W Leppert

Summary

Affiliation: Medical University
Country: Poland

Publications

  1. ncbi request reprint Oxycodone/Naloxone in the management of patients with pain and opioid-induced bowel dysfunction
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245 Poznan, Poland
    Curr Drug Targets 15:124-35. 2014
  2. ncbi request reprint Delivery systems of opioid analgesics for pain relief: a review
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245 Poznan, Poland
    Curr Pharm Des 19:7271-93. 2013
  3. pmc Attitudes of Polish physicians and medical students toward breaking bad news, euthanasia and morphine administration in cancer patients
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
    J Cancer Educ 28:603-10. 2013
  4. pmc A comparison of attitudes toward euthanasia among medical students at two Polish universities
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
    J Cancer Educ 28:384-91. 2013
  5. doi request reprint Validation of the Polish version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 15 - Palliative Care in patients with advanced cancer
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Palliat Med 27:470-7. 2013
  6. doi request reprint The adaptation of the Sheffield Profile for Assessment and Referral for Care (SPARC) to the Polish clinical setting for needs assessment of advanced cancer patients
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    J Pain Symptom Manage 44:916-22. 2012
  7. doi request reprint Quality of life in patients with advanced lung cancer treated at home and at a palliative care unit
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Am J Hosp Palliat Care 29:379-87. 2012
  8. pmc The role of corticosteroids in the treatment of pain in cancer patients
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
    Curr Pain Headache Rep 16:307-13. 2012
  9. ncbi request reprint Analgesia and serum assays of controlled-release dihydrocodeine and metabolites in cancer patients with pain
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
    Pharmacol Rep 64:84-93. 2012
  10. doi request reprint CYP2D6 in the metabolism of opioids for mild to moderate pain
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacology 87:274-85. 2011

