M Straczkowski

Summary

Affiliation: Medical University
Country: Poland

Publications

  1. pmc Serum soluble glycoprotein 130 concentration is inversely related to insulin sensitivity in women with polycystic ovary syndrome
    Agnieszka Nikolajuk
    Department of Endocrinology, Diabetology, and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
    Diabetes 59:1026-9. 2010
  2. ncbi request reprint Serum visfatin is differentially regulated by insulin and free Fatty acids in healthy men
    Irina Kowalska
    Department of Endocrinology, Diabetology, and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    J Clin Endocrinol Metab 98:E293-7. 2013
  3. ncbi request reprint The effect of exercise training on glucose tolerance and skeletal muscle triacylglycerol content in rats fed with a high-fat diet
    M Straczkowski
    Department of Endocrinology, Medical School, Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetes Metab 27:19-23. 2001
  4. ncbi request reprint Comparison of simple indices of insulin sensitivity using the euglycemic hyperinsulinemic clamp technique
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Białystok, Poland
    Med Sci Monit 10:CR480-4. 2004
  5. ncbi request reprint Plasma interleukin-10 concentration is positively related to insulin sensitivity in young healthy individuals
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetes Care 28:2036-7. 2005
  6. ncbi request reprint Increased serum interleukin-18 concentration is associated with hypoadiponectinemia in obesity, independently of insulin resistance
    M Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
    Int J Obes (Lond) 31:221-5. 2007
  7. pmc Plasma levels of soluble tumor necrosis factor-alpha receptors are related to total and LDL-cholesterol in lean, but not in obese subjects
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M, C, Sklodowskiej 24a, 15 276 Bialystok, Poland
    Cardiovasc Diabetol 5:14. 2006
  8. ncbi request reprint Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes
    M Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetologia 50:2366-73. 2007
  9. pmc Circulating brain-derived neurotrophic factor concentration is downregulated by intralipid/heparin infusion or high-fat meal in young healthy male subjects
    Monika Karczewska-Kupczewska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
    Diabetes Care 35:358-62. 2012
  10. ncbi request reprint Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetes 53:1215-21. 2004

