F Burdan

Summary

Affiliation: Medical University
Country: Poland

Publications

  1. ncbi request reprint Effect of iodothyronine hormone status on doxorubicin related cardiotoxicity
    J Dudka
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin
    Folia Morphol (Warsz) 72:340-8. 2013
  2. pmc Incidence of spinal perineurial (Tarlov) cysts among East-European patients
    Franciszek Burdan
    Department of Radiology, St John s Cancer Center, Lublin, Poland
    PLoS ONE 8:e71514. 2013
  3. ncbi request reprint Morphology of the foramen magnum in young Eastern European adults
    F Burdan
    Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 71:205-16. 2012
  4. ncbi request reprint Anatomical classification of the shape and topography of the operated stomach
    F Burdan
    Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 71:129-35. 2012
  5. ncbi request reprint [Developmental toxicity of the over-the-counter analgetics and antypiretics]
    Franciszek Burdan
    Department of Human Anatomy, Medical University of Lublin, Poland
    Pol Merkur Lekarski 32:410-3. 2012
  6. ncbi request reprint Prenatal tolerability of acetaminophen and other over-the-counter non-selective cyclooxygenase inhibitors
    Franciszek Burdan
    Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4, PL 20 090 Lublin, Poland
    Pharmacol Rep 64:521-7. 2012
  7. ncbi request reprint Anatomical variances and dimensions of the superior orbital fissure and foramen ovale in adults
    F Burdan
    Department of Human Anatomy, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 70:263-71. 2011
  8. pmc Anatomical classification of the shape and topography of the stomach
    Franciszek Burdan
    Human Anatomy Department, Medical University of Lublin, 4 Jaczewskiego Str, 20 090, Lublin, Poland
    Surg Radiol Anat 34:171-8. 2012
  9. ncbi request reprint Celosomy is associated with prenatal exposure to cyclooxygenase inhibitors
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, 4 Jaczewskiego Str, PL 20090 Lublin, Poland
    Pharmacol Res 53:287-92. 2006
  10. ncbi request reprint [Development and congenital malformations of the skeleton]
    Franciszek Burdan
    Pracownia Teratologii Doświadczalnej Katedry i Zakładu Anatomii Prawidłowej Człowieka Akademii Medycznej im prof Feliksa Skubiszewskiego w Lublinie
    Pol Merkur Lekarski 19:94-7. 2005

Collaborators

Detail Information

Publications76

  1. ncbi request reprint Effect of iodothyronine hormone status on doxorubicin related cardiotoxicity
    J Dudka
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin
    Folia Morphol (Warsz) 72:340-8. 2013
    ..Hypothyreosis had no effect on heart stretching and on necrosis at morphological level, but caused biochemical symptoms of cardiomyocyte necrosis in rats receiving doxorubicin. ..
  2. pmc Incidence of spinal perineurial (Tarlov) cysts among East-European patients
    Franciszek Burdan
    Department of Radiology, St John s Cancer Center, Lublin, Poland
    PLoS ONE 8:e71514. 2013
    ..Insignificant changes were seen for patient age and cyst size. Perineurial spinal cysts were the most frequently observed on the sacral level and such changes were more common in females. ..
  3. ncbi request reprint Morphology of the foramen magnum in young Eastern European adults
    F Burdan
    Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 71:205-16. 2012
    ..The aim of the study was to evaluate the morphology of the foramen magnum in adult individuals in relation to sex...
  4. ncbi request reprint Anatomical classification of the shape and topography of the operated stomach
    F Burdan
    Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 71:129-35. 2012
    ..In banding, the body of the stomach forms an hourglass at the level of the artificial adjustable band, typically applied in surgical treatment of obesity (slim surgery)...
  5. ncbi request reprint [Developmental toxicity of the over-the-counter analgetics and antypiretics]
    Franciszek Burdan
    Department of Human Anatomy, Medical University of Lublin, Poland
    Pol Merkur Lekarski 32:410-3. 2012
    ..Furthermore, epidemiological data suggest higher risk of cardiac, abdominal wall and orofacial defects of evaluated drugs...
  6. ncbi request reprint Prenatal tolerability of acetaminophen and other over-the-counter non-selective cyclooxygenase inhibitors
    Franciszek Burdan
    Department of Human Anatomy, Medical University of Lublin, Jaczewskiego 4, PL 20 090 Lublin, Poland
    Pharmacol Rep 64:521-7. 2012
    ....
