Jacek P Szaflik

Summary

Affiliation: Medical University of Warsaw
Country: Poland

Publications

  1. ncbi request reprint Therapeutic use of a lotrafilcon A silicone hydrogel soft contact lens as a bandage after LASEK surgery
    Jacek P Szaflik
    LASER Microsurgery Eye Center, ul Boya 4A, 00 621 Warsaw, Poland
    Eye Contact Lens 30:59-62. 2004
  2. ncbi request reprint [Posterior polymorphous dystrophy--changes in corneal morphology in confocal microscopy]
    Jacek P Szaflik
    Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Uniwersytetu Medycznego w Warszawie
    Klin Oczna 110:252-8. 2008
  3. doi request reprint Optical coherence tomography and in vivo confocal microscopy features of obstetric injury of the cornea
    Jacek P Szaflik
    Department of Ophthalmology, Center of Biostructure Research, Medical University of Warsaw, Warsaw, Poland
    Cornea 27:1070-3. 2008
  4. pmc Genetics of Meesmann corneal dystrophy: a novel mutation in the keratin 3 gene in an asymptomatic family suggests genotype-phenotype correlation
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Mol Vis 14:1713-8. 2008
  5. ncbi request reprint In vivo confocal microscopy of corneal grafts shortly after penetrating keratoplasty
    J P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Eur J Ophthalmol 17:891-6. 2007
  6. ncbi request reprint An association between vascular endothelial growth factor gene promoter polymorphisms and diabetic retinopathy
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Graefes Arch Clin Exp Ophthalmol 246:39-43. 2008
  7. ncbi request reprint Comparison of in vivo confocal microscopy of human cornea by white light scanning slit and laser scanning systems
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Cornea 26:438-45. 2007
  8. ncbi request reprint White light confocal microscopy of preserved human corneas from an eye bank
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw Eye Bank, Warsaw, Poland
    Cornea 26:265-9. 2007
  9. ncbi request reprint Confocal microscopy imaging of the cornea in patients with silicone oil in the anterior chamber after vitreoretinal surgery
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Graefes Arch Clin Exp Ophthalmol 245:210-4. 2007
  10. doi request reprint Association between sorbitol dehydrogenase gene polymorphisms and type 2 diabetic retinopathy
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Exp Eye Res 86:647-52. 2008