Collaborators

Detail Information

Publications32

  1. pmc Serum soluble glycoprotein 130 concentration is inversely related to insulin sensitivity in women with polycystic ovary syndrome
    Agnieszka Nikolajuk
    Department of Endocrinology, Diabetology, and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
    Diabetes 59:1026-9. 2010
    ..Gp130 is present in the circulation in the soluble form (sgp130), which inhibits intracellular gp130 signaling. The aim of the present study was to estimate the relation between sgp130 and insulin sensitivity in women with PCOS...
  2. ncbi request reprint Serum visfatin is differentially regulated by insulin and free Fatty acids in healthy men
    Irina Kowalska
    Department of Endocrinology, Diabetology, and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    J Clin Endocrinol Metab 98:E293-7. 2013
    ..Serum visfatin is elevated in insulin-resistant states, ie, obesity, type 2 diabetes mellitus, and polycystic ovary syndrome, thus linking visfatin with the pathogenesis of insulin resistance...
  3. ncbi request reprint The effect of exercise training on glucose tolerance and skeletal muscle triacylglycerol content in rats fed with a high-fat diet
    M Straczkowski
    Department of Endocrinology, Medical School, Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetes Metab 27:19-23. 2001
    ..0001 in all cases). We conclude that beneficial metabolic effects of training are impaired in high-fat fed rats and that training does not completely reverse metabolic disturbances in this group of animals...
  4. ncbi request reprint Comparison of simple indices of insulin sensitivity using the euglycemic hyperinsulinemic clamp technique
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University, Białystok, Poland
    Med Sci Monit 10:CR480-4. 2004
    ..Therefore, indirect indices of insulin sensitivity are proposed. The aim of the present study was to compare these simple indices with data from clamp studies...
  5. ncbi request reprint Plasma interleukin-10 concentration is positively related to insulin sensitivity in young healthy individuals
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetes Care 28:2036-7. 2005
  6. ncbi request reprint Increased serum interleukin-18 concentration is associated with hypoadiponectinemia in obesity, independently of insulin resistance
    M Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
    Int J Obes (Lond) 31:221-5. 2007
    ..The aim of the present study was to analyze the association between serum IL-18 and adiponectin in lean and obese subjects, in relation to insulin resistance...
  7. pmc Plasma levels of soluble tumor necrosis factor-alpha receptors are related to total and LDL-cholesterol in lean, but not in obese subjects
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M, C, Sklodowskiej 24a, 15 276 Bialystok, Poland
    Cardiovasc Diabetol 5:14. 2006
    ..TNFalpha is also a regulator of lipid metabolism, however, data about impact of obesity on the relationships between TNFalpha and plasma lipids remain controversial...
  8. ncbi request reprint Increased skeletal muscle ceramide level in men at risk of developing type 2 diabetes
    M Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetologia 50:2366-73. 2007
    ..The aim of our study was to assess parameters of the skeletal muscle sphingomyelin signalling pathway in men at risk of developing type 2 diabetes...
  9. pmc Circulating brain-derived neurotrophic factor concentration is downregulated by intralipid/heparin infusion or high-fat meal in young healthy male subjects
    Monika Karczewska-Kupczewska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
    Diabetes Care 35:358-62. 2012
    ..The aim of the current study was to estimate the effects of hyperinsulinemia and serum free fatty acids (FFA) elevation on circulating BDNF concentration in humans...
  10. ncbi request reprint Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Diabetes 53:1215-21. 2004
    ..68, P = 0.03) and linoleic (r = -0.66, P = 0.038) acid. Our data indicate that the sphingomyelin signaling pathway in muscle might be an important factor determining the development of insulin resistance in humans...
  11. ncbi request reprint [Assessment of insulin sensitivity during exercise training program in obese women. Comparison of simple indices with hyperinsulinemic euglycemic clamp technique]
    Marek Straczkowski
    Klinika Endokrynologii, Diabetologii i Chorób Wewnetrznych AM w Białymstoku
    Pol Arch Med Wewn 109:483-8. 2003
    ..Our study indicates that simple indices are not able to reflect changes occurring during insulin-sensitizing intervention...
  12. ncbi request reprint [Insulin resistance in obese subjects with impaired glucose tolerance. Studies with hyperinsulinemic euglycemic clamp technique]
    Marek Straczkowski
    Klinika Endokrynologii, Diabetologii i Chorób Wewnetrznych AM w Białymstoku
    Pol Arch Med Wewn 109:359-64. 2003
    ..Our study indicates that insulin resistance is an important factor determining a deterioration of glucose tolerance in subjects with overweight and obesity...
  13. ncbi request reprint Insulin resistance in the first-degree relatives of persons with type 2 diabetes
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical Academy, Białystok, Poland
    Med Sci Monit 9:CR186-90. 2003
    ..The aim of the present study was to assess insulin sensitivity in lean normoglycemic offspring of parents with type 2 diabetes...
  14. ncbi request reprint Increased plasma-soluble tumor necrosis factor-alpha receptor 2 level in lean nondiabetic offspring of type 2 diabetic subjects
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical Academy, Bialystok, Poland
    Diabetes Care 25:1824-8. 2002
    ....
  15. ncbi request reprint Changes in tumor necrosis factor-alpha system and insulin sensitivity during an exercise training program in obese women with normal and impaired glucose tolerance
    M Straczkowski
    Department of Endocrinology, Medical Academy, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Eur J Endocrinol 145:273-80. 2001
    ..The aim of the present study was to assess the effect of exercise training on the TNFalpha system and to evaluate the relationship with changes in insulin sensitivity...
  16. ncbi request reprint Serum fibroblast growth factor 21 in human obesity: regulation by insulin infusion and relationship with glucose and lipid oxidation
    M Straczkowski
    1 Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland 2 Department of Prophylaxis of Metabolic Diseases, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
    Int J Obes (Lond) 37:1386-90. 2013
    ..The aim of the present study was to assess the relationships of serum FGF21 with glucose oxidation (GOx) and lipid oxidation (LOx) in the baseline and insulin-stimulated conditions in lean and obese subjects...