  7. ncbi request reprint Anatomical variances and dimensions of the superior orbital fissure and foramen ovale in adults
    F Burdan
    Department of Human Anatomy, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 70:263-71. 2011
    ..The diameters of both superior orbital fissures and ovale foramina indicated the asymmetry of the neurocranium...
  8. pmc Anatomical classification of the shape and topography of the stomach
    Franciszek Burdan
    Human Anatomy Department, Medical University of Lublin, 4 Jaczewskiego Str, 20 090, Lublin, Poland
    Surg Radiol Anat 34:171-8. 2012
    ..The third and fourth groups comprise developmental variations and organ malformations that were not observed in evaluated patients. The last group (V) encloses mixed forms that connect two or more previous variations...
  9. ncbi request reprint Celosomy is associated with prenatal exposure to cyclooxygenase inhibitors
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, 4 Jaczewskiego Str, PL 20090 Lublin, Poland
    Pharmacol Res 53:287-92. 2006
    ..It could be stressed that aspirin, unlike other non-selective and selective COX-2 inhibitors increases the risk of the abdominal wall defects, which are observed more often in growth-retarded fetuses...
  10. ncbi request reprint [Development and congenital malformations of the skeleton]
    Franciszek Burdan
    Pracownia Teratologii Doświadczalnej Katedry i Zakładu Anatomii Prawidłowej Człowieka Akademii Medycznej im prof Feliksa Skubiszewskiego w Lublinie
    Pol Merkur Lekarski 19:94-7. 2005
    ..Development of fibrous, cartilaginous and synovial joints, bone maturation and remodeling, and mechanisms leading to skeleton dysmorphogenesis are also discussed...
  11. ncbi request reprint Skeletal developmental effects of selective and nonselective cyclooxygenase-2 inhibitors administered through organogenesis and fetogenesis in Wistar CRL:(WI)WUBR rats
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy, Lublin, Poland
    Toxicology 216:204-23. 2005
    ....
  12. ncbi request reprint [The effect of cyclooxygenase inhibitors on the bone and cartilage]
    Franciszek Burdan
    Zakładu Anatomii Prawidłowej Człowieka AM w Lublinie
    Pol Merkur Lekarski 18:709-11. 2005
    ..In case of in-utero exposure non-selective drugs may induce skeletal developmental variations, which depends on the used dose and COX-1 inhibition potency...
  13. ncbi request reprint [Maple syrup vs. congenital anomaly...--Report from 44th Annual Meeting of the Teratology Society--Vancouver, Canada]
    Franciszek Burdan
    Pracownia Teratologii Doświadczalnej działajaca przy Katedrze i Zakładzie Anatomii Prawidłowej Człowieka AM, Lublinie
    Ginekol Pol 76:337-8. 2005
  14. ncbi request reprint Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, 1 Raclawickie Ave, Medical University of Lublin, PL 20950 Lublin, Poland
    Toxicology 211:12-25. 2005
    ..The aim of the experiment was to evaluate the developmental toxicity of the non-selective (piroxicam) and selective (DFU; 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanon) COX-2 inhibitors...
  15. ncbi request reprint Morphological studies in modern teratological investigations
    Franciszek Burdan
    Experimental Teratology Unit, Department of Human Anatomy, Medical University of Lublin, 20 074 Lublin, Poland
    Folia Morphol (Warsz) 64:1-8. 2005
    ..A single alizarin red S and double alcian blue followed by alizarin red S staining, as well as various methods of soft tissue examination are discussed...
  16. ncbi request reprint Immunoexpression of constitutive and inducible cyclooxygenase isoforms in distinguishing and accessory structures of synovial joints in rat foetuses
    F Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Poland
    Folia Morphol (Warsz) 68:59-64. 2009
    ..It could be concluded that both constitutive and inducible COX isoforms are physiologically expressed in various structures of synovial joints in rat foetuses at the end of prenatal development...
  17. ncbi request reprint [How should pregnant women be informed about drug toxicity? Report from the 43rd annual meeting of the Teratology Society--June 21-26. 2003--Philadelphia, USA]
    Franciszek Burdan
    Zakład Anatomii Prawidłowej Człowieka Akademii Medycznej w Lublinie
    Pol Merkur Lekarski 17:667-8. 2004
    ..This report refers actual opinions of drug risk assessment and pregnancy labeling presented during the 43rd Annual Meeting of Teratology Society. The other congress topics are also reviewed...
