M Simka

Summary

Affiliation: Medical University
Country: Poland

Publications

  1. ncbi Possible pathomechanisms responsible for injury to the central nervous system in the settings of chronic cerebrospinal venous insufficiency
    Marian Simka
    Department of Vascular and Endovascular Surgery, EUROMEDIC Specialist Clinics, Katowice, Poland
    Rev Recent Clin Trials 7:93-9. 2012
  2. ncbi Biophysics of venous return from the brain from the perspective of the pathophysiology of chronic cerebrospinal venous insufficiency
    Maciej Zaniewski
    Department of General and Vascular Surgery in Tychy, Silesian Medical University, Katowice, Poland
    Rev Recent Clin Trials 7:88-92. 2012
  3. ncbi Prevalence of extracranial venous abnormalities: results from a sample of 586 multiple sclerosis patients
    M Simka
    Department of Vascular and Endovascular Surgery, EUROMEDIC Specialist Clinics, Katowice, Poland
    Funct Neurol 26:197-203. 2011
  4. ncbi Principles and technique of foam sclerotherapy and its specific use in the treatment of venous leg ulcers
    Marian Simka
    Private Healthcare Institution SANA, Department of Angiology, Pszczyna, Poland
    Int J Low Extrem Wounds 10:138-45. 2011
  5. ncbi Extracranial Doppler sonographic criteria of chronic cerebrospinal venous insufficiency in the patients with multiple sclerosis
    M Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Int Angiol 29:109-14. 2010
  6. ncbi Cellular and molecular mechanisms of venous leg ulcers development--the "puzzle" theory
    M Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Int Angiol 29:1-19. 2010
  7. ncbi Reinterpreting the magnetic resonance signs of hemodynamic impairment in the brains of multiple sclerosis patients from the perspective of a recent discovery of outflow block in the extracranial veins
    Marian Simka
    Private Healthcare Institution SANA, Department of Angiology, Pszczyna, Poland
    J Neurosci Res 88:1841-5. 2010
  8. ncbi Seasonal variations in the onset and healing rates of venous leg ulcers
    M Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Phlebology 25:29-34. 2010
  9. ncbi Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during multiple sclerosis
    Marian Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Curr Neurovasc Res 6:132-9. 2009
  10. ncbi Hypothetical molecular mechanisms by which local iron overload facilitates the development of venous leg ulcers and multiple sclerosis lesions
    M Simka
    Department of Angiology, Wodzislawska 78, 43 200 Pszczyna, Poland
    Med Hypotheses 71:293-7. 2008

Collaborators

  • Maciej Zaniewski
  • T Ludyga
  • M Tochowicz
  • M Hartel
  • M Swierad
  • J Piegza
  • P Latacz
  • L Sedlak
  • M Kazibudzki

