Genomes and Genes


Małgorzata Maciążek Jurczyk


Affiliation: Medical University of Silesia
Country: Poland


  1. Szkudlarek A, Pożycka J, Maciążek Jurczyk M. Influence of Piracetam on Gliclazide-Glycated Human Serum Albumin Interaction. A Spectrofluorometric Study. Molecules. 2018;24: pubmed publisher
    ..Based on the obtained data we concluded that monitoring therapy and precautions are required in the treatment when the combinations of gliclazide and piracetam are used at the same time. ..
  2. Maciążek Jurczyk M, Sułkowska A. Spectroscopic analysis of the impact of oxidative stress on the structure of human serum albumin (HSA) in terms of its binding properties. Spectrochim Acta A Mol Biomol Spectrosc. 2015;136 Pt B:265-82 pubmed publisher
  3. Maciążek Jurczyk M, Sułkowska A, Równicka Zubik J. Alteration of methotrexate binding to human serum albumin induced by oxidative stress. Spectroscopic comparative study. Spectrochim Acta A Mol Biomol Spectrosc. 2016;152:537-50 pubmed publisher
    ..For these systems, qualitative analysis in the low affinity binding sites was performed with the use of the (1)HNMR technique. ..
  4. request reprint
    Maliszewska M, Maciążek Jurczyk M, Pożycka J, Szkudlarek A, Chudzik M, Sułkowska A. Fluorometric Investigation on the Binding of Letrozole and Resveratrol with Serum Albumin. Protein Pept Lett. 2016;23:867-877 pubmed
    ..This conclusion points to the necessity of precaution and monitoring therapy when resveratrol as a natural compound and letrozole are used together. ..
  5. Sułkowski L, Pawełczak B, Chudzik M, Maciążek Jurczyk M. Characteristics of the Protoporphyrin IX Binding Sites on Human Serum Albumin Using Molecular Docking. Molecules. 2016;21: pubmed
    ..In summary, fluorescent studies on binding interactions between HSA and PpIX have been confirmed by the results of computer simulation. ..
  6. Chudzik M, Maciążek Jurczyk M, Pawełczak B, Sułkowska A. Spectroscopic Studies on the Molecular Ageing of Serum Albumin. Molecules. 2016;22: pubmed publisher
    ..Based on the spectrofluorescence study, the alterations in metoprolol binding affinity to the specific sites that increase the toxicity of the drug were investigated. ..
  7. Marciniec K, Pawełczak B, Latocha M, Skrzypek L, Maciążek Jurczyk M, Boryczka S. Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives. Molecules. 2017;22: pubmed publisher
    ..These data indicate that some of the title compounds display significant cytotoxic activity, possibly targeting the CYPs pathways. ..
  8. Szkudlarek A, Pentak D, Ploch A, Pożycka J, Maciążek Jurczyk M. Effect of Temperature on Tolbutamide Binding to Glycated Serum Albumin. Molecules. 2017;22: pubmed publisher
    ..This information may lead to the development of more effective drug therapy in people with diabetes. ..
  9. Maciążek Jurczyk M, Szkudlarek A, Chudzik M, Pożycka J, Sułkowska A. Alteration of human serum albumin binding properties induced by modifications: A review. Spectrochim Acta A Mol Biomol Spectrosc. 2018;188:675-683 pubmed publisher