  18. ncbi request reprint [Cyclooxygenase and prostanoids--biological implications]
    Franciszek Burdan
    Pracownia Teratologii Doświadczalnej Zakładu Anatomii Prawidłowej Człowieka Akademii Medycznej im Prof Feliksa Skubiszewskiego w Lublinie
    Postepy Hig Med Dosw (Online) 60:129-41. 2006
    ..It increases in inflammatory, degenerative, and neoplastic processes...
  19. ncbi request reprint The activity and immunoexpression of cathepsin D in rat male reproductive organs
    F Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Morphol (Warsz) 65:111-5. 2006
    ..Although there were differences in enzyme activity between various organs of the male reproductive system, cathepsin D immunoreactivity was seen exclusively in the Sertoli and Leydig cells in the testis...
  20. ncbi request reprint [Wilson's principles--a base of modern teratology]
    Franciszek Burdan
    Akademia Medyczna w Lublinie, Pracownia Teratologii Doświadczalnej Katedry i Zakładu Anatomii Prawidłowej Człowieka
    Pol Merkur Lekarski 20:358-61. 2006
    ..Manifestations of deviant development depends on the dosage and exposure frequency. In case of abnormal development the final manifestations include death of embryo or fetus, malformation, growth retardation and functional disorder...
  21. doi request reprint Unusual interleukin-1 and -6 expression in fetal cartilage is associated with placental abnormalities
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Histochem Cytobiol 48:30-6. 2010
    ..It could be concluded that abnormal expression of the selected interleukins is associated with low placental weight and decrease of its thickness, especially labyrinth zone, as well as with high maternal urea level...
  22. doi request reprint Morphology and physiology of the epiphyseal growth plate
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Folia Histochem Cytobiol 47:5-16. 2009
    ..Any disturbances of the epiphyseal development and its physiology result in various skeletal abnormalities known as dysplasia...
  23. doi request reprint Maternal toxicity of nonsteroidal anti-inflammatory drugs as an important factor affecting prenatal development
    Franciszek Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, 4 Jaczewskiego Str, PL 20 090 Lublin, Poland
    Reprod Toxicol 28:239-44. 2009
    ..On the other hand, decrease in fetal length has been the only sign of toxicity found after exposure to selective COX-2 inhibitor (DFU). The aim of the study was to evaluate maternal effects on selected developmental abnormalities...
  24. ncbi request reprint Immunoexpression of constitutive and inducible cyclo-oxygenase isoforms in the rat foetal and maternal digestive tract
    F Burdan
    Experimental Teratology Unit of the Department of Human Anatomy, Medical University, Lublin, Poland
    Folia Morphol (Warsz) 67:24-31. 2008
    ..In conclusion, constitutive and inducible COX isoforms were detected in the digestive tract of pregnant female and in foetuses. COX-1 was the predominant isoform in both the adult and foetal organs...
  25. ncbi request reprint [Developmental toxicity of naproxen]
    Franciszek Burdan
    Akademia Medyczna w Lublinie, Pracownia Teratologii Doświadczalnej Katedry i Zakładu Anatomii Prawidłowej Człowieka
    Pol Merkur Lekarski 23:155-8. 2007
    ..It may also induce lip and/or palate clefts and cardiac malformations, especially the ventricular septal defect...
  26. ncbi request reprint Cyclooxygenase inhibitors affect bone mineralization in rat fetuses
    Franciszek Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Cells Tissues Organs 187:221-32. 2008
    ..It should be stressed that unlike DFU, the examined nonselective COX inhibitors decreased fetal bone mineralization when administered in high maternal toxic doses. Moreover, maternal health status determined fetal bone mineralization...
  27. ncbi request reprint Association of maternal pancreatic function and foetal growth in rats treated with DFU, a selective cyclooxygenase-2 inhibitor
    F Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Poland
    Folia Morphol (Warsz) 66:172-80. 2007
    ..It should be stressed that DFU administered throughout mid and late pregnancy in rats did not change maternal or foetal pancreatic morphology or immunoexpression of either of the main COX isoforms in the organ...
