Robert Marek Mroz

Summary

Affiliation: Medical University
Country: Poland

Publications

  1. pmc Increased levels of Treg cells in bronchoalveolar lavage fluid and induced sputum of patients with active pulmonary sarcoidosis
    R M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 14:165-9. 2009
  2. ncbi request reprint Lung mass in a 28-year-old male: a case report of a rare tumor
    Robert M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 15:95-7. 2010
  3. doi request reprint Siglec-8 in induced sputum of COPD patients
    R M Mroz
    Department of Chest Diseases and Tuberculosis, Bialystok Medical University, 14 Zurawia St, Bialystok, Poland
    Adv Exp Med Biol 788:19-23. 2013
  4. doi request reprint sVEGF R1 and Tie-2 levels during chemotherapy of lung cancer patients
    R M Mroz
    Department of Lung Diseasess, Bialystok Medical University, Bialystok, Poland
    Adv Exp Med Biol 756:313-9. 2013
  5. doi request reprint Indacaterol add-on therapy improves lung function, exercise capacity and life quality of COPD patients
    R M Mroz
    Department of Lung Diseases, Medical University of Bialystok, Zurawia 14, Bialystok, Poland
    Adv Exp Med Biol 756:23-8. 2013
  6. ncbi request reprint Increased levels of interleukin-12 and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 59:507-13. 2008
  7. pmc Dermatomyositis masquerading as pulmonary embolism
    R M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 14:162-4. 2009
  8. ncbi request reprint Churg-Strauss syndrome: a case report
    Robert M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 15:92-4. 2010
  9. ncbi request reprint [Treatment of chronic obstructive pulmonary disease--traditional bronchodilatation and targeted anti-inflammatory therapy]
    Robert M Mroz
    Klinika Chorób Płuc i Gruźlicy Uniwersytetu Medycznego w Białymstoku
    Pneumonol Alergol Pol 79:32-8. 2011
  10. ncbi request reprint Upregulation of Th1 cytokine profile in bronchoalveolar lavage fluid of patients with hypersensitivity pneumonitis
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 59:499-505. 2008

