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Affiliation: Medical University of Silesia
Sułkowski L, Pawełczak B, Chudzik M, Maciążek Jurczyk M. Characteristics of the Protoporphyrin IX Binding Sites on Human Serum Albumin Using Molecular Docking. Molecules. 2016;21: pubmed
..In summary, fluorescent studies on binding interactions between HSA and PpIX have been confirmed by the results of computer simulation. ..
Chudzik M, Maciążek Jurczyk M, Pawełczak B, Sułkowska A. Spectroscopic Studies on the Molecular Ageing of Serum Albumin. Molecules. 2016;22: pubmed publisher
..Based on the spectrofluorescence study, the alterations in metoprolol binding affinity to the specific sites that increase the toxicity of the drug were investigated. ..
Marciniec K, Pawełczak B, Latocha M, Skrzypek L, Maciążek Jurczyk M, Boryczka S. Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives. Molecules. 2017;22: pubmed publisher
..These data indicate that some of the title compounds display significant cytotoxic activity, possibly targeting the CYPs pathways. ..