  28. ncbi request reprint Congenital ventricular septal defects and prenatal exposure to cyclooxygenase inhibitors
    F Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, Poland
    Braz J Med Biol Res 39:925-34. 2006
    ..We conclude that prenatal exposure to COX inhibitors, especially aspirin and ibuprofen, increased the incidence of VSDs in rat offspring but was not related to fetal growth retardation...
  29. ncbi request reprint Developmental toxicity evaluation of ibuprofen and tolmetin administered in triple daily doses to Wistar CRL:(WI)WUBR rats
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, Lublin, Poland
    Birth Defects Res B Dev Reprod Toxicol 71:321-30. 2004
    ..However, since both cyclooxygenase (COX) inhibitors have a short half-life, the current report presents drug developmental effects after triple daily doses administration, as they are used in human...
  30. ncbi request reprint Gastrointestinal and hepatic toxicity of selective and non-selective cyclooxygenase-2 inhibitors in pregnant and non-pregnant rats
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, 1 Spokojna Str, PL 20074 Lublin, Poland
    Pharmacol Res 50:533-43. 2004
    ..Tolerability of non-selective COX inhibitors was lower in both pregnant and non-pregnant groups when compared with DFU. Insignificant mortality and histological changes were noted between pregnant and non-pregnant groups...
  31. ncbi request reprint [Coxibs: highly selective cyclooxygenase-2 inhibitors. Part I. Clinical efficacy]
    Franciszek Burdan
    Pracownia Teratologii Doświadczalnej, Katedrze i Zakładzie Anatomii Prawidłowej Człowieka Akademii Medycznej w Lublinie
    Pol Merkur Lekarski 14:348-51. 2003
    ..The physiology and pathophysiology of both COX isoforms (COX-1, COX-2) are also discussed...
  32. ncbi request reprint Intrauterine growth retardation and lack of teratogenic effects of prenatal exposure to the combination of paracetamol and caffeine in Wistar rats
    Franciszek Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, 1 Spokojna Str, PL 20074 Lublin, Poland
    Reprod Toxicol 17:51-8. 2003
    ..Dose-dependent effects in the middle and high dose groups on fetal body weight/growth and placental weight were found. In none of the three dose groups was there an increase in external or internal congenital malformations...
  33. ncbi request reprint [Coxibs: highly selective cyclooxygenase-2 inhibitors. Part II. Side effects]
    Franciszek Burdan
    Pracownia Teratologii Doświadczalnej, Katedrze i Zakładzie Anatomii Prawidłowej Człowieka, Akademii Medycznej w Lublinie
    Pol Merkur Lekarski 14:352-5. 2003
    ..Pregnancy and lactation require precise monitoring of adverse effects on the fetus, neonate and infant, or discontinuation of therapy with the drug...
  34. ncbi request reprint A new rapid radiological procedure for routine teratological use in bone ossification assessment: a supplement for staining methods
    Franciszek Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, PL 20074 Lublin, Poland
    Teratology 66:315-25. 2002
    ..Here we introduce a simple new method that allows quantitative determination of skeleton ossification before routine staining examination...
  35. ncbi request reprint Formation of the knee joint after prenatal propyphenazone (isopropylantipyrine) administration
    Franciszek Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, Poland
    Cells Tissues Organs 171:145-51. 2002
    ..66%) and in one fetus from group R2 (1.63%). No histological changes were observed. Based on obtained results, it could be concluded that propyphenazone did not delay the formation of the knee joint...
  36. ncbi request reprint Effects of prenatal exposure to combination of acetaminophen, isopropylantipyrine and caffeine on intrauterine development in rats
    F Burdan
    Human Anatomy Department, Medical University of Lublin, Poland
    Hum Exp Toxicol 21:25-31. 2002
    ..The number of corpora lutea, fetuses, resorptions, preimplantation and postimplantation mortality did not exhibit any significant difference. Nonsignificant incidence of fetal anomalies was found...
  37. ncbi request reprint Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol
    F Burdan
    Experimental Teratology Unit of the Human Anatomy Department, Medical University of Lublin, PL 20074 Lublin, Poland
    Hum Exp Toxicol 23:235-44. 2004
    ..The risk of midline defects (umbilical hernia and gastroschisis) is discussed...
  38. ncbi request reprint Prenatal effects of DuP-697-the irreversible, highly selective cyclooxygenase-2 inhibitor
    Franciszek Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, PL 20074 Lublin, Poland
    Reprod Toxicol 17:413-9. 2003
    ..These changes were not increased (P<0.1) in the middle drug-dose group. The experimentally-derived NOAEL for developmental toxicity was 0.05 mg/kg, and the corresponding LOAEL was 3.5 mg/kg...
