Affiliation: Medical University of Silesia
Jaworska D, KrÃ³l W, Szliszka E. Prostate Cancer Stem Cells: Research Advances. Int J Mol Sci. 2015;16:27433-49 pubmed publisher
..Eradicating prostate cancer stem cells, the root of the problem, has been considered as a promising target in prostate cancer treatment to improve the prognosis for patients with advanced stages of the disease. ..
Kłósek M, Mertas A, Krol W, Jaworska D, Szymszal J, Szliszka E. Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Prostate Cancer Cells after Treatment with Xanthohumol-A Natural Compound Present in Humulus lupulus L. Int J Mol Sci. 2016;17: pubmed publisher
..The findings suggest that xanthohumol is a compound of potential use in chemoprevention of prostate cancer due to its sensitization of cancer cells to TRAIL-mediated apoptosis. ..
Bronikowska J, Szliszka E, Kostrzewa Susłow E, Jaworska D, Czuba Z, Bednarski P, et al
. Novel Structurally Related Flavones Augment Cell Death Induced by rhsTRAIL. Int J Mol Sci. 2017;18: pubmed publisher
..8 ± 1.7%-91.4 ± 1.7%; apoptosis increase of 33.0 ± 0.7%-78.5 ± 0.9%). Our study demonstrates the potential use of tested flavones in TRAIL-based anticancer therapy and prevention. ..
Jaworska D, Szliszka E. Targeting Apoptotic Activity Against Prostate Cancer Stem Cells. Int J Mol Sci. 2017;18: pubmed publisher
..The results of our study show that treatment with paclitaxel, cabazitaxel and docetaxel is able to enhance the apoptosis induced by TRAIL even in prostate cancer stem cells. ..