Research Topics

Genomes and Genes

Species

T Pawełczyk

Summary

Country: Poland

Publications

  1. request reprint
    Pawełczyk T, Matecki A. Expression, purification and kinetic properties of human recombinant phospholipase C delta 3. Acta Biochim Pol. 1997;44:221-9 pubmed
    ..The data presented indicate that the expression of PLC delta 3 in E. coli cells permits to obtain active enzyme. The catalytic and regulatory properties of PLC delta 3 are similar to those of PLC delta 1. ..
  2. request reprint
    Pawelczyk T, Matecki A. Localization of phospholipase C delta3 in the cell and regulation of its activity by phospholipids and calcium. Eur J Biochem. 1998;257:169-77 pubmed
    ..The regulatory properties of PLC delta3 described in this report suggest that PLC delta3 has a relatively low activity in cellular conditions that fully activate PLC delta1. ..
  3. request reprint
    Pawelczyk T, Matecki A. Phospholipase C-delta3 binds with high specificity to phosphatidylinositol 4,5-bisphosphate and phosphatidic acid in bilayer membranes. Eur J Biochem. 1999;262:291-8 pubmed
    ..We propose that binding of PLC-delta3 to PA may serve as a mechanism for dynamic membrane association and modulation of PLC-delta3 activity. ..

Detail Information

Publications3

  1. request reprint
    Pawełczyk T, Matecki A. Expression, purification and kinetic properties of human recombinant phospholipase C delta 3. Acta Biochim Pol. 1997;44:221-9 pubmed
    ..The data presented indicate that the expression of PLC delta 3 in E. coli cells permits to obtain active enzyme. The catalytic and regulatory properties of PLC delta 3 are similar to those of PLC delta 1. ..
  2. request reprint
    Pawelczyk T, Matecki A. Localization of phospholipase C delta3 in the cell and regulation of its activity by phospholipids and calcium. Eur J Biochem. 1998;257:169-77 pubmed
    ..The regulatory properties of PLC delta3 described in this report suggest that PLC delta3 has a relatively low activity in cellular conditions that fully activate PLC delta1. ..
  3. request reprint
    Pawelczyk T, Matecki A. Phospholipase C-delta3 binds with high specificity to phosphatidylinositol 4,5-bisphosphate and phosphatidic acid in bilayer membranes. Eur J Biochem. 1999;262:291-8 pubmed
    ..We propose that binding of PLC-delta3 to PA may serve as a mechanism for dynamic membrane association and modulation of PLC-delta3 activity. ..