Ryszard Pluta

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. ncbi Glial expression of the beta-amyloid peptide in cardiac arrest
    Ryszard Pluta
    Department of Neuropathology, Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    J Neurol Sci 203:277-80. 2002
  2. pmc Neuronal Autophagy: Self-eating or Self-cannibalism in Alzheimer's Disease
    Marzena Ułamek-Kozioł
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106, Warsaw, Poland
    Neurochem Res 38:1769-73. 2013
  3. ncbi Ischemia signalling to Alzheimer-related genes
    Ryszard Pluta
    Prof Ryszard Pluta, MD, PhD, Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland phone 48 22 608 65 40 or 608 64 69, fax 48 22 668 55 32, E mail
    Folia Neuropathol 50:322-9. 2012
  4. pmc Brain ischemia activates β- and γ-secretase cleavage of amyloid precursor protein: significance in sporadic Alzheimer's disease
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, 02 106, Warsaw, Pawinskiego 5 Str, Poland
    Mol Neurobiol 47:425-34. 2013
  5. ncbi Alzheimer's factors in postischemic dementia
    R Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Rom J Morphol Embryol 53:461-6. 2012
  6. ncbi Postischemic dementia with Alzheimer phenotype: selectively vulnerable versus resistant areas of the brain and neurodegeneration versus β-amyloid peptide
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Folia Neuropathol 50:101-9. 2012
  7. ncbi Consideration of the ischaemic basis and treatment of Alzheimer's disease
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    Folia Neuropathol 48:11-26. 2010
  8. doi Alzheimer's mechanisms in ischemic brain degeneration
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, Warsaw, Poland
    Anat Rec (Hoboken) 292:1863-81. 2009
  9. doi Factors in creepy delayed neuronal death in hippocampus following brain ischemia-reperfusion injury with long-term survival
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Acta Neurochir Suppl 106:37-41. 2010
  10. ncbi Ischemic blood-brain barrier and amyloid in white matter as etiological factors in leukoaraiosis
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    Acta Neurochir Suppl 102:353-6. 2008