Detail Information

Publications20

  1. pmc Increased levels of Treg cells in bronchoalveolar lavage fluid and induced sputum of patients with active pulmonary sarcoidosis
    R M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 14:165-9. 2009
    ..It has recently been described that circulatory and BAL regulatory T-cells (Tregs), defined as CD4+CD25highCD127low are increased in patients with active sarcoidosis compared with other interstitial lung diseases...
  2. ncbi request reprint Lung mass in a 28-year-old male: a case report of a rare tumor
    Robert M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 15:95-7. 2010
    ..Patient underwent chemotherapy with 5-FU/DDP/VCR with no response. This report presents a case of a rare lung metastasis from FL-HCC...
  3. doi request reprint Siglec-8 in induced sputum of COPD patients
    R M Mroz
    Department of Chest Diseases and Tuberculosis, Bialystok Medical University, 14 Zurawia St, Bialystok, Poland
    Adv Exp Med Biol 788:19-23. 2013
    ..15,000 Adj. Vol. INT/mm(2). Our data show that Siglec-8 may be involved in COPD pathogenesis and may influence COPD phenotyping. ..
  4. doi request reprint sVEGF R1 and Tie-2 levels during chemotherapy of lung cancer patients
    R M Mroz
    Department of Lung Diseasess, Bialystok Medical University, Bialystok, Poland
    Adv Exp Med Biol 756:313-9. 2013
    ..5 vs. 25.7 (p < 0.001) in SCLC and N-SCLC, respectively. We conclude that VEGF R1and Tie-2 receptors may play important role in lung cancer development and their receptor concentrations may reflect the patients' response to treatment...
  5. doi request reprint Indacaterol add-on therapy improves lung function, exercise capacity and life quality of COPD patients
    R M Mroz
    Department of Lung Diseases, Medical University of Bialystok, Zurawia 14, Bialystok, Poland
    Adv Exp Med Biol 756:23-8. 2013
    ..The patients' quality of life also changed favorably in the indacaterol treatment arm. We conclude that the add-on therapy with indacaterol exerts positive effects in COPD patients...
  6. ncbi request reprint Increased levels of interleukin-12 and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 59:507-13. 2008
    ..A negative correlation between BALF IL-12 and ACE plasma levels (r=-0.33, P<0.05) within the sarcoidosis group was found. Our data suggest a potential role of IL-12 and IL-18 in a local immunologic response in pulmonary sarcoidosis...
  7. pmc Dermatomyositis masquerading as pulmonary embolism
    R M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 14:162-4. 2009
    ..The patient was started on solumedrol 40 mg i.v., b.i.d., and then switched to prednisone 40 mg b.i.d. His symptoms and muscle strength improved remarkably. The patient was discharged with prednisone with an outpatient follow up...
  8. ncbi request reprint Churg-Strauss syndrome: a case report
    Robert M Mroz
    Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland
    Eur J Med Res 15:92-4. 2010
    ..After one month of therapy skin lesions regressed. After 18 months of the treatment patient reports no signs, nor symptoms of the disease. Patient continues oral corticosteroid therapy...
  9. ncbi request reprint [Treatment of chronic obstructive pulmonary disease--traditional bronchodilatation and targeted anti-inflammatory therapy]
    Robert M Mroz
    Klinika Chorób Płuc i Gruźlicy Uniwersytetu Medycznego w Białymstoku
    Pneumonol Alergol Pol 79:32-8. 2011
    ..The authors analize currently available treatment modalities with regards to their potential anti-inflammatory and pleiotropic mode of action, which may lead to disease course modification...
  10. ncbi request reprint Upregulation of Th1 cytokine profile in bronchoalveolar lavage fluid of patients with hypersensitivity pneumonitis
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 59:499-505. 2008
    ..68, P=0.015) and a negative one between IL-12 and the percentage of macrophages in BALF (r=-0.64, P=0.024). We conclude that upregulation of the Th1 cell cytokine profile may play a significant role in the pathogenesis of HP...
  11. ncbi request reprint Severe respiratory distress caused by central airway obstruction treated with self-expandable metallic stents
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 59:491-7. 2008
    ..The mean follow-up was 65 (5 to 752) days. SEMS are useful for the treatment of SRD caused by CAO. The overall effect is related to the degree of tumor progression itself...
  12. ncbi request reprint [Stenting central airways with tracheobronchial stents]
    Robert M Mroz
    Z Kliniki Chorób Płuc i Gruźlicy Akademii Medycznej w Białymstoku
    Wiad Lek 59:246-9. 2006
    ..The choice of the type of the stent used is made on the basis of personnel experience, type and localisation of the obstruction, clinical status and accompanying diseases...
  13. ncbi request reprint Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways
    R M Mroz
    ELEGI Colt Laboratories, University of Edinburgh, Edinburgh, Scotland, UK
    Eur Respir J 31:241-51. 2008
    ..In conclusion, nanoparticles and reactive oxidative species induce DNA damage, activating p53 and proteins related to DNA repair, mimicking irradiation-related carcinogenesis pathways...
  14. ncbi request reprint [Histone dependent signalization during pharmacotherapy of chronic obstructive pulmonary disease]
    Robert Marek Mroz
    Klinika Chorób Płuc i Gruźlicy Akademii Medycznej w Białymstoku, ul Zurawia 14, 15 540 Białystok, Poland
    Pneumonol Alergol Pol 75:375-82. 2007
    ..However, further studies are necessary to confirm these findings...
  15. ncbi request reprint Cytoplasm-nuclear trafficking of CREB and CREB phosphorylation at Ser133 during therapy of chronic obstructive pulmonary disease
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 58:437-44. 2007
    ..In F/ICS-treated patients, relative accumulation of CREB in cytosol was observed. These findings indicate, that poor response to ICS therapy may be related to increased CREB-associated signaling...
  16. ncbi request reprint Comparison of induced sputum and bronchoalveolar lavage fluid cell profile during the treatment of pulmonary sarcoidosis
    R M Mroz
    Department of Pulmonology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 58:445-52. 2007
    ..59), CD8+ (r=0.34), CD4/CD8 ratio (r= 0.66) and CD3+ HLA-DR+ (r=0.89) cell population. These finding suggest that IS may serve as a valuable alternative to BAL technique...
  17. ncbi request reprint Molecular basis of chronic inflammation in lung diseases: new therapeutic approach
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 58:453-60. 2007
    ..Several new strategies to control inflammations in COPD, aiming at restoration of the HDAC-2 activity and/or mitigation of HAT-related signaling are in the preclinical and clinical development...
  18. ncbi request reprint Nanoparticle carbon black driven DNA damage induces growth arrest and AP-1 and NFkappaB DNA binding in lung epithelial A549 cell line
    R M Mroz
    ELEGI Colt Laboratories, MRC University of Edinburgh Center for Inflammation Research, Edinburgh, UK
    J Physiol Pharmacol 58:461-70. 2007
    ..N-acetylcysteine blocked NP driven effects. In conclusion, NPCB and BaP-NPCB induce DNA damage, activating p53, proteins related to DNA repair and proinflammatory transcription factors...
  19. ncbi request reprint Chronic obstructive pulmonary disease: an update on nuclear signaling related to inflammation and anti-inflammatory treatment
    R M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    J Physiol Pharmacol 59:35-42. 2008
    ..In this review, the authors gave a short update on the recent hypothesis and findings that may imply novel approach to pharmacotherapy of the disease, focusing on the role of glucocorticosteroids, theophylline, and antioxidants...
  20. ncbi request reprint p53 N-terminal Ser-15 approximately P and Ser-20 approximately P levels in squamous cell lung cancer after radio/chemotherapy
    Robert M Mroz
    Department of Pneumology, Bialystok Medical University, Bialystok, Poland
    Am J Respir Cell Mol Biol 30:564-8. 2004
    ....