Grzegorz Opolski

..The relative risks and benefits of strategies of rate control vs rhythm control in patients with atrial fibrillation (AF) remain to be fully explored...

..TIMI risk score for ST elevation acute myocardial infarction (STEMI) and Killip classes are simple tools for early risk stratification...

..We sought to determine whether platelet reactivity predicts impaired myocardial reperfusion, left ventricular (LV) dysfunction, and clinical events in an unselected group of patients with STEMI...

..To assess the relation between B-type natriuretic peptide (BNP) levels on admission in ST elevation myocardial infarction (STEMI) and short-term, all-cause mortality...

..The aim was to determine the frequency and clinical significance of inadequate inhibition of two major platelet activation pathways: the thromboxane A2 (TXA2)- and ADP-dependent, in the early phase of STEMI...

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..The term "ASA resistance" has been used to describe not only the lack of expected pharmacologic effects of ASA on platelets but also poor clinical outcomes, such as recurrent vascular events, in patients treated with ASA...

..According to the new universal definition of myocardial infarction patient was finally recognized acute ST-segment elevation myocardial infarction type 4b with additional diagnosis of severe obstructive sleep apnea and overweight...

..CONCLUSIONS: Successful cardioversion of persistent AF resulted in a significant improvement of exercise capacity and a decrease in heart failure symptoms during one year follow-up period only in patients who maintained SR...

..Although patients with SR had better improvement in some haemodynamical parameters, the hospitalisation rate was higher and the incidence of stroke was not reduced compared with the rate control group...

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..83; 95% confidence interval: 1.03-2.95; P < 0.01). Of all the considered variables only LA area and FS value seem to be relatively reliable predictors of SR sustainability at 1 year after an effective cardioversion of persistent AF...

..A prospective, randomized study was conducted to evaluate the efficacy and tolerability of oral propafenone and quinidine for the conversion of paroxysmal atrial fibrillation (AF)...

..12-0.77, p = 0.012). In conclusion, low PR to ADP is associated with increased hazard of bleeding and poses similar combined risk of bleeding and ischemic events as high PR. Medium PR predicts favorable net outcome in ACS patients...

..The aim of our study was to determine differences in prognosis between patients with CA before, during, and after PCI...

..To that effect we conducted detailed analysis of the related costs and other relevant data collected in the course of the HOT CAFE study...

..Prevalence of borderline ECG changes in patients with acute coronary occlusion confirms how important is precise ECG interpretation usually initially done by ED physician...

..We sought to evaluate the impact of baseline platelet indices on the occurrence of early ST and future residual platelet reactivity...

..Genetic C3435T polymorphism of the multidrug resistance gene-1 (MDR-1) limits oral bioavailability of clopidogrel and influences prognosis in patients with myocardial infarction...

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..The RecordAF study is the first worldwide, prospective, observational survey on the management of patients with recently diagnosed atrial fibrillation (AF)...

..6% for patients with nonpositive marker, 3.4% for patients with 1 positive marker, and 11.5% for patients with at least 2 positive markers (P = .001 for trend)...

..Secondary objectives included overall survival (OS) and safety...

..Takotsubo cardiomyopathy (TTC) is a rare transient cardiomyopathy mimicking acute coronary syndrome (ACS)...

..The aim of the study was to analyse the prognostic implications of 3 myocardial necrosis markers measured at admission in the long-term observation...

..The study was designed to determine whether impaired antiplatelet response to clopidogrel but not to aspirin may be responsible for loss of pleiotropic effects of the drug...

..Little data exists regarding the recurrence of the disease, especially over the long-term follow-up. We present a case of relapse of LVAB after ten years...

..Cryoballon isolation of the pulmonary veins has recently emerged as a promissing technique for ablation of atrial fibrillation (AF)...

..Genome-wide studies have shown that polymorphisms on chromosome 4q25, 16q22 and 1q21 correlate with atrial fibrillation (AF). However, the distribution of these polymorphisms differs significantly among populations...

..Obstructive sleep apnea (OSA) is associated with several cardiovascular conditions such as hypertension, ischemic heart disease, arrhythmias, and erectile dysfunction (ED)...