Detail Information

Publications16

  1. ncbi Possible pathomechanisms responsible for injury to the central nervous system in the settings of chronic cerebrospinal venous insufficiency
    Marian Simka
    Department of Vascular and Endovascular Surgery, EUROMEDIC Specialist Clinics, Katowice, Poland
    Rev Recent Clin Trials 7:93-9. 2012
    ..It is hoped that this review will help to elucidate new strategies and treatments for multiple sclerosis and will show new avenues for the research on this debilitating disease...
  2. ncbi Biophysics of venous return from the brain from the perspective of the pathophysiology of chronic cerebrospinal venous insufficiency
    Maciej Zaniewski
    Department of General and Vascular Surgery in Tychy, Silesian Medical University, Katowice, Poland
    Rev Recent Clin Trials 7:88-92. 2012
    ..This may mean that chronic cerebrospinal venous insufficiency may cause the destruction of the delicate nervous tissue of the central nervous system...
  3. ncbi Prevalence of extracranial venous abnormalities: results from a sample of 586 multiple sclerosis patients
    M Simka
    Department of Vascular and Endovascular Surgery, EUROMEDIC Specialist Clinics, Katowice, Poland
    Funct Neurol 26:197-203. 2011
    ..7%, in the left brachiocephalic vein in 1.0%, and in the azygos vein in 4.9%. Venous pathologies were found to be highly associated with MS, yet the clinical relevance of this phenomenon remains to be established...
  4. ncbi Principles and technique of foam sclerotherapy and its specific use in the treatment of venous leg ulcers
    Marian Simka
    Private Healthcare Institution SANA, Department of Angiology, Pszczyna, Poland
    Int J Low Extrem Wounds 10:138-45. 2011
    ....
  5. ncbi Extracranial Doppler sonographic criteria of chronic cerebrospinal venous insufficiency in the patients with multiple sclerosis
    M Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Int Angiol 29:109-14. 2010
    ..The aim of this open-label study was to assess extracranial Doppler criteria of chronic cerebrospinal venous insufficiency in multiple sclerosis patients...
  6. ncbi Cellular and molecular mechanisms of venous leg ulcers development--the "puzzle" theory
    M Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Int Angiol 29:1-19. 2010
    ....
  7. ncbi Reinterpreting the magnetic resonance signs of hemodynamic impairment in the brains of multiple sclerosis patients from the perspective of a recent discovery of outflow block in the extracranial veins
    Marian Simka
    Private Healthcare Institution SANA, Department of Angiology, Pszczyna, Poland
    J Neurosci Res 88:1841-5. 2010
    ..Perhaps ongoing MR studies with respect to extracranial venous hemodynamics may decipher some of the unsolved puzzles related to this neurologic disease...
  8. ncbi Seasonal variations in the onset and healing rates of venous leg ulcers
    M Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Phlebology 25:29-34. 2010
    ..As many vascular pathologies exhibit circannual fluctuation, the aim of this study was to assess the chronobiological features of venous ulcers...
  9. ncbi Blood brain barrier compromise with endothelial inflammation may lead to autoimmune loss of myelin during multiple sclerosis
    Marian Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    Curr Neurovasc Res 6:132-9. 2009
    ..We are optimistic that a hemodynamic approach to the multiple sclerosis pathogenesis can open a new chapter of investigations and treatment of this debilitating neurologic disease...
  10. ncbi Hypothetical molecular mechanisms by which local iron overload facilitates the development of venous leg ulcers and multiple sclerosis lesions
    M Simka
    Department of Angiology, Wodzislawska 78, 43 200 Pszczyna, Poland
    Med Hypotheses 71:293-7. 2008
    ..Iron chelators, administered systemically or locally, should potentially exhibit therapeutic and prophylactic activity against venous leg ulcers and multiple sclerosis...
  11. ncbi Do nonmelanoma skin cancers develop from extra-cutaneous stem cells?
    Marian Simka
    Department of Angiology, Pszczyna, Poland
    Int J Cancer 122:2173-7. 2008
    ..Hopefully, combining animal models of skin cancer initiation with experiments exploring the role of bone marrow-derived cells in skin healing will bring to light the exact mechanism of carcinogenesis of nonmelanoma skin cancers...
  12. ncbi Calf muscle pump impairment and delayed healing of venous leg ulcers: air plethysmographic findings
    Marian Simka
    Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
    J Dermatol 34:537-44. 2007
    ..Ulcers with poor prognosis according to plethysmographic findings, and no quick recovery after standard management, should be considered for advanced therapies...
  13. ncbi Delayed healing of chronic leg ulcers can result from impaired trafficking of bone marrow-derived precursors of keratinocytes to the skin
    M Simka
    Department of Angiology, ul Wodzislawska 78, 43 200 Pszczyna, Poland
    Med Hypotheses 69:637-41. 2007
    ..If this interaction were found to be the main cause of wound chronicity, above-mentioned molecules could be the potential targets for pharmaceutical agents...
  14. ncbi A potential role of interferon-gamma in the pathogenesis of venous leg ulcers
    M Simka
    Department of Angiology, ul Wodzislawska 78, 43 200 Pszczyna, Poland
    Med Hypotheses 67:639-44. 2006
    ..In such a case, anti-INFgamma agent could be used, either in the management of active ulceration, or in the prevention of recurrent ulcer...
  15. ncbi The social and economic burden of venous leg ulcers: focus on the role of micronized purified flavonoid fraction adjuvant therapy
    Marian Simka
    Out Patient Department of Angiology, Pszczyna ul Wodzislawska 78 43 200 Pszczyna, Poland
    Am J Clin Dermatol 4:573-81. 2003
    ..8 US dollars vs 1871.9 US dollars per ulcer healed). Hence, the addition of MPFF adjuvant therapy to the treatment of venous leg ulcers would be effective and potentially cost saving...
  16. ncbi Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe?
    T Ludyga
    EUROMEDIC Specialist Clinics, Department of Vascular and Endovascular Surgery, Katowice, Poland
    Phlebology 25:286-95. 2010
    ..Although balloon angioplasty and stenting seem to be safe procedures, there are currently no data on the treatment of a large group of patients with this vascular pathology...