Collaborators

Detail Information

Publications22

  1. ncbi Glial expression of the beta-amyloid peptide in cardiac arrest
    Ryszard Pluta
    Department of Neuropathology, Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    J Neurol Sci 203:277-80. 2002
    ..A glial appearance of beta-amyloid peptide direct staining occurred at a time when extensive neuronal loss was evident...
  2. pmc Neuronal Autophagy: Self-eating or Self-cannibalism in Alzheimer's Disease
    Marzena Ułamek-Kozioł
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106, Warsaw, Poland
    Neurochem Res 38:1769-73. 2013
    ..In this review we present the recent evidence linking autophagy to Alzheimer's disease and the role of autophagic regulation in the development of full-blown Alzheimer's disease. ..
  3. ncbi Ischemia signalling to Alzheimer-related genes
    Ryszard Pluta
    Prof Ryszard Pluta, MD, PhD, Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland phone 48 22 608 65 40 or 608 64 69, fax 48 22 668 55 32, E mail
    Folia Neuropathol 50:322-9. 2012
    ..Additionally, knowledge gained from the reviewed studies should facilitate the elaboration of effective treatment and/or prevention of sporadic Alzheimer's disease...
  4. pmc Brain ischemia activates β- and γ-secretase cleavage of amyloid precursor protein: significance in sporadic Alzheimer's disease
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, 02 106, Warsaw, Pawinskiego 5 Str, Poland
    Mol Neurobiol 47:425-34. 2013
    ..In our review, we demonstrated the role of brain ischemia as a molecular link between the β- and the γ-secretase activities and provided a molecular explanation of the possible neuropathogenesis of sporadic Alzheimer's disease...
  5. ncbi Alzheimer's factors in postischemic dementia
    R Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Rom J Morphol Embryol 53:461-6. 2012
    ....
  6. ncbi Postischemic dementia with Alzheimer phenotype: selectively vulnerable versus resistant areas of the brain and neurodegeneration versus β-amyloid peptide
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Folia Neuropathol 50:101-9. 2012
    ....
  7. ncbi Consideration of the ischaemic basis and treatment of Alzheimer's disease
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    Folia Neuropathol 48:11-26. 2010
    ..This review summarizes the latest advances in this area focusing on investigations based on in vivo animal studies...
  8. doi Alzheimer's mechanisms in ischemic brain degeneration
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, Warsaw, Poland
    Anat Rec (Hoboken) 292:1863-81. 2009
    ..New therapeutic alternatives targeting these proteins and repairing related neuronal changes are under development for the treatment of ischemic brain consequences including memory loss prevention...
  9. doi Factors in creepy delayed neuronal death in hippocampus following brain ischemia-reperfusion injury with long-term survival
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Acta Neurochir Suppl 106:37-41. 2010
    ..These findings also suggest that the blood-brain barrier vessels along the hippocampal fissure especially in the medial part of the hippocampus are more vulnerable to ischemic episodes than those in other hippocampal areas...
  10. ncbi Ischemic blood-brain barrier and amyloid in white matter as etiological factors in leukoaraiosis
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    Acta Neurochir Suppl 102:353-6. 2008
    ..It is not clear whether the blood-brain barrier in ischemic periventricular white matter is altered in aged animals...
  11. ncbi Role of ischemic blood-brain barrier on amyloid plaques development in Alzheimer's disease brain
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, 02 106 Warsaw, Pawinskiego 5 Str, Poland
    Curr Neurovasc Res 4:121-9. 2007
    ..This review presented chronic micro-blood-brain barrier openings in ischemic gray and white matter lesions that probably would act as seeds of future Alzheimer's amyloid plaques...
  12. ncbi Is the ischemic blood-brain barrier insufficiency responsible for full-blown Alzheimer's disease?
    Ryszard Pluta
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Neurol Res 28:665-71. 2006
    ..Finally, our review proposes the ischemic BBB-dependent mechanism(s) that probably are responsible for full-blown Alzheimer's disease...
  13. ncbi Pathological opening of the blood-brain barrier to horseradish peroxidase and amyloid precursor protein following ischemia-reperfusion brain injury
    Ryszard Pluta
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Warsaw, Poland
    Chemotherapy 51:223-6. 2005
    ..This pathology appears to have a similar distribution as in Alzheimer's disease, hippocampal and cortical changes being most severe...
  14. ncbi Astroglial expression of the beta-amyloid in ischemia-reperfusion brain injury
    Ryszard Pluta
    Department of Neuropathology, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warsaw, Poland
    Ann N Y Acad Sci 977:102-8. 2002
    ..The localization of the C-terminal of amyloid precursor protein within ischemic astroglial cells underscores the likely importance of the C-terminal of amyloid precursor protein in the pathogenesis of ischemia as in Alzheimer's disease...
  15. ncbi From brain ischemia-reperfusion injury to possible sporadic Alzheimer's disease
    Ryszard Pluta
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, 02 106 Warsaw, Pawinskiego 5 Str, Poland
    Curr Neurovasc Res 1:441-53. 2004
    ..We will summarize the results with a special focus on Alzheimer lesions in experimental brain ischemia...
  16. ncbi Alzheimer lesions after ischemia-reperfusion brain injury
    Ryszard Pluta
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    Folia Neuropathol 42:181-6. 2004
    ..Taken all together, evidence presented in this review suggests a scheme for Alzheimer's pathogenesis with ischemia playing a crucial role in influencing and linking beta-amyloid deposition to neuronal damage and clinical disease...
  17. ncbi Cognitive impairment with vascular impairment and degeneration
    Ryszard Pluta
    Laboratory of Ischemic and Neurodegenerative Brain Research, Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Curr Neurovasc Res 8:342-50. 2011
    ....
  18. doi Transient brain ischemia due to cardiac arrest causes irreversible long-lasting cognitive injury
    Anna Kiryk
    Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02 093 Warsaw, 3 Pasteur Str, Poland
    Behav Brain Res 219:1-7. 2011
    ..In old animals, a decline of motor and cognitive functions was found not only in ischemic but also in sham/control ones. This study describes consequences of global brain ischemia in aging animals...
  19. ncbi One year follow up in ischemic brain injury and the role of Alzheimer factors
    M Jabłoński
    Department of Ortopedics and Rehabilitation, Lublin Medical University, Lublin, Poland
    Physiol Res 60:S113-9. 2011
    ..Chronic ischemic BBB insufficiency with accumulation of toxic components of APP in the brain tissue perivascular space, may gradually over a lifetime, progress to brain atrophy and to full blown Alzheimer-type pathology...
  20. ncbi Amyloid beta(1-42) and its beta(25-35) fragment induce activation and membrane translocation of cytosolic phospholipase A2 in bovine retina capillary pericytes
    Carmelina Daniela Anfuso
    Department of Biochemistry, Faculty of Medicine, University of Catania, Viale A Doria 6, 95125 Catania, Italy
    Biochim Biophys Acta 1686:125-38. 2004
    ..The data confirm the hypothesis that pericytes could be a target of potential vascular damage and reactivity during processes involving amyloid accumulation...
  21. ncbi Complications of a trophic xenotransplant approach in parkinsonian monkeys
    Pierre J Blanchet
    Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Prog Neuropsychopharmacol Biol Psychiatry 27:607-12. 2003
    ..Membrane biophysics, the cell type used, and the extended period of time the devices remained in situ may have contributed to the negative outcome and should be addressed in future investigations using this approach...
  22. ncbi [Lactoferrin in the central nervous system]
    Mariusz Sacharczuk
    Zakład Cytogenetyki Molekularnej, Instytut Genetyki i Hodowli Zwierzat, Polska Akademia Nauk, ul Postepu 1, 05 552 Jastrzebiec
    Neurol Neurochir Pol 39:482-9. 2005
    ..LF suppresses distress perception via opioid mediated mechanism and prevents a decrease of the immune system activity caused by psychosocial stress. Furthermore, LF possibly modulates behavior in man and in animals...