Iwnoa Zak

Summary

Affiliation: Medical University of Silesia
Country: Poland

Publications

  1. ncbi request reprint Carrier-state of D allele in ACE gene insertion/deletion polymorphism is associated with coronary artery disease, in contrast to the C677-->T transition in the MTHFR gene
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow 18, 40 752 Katowice, Poland
    Acta Biochim Pol 50:527-34. 2003
  2. ncbi request reprint Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease
    Iwnoa Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Kardiol Pol 66:380-6; discussion 387. 2008
  3. ncbi request reprint Contemporaneous carrier-state of two or three "proatherosclerotic" variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Clin Chim Acta 362:110-8. 2005
  4. ncbi request reprint [Vascular NAD(P)H oxidases--role in the pathogenesis of atherosclerosis]
    Paweł Niemiec
    Department of Medical Biochemistry and Genetics, Medical University of Silesia, 18 Medykow St, 40 752 Katowice, Poland
    Postepy Biochem 51:1-11. 2005
  5. doi request reprint The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Eur J Epidemiol 23:349-54. 2008
  6. doi request reprint Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
    Beata Sarecka
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Clin Biochem 41:467-73. 2008
  7. doi request reprint The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Clin Chem Lab Med 46:446-52. 2008
  8. doi request reprint Modification of the coronary artery disease risk associated with the presence of traditional risk factors by insertion/deletion polymorphism of the ACE gene
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, 40 752 Katowice, Poland
    Genet Test 11:353-9. 2007
  9. ncbi request reprint Protective effect of R allele of PON1 gene on the coronary artery disease in the presence of specific genetic background
    Anna Balcerzyk
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Dis Markers 24:81-8. 2008
  10. ncbi request reprint [Apolipoprotein E--the role of polymorphism in pathogenesis of many diseases]
    Anna Balcerzyk
    Katedra i Zakład Biochemii i Genetyki Medycznej, Slaska Akademia Medyczna, ul Medykow 18, 40 752 Katowice
    Postepy Biochem 50:344-52. 2004

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Carrier-state of D allele in ACE gene insertion/deletion polymorphism is associated with coronary artery disease, in contrast to the C677-->T transition in the MTHFR gene
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow 18, 40 752 Katowice, Poland
    Acta Biochim Pol 50:527-34. 2003
    ..Our data indicate that in Silesian CAD patients the disease is strongly associated with carrier-state of the ACE D allele, but not with the C677-->T transition in the MTHFR gene...
  2. ncbi request reprint Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease
    Iwnoa Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Kardiol Pol 66:380-6; discussion 387. 2008
    ..The 46A>G and 79C>G polymorphisms of the beta2-adrenergic receptor gene (ADRB2) have been associated with altered response to sympathetic stimulation...
  3. ncbi request reprint Contemporaneous carrier-state of two or three "proatherosclerotic" variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Clin Chim Acta 362:110-8. 2005
    ....
  4. ncbi request reprint [Vascular NAD(P)H oxidases--role in the pathogenesis of atherosclerosis]
    Paweł Niemiec
    Department of Medical Biochemistry and Genetics, Medical University of Silesia, 18 Medykow St, 40 752 Katowice, Poland
    Postepy Biochem 51:1-11. 2005
    ..Specific inhibitors of NAD(P)H oxidases may be useful experimental tools for atherosclerosis research and may have potential therapeutic significance in the future...
  5. doi request reprint The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Eur J Epidemiol 23:349-54. 2008
    ..Recent evidence show that many traditional risk factors of coronary artery disease (CAD) influence synthesis of AGT. This report focuses on the interactions between M235T polymorphism of AGT gene and traditional risk factors of CAD...
  6. doi request reprint Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
    Beata Sarecka
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Clin Biochem 41:467-73. 2008
    ..To assess the relationship between IL-6 and PAI-1 polymorphisms and coronary artery disease (CAD) and to observe the interactions between these polymorphic variants and smoking in the CAD risk...
  7. doi request reprint The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Clin Chem Lab Med 46:446-52. 2008
    ....
  8. doi request reprint Modification of the coronary artery disease risk associated with the presence of traditional risk factors by insertion/deletion polymorphism of the ACE gene
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, 40 752 Katowice, Poland
    Genet Test 11:353-9. 2007
    ..The statistical significance was also confirmed by a multiplicative model of synergy. The DD genotype/D allele of the ACE gene increases the risk of CAD associated with the presence of traditional risk factors...
  9. ncbi request reprint Protective effect of R allele of PON1 gene on the coronary artery disease in the presence of specific genetic background
    Anna Balcerzyk
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Dis Markers 24:81-8. 2008
    ..Participation of single polymorphic variants is relatively small, however its significance may increase in the presence of specific genetic or environmental background...
  10. ncbi request reprint [Apolipoprotein E--the role of polymorphism in pathogenesis of many diseases]
    Anna Balcerzyk
    Katedra i Zakład Biochemii i Genetyki Medycznej, Slaska Akademia Medyczna, ul Medykow 18, 40 752 Katowice
    Postepy Biochem 50:344-52. 2004
  11. ncbi request reprint The 242T variant of the CYBA gene polymorphism increases the risk of coronary artery disease associated with cigarette smoking and hypercholesterolemia
    Pawel Niemiec
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Coron Artery Dis 18:339-46. 2007
    ..This report focuses on the interactions between C242T CYBA polymorphism and traditional risk factors of coronary artery disease (CAD), such as cigarette smoking and hypercholesterolemia...
  12. ncbi request reprint Synergistic effect between polymorphisms of PPARA and ABCA1 genes on the premature coronary artery disease
    Anna Balcerzyk
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Acta Cardiol 62:233-8. 2007
    ..The aim of the present study was to evaluate a possible interaction between R219K polymorphism of ABCA1 gene and G > C polymorphism in intron 7 of PPARA gene in determining the risk of the CAD...
  13. ncbi request reprint Synergistic effects between Q192R polymorphism of paraoxonase 1 gene and some conventional risk factors in premature coronary artery disease
    Anna Balcerzyk
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Arch Med Res 38:545-50. 2007
    ....
  14. ncbi request reprint Synergistic effects of apolipoprotein E gene epsilon polymorphism and some conventional risk factors on premature ischaemic heart disease development
    Anna Balcerzyk
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Kardiol Pol 65:1058-65; discussion 1066-7. 2007
    ..However, it seems that its significance may increase in the presence of a specific genetic or environmental background...