  17. pmc Relationships between serum adiponectin and soluble TNF-α receptors and glucose and lipid oxidation in lean and obese subjects
    A Adamska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Poland
    Acta Diabetol 49:17-24. 2012
    ..47 and r = -0.51, respectively, both P < 0.001) in an opposite manner than adiponectin. Our data suggest that soluble TNF-α receptors and adiponectin have multiple effects on glucose and lipid metabolism in obesity...
  18. doi request reprint The FTO gene modifies weight, fat mass and insulin sensitivity in women with polycystic ovary syndrome, where its role may be larger than in other phenotypes
    I Kowalska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Poland
    Diabetes Metab 35:328-31. 2009
    ..The aim of the present study was to assess the effect of FTO variation on obesity, insulin sensitivity, and metabolic and hormonal profiles in PCOS...
  19. ncbi request reprint Plasma adiponectin and E-selectin concentrations in patients with coronary heart disease and newly diagnosed disturbances of glucose metabolism
    I Kowalska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, ul M Skłodowskiej Curie 24A, 15 276 Białystok, Poland
    Adv Med Sci 51:94-7. 2006
    ....
  20. ncbi request reprint Insulin, leptin, IGF-I and insulin-dependent protein concentrations after insulin-sensitizing therapy in obese women with polycystic ovary syndrome
    I Kowalska
    Department of Endocrinology, Medical Academy, Biaystok, Poland
    Eur J Endocrinol 144:509-15. 2001
    ..To determine the clinical, hormonal and biochemical effect of 4-5 months of insulin-sensitizing therapy (hypocaloric diet+metformin) in obese patients with polycystic ovary syndrome (PCOS)...
  21. ncbi request reprint Post-partum evaluation of amylin in lean patients with gestational diabetes mellitus
    M Kinalski
    Department of Pathophysiology of Pregnancy, Medical University in Białystok, M Curie Skłodowskiej 24 A, 15 276, Białystok, Poland
    Acta Diabetol 41:1-4. 2004
    ..Further investigations are needed to clarify the significance of this elevation as a predictive factor for the development of late maternal type 2 diabetes...
  22. ncbi request reprint Homocysteine concentrations and vascular complications in patients with type 2 diabetes
    A Rudy
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, 15 276 Białystok, ul M C Skłodowskiej 24 A, Poland
    Diabetes Metab 31:112-7. 2005
    ..The aim of the study was to evaluate the levels of homocysteine in patients with type 2 diabetes in respect to the regimen of diabetes treatment as well as the presence of diabetic complications...
  23. ncbi request reprint Plasma interleukin-8 concentrations are increased in obese subjects and related to fat mass and tumor necrosis factor-alpha system
    Marek Straczkowski
    Department of Endocrinology, Diabetology and Internal Medicine, Medical Academy, Bialystok 15 276, Poland
    J Clin Endocrinol Metab 87:4602-6. 2002
    ..We conclude that plasma IL-8 levels are increased in obese subjects, and are related to FM and TNF-alpha system. Increase in circulating IL-8 might be one of the factors linking obesity with greater cardiovascular risk...
  24. ncbi request reprint Soluble tumor necrosis factor-alpha receptors in young obese subjects with normal and impaired glucose tolerance
    Stella Dzienis-Straczkowska
    Department of Endocrinology, Academy, Bialystok, Poland
    Diabetes Care 26:875-80. 2003
    ..The aim of the present study was to assess plasma TNF-alpha, sTNFR1, and sTNFR2 levels and to evaluate the relationships with insulin resistance in obese subjects with IGT...
  25. ncbi request reprint Plasma adiponectin concentration and tumor necrosis factor-alpha system activity in lean non-diabetic offspring of type 2 diabetic subjects
    Irina Kowalska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Poland
    Eur J Endocrinol 154:319-24. 2006
    ..The aim of the study was to look for adiponectin's role in the pathogenesis of insulin resistance in offspring of type 2 diabetic patients, and its relation to the activity of the tumor necrosis factor (TNF)-alpha system...
  26. ncbi request reprint Elevated soluble intercellular adhesion molecule-1 levels in obesity: relationship to insulin resistance and tumor necrosis factor-alpha system activity
    Marek Straczkowski
    Departments of Endocrinology and Pediatric Neurology, Medical Academy, Bialystok, Poland and the Max Planck Institute for Experimental Medicine, Goettingen, Germany
    Metabolism 51:75-8. 2002
    ..We conclude that an increase in plasma sICAM-1 concentration in obesity is related to TNFalpha system activation and insulin resistance...
  27. ncbi request reprint An alternative spliced variant of circulating soluble tumor necrosis factor-alpha receptor-2 is paradoxically associated with insulin action
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Ctra França s n, 17007 Girona, Spain
    Eur J Endocrinol 154:723-30. 2006
    ..We aimed to evaluate whether this circulating DS-TNFR2 is associated with insulin action in humans...
  28. doi request reprint Serum retinol binding protein 4 is related to insulin resistance and nonoxidative glucose metabolism in lean and obese women with normal glucose tolerance
    Irina Kowalska
    Department of Endocrinology, Diabetology, and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, Bialystok, Poland
    J Clin Endocrinol Metab 93:2786-9. 2008
    ..Retinol-binding protein (RBP) 4 is secreted by adipose tissue and is postulated to be a determinant of insulin sensitivity. The mechanisms of RBP4 insulin desensitizing action remain unclear...
  29. doi request reprint Insulin resistance is associated with decreased circulating mannan-binding lectin concentrations in women with polycystic ovary syndrome
    Irina Kowalska
    Diabetes Care 31:e20. 2008
  30. ncbi request reprint Circulating E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in men with coronary artery disease assessed by angiography and disturbances of carbohydrate metabolism
    Irina Kowalska
    Department of Endocrinology, Diabetology, and Internal Medicine, Medical Academy in Białystok, Poland
    Metabolism 51:733-6. 2002
    ..27, P =.025). This would suggest that hyperglycemia increases sE-selectin and sVCAM-1 in plasma, which reflects excessive formation of atherosclerotic plaques in patients with disturbances of glucose metabolism...
  31. ncbi request reprint Serum visfatin in relation to insulin resistance and markers of hyperandrogenism in lean and obese women with polycystic ovary syndrome
    Irina Kowalska
    Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, M C Sklodowskiej 24a, 15 276 Bialystok, Poland
    Hum Reprod 22:1824-9. 2007
    ..The aim of the study was to asses the relation between serum visfatin concentration and insulin sensitivity and markers of hyperandrogenism in lean and obese PCOS patients...