  39. doi request reprint Developmental outcome after exposure to cyclooxygenase inhibitors during pregnancy and lactation
    Franciszek Burdan
    Department of Human Anatomy, Medical University of Lublin, 4 Jaczewskiego Str, Lublin, Poland
    Reprod Toxicol 32:407-17. 2011
    ..Non-selective cyclooxygenase inhibitors (non-steroidal anti-inflammatory drugs--NSAID) affected pups growth and influenced mineralization of the lumbar vertebrae...
  40. ncbi request reprint Combined effects of acetaminophen, isopropylantipyrine and caffeine on pregnant and nonpregnant liver
    F Burdan
    Human Anatomy Department, Medical University of Lublin, Poland
    Hum Exp Toxicol 20:569-75. 2001
    ..The treatment resulted in minimal reactive and degenerative changes in light microscopic pattern of liver...
  41. ncbi request reprint Effect of selected alcohol dehydrogenase inhibitors on the human heart lactate dehydrogenase activity--an in vitro study
    J Dudka
    Department of Clinical Pathomorphology, Medical University of Lublin, Poland
    Acta Physiol Hung 91:235-41. 2004
    ..Thus, 4-MP was found to be the most effective inhibitor of LDH of all compounds tested. Therefore, such effect of 4-MP seems to be an additional advantage in methanol and ethylene glycol intoxications...
  42. ncbi request reprint The effects of short-time caffeine administration on skeleton development in Wistar rats
    F Burdan
    Experimental Teratology Unit of Human Anatomy Department, Medical University School, Lublin, Poland
    Folia Morphol (Warsz) 59:91-5. 2000
    ..The skeletons were stained with alizarin red-S. The examination showed an insignificant (P < 0.05) number of skeleton malformations, external haematomas and any internal malformations...
  43. ncbi request reprint Changes in pancreatic lysosomal enzymes activity as the potential factors leading to diabetic enteropathy
    R Maciejewski
    Department of Human Anatomy, Medical University of Lublin, Poland
    J Physiol Pharmacol 52:823-34. 2001
    ....
  44. ncbi request reprint Temporary elevation of pancreatic lysosomal enzymes, as a result of the omeprazole-induced peripancreatic inflammation in male Wistar rats
    F Burdan
    Human Anatomy Department, Medical University School of Lubin, Poland
    J Physiol Pharmacol 51:463-70. 2000
    ..We concluded that intraperitoneal administration of omeprazole causes tissue inflammation in the peripancreatic lipid tissue and reactive elevation of some pancreatic lysosomal enzymes...
  45. ncbi request reprint Evaluation of bone formation in fetal skeletons following prenatal paracetamol administration in single alizarin-stained specimens in Wistar rats
    F Burdan
    Human Anatomy Department, Medical University School of Lublin, Poland
    Folia Morphol (Warsz) 59:167-71. 2000
    ..5 mg/kg, P2--35.0 mg/kg, P3--350.0 mg/kg. The foetuses were delivered by laparotomy on the 21st day of pregnancy and fixed in alcohol. The skeletons were stained with alizarin. Insignificant differences of bone malformations were found...
  46. ncbi request reprint Somatic and skeleton development of rat foetuses following in-utero exposure to isopropylantipyrine (propyphenazone) during the second trimester of gestation
    F Burdan
    Human Anatomy Department, Medical University School of Lublin, Poland
    Folia Morphol (Warsz) 59:317-22. 2000
    ..External and skeletal examination of the foetuses revealed no evidence of teratogenesis. It can be concluded that IPA has no harmful effects on the prenatal development of the rat offspring at doses used in the present study...
  47. ncbi request reprint Activity of cathepsin B, D and L in rat cerebrum after cimetidine and famotidine administration
    F Burdan
    Experimental Teratology Unit, Medical University of Lublin, Lublin, Poland
    Acta Physiol Hung 90:115-23. 2003
    ..Cathepsin activities were normalized during the next six weeks. No behavioural changes were noted among the observed animals. Unlike cimetidine, famotidine did not change profiles of the cerebral cathepsins...