Detail Information

Publications21

  1. ncbi request reprint Oxycodone/Naloxone in the management of patients with pain and opioid-induced bowel dysfunction
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245 Poznan, Poland
    Curr Drug Targets 15:124-35. 2014
    ..Conclusion: OXN is an important drug for chronic pain management, prevention and treatment of OIBD. ..
  2. ncbi request reprint Delivery systems of opioid analgesics for pain relief: a review
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245 Poznan, Poland
    Curr Pharm Des 19:7271-93. 2013
    ..Alternative routes comprise rectal, inhaled and topical administration of opioids. This article discusses various routes of opioid administration. ..
  3. pmc Attitudes of Polish physicians and medical students toward breaking bad news, euthanasia and morphine administration in cancer patients
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
    J Cancer Educ 28:603-10. 2013
    ..In contrast to medical students, the majority of physicians have knowledge concerning chronic morphine use in the treatment of cancer patients...
  4. pmc A comparison of attitudes toward euthanasia among medical students at two Polish universities
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
    J Cancer Educ 28:384-91. 2013
    ..Gender and religion influenced students' answers. Differences observed between medical students at the two universities might be related to gender and cultural differences...
  5. doi request reprint Validation of the Polish version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 15 - Palliative Care in patients with advanced cancer
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Palliat Med 27:470-7. 2013
    ..Limited data exist on the validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Core 15 - Palliative Care in advanced cancer patients...
  6. doi request reprint The adaptation of the Sheffield Profile for Assessment and Referral for Care (SPARC) to the Polish clinical setting for needs assessment of advanced cancer patients
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    J Pain Symptom Manage 44:916-22. 2012
    ..Assessment of the needs of advanced cancer patients is a very important issue in palliative care...
  7. doi request reprint Quality of life in patients with advanced lung cancer treated at home and at a palliative care unit
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Am J Hosp Palliat Care 29:379-87. 2012
    ..To assess quality of life (QOL) in patients with advanced lung cancer...
  8. pmc The role of corticosteroids in the treatment of pain in cancer patients
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
    Curr Pain Headache Rep 16:307-13. 2012
    ..This review aims to present the role of steroids in pain and management of other symptoms in cancer patients according to the available data, and discusses practical aspects of steroid use...
  9. ncbi request reprint Analgesia and serum assays of controlled-release dihydrocodeine and metabolites in cancer patients with pain
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
    Pharmacol Rep 64:84-93. 2012
    ..Few significant correlations were found between DHC dose, DHC and metabolites serum concentrations with analgesia suggesting the individual DHC dose titration...
  10. doi request reprint CYP2D6 in the metabolism of opioids for mild to moderate pain
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Pharmacology 87:274-85. 2011
    ..The aim of this review is to summarize data on the impact of CYP2D6 polymorphism on pharmacokinetics, pharmacodynamics and adverse effects of weak opioids...
  11. pmc Pain management in patients with cancer: focus on opioid analgesics
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
    Curr Pain Headache Rep 15:271-9. 2011
    ..Understanding the pharmacokinetics, pharmacodynamics, interactions, and cautions with commonly used opioids can help determine appropriate opioid selection for individual cancer patients...
  12. ncbi request reprint Analgesic effects and assays of controlled-release tramadol and o-desmethyltramadol in cancer patients with pain
    Wojciech Leppert
    Poznan University of Medical Sciences, Osiedle Rusa 25A, 61 245 Poznan, Poland
    Curr Pharm Biotechnol 12:306-12. 2011
    ..To assess tramadol and O-desmethyltramadol (M1) concentrations and their correlations with analgesia in patients with cancer pain...
  13. doi request reprint The role of methadone in opioid rotation-a Polish experience
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, Poznan 61 245, Poland
    Support Care Cancer 17:607-12. 2009
    ..To assess methadone analgesia, adverse effects, and calculation method of equianalgesic doses with oral morphine...
  14. doi request reprint The role of methadone in cancer pain treatment--a review
    W Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Int J Clin Pract 63:1095-109. 2009
    ..Methadone is an opioid analgesic of step 3 of the World Health Organization (WHO) analgesic ladder...
  15. ncbi request reprint Tramadol as an analgesic for mild to moderate cancer pain
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
    Pharmacol Rep 61:978-92. 2009
    ....
  16. ncbi request reprint Dihydrocodeine as an opioid analgesic for the treatment of moderate to severe chronic pain
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
    Curr Drug Metab 11:494-506. 2010
    ..The impact of CYP2D6 activity on DHC analgesia was discussed and a proposal of calculation equianalgesic doses of DHC to other opioids was put forward...
  17. doi request reprint Polish brief pain inventory for pain assessment and monitoring of pain treatment in patients with cancer
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    J Palliat Med 13:663-8. 2010
    ..To adapt the Brief Pain Inventory-Short Form (BPI-SF) to Polish and to evaluate its psychometric properties (validity and reliability) in patients with cancer pain and to use BPI-SF for pain assessment and monitoring of pain treatment...
  18. doi request reprint The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poland
    Adv Ther 27:714-30. 2010
    ..On the other hand, uncontrolled OIC and the necessity to perform rectal invasive procedures (enema, manual evacuation) lead not only to increased health care costs, but most importantly, cause severe patient suffering...
  19. ncbi request reprint Role of oxycodone and oxycodone/naloxone in cancer pain management
    Wojciech Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, PL 61 245 Poznań, Poland
    Pharmacol Rep 62:578-91. 2010
    ..The potential role of oxycodone/naloxone in chronic pain management and its impact on the bowel function is also discussed...
  20. doi request reprint The impact of tramadol and dihydrocodeine treatment on quality of life of patients with cancer pain
    W Leppert
    Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
    Int J Clin Pract 64:1681-7. 2010
    ..The aim of the study was to assess the impact of tramadol and DHC treatment on quality of life (QL) and performance status (PS) of patients with cancer pain...
  21. ncbi request reprint The role of tramadol in cancer pain treatment--a review
    Wojciech Leppert
    Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Osiedle Rusa 25 A, 61 245, Poznan, Poland
    Support Care Cancer 13:5-17. 2005
    ..In this article we summarize data on pharmacology, mechanisms of action, pharmacokinetics, side effects and clinical experience assessing analgesic efficacy, adverse reactions and safety of tramadol in cancer pain...