Research Topics
| W LeppertSummaryAffiliation: Medical University Country: Poland Publications
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Detail Information
Publications
The Adaptation of the Sheffield Profile for Assessment and Referral for Care (SPARC) to the Polish Clinical Setting for Needs Assessment of Advanced Cancer PatientsWojciech Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland Electronic address
J Pain Symptom Manage 44:916-22. 2012..Assessment of the needs of advanced cancer patients is a very important issue in palliative care...
Quality of life in patients with advanced lung cancer treated at home and at a palliative care unitWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
Am J Hosp Palliat Care 29:379-87. 2012..To assess quality of life (QOL) in patients with advanced lung cancer...
The role of corticosteroids in the treatment of pain in cancer patientsWojciech Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
Curr Pain Headache Rep 16:307-13. 2012..This review aims to present the role of steroids in pain and management of other symptoms in cancer patients according to the available data, and discusses practical aspects of steroid use...
Analgesia and serum assays of controlled-release dihydrocodeine and metabolites in cancer patients with painWojciech Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
Pharmacol Rep 64:84-93. 2012..Few significant correlations were found between DHC dose, DHC and metabolites serum concentrations with analgesia suggesting the individual DHC dose titration...
CYP2D6 in the metabolism of opioids for mild to moderate painWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
Pharmacology 87:274-85. 2011..The aim of this review is to summarize data on the impact of CYP2D6 polymorphism on pharmacokinetics, pharmacodynamics and adverse effects of weak opioids...
Pain management in patients with cancer: focus on opioid analgesicsWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
Curr Pain Headache Rep 15:271-9. 2011..Understanding the pharmacokinetics, pharmacodynamics, interactions, and cautions with commonly used opioids can help determine appropriate opioid selection for individual cancer patients...
Analgesic effects and assays of controlled-release tramadol and o-desmethyltramadol in cancer patients with painWojciech Leppert
Poznan University of Medical Sciences, Osiedle Rusa 25A, 61 245 Poznan, Poland
Curr Pharm Biotechnol 12:306-12. 2011..To assess tramadol and O-desmethyltramadol (M1) concentrations and their correlations with analgesia in patients with cancer pain...
The impact of tramadol and dihydrocodeine treatment on quality of life of patients with cancer painW Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
Int J Clin Pract 64:1681-7. 2010..The aim of the study was to assess the impact of tramadol and DHC treatment on quality of life (QL) and performance status (PS) of patients with cancer pain...
Role of oxycodone and oxycodone/naloxone in cancer pain managementWojciech Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
Pharmacol Rep 62:578-91. 2010..The potential role of oxycodone/naloxone in chronic pain management and its impact on the bowel function is also discussed...
The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a reviewWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
Adv Ther 27:714-30. 2010..On the other hand, uncontrolled OIC and the necessity to perform rectal invasive procedures (enema, manual evacuation) lead not only to increased health care costs, but most importantly, cause severe patient suffering...
Polish brief pain inventory for pain assessment and monitoring of pain treatment in patients with cancerWojciech Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
J Palliat Med 13:663-8. 2010..To adapt the Brief Pain Inventory-Short Form (BPI-SF) to Polish and to evaluate its psychometric properties (validity and reliability) in patients with cancer pain and to use BPI-SF for pain assessment and monitoring of pain treatment...
Dihydrocodeine as an opioid analgesic for the treatment of moderate to severe chronic painWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
Curr Drug Metab 11:494-506. 2010..The impact of CYP2D6 activity on DHC analgesia was discussed and a proposal of calculation equianalgesic doses of DHC to other opioids was put forward...
Tramadol as an analgesic for mild to moderate cancer painWojciech Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
Pharmacol Rep 61:978-92. 2009....
The role of methadone in cancer pain treatment--a reviewW Leppert
Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
Int J Clin Pract 63:1095-109. 2009..Methadone is an opioid analgesic of step 3 of the World Health Organization (WHO) analgesic ladder...
The role of methadone in opioid rotation-a Polish experienceWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, Poznan 61 245, Poland
Support Care Cancer 17:607-12. 2009..To assess methadone analgesia, adverse effects, and calculation method of equianalgesic doses with oral morphine...
The role of tramadol in cancer pain treatment--a reviewWojciech Leppert
Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
Support Care Cancer 13:5-17. 2005..In this article we summarize data on pharmacology, mechanisms of action, pharmacokinetics, side effects and clinical experience assessing analgesic efficacy, adverse reactions and safety of tramadol in cancer pain...