  48. ncbi request reprint Biochemical and immunohistochemical study on physiological activity and distribution of hepatic cathepsin D
    F Burdan
    Experimental Teratology Unit, Human Anatomy Department, Medical University of Lublin, Poland
    Acta Physiol Hung 90:47-56. 2003
    ..The rat Browicz-Kupffer cells revealed the highest activity of cathepsin D...
  49. ncbi request reprint Selected biochemical parameters and ultrastructural picture of pancreas due to Ulinastatin treatment of experimental acute pancreatitis
    R Maciejewski
    Human Anatomy Department, Medical University of Lublin, PL 20074 Lublin, Poland
    Exp Toxicol Pathol 56:305-11. 2005
    ..However, in the UTI-treated subjects, pathological processes proceeded with the significantly slower pace and in much smaller quantities...
  50. ncbi request reprint [Prenatal tolerability evaluation of diclofenac]
    Piotr Przybylski
    Akademia Medyczna w Lublinie, Pracownia Teratologii Doświadczalnej Katedry i Zakładu Anatomii Prawidłowej Człowieka
    Pol Merkur Lekarski 22:229-32. 2007
    ..On the other hand, data from human reports do not support opinion about the connection between diclofenac exposure and the potential risk to the fetus...
  51. ncbi request reprint Lipid and exocrine pancreatic ultrastructural changes due to experimental diabetes
    R Maciejewski
    Department of Human Anatomy, Medical University of Lublin, Poland
    Acta Physiol Hung 88:63-72. 2001
    ..We concluded that the intensification of ultrastructural changes of the exocrine part of the pancreas correlated with the changes of the pancreatic lipase activity, and glucose and lipoprotein levels...
  52. ncbi request reprint Visualisation of diverticula of the upper part of the alimentary tract; comparison of roentgenologic and endoscopic techniques
    F Burdan
    Department of Human Anatomy, 2nd Department of Radiology, Medical University of Lublin, Poland
    Folia Morphol (Warsz) 60:297-301. 2001
    ..Both diagnostic procedures are usually supplemented by manometric examination of the oesophagus and superior and inferior oesophageal sphincters. This enables the accurate diverticula etiology to be stated...
  53. ncbi request reprint Intrapancreatic accessory spleen
    J Szumiło
    Department of Clinical Pathomorphology, Medical University of Lublin, Poland
    Folia Morphol (Warsz) 71:45-7. 2012
    ..Since a lack of morphological features of trisomy 13 syndrome were found in the foetus, the ectopic spleens were regarded as incidental findings...
  54. ncbi request reprint Sebaceous glands - unusual histological finding in the uterine cervix
    J Szumiło
    Department of Clinical Pathomorphology, Medical University of Lublin, Jaczewskiego 8, 20 059 Lubin, Poland
    Folia Morphol (Warsz) 68:287-9. 2009
    ..It could be concluded that sebaceous glands in the ectocervix are rare lesions of unclear origin and low clinical significance. However, the glands could potentially be associated with sebaceous carcinoma of that anatomical site...
  55. ncbi request reprint [Objects and evolution courses of modern teratology. Report from the 41st Annual Meeting of the Teratology Society--June 23-28.06.2001--Montreal. Canada]
    F Burdan
    Pracownia Teratologii Doświadczalnej, Katedrze i Zakładzie Anatomii Prawidłowej Człowieka Akademii Medycznej w Lublinie
    Pol Merkur Lekarski 11:543-4. 2001
    ..This report refers to the actual opinions on epidemiology, pathogenesis and prevention of congenital malformations presented during the 41st Annual Meeting of Teratology Society, held on the 23rd-28th June 2001 at Montreal in Canada...
  56. ncbi request reprint [Genetic base of esophageal squamous cell carcinoma susceptibility]
    Justyna Szumiło
    Medical University of Lublin, Poland
    Pol Merkur Lekarski 26:93-7. 2009
    ..Introduction of genetic screening test allows effective, purpose-oriented methods of prevention and in patients suffered from the cancer--application of optimal therapy and minimization of side-effects...
  57. ncbi request reprint Activity of NADPH-cytochrome P-450 reductase of the human heart, liver and lungs in the presence of (-)-epigallocatechin gallate, quercetin and resveratrol: an in vitro study
    Jaroslaw Dudka
    Department of Clinical Pathomorphology, Medical University of Lublin, 8 Jaczewskiego Str, PL 20093 Lublin, Poland
    Basic Clin Pharmacol Toxicol 97:74-9. 2005
    ..A beneficial effect may be obtained in anticancer therapy with bioreductive agents like tirapazamine...
