Małgorzata Frankowska

Summary

Affiliation: Polish Academy of Sciences
Country: Poland

Publications

  1. doi request reprint Cocaine exposure alters H2S tissue concentrations in peripheral mouse organs
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, Krakow, Poland Electronic address
    Pharmacol Rep 67:421-5. 2015
  2. doi request reprint The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, Smetna 12, Poland Electronic address
    Behav Brain Res 266:108-18. 2014
  3. doi request reprint Effects of cocaine self-administration and extinction on D2 -like and A2A receptor recognition and D2 -like/Gi protein coupling in rat striatum
    Malgorzata Frankowska
    Institute of Pharmacology Polish Academy of Sciences, Department of Pharmacology, Smetna 12, Krakow, Poland
    Addict Biol 18:455-66. 2013
  4. ncbi request reprint Effects of GABAB receptor ligands in animal tests of depression and anxiety
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 59:645-55. 2007
  5. ncbi request reprint Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats
    Małgorzata Filip
    Institute of Pharmacology, Polish Academy of Sciences, Smetna Street 12, 31 343, Krakow, Poland
    Psychopharmacology (Berl) 192:17-26. 2007
  6. ncbi request reprint Alterations in BDNF and trkB mRNAs following acute or sensitizing cocaine treatments and withdrawal
    Małgorzata Filip
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna, 31 343 Krakow, Poland
    Brain Res 1071:218-25. 2006
  7. doi request reprint Neuroadaptive changes in the rat brain GABA(B) receptors after withdrawal from cocaine self-administration
    Małgorzata Frankowska
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Eur J Pharmacol 599:58-64. 2008
  8. ncbi request reprint Effects of serotonin 5-HT1B receptor ligands on the cocaine- and food-maintained self-administration in rats
    Edmund Przegalinski
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, 12 Smetna, Poland
    Eur J Pharmacol 559:165-72. 2007
  9. ncbi request reprint Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, 12 Smetna, Poland
    Eur J Pharmacol 571:166-73. 2007
  10. ncbi request reprint Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Eur J Pharmacol 574:148-57. 2007

