cell acute lymphoblastic leukemia (T-ALL)...
  5. ncbi request reprint Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL
    G K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    Leukemia 19:201-8. 2005
    ..As BCL11B appears to play a key role in T-cell differentiation, BCL11B disruption and disturbed expression may contribute to the development of T-cell malignancies in man...
  6. pmc Identification of a new cluster of T-cell receptor delta recombining elements
    Grzegorz K Przybylski
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    Immunology 108:16-23. 2003
    ..We hypothesize, that in a similar manner to the classical deltaRec rearrangements, the deltaRec2 rearrangements might also contribute to T-cell differentiation towards the TCR-alphabeta lineage...
  7. ncbi request reprint Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL
    Willem A Dik
    Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands
    Blood 110:388-92. 2007
    ....
  8. ncbi request reprint Novel competitive PCR methods for quantitation of T-cell receptor delta (TCRD) gene rearrangements
    Michał M Masternak
    Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
    J Appl Genet 43:235-44. 2002
    ..We showed that the rgc-PCR and cpc-PCR are reliable and give reproducible results. The methods do not require any expensive equipment or reagents, and can be used to determine the frequency of gene rearrangements...
  9. ncbi request reprint TRAV and TRBV repertoire, clonality and the proliferative history of umbilical cord blood T-cells
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Transpl Immunol 18:151-8. 2007
    ..The incomplete repertoire and naivety of CB T-cells might be the reason that CB hematopoietic stem cells transplant recipients are less likely to develop graft vs host disease...
  10. ncbi request reprint Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history
    Isabel Marcolino
    Institute for Medical Microbiology and Hygiene, University of Freiburg, Freiburg, Germany
    Eur J Immunol 34:2672-80. 2004
    ..Thus, analysis of KLRG1 expression in cord blood revealed an unexpected heterogeneity of human T cells in newborns...
  11. pmc Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells
    Jochen Huehn
    Experimentelle Rheumatologie, Medizinische Klinik, Charite, Humboldt Universitaet, Schumannstr 21 22, 10117 Berlin, Germany
    J Exp Med 199:303-13. 2004
    ..Accordingly, alphaE -expressing cells were found to be the most potent suppressors of inflammatory processes in disease models such as antigen-induced arthritis...
  12. ncbi request reprint Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice
    Michal M Masternak
    Department of Internal Medicine, Geriatrics Research, Southern Illnois University School of Medicine, Springfield, 62794 9628, USA
    J Gerontol A Biol Sci Med Sci 60:1238-45. 2005
    ..This suggested metabolic change clearly does not affect whole-body insulin action. These findings suggest that whole-animal insulin sensitivity is not regulated through skeletal muscle insulin action...
  13. ncbi request reprint Divergent effects of caloric restriction on gene expression in normal and long-lived mice
    Michal M Masternak
    Department of Internal Medicine, Southern Illinois University, School of Medicine, Springfield 62794 9628, USA
    J Gerontol A Biol Sci Med Sci 59:784-8. 2004
    ..Moreover, effects of dwarfism on the expression of the examined genes differed from the effects of CR, thus adding to the evidence that these long-lived mutants are not CR mimetics...
  14. ncbi request reprint Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells
    Karin Fischer
    Department of Hematology and Oncology, University of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    Blood 105:2828-35. 2005
    ..DN Treg cells may serve to limit clonal expansion of allo-Ag-specific T cells after transplantation...
  15. pmc Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
    Sonja Kimmig
    Department of Clinical Immunology, Deutsches Rheuma ForschungsZentrum Berlin, Schumannstrasse 21 22, 10117 Berlin, Germany
    J Exp Med 195:789-94. 2002
    ..We describe here the identification of peripherally expanded naive Th cells in human adult blood characterized by the loss of CD31 expression and a highly reduced TREC content...