Krzysztof Marciniec


Affiliation: Medical University of Silesia
Country: Poland


  1. Bębenek E, Chrobak E, Marciniec K, Kadela Tomanek M, Trynda J, Wietrzyk J, et al. Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde. Int J Mol Sci. 2019;20: pubmed publisher
    ..38 Ų and 55.77 Ų suggesting high oral bioavailability. The molecular docking calculations showed that triterpene 9 fits the active site of the serine/threonine protein kinase Akt. ..
  2. Marciniec K, Kurczab R, Książek M, Bębenek E, Chrobak E, Satała G, et al. Structural determinants influencing halogen bonding: a case study on azinesulfonamide analogs of aripiprazole as 5-HT1A, 5-HT7, and D2 receptor ligands. Chem Cent J. 2018;12:55 pubmed publisher
    ..Molecular docking studies indicate the role of halogen bonding in complexes of the most potent ligands and target receptors. ..
  3. Marciniec K, Pawełczak B, Latocha M, Skrzypek L, Maciążek Jurczyk M, Boryczka S. Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives. Molecules. 2017;22: pubmed publisher
    ..These data indicate that some of the title compounds display significant cytotoxic activity, possibly targeting the CYPs pathways. ..