Detail Information

Publications27

  1. doi request reprint Cocaine exposure alters H2S tissue concentrations in peripheral mouse organs
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, Krakow, Poland Electronic address
    Pharmacol Rep 67:421-5. 2015
    ..Among several factors that change the concentration of H2S, oxidative stress and generation of reactive oxygen species, which accompany neurochemical actions of drugs of abuse, are of recent interest...
  2. doi request reprint The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, Smetna 12, Poland Electronic address
    Behav Brain Res 266:108-18. 2014
    ..The last finding demonstrates the potential clinical utility of NAC to reduce cocaine seeking enhanced by co-existing depression. ..
  3. doi request reprint Effects of cocaine self-administration and extinction on D2 -like and A2A receptor recognition and D2 -like/Gi protein coupling in rat striatum
    Malgorzata Frankowska
    Institute of Pharmacology Polish Academy of Sciences, Department of Pharmacology, Smetna 12, Krakow, Poland
    Addict Biol 18:455-66. 2013
    ....
  4. ncbi request reprint Effects of GABAB receptor ligands in animal tests of depression and anxiety
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 59:645-55. 2007
    ....
  5. ncbi request reprint Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats
    Małgorzata Filip
    Institute of Pharmacology, Polish Academy of Sciences, Smetna Street 12, 31 343, Krakow, Poland
    Psychopharmacology (Berl) 192:17-26. 2007
    ..Recent data indicate that gamma-aminobutyric acid (GABA) is a modulator of behavioral responses to cocaine...
  6. ncbi request reprint Alterations in BDNF and trkB mRNAs following acute or sensitizing cocaine treatments and withdrawal
    Małgorzata Filip
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna, 31 343 Krakow, Poland
    Brain Res 1071:218-25. 2006
    ....
  7. doi request reprint Neuroadaptive changes in the rat brain GABA(B) receptors after withdrawal from cocaine self-administration
    Małgorzata Frankowska
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Eur J Pharmacol 599:58-64. 2008
    ..Furthermore, withdrawal from cocaine self-administration evoked changes in the GABA(B) receptor binding in several rat brain areas that may indicate neurobiological adaptations...
  8. ncbi request reprint Effects of serotonin 5-HT1B receptor ligands on the cocaine- and food-maintained self-administration in rats
    Edmund Przegalinski
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, 12 Smetna, Poland
    Eur J Pharmacol 559:165-72. 2007
    ..Furthermore, we demonstrated that 5-HT1B receptor agonist-induced enhancement of cocaine reward was independent of an alteration in natural reinforcement...
  9. ncbi request reprint Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, 12 Smetna, Poland
    Eur J Pharmacol 571:166-73. 2007
    ....
  10. ncbi request reprint Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Eur J Pharmacol 574:148-57. 2007
    ..Moreover, a dissociation between effects of direct GABA(B) receptor agonists and a GABA(B) allosteric positive modulator on cocaine vs. food-maintained responding was demonstrated...
  11. ncbi request reprint Effects of GABAB receptor agonists on cocaine hyperlocomotor and sensitizing effects in rats
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 61:1042-9. 2009
    ....
  12. ncbi request reprint Various GABA-mimetic drugs differently affect cocaine-evoked hyperlocomotion and sensitization
    Małgorzata Filip
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna, Poland
    Eur J Pharmacol 541:163-70. 2006
    ..The finding that vigabatrin protected against the development and the expression of cocaine sensitization further supports its therapeutic potential in the treatment of cocaine dependence...
  13. doi request reprint Effects of imipramine or GABA(B) receptor ligands on the immobility, swimming and climbing in the forced swim test in rats following discontinuation of cocaine self-administration
    Małgorzata Frankowska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Eur J Pharmacol 627:142-9. 2010
    ....
  14. doi request reprint Changes in the level of calcyon mRNA in the brain of rats exposed to cocaine, self-administered or received passively
    Agata Faron-Górecka
    Institute of Pharmacology, Polish Academy of Sciences, 12 Smetna Street, Krakow, Poland
    Eur J Pharmacol 634:33-9. 2010
    ..Such a result together with the brain areas involved in these effects might suggest the role of calcyon similar to the CART peptides and special vulnerability of calcyon expression rather to acute than chronic stimuli...
  15. ncbi request reprint Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine
    Małgorzata Filip
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Brain Res 1077:67-80. 2006
    ..The results suggest an antagonistic role of A2ARs in D2R-mediated cocaine actions based at least in part on the existence of A2A/D2 heteromeric receptor complexes...
  16. ncbi request reprint Alterations in gamma-aminobutyric acid(B) receptor binding in the rat brain after reinstatement of cocaine-seeking behavior
    Małgorzata Frankowska
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Science, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 60:834-43. 2008
    ..Increases in GABA(B) receptor binding in limbic regions during cocaine-induced reinstatement likely reflect motivational states that were present during active drug self-administration...
  17. ncbi request reprint Effects of CP 154,526, a CRF1 receptor antagonist, on behavioral responses to cocaine in rats
    Edmund Przegalinski
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, 31 343 Krakow, Poland
    Neuropeptides 39:525-33. 2005
    ..These findings may suggest that CRF1 receptor antagonists should be considered as possible medications in the treatment of cocaine addiction...
  18. ncbi request reprint GABA(B) receptors in drug addiction
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 60:755-70. 2008
    ..It also reviews the current knowledge about the GABA(B) receptor ligands in clinical trials, with a focus on their effects on presentation of the drug-associated cues and withdrawal-induced drug craving...
  19. doi request reprint Cocaine self-administration in Wistar-Kyoto rats: a behavioral and biochemical analysis
    Joanna Jastrzębska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Smetna 12, Poland
    Behav Brain Res 293:62-73. 2015
    ..This finding suggests that WKY rats should not be used to investigate the co-occurrence of depression and cocaine addiction, as this rat strain does not show an enhanced risk of relapse. ..
  20. ncbi request reprint WIN 55,212-2-induced reduction of cocaine hyperlocomotion: possible inhibition of 5-HT(3) receptor function
    Edmund Przegalinski
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, Poland
    Eur J Pharmacol 517:68-73. 2005
    ..Moreover, together with the literature data they may suggest that this effect of WIN 55,212-2 involves inhibition of the 5-HT(3) receptor function...
  21. ncbi request reprint Preclinical studies on comorbidity between depression and psychostimulant addiction
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 65:1529-34. 2013
    ....
  22. doi request reprint Adenosine (A)(2A)receptor modulation of nicotine-induced locomotor sensitization. A pharmacological and transgenic approach
    Joanna Jastrzębska
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Neuropharmacology 81:318-26. 2014
    ..It is suggested that treatment with A(2A) receptor agonists can help counteract the abuse actions of nicotine...
  23. ncbi request reprint The serotonergic system and its role in cocaine addiction
    Małgorzata Filip
    Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
    Pharmacol Rep 57:685-700. 2005
    ..The present state of knowledge of 5-HT neurotransmission justifies the opinion that pharmacological manipulation in the 5-HT system may efficiently counteract the effects of cocaine withdrawal and prevent reinstatement of its abuse...
  24. doi request reprint GABAB receptors as a therapeutic strategy in substance use disorders: focus on positive allosteric modulators
    Małgorzata Filip
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, 31 343 Krakow, Smetna 12, Poland Electronic address
    Neuropharmacology 88:36-47. 2015
    ..In summary, a wealth of data now supports the benefits of GABAB receptor PAMs and clinical validation is now warranted...
  25. pmc Withdrawal from cocaine self-administration and yoked cocaine delivery dysregulates glutamatergic mGlu5 and NMDA receptors in the rat brain
    Lucyna Pomierny-Chamiolo
    Department of Toxicology, Department of Biochemical Toxicology, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, 30 688, Krakow, Poland
    Neurotox Res 27:246-58. 2015
    ....
  26. doi request reprint The effect of active and passive intravenous cocaine administration on the extracellular signal-regulated kinase (ERK) activity in the rat brain
    Joanna Miszkiel
    Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland
    Pharmacol Rep 66:630-7. 2014
    ..Our findings suggest that cortical ERK is involved in cocaine seeking behavior in rats. They also indicate the time and regional adaptations in this enzyme activity after cocaine withdrawal. ..
  27. doi request reprint Mitoepigenetics and drug addiction
    Anna Sadakierska-Chudy
    Institute of Pharmacology Polish Academy of Sciences, Laboratory of Drug Addiction Pharmacology, Krakow, Poland Electronic address
    Pharmacol Ther 144:226-33. 2014
    ..This review summarizes recent findings on mitochondrial function, mtDNA copy number and epigenetics in drug addiction. ..