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Therapeutic use of a lotrafilcon A silicone hydrogel soft contact lens as a bandage after LASEK surgery
    Jacek P Szaflik
    LASER Microsurgery Eye Center, ul Boya 4A, 00 621 Warsaw, Poland
    Eye Contact Lens 30:59-62. 2004
    ..To evaluate a silicone hydrogel contact lens as a continuous wear bandage applied after laser-assisted sub-epithelial keratomileusis (LASEK)...
  2. ncbi request reprint [Posterior polymorphous dystrophy--changes in corneal morphology in confocal microscopy]
    Jacek P Szaflik
    Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Uniwersytetu Medycznego w Warszawie
    Klin Oczna 110:252-8. 2008
    ..To describe the in vivo conocal microscopic findings in posterior polymorphous dystrophy (PPD)...
  3. doi request reprint Optical coherence tomography and in vivo confocal microscopy features of obstetric injury of the cornea
    Jacek P Szaflik
    Department of Ophthalmology, Center of Biostructure Research, Medical University of Warsaw, Warsaw, Poland
    Cornea 27:1070-3. 2008
    ..There is a good correlation between the results of AS-OCT and IVCM...
  4. pmc Genetics of Meesmann corneal dystrophy: a novel mutation in the keratin 3 gene in an asymptomatic family suggests genotype-phenotype correlation
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Mol Vis 14:1713-8. 2008
    ..Seventeen mutations in KRT12 and two in KRT3 have been described so far. The purpose of this study was to investigate the genetic background of MCD in a Polish family...
  5. ncbi request reprint In vivo confocal microscopy of corneal grafts shortly after penetrating keratoplasty
    J P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Eur J Ophthalmol 17:891-6. 2007
    ..To describe the microstructural status of corneal grafts shortly after penetrating keratoplasty (PK) and to evaluate the efficacy and safety of confocal microscopy in examining corneal grafts at that time...
  6. ncbi request reprint An association between vascular endothelial growth factor gene promoter polymorphisms and diabetic retinopathy
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Graefes Arch Clin Exp Ophthalmol 246:39-43. 2008
    ..Reports have suggested that polymorphisms at positions -460 and -634 of the 5' untranslated region of the VEGF gene increase its basal promoter activity...
  7. ncbi request reprint Comparison of in vivo confocal microscopy of human cornea by white light scanning slit and laser scanning systems
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Cornea 26:438-45. 2007
    ..To compare in vivo corneal imaging by scanning slit white light and laser confocal microscopy systems...
  8. ncbi request reprint White light confocal microscopy of preserved human corneas from an eye bank
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw Eye Bank, Warsaw, Poland
    Cornea 26:265-9. 2007
    ..To verify the possibility of using a commercially available ophthalmologic white light confocal microscope for imaging optical sections of donated corneas preserved at 4 degrees C, especially for endothelial evaluation...
  9. ncbi request reprint Confocal microscopy imaging of the cornea in patients with silicone oil in the anterior chamber after vitreoretinal surgery
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Graefes Arch Clin Exp Ophthalmol 245:210-4. 2007
    ..Evaluation of corneal morphology by confocal microscopy after vitreoretinal surgery complicated by passage of silicone oil into the anterior chamber. Design Case series (case control study)...
  10. doi request reprint Association between sorbitol dehydrogenase gene polymorphisms and type 2 diabetic retinopathy
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Exp Eye Res 86:647-52. 2008
    ....
  11. doi request reprint Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1, and the 324Gln/His MUTYH gene polymorphisms with clinical parameters and the risk for development of primary open-angle glaucoma
    Jacek P Szaflik
    Department of Ophthalmology II, Medical Faculty, Medical University of Warsaw, Poland
    Mutat Res 753:12-22. 2013
    ..This hypothesis may suggest an association of base excision repair with the risk of primary open angle glaucoma development...
  12. ncbi request reprint Distribution of the C-460T polymorphism of the vascular endothelial growth factor gene in age-related macular degeneration
    Jacek P Szaflik
    Ophthalmology Department, Medical University of Warsaw, Warsaw, Poland
    Klin Oczna 111:125-7. 2009
    ..To assess the association between genotypes and alleles of the C-460T polymorphism of the vascular endothelial growth factor (VEGF) gene and the risk of wet form of age-related macular degeneration (AMD)...
  13. doi request reprint DNA damage and repair in age-related macular degeneration
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw and Samodzielny Publiczny Szpital Okulistyczny, Warsaw, Poland
    Mutat Res 669:169-76. 2009
    ..We postulate that the impaired efficacy of DNA repair may combine with enhanced sensitivity of RPE cells to blue and UV lights, contributing to the pathogenesis of AMD...
  14. ncbi request reprint Therapeutic use of a silicone hydrogel contact lens in selected clinical cases
    Anna M Ambroziak
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Eye Contact Lens 30:63-7. 2004