  58. ncbi request reprint Effect of selected alcohol dehydrogenase inhibitors on human hepatic lactate dehydrogenase activity - an in vitro study
    Jaroslaw Dudka
    Department of Clinical Pathomorphology, Medical University of Lublin, PL 20 950 Lublin, Poland
    J Appl Toxicol 25:549-53. 2005
    ..On the other hand, the decrease of LDH activity in the presence of Ukrain is a promising finding but definitely requires further investigation...
  59. ncbi request reprint Human skeletal muscle lactate dehydrogenase activity in the presence of some alcohol dehydrogenase inhibitors
    Jaroslaw Dudka
    Department of Clinical Pathomorphology, Medical University of Lublin, 8 Jaczewskiego Str, PL 20 090, Poland
    Basic Clin Pharmacol Toxicol 95:38-42. 2004
    ..1 mM and higher concentration. By contrast, no significant effect on lactate dehydrogenase activity in the presence of ethylenediaminetetraacetic acid disodium salt, methanol and ethanol was observed...
  60. doi request reprint Expression of syndecan-1 and cathepsins D and K in advanced esophageal squamous cell carcinoma
    Justyna Szumilo
    Department of Clinical Pathomorphology, Medical University of Lublin, Lublin, Poland
    Folia Histochem Cytobiol 47:571-8. 2009
    ..The results may suggest a relationship between syndecan-1 and cathepsins D and K with growth and invasiveness of esophageal squamous cell carcinoma, but such thesis requires further study on a larger and more heterogeneous population...
  61. ncbi request reprint [Cyclooxygenase inhibitors in chemoprevention and treatment of esophageal squamous cell carcinoma]
    Justyna Szumiło
    Department of Clinical Pathomorphology, Medical University of Lublin, Poland
    Pol Merkur Lekarski 27:408-12. 2009
    ..Few reports concerning application of selective COX-2 inhibitors in patients with invasive squamous cell carcinoma are insufficient for ultimate evaluation of this method of therapy...
  62. ncbi request reprint [Human erythrocyte lactate dehydrogenase activity changes in the presence of some alcohol dehydrogenase inhibitors]
    Jarosław Dudka
    Katedra i Zakład Patomorfologii Klinicznej AM w Lublinie, 20 950 Lublin, ul Jaczewskiego 8
    Rocz Panstw Zakl Hig 55:229-34. 2004
    ..10 mM (p < 0.05) and 1.0 mM (p < 0.01) of cimetidine and EDTA. There were no observed any significant changes vs. control in LDH activity when 4MP, ethanol or methanol was added to environment of reaction...
  63. ncbi request reprint [The diagnosis of anthracycline-induced cardiac damage and heart failure]
    Jarosław Dudka
    Katedra i Zakład Patomorfologii Klinicznej, UM w Lublinie, 20 950 Lublin
    Postepy Hig Med Dosw (Online) 63:225-33. 2009
    ..However, the clinical use of biochemical parameters in diagnosing anthracycline-related cardiotoxicity is still a controversial issue...
  64. ncbi request reprint Visualisation of diverticula of the upper part of the alimentary tract; comparison of roentgenologic and endoscopic techniques
    Franciszek Burdan
    Department of Human Anatomy, Medical University of Lublin, ul Spokojna 1, 20 074 Lublin, Poland
    Folia Morphol (Warsz) 61:297-301. 2002
    ..Both diagnostic procedures are usually supplemented by manometric examination of the oesophagus and superior and inferior oesophageal sphincters. This enables the accurate diverticula etiology to be stated...
  65. doi request reprint Cancer of the accessory breast--a case report
    B Madej
    Department of General Surgery and Sub department of Surgical Oncology, Cardinal Rev Wyszyński s Voivodship Specialistic Hospital, Lublin, Poland
    Adv Med Sci 54:308-10. 2009
    ..Preventive resection of accessory breast in women at high risk of developing breast cancer can be considered as the treatment of choice in most patients...
  66. ncbi request reprint [Prenatal effects of acetylsalicylic acid]
    F Burdan
    Pracownia Teratologii Doświadczalnej, Katedrze i Zakładzie Anatomii Prawidłowej Człowieka Akademii Medycznej w Lublinie
    Pol Merkur Lekarski 11:182-6. 2001
    ..Anti-inflammatory doses should be stopped in the third trimester of gestation or given if the drug is needed in life-threatening situation or for serious disease for which safer drugs can not be used or are ineffective...
