Aleksandra Maruszak

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. ncbi Mitochondrial DNA in pathogenesis of Alzheimer's and Parkinson's diseases
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    Acta Neurobiol Exp (Wars) 66:153-76. 2006
  2. ncbi Sigma receptor type 1 gene variation in a group of Polish patients with Alzheimer's disease and mild cognitive impairment
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Dement Geriatr Cogn Disord 23:432-8. 2007
  3. doi Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Polish Academy of Sciences Medical Research Center, 5 Pawinskiego Street, 02 106 Warsaw, Poland
    Neurobiol Aging 30:1749-55. 2009
  4. pmc PIN1 gene variants in Alzheimer's disease
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    BMC Med Genet 10:115. 2009
  5. doi Mitochondrial dysfunction and Alzheimer's disease
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warszawa, Poland
    Prog Neuropsychopharmacol Biol Psychiatry 35:320-30. 2011
  6. doi Mitochondrial transcription factor A variants and the risk of Parkinson's disease
    Katarzyna Gaweda-Walerych
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warsaw, Poland
    Neurosci Lett 469:24-9. 2010
  7. doi TOMM40 and APOE common genetic variants are not Parkinson's disease risk factors
    Beata Peplonska
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    Neurobiol Aging 34:2078.e1-2. 2013
  8. doi The impact of mitochondrial and nuclear DNA variants on late-onset Alzheimer's disease risk
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    J Alzheimers Dis 27:197-210. 2011
  9. doi Mitochondrial DNA haplogroups and subhaplogroups are associated with Parkinson's disease risk in a Polish PD cohort
    Katarzyna Gaweda-Walerych
    Department of Neurodegenerative Disorders, Medical Research Center Polish Academy of Sciences, Pawinskiego 5, 02 106, Warsaw, Poland
    J Neural Transm 115:1521-6. 2008
  10. doi TOMM40 rs10524523 polymorphism's role in late-onset Alzheimer's disease and in longevity
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    J Alzheimers Dis 28:309-22. 2012

Collaborators

Detail Information

Publications14

  1. ncbi Mitochondrial DNA in pathogenesis of Alzheimer's and Parkinson's diseases
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    Acta Neurobiol Exp (Wars) 66:153-76. 2006
    ..This paper reviews the current knowledge on the inherited and somatic mtDNA variations in both conditions...
  2. ncbi Sigma receptor type 1 gene variation in a group of Polish patients with Alzheimer's disease and mild cognitive impairment
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Dement Geriatr Cogn Disord 23:432-8. 2007
    ..Multivariate logistic regression analysis showed no interaction between the APOE4 and SIGMAR1 polymorphisms. Further studies using data from different populations are required to elucidate the effect of SIGMAR1 polymorphisms on AD...
  3. doi Mitochondrial haplogroup H and Alzheimer's disease--is there a connection?
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Polish Academy of Sciences Medical Research Center, 5 Pawinskiego Street, 02 106 Warsaw, Poland
    Neurobiol Aging 30:1749-55. 2009
    ..We conclude that further analysis of subtypes of haplogroup H would be necessary to decipher the relation of HV cluster with AD...
  4. pmc PIN1 gene variants in Alzheimer's disease
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    BMC Med Genet 10:115. 2009
    ..There are confounding results concerning PIN1 activity in AD brains. Also PIN1 genetic variation was inconsistently associated with AD risk...
  5. doi Mitochondrial dysfunction and Alzheimer's disease
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5 Str, 02 106 Warszawa, Poland
    Prog Neuropsychopharmacol Biol Psychiatry 35:320-30. 2011
    ..We summarize the current data regarding the proteins involved in mitochondrial function and pathology observed in AD, and discuss the role of somatic mutations and mitochondrial haplogroups in AD development...
  6. doi Mitochondrial transcription factor A variants and the risk of Parkinson's disease
    Katarzyna Gaweda-Walerych
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warsaw, Poland
    Neurosci Lett 469:24-9. 2010
    ..523, p=0.0334). Conversely, four of five haplotypes containing allele G had higher frequencies in PD group, with no statistical significance...
  7. doi TOMM40 and APOE common genetic variants are not Parkinson's disease risk factors
    Beata Peplonska
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    Neurobiol Aging 34:2078.e1-2. 2013
    ..No significant association was observed at the single allele, genotype, or haplotype levels. Our data suggest that the polymorphism is not a risk factor for Parkinson's disease in the Polish population...
  8. doi The impact of mitochondrial and nuclear DNA variants on late-onset Alzheimer's disease risk
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    J Alzheimers Dis 27:197-210. 2011
    ..009) and between TFAM rs1937 and APOE4 status (p < 0.001) were detected, influencing LOAD risk. No interaction pointing to a dual mitochondrial-nuclear genome variation effect on LOAD occurrence was identified...
  9. doi Mitochondrial DNA haplogroups and subhaplogroups are associated with Parkinson's disease risk in a Polish PD cohort
    Katarzyna Gaweda-Walerych
    Department of Neurodegenerative Disorders, Medical Research Center Polish Academy of Sciences, Pawinskiego 5, 02 106, Warsaw, Poland
    J Neural Transm 115:1521-6. 2008
    ..We propose that stratification into subhaplogroups or by gender could be necessary to reveal the involvement of specific mtDNA sublineages in PD pathogenesis...
  10. doi TOMM40 rs10524523 polymorphism's role in late-onset Alzheimer's disease and in longevity
    Aleksandra Maruszak
    Department of Neurodegenerative Disorders, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warszawa, Poland
    J Alzheimers Dis 28:309-22. 2012
    ..Nevertheless, TOMM40 L allele increases the risk when E4 is absent. Finally, L allele, as well as genotypes (S/L, V/L) and haplotypes (L-E3, L-E4) comprising L significantly reduce the likelihood of living up to 100 years...
  11. ncbi Association between plasma biomarkers, CDK5 polymorphism and the risk of Alzheimer's disease
    Grzegorz A Czapski
    Department of Cellular Signaling, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
    Acta Neurobiol Exp (Wars) 72:397-411. 2012
    ..In conclusion, our study demonstrated that alteration of cholesterol, LDL, HDL, homocysteine and B12 concentration may be an important factor in pathogenesis of AD...
  12. ncbi Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration
    Zygmunt Jamrozik
    Department of Neurology, Medical University of Warsaw, Warsaw, Poland
    Ann Clin Lab Sci 43:151-3. 2013
    ..In the group of 77 patients with MSA, 44 with PSP, and 6 with CBD, no pathogenic mutations were identified...
  13. ncbi Two novel presenilin 1 gene mutations connected with frontotemporal dementia-like clinical phenotype: genetic and bioinformatic assessment
    Cezary Zekanowski
    Department of Neurodegenerative Disorders, Medical Research Center, Polish Academy of Sciences, Pawinskiego 5, 02 106 Warszawa, Poland
    Exp Neurol 200:82-8. 2006
    ..We also propose that PSEN1 mutations should be considered in FTD patients with no MAPT mutations...
  14. ncbi Association study of cholesterol-related genes in Alzheimer's disease
    M Axel Wollmer
    Division of Psychiatry Research, University of Zurich, August Forel Str 1, 8008 Zurich, Switzerland
    Neurogenetics 8:179-88. 2007
    ..004). We conclude that genetic variants investigated in this study may be associated with a moderate modification of the risk for AD in some samples...