..BNP elevation is probably associated with hemodynamical stress caused by transient contractility abnormalities. Diagnostic and prognostic role of BNP in acute perimyocarditis requires further studies...

..In more severe cases, the hemodynamic alterations can result in heart failure...

..The findings contradict other opinions that trastuzumab-related acute heart failure is analogous to stunning or hibernation and recovers without specific cardiac treatment...

..CONCLUSIONS: Left atrial area and left ventricular fractional shortening are the independent predictors of the maintenance of SR after successful CV in patients with persistent AF...

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..This prospective study evaluates the efficacy of sequential antiarrhythmic drug therapy in sinus rhythm (SR) maintenance after successful elective CV in patients with persistent nonvalvular AF...

..The complex pathomechanism of FIMR and its dynamic nature make it difficult to develop effective therapeutic methods...

..Electrical storm (ES) is a life-threatening condition requiring prompt and effective therapy. This may be achieved by the use of catheter ablation...

..Studies on the neurohormonal remodelling in patients with AF are becoming increasingly important because they may improve the treatment of AF...

..No therapy has been proved to be beneficial for patients with heart failure and preserved ejection fraction (PLVEF)...

..Aim: To evaluate the influence of sinus rhythm restoration on ANP and BNP levels in patients with normal and impaired LV diastolic function...

..Therefore we sought to determine U-II dynamics during exercise in myocardial infarction survivors with and without hypertension...

..The aim of our study was to establish gene expression patterns in leukocytes from acute myocardial infarction patients...

..Ablation of atrial fibrillation (AF) can be difficult and time-consuming. Systems facilitating catheter navigation may be helpful...

..Conversion to SR was associated with a significant decrease and normalization in plasma ANP concentrations...

..We sought to determine whether continuation of aspirin until surgery day suppresses platelet activity in the early period after off-pump coronary artery bypass grafting (OPCAB)...

..Strict selection criteria and the choice of the device may help reduce the incidence of complications such as dislocation of the occluder into the right atrium following the percutaneous device closure of an atrial septal defect...

..We present a practical application of real time three-dimensional transesophageal echocardiography in a 67-year-old male patient with congenital heart disease...

..Few data are available for BNP levels obtained on admission in patients with acute ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI)...

..Future studies of blood-cell transcriptomic profiles in patients with AHF will provide further insights into the molecular pathogenesis of this cardiorenal disorder...

..In this article, we report the first Polish experience of two successful TAVI procedures with bioprostheses (both balloon- and self-expandable) delivered using direct aortic access...

..The aim of our study was to characterize specific tissue reaction of encapsulating lead tissue in patients who underwent transvenous lead removal and evaluate condition of the outer leads' insulation...

..Adiponectin levels are decreased in patients with cardiovascular diseases and type 2 diabetes (DM)...

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..The aim of the study was to evaluate the influence of periodontal disease on the intensity and dynamics of the inflammatory response in patients with acute coronary syndrome and coexistent periodontal diseases...

..We present the real-time three-dimensional echocardiography in a patient who suffered a transient left apical ballooning syndrome...

..The purpose of this study was to evaluate left atrial mechanical function recovery and plasma atrial natriuretic peptide (ANP) release following successful cardioversion of persistent atrial fibrillation (AF)...

..Plasma ANP concentrations were independent of echocardiographic measurements of LA size or LV size and function in patients with persistent AF...

..45, P < 0.02 for Myo and r = 0.47, P = 0.01 for cTnI). It is concluded that in cardioversion of AF, biphasic are more effective than monophasic and may cause less myocardial injury...

..We also found an increased B-type natriuretic peptide level in this patent--the finding not reported previously in the literature...

..More research is also needed to assess the efficacy of pharmacogenetic treatment methods for atrial fibrillation...

..Amiodarone seems to be the most effective antiarrhythmic drug also in pts who required a second CV proceeded by amiodarone treatment to restore SR...

..In recent years large scale clinical trials have cleary shown that a number of pharmacological treatments can improve the outcomes of patients (pts) with chronic heart failure (CHF)...

..Recommendation given by an expert system can be reliable. At present the system is tested in clinical practice. Strategies recommended by the system are compared to the management applied in patients treated in Cardiology Clinic...