  67. ncbi request reprint Blue nevus of the endocervix
    J Szumiło
    Department of Clinical Pathomorphology, Medical University of Lublin, Poland
    Folia Morphol (Warsz) 69:62-4. 2010
    ..Although the blue nevi seem to be lesions of low clinical significance, they require careful differential diagnosis with malignant melanoma, especially in scanty endocervical curettage or cervical biopsy specimens...
  68. ncbi request reprint Breast cancer--the diagnostic and therapeutic problem
    B Madej
    Department of Human Anatomy, Medical University of Lublin
    Ann Univ Mariae Curie Sklodowska Med 56:221-4. 2001
    ..98% of cases, in 42.2% adenofibroma, in 2.31% papilloma mammae, in 1.73% mastitis chronica, in 4.62% ca ductale invasivum and in 1.16% ca ductale in situ has been observed...
  69. ncbi request reprint Hepatic lysosomal enzymes activity and liver morphology after short-time omeprazole administration
    Franciszek Burdan
    Human Anatomy Department, Medical University of Lublin, Poland
    Exp Toxicol Pathol 53:453-9. 2002
    ..It could be concluded that observed differences of hepatic lysosomal enzyme activities were the result of accompanied chemical-induced peritonitis as previously reported, and not a direct drug-toxic effect...
  70. ncbi request reprint Solid-pseudopapillary neoplasm of the pancreas - comparisons between magnetic resonance and histological findings
    Franciszek Burdan
    Prof Justyna Szumiło MD, PhD, Department of Clinical Pathomorphology, Medical University of Lublin, Jaczewskiego 8, 20 059 Lublin, Poland, tel 48 81 718 73 25, fax 48 81 718 73 24, E mail
    Pol J Pathol 64:216-23. 2013
    ..Histological appearance of the solid-pseudopapillary neoplasm corresponded with its radiological morphology. ..
  71. ncbi request reprint Morphology of root canals in adult premolar teeth
    T K Rózyło
    Department of Dental and Maxillofacial Radiology, Medical University of Lublin, Poland
    Folia Morphol (Warsz) 67:280-5. 2008
    ..7% of these teeth had two root canals. Most of the second lower premolars (68.2%) had a single root canal, while the remaining 31.8% had two root canals. None of the mandibular premolars examined had three root canals...
  72. ncbi request reprint Level of malondialdehyde after short-time omeprazole administration
    F Burdan
    Experimental Teratology Unit, Department of Human Anatomy, Medical University, ul Spokojna 1, 20 074 Lublin, Poland
    Med Sci Monit 7:89-92. 2001
    ..The purpose of the study was to evaluate the effect of omeprazole (O) on the level of plasma malondialdehyde (MDA)...
  73. ncbi request reprint Blockade of reticular formation activity, due to carisoprodol maternal administration, and its effects on rat skeleton development
    Tomasz Blicharski
    Experimental Teratology Unit of Human Anatomy Department, Medical University of Lublin
    Ann Univ Mariae Curie Sklodowska Med 57:143-9. 2002
    ..Insignificant number of subcutaneous ecchymose and various skeleton anomalies were observed. The experiment revealed that carisoprodol has no influence on rat skeleton development...
  74. ncbi request reprint Non-steroidal anti-inflammatory drugs are not fully safe for fetus: comments on the article Treating common ear problems in pregnancy: what is safe? by Vlastarakos et al
    Franciszek Burdan
    Eur Arch Otorhinolaryngol 265:609-11. 2008
  75. ncbi request reprint Optimization of analysis of skeletal ossification of laboratory animals by means of digital radiography software options
    Ingrid Różyło-Kalinowska
    2nd Department of Radiology, Medical University of Lublin
    Ann Univ Mariae Curie Sklodowska Med 58:95-100. 2003
    ..Digital radiography is a novel and precise tool in determination of skeleton ossification and could be used as a supplement to routine staining methods...
  76. ncbi request reprint [Folic acid isn't sufficient for prevention of congenital defects. Report from the 42nd Teratologic Society Conference--6/22-27, 2002--Scottsdale Az, USA]
    Franciszek Burdan
    Ginekol Pol 73:1247-9. 2002