    ..To evaluate a silicone hydrogel contact lens as a continuous-wear bandage in selected clinical cases, a prospective, open, nonrandomized clinical study was conducted...
  15. ncbi request reprint Association between polymorphism of the NQO1, NOS3 and NFE2L2 genes and AMD
    Ewelina Synowiec
    Department of Ophthalmology, Medical University of Warsaw and Samodzielny Publiczny Kliniczny Szpital Okulistyczny, Sierakowskiego 13, 03 709 Warsaw, Poland
    Front Biosci (Landmark Ed) 18:80-90. 2013
    ..35). The results obtained in our study suggest a potential role of the rs1800566, rs1799983 and rs6726395 polymorphisms in the AMD pathogenesis...
  16. doi request reprint OCT and in vivo confocal microscopy of a pigmented corneal tumor-like lesion
    Jacek P Szaflik
    Department of Ophthalmology, Center of Biostructure Research, Medical University of Warsaw, Warsaw, Poland
    Ophthalmic Surg Lasers Imaging 40:586-8. 2009
    ..The authors conclude that anterior-segment optical coherence tomography and in vivo scanning slit confocal microscopy are useful in assessing the microstructure and penetration of pigmented corneal lesions...
  17. ncbi request reprint Clinical and microbiological efficacy of levofloxacin administered three times a day for the treatment of bacterial conjunctivitis
    J Szaflik
    Laser Eye Microsurgery Centre, Warsaw, Poland
    Eur J Ophthalmol 19:1-9. 2009
    ..5% eyedrops with the classic, more frequent dosing in patients with bacterial conjunctivitis...
  18. doi request reprint Gene polymorphisms of the MMP1, MMP9, MMP12, IL-1β and TIMP1 and the risk of primary open-angle glaucoma
    Lukasz Markiewicz
    Department of Clinical Chemistry and Biochemistry, Medical University of Lodz, Lodz, PolandDepartment of General and Colorectal Surgery, Medical University of Lodz, Lodz, PolandDepartment of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Acta Ophthalmol 91:e516-23. 2013
    ....
  19. doi request reprint Reactive oxygen species promote localized DNA damage in glaucoma-iris tissues of elderly patients vulnerable to diabetic injury
    Jacek P Szaflik
    Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
    Mutat Res 697:19-23. 2010
    ..4%; oxidized pyrimidines: 61.8% vs 23.3%; P<0.001). Our observations suggest that the generation of reactive oxygen species may promote localized DNA damage in glaucoma-iris tissues of elderly patients vulnerable to diabetic injury...
  20. doi request reprint Association between polymorphism of the DNA repair smug1 and ung genes and age-related macular degeneration
    Ewelina Synowiec
    Department of Molecular Genetics, University of Lodz, Pomorska, Lodz, Poland Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland and Samodzielny Publiczny Kliniczny Szpital Okulistyczny, Warsaw, Poland
    Retina 34:38-47. 2014
    ..31A>G (rs3087404) polymorphism of the SMUG1 gene and the risk of age-related macular degeneration (AMD), as well as modulation of this association by some environmental and lifestyle factors...
  21. doi request reprint A family with 3460G>A and 11778G>A mutations and haplogroup analysis of Polish Leber hereditary optic neuropathy patients
    Katarzyna Tonska
    Department of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5A, Warsaw, Poland
    Mitochondrion 8:383-8. 2008
    ..Double LHON mutations are extremely rare, and this particular combination has not been previously described in the literature...
  22. doi request reprint Influence of donor age, post-mortem time and cold storage on metabolic profile of human cornea
    Tomasz Kryczka
    Faculty of Medicine, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Acta Ophthalmol 91:83-7. 2013
    ..The aim of this study is to investigate the relationship between both factors and metabolite content of the cornea...
  23. ncbi request reprint [Levofloxacin (oftaquix) a fluoroquinolone of a new generation in prevention of the postoperative endophthalmitis following uncomplicated cataract surgery--the study of the European Society of Cataract and Refractive Surgeons (ESCRS)]
    Justyna Izdebska
    Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Akademii Medycznej w Warszawie
    Klin Oczna 107:344-7. 2005
    ..05% (less than 1 per 2 000 surgeries). The patients will be divided into four groups; different regimes of two antibiotics: cefuroxime injected intra-camerally and levofloxacine eye drops topically will be compared...
  24. ncbi request reprint [European multicenter randomized clinical study of antibiotic prophylaxis for internal eye infection after cataract surgery--study of the European Society for Cataract and Refractive Surgery (ESCRS). The beginnings in Poland]
    Jacek P Szaflik
    Klin Oczna 107:184-5. 2005
  25. ncbi request reprint [Variability of clinical manifestations in the family with Axenfeld-Rieger syndrome]
    Anna Kaminska
    Katedry i Kliniki Okulistyki II Wydziatu Lekarskiego Akademii Medycznej w Warszawie
    Klin Oczna 109:321-6. 2007
    ..This study presents various clinical manifestations of Axenfeld-Rieger syndrome within one family...
  26. ncbi request reprint [Intraocular lens power calculation in patients after keratorefractive surgery--personal experience]
    Iwona Liberek
    Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Akademii Medycznej w Warszawie
    Klin Oczna 108:214-9. 2006
    ..To assess the efficacy of intraocular lens power calculation in patients with previous corneal refractive surgery...