..Ischaemic mitral regurgitation (IMR) may be surgically treated by isolated myocardial revascularisation or in combination with valve repair. Dobutamine stress echocardiography (DSE) may be helpful in selecting an optimal surgical strategy...

..Renal function assessment is an important element of management and therapeutic decision-making in patients with chronic heart failure (CHF)...

..Aim of our study was to determine the dynamics of selected echocardiographic parameters after sinus rhythm (SR) restoration and maintenance in pts with persistent nonvalvular atrial fibrillation (AF) during one year follow-up period...

..To assess the safety and efficacy of amiodarone used after unsuccessful direct current (DC) cardioversion of persistent atrial fibrillation (AF)...

..Secondly paradoxically--they were less often prescribed with antiplatelet drugs, statins, beta-blockers and ACE inhibitors. Thus theory do not translate into practice...

..Persistent platelet function while on antiplatelet therapy affects outcomes in patients with acute coronary syndromes (ACS)...

..The article summarizes some new investigations into ancillary properties of carvedilol which may decide of its special position among beta-adrenolytices used in heart failure...

..However, the patient died due to intractable cardiogenic shock...

..This study was performed to establish the prevalence of high platelet reactivity (HPR) on ASA in T2DM and to identify its predictors...

..Large, randomised studies documented the role of angiotensin-converting enzyme inhibitors (ACE-I) and beta-blockers in the reduction of mortality and morbidity in CHF...

..Leptin is associated with development of type 2 diabetes and cardiovascular disease. Aim: To evaluate leptin concentrations in acute myocardial infarction and in the period of convalescence in patients with type 2 diabetes mellitus...

..Therefore, the ERC recommends providing AED in public locations with a high incidence of cardiac arrests...

..Cardiac MC degranulation after myocardial ischemia has been documented in animal models. Cardiac MCs are highly profibrinolytic cells and release tryptase, their specific protease, after ischemic events...

..The function of vascular endothelium is influenced by several factors: low-density lipoprotein (LDL) cholesterol, oxidative stress and the reninangiotensin system...

..Further studies are required to confirm the utility of sunitinib therapy in patients with symptoms of heart failure due to heart metastases from RCC...

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..To evaluate periodontal disease (PD) influence on changes in high-sensitivity C-reactive protein (hsCRP) concentrations in patients with acute coronary syndromes and coexistent PD...

..Although there is no test recommended to assess the response to the antiplatelet therapy, the presented case suggests platelet function analysis should be undertaken in patients with recurrent stent thrombosis...

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..of spontaneous events of symptomatic PAF with and without anti-arrhythmic medication? (2) what is the prevalence of severe side-effects? and (3) is the fixed combination of Quinidine + Verapamil inferior to the efficacy of sotalol or not?..

..BNP levels correlated negatively with left ventricular ejection fraction. Increase in BNP levels in apical ballooning syndrome may support the neurohormonal etiology in these patients and requires further studies...

..Coexisting polymorphisms of the genes affecting clopiogrel resistance may influence platelet activation...

..Follow-up angiography and IVUS show a complete resolution of thrombus. The article discusses different management strategies in patients with confirmed ruptured plaque in LMCA...

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..Electrophysiological examination revealed the presence of an accessory pathway with a negative delta wave in inferior leads mimicking pathological Q wave. Differential diagnosis of pathological Q waves is discussed...

..The chart reviews were performed. Coronary angiography did not reveal the occlusion of the coronary artery. Radiography, echocardiography, and multislice computed tomography confirmed newly diagnosed ccTGA...

..Next, platelet activity was monitored using the platelet function analyser PFA-100 which enabled optimisation of the antiplatelet agent dosages. The usefulness of this device in the catheterisation laboratory is discussed...

..The highest compliance between declarations from questionnaire and clinical practice concerned the use of BB and ACE-I combination...

..There is a conclusion that biphasic shock used during CV of AF is more efficient and may cause less myocardial and skeletal muscle damage due to lower energy delivered...

..This provided a possibility for hospitals to apply current standards of care to patients with acute coronary syndromes (ACS)...