Research Topics
| C WojcikSummaryAffiliation: Medical University of Warsaw Country: Poland Publications
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Detail Information
Publications
Proteasome activator (PA28) subunits, alpha, beta and gamma (Ki antigen) in NT2 neuronal precursor cells and HeLa S3 cellsC Wojcik
Department of Pharmacology, Mount Sinai School of Medicine, New York, NY, USA
Eur J Cell Biol 77:151-60. 1998..PA28gamma complexed with the proteasome may serve a function other than or in addition to activation and may also have a proteasome-independent function...
Changes in proteasome expression and activity during differentiation of neuronal precursor NTera 2 clone D1 cellsC Wojcik
Department of Pharmacology, Mount Sinai School of Medicine, New York, NY, USA
Neurochem Int 34:131-6. 1999..Changes in proteasome activity and composition may contribute to the processes leading to differentiation of human neurons in vitro and to the properties of fully differentiated neurons...
Proteasome activator subunit PA28 alpha and related Ki antigen (PA28 gamma) are absent from the nuclear fraction purified by sucrose gradient centrifugationC Wojcik
Department of Histology and Embryology, Warsaw Medical Academy, Poland
Int J Biochem Cell Biol 31:273-6. 1999..This indicates, that only a small fraction of the PA28 activator is present in the nuclei as detected by immunofluorescence or/and it is easily removed during nuclear purification...
Proteasomes in human spermatozoaC Wojcik
Department of Histology and Embryology, Biostructure Centre, Warsaw Medical Academy, ul Chalubinskiego 5, 02 004 Warsaw, Poland
Int J Androl 23:169-77. 2000....
Lovastatin and simvastatin are modulators of the proteasomeC Wojcik
Department of Histology and Embryology, Biostructure Center, Warsaw Medical Academy, ul Chalubinskiego 5, 02 004 Warsaw, Poland
Int J Biochem Cell Biol 32:957-65. 2000....
Proteasomes in apoptosis: villains or guardians?C Wojcik
Department of Histology and Embryology, Institute of Biostructure, Medical University of Warsaw, Warszawa, Poland
Cell Mol Life Sci 56:908-17. 1999....
Regulation of apoptosis by the ubiquitin and proteasome pathwayCezary Wojcik
Department of Histology and Embryology, Center of Biostructure Research, Medical University of Warsaw, Warsaw, Poland
J Cell Mol Med 6:25-48. 2002....
Ubiquitin--more than just a signal for protein degradationC Wojcik
Medical University of Warsaw, Poland
Trends Cell Biol 11:397-9. 2001
Synergistic antitumor effects of a selective proteasome inhibitor and TNF in miceJ Golab
Department of Immunology, Medical University of Warsaw, Poland
Anticancer Res 20:1717-21. 2000..Similarly, the influence of these drugs on tumor induced angiogenesis does not seem to explain the observed antitumor effects. Further studies are necessary to explain the striking antitumor effects of the PSI and TNF combination...
Effects of the combination of a proteasome inhibitor (PSI) and an inhibitor of ubiquitin-ligases (Leu-Ala) on the ultrastructure of human leukemic U937 cellsL P Biały
Department of Histology and Embryology, Center of Biostructure Research, Medical Academy, Warsaw, Poland
Folia Histochem Cytobiol 40:135-6. 2002....
Augmented pro-apoptotic effects of TRAIL and proteasome inhibitor in human promonocytic leukemic U937 cellsI Młynarczuk
Department of Immunology, Medical University of Warsaw, 5 Chałubinskiego Str, PL 02 004 Warsaw, Poland
Anticancer Res 21:1237-40. 2001..TRAIL/PSI did not affect the level of mRNA expression for TRAIL receptors (DR4, DR5, DcR1) and other apoptosis signal transduction molecules (TRADD, caspase-8)...
Localization of a proteasomal antigen in human spermatozoa: immunohistochemical electron microscopic studyL P Biały
Department of Histology and Embryology, Medical Academy, Warsaw, Poland
Folia Histochem Cytobiol 39:129-30. 2001..The nuclear vacuoles with looser chromatin were usually strongly labeled. The nuclei of cells representing different stages of spermatogenesis, that were present in semen samples, were also labeled...
Effects of proteasome inhibitor PSI on neoplastic and non-transformed cell linesE Pleban
Department of Histology and Embryology, Medical Academy, Warsaw, Poland
Folia Histochem Cytobiol 39:133-4. 2001..Non-transformed cell lines showed no sensitivity to PSI, as there was no difference in cell viability in comparison with the control group even after 72 h incubation...
Proteasome localization and ultrastructure of spermatozoa from patients with varicocele--immunoelectron microscopic studyH Ziemba
Department of Histology and Embryology, Center of Biostructure Research, Medical Academy, Warsaw, Poland
Folia Histochem Cytobiol 40:169-70. 2002..The association of proteasomes with sperm chromatin and large residual bodies can be the sign of abnormality and disturbances in spermatogenesis associated with varicocele...
Increased local vascular endothelial growth factor expression associated with antitumor activity of proteasome inhibitorT Stokłosa
Department of Immunology, Center of Biostructure, Medical University of Warsaw, Warsaw, Poland
Apoptosis 9:193-204. 2004..We demonstrated that in C-26 colon adenocarcionoma higher VEGF production may render endothelial cells susceptible to the proapoptotic activity of PSI and is associated with inhibition of tumor growth...
Effects of an inhibitor of tripeptidyl peptidase II (Ala-Ala-Phe-chloromethylketone) and its combination with an inhibitor of the chymotrypsin-like activity of the proteasome (PSI) on apoptosis, cell cycle and proteasome activity in U937 cellsM Bury
Department of Histology and Embryology, Medical Academy, Warsaw, Poland
Folia Histochem Cytobiol 39:131-2. 2001..This suggests that TPP II is possibly less important for cell metabolism than it was previously believed and it is less probable that it can be able to fully compensate for the loss of the proteasome function...
