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Genomes and Genes
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Publications
The impact of a quadrivalent human papillomavirus (types 6, 11, 16, 18) virus-like particle vaccine in European women aged 16 to 24S Majewski
Department of Dermatology and Venereology, Center of Diagnostics and Treatment of Sexually Transmitted Diseases, Medical University of Warsaw, Warsaw, Poland
J Eur Acad Dermatol Venereol 23:1147-55. 2009..Herein, we evaluated the impact of the quadrivalent HPV 6/11/16/18 L1 VLP vaccine on prevention of HPV-associated cervico-genital lesions in a broad population of sexually active European women...
3D ultrasound examination of the superficial lymph nodes--does it provide additional information?E J Bialek
Department of Diagnostic Imaging, Second Faculty of Medicine, Medical University of Warsaw, Poland
Ultraschall Med 27:467-72. 2006..To compare the appearance of superficial lymph nodes on standard two-dimensional (2D) ultrasound examination and on three-dimensional (3D) ultrasound examination...
Extensive mixed vascular malformation clinically imitating multiple sclerosis--case reportJ Rafalowska
Department of Experimental and Clinical Neuropathology, Medical Research Centre, Polish Academy of Sciences, Pawinskiego str 5, 02 106 Warsaw, Poland
Clin Neuropathol 25:237-42. 2006..The presence of various types of pathological vessels originating from different ontogenic periods indicates remittent or prolonged influence of teratogenic factor(s) in all periods of fetal vessel development...
[Transient hyponatremia the first symptome of multiple endocrine neoplasia type 1 (MEN 1)--case report]Marek Czarkowski
Katedra i Klinika Chorób Wewnetrznych i Endokrynologii AM, Warszawie
Pol Arch Med Wewn 114:768-72. 2005..was diagnosed in the old age while the majority of MEN 1 patients are younger, 3. asymptomatic course of hypercalcemia indicates that in some of elder patients removal of the parathyroid glands might not be necessary...
[Prognostic value of symptoms and signs of advanced heart failure and low left ventricle ejection fraction in patients after myocardial infarction with chronic heart failure]Marek Kuch
Akademia Medyczna w Warszawie, Katedra i Klinika Kardiologii II Wydziału Lekarskiego, Wojewódzki Szpital Bródnowski
Pol Merkur Lekarski 20:285-8. 2006..The aim of the study was evaluation if decreased LVEF worsen prognosis in pts with CHF and ALVD and whether LVEF is more powerful predictor of poor prognosis than severity of heart failure...
[Unfortunate outcome of subsequent vascular complications in female patients assigned to percutaneous coronary intervention -- case report]Zbigniew Tomik
I Katedra i Klinika Kardiologii Akademii Medycznej, ul Banacha 1a, 02 097 Warszawa
Kardiol Pol 64:506-12; discussion 512-3. 2006..However, the patient died due to intractable cardiogenic shock...
Congenital anomalies and developmental delay in a boy with double chromosome 6 derived supernumerary markerM Oldak
Department of Pediatric Diabetology, Neonatology and Birth Defects, Medical University of Warsaw, Dzialdowska 1, PL 01 184 Warsaw, Poland
Genet Couns 17:29-34. 2006..One cell line had a normal karyotype. In the other two either single or double chromosome 6 derived supernumerary markers were present, leading to partial trisomy or partial tetrasomy of chromosome 6, respectively...
[Standard operating procedures in ethic committees]Marek Czarkowski
Katedra i Klinika Chorób Wewnetrznych i Endokrynologii Akademii Medycznej w Warszawie
Pol Merkur Lekarski 20:249-53. 2006..These projects need support via public funding from our authorities...
[Time to diagnosis as an index of efficiency of the health care system--lymphoma study]Emilian Snarski
Kliniki Chorób Wewnetrznych, Hematologii i Onkologii Akademii Medycznej w Warszawie
Wiad Lek 59:58-60. 2006..In the group of patients with an enlargement of lymph nodes on presentation, we were not able to observe any changes in time to diagnosis...
[Statins in patients with renal failure--the current therapeutic status]Krzysztof J Filipiak
I Katedra i Klinika Kardiologii Akademii Medycznej w Warszawie
Przegl Lek 62:51-4. 2005..These are the ones that are not metabolised by the cytochrome P450 3A4 system--fluvastatin and pravastatin. The article summarizes the current therapeutic status of statin use in renal failure patients...
The protection of patients' rights in clinical trialsMarek Czarkowski
Department of Internal Medicine and Endocrinology, Medical University of Warsaw, ul Banacha 1a, 02 097 Warsaw, Poland
Sci Eng Ethics 12:131-8. 2006..The opinions of experts who have been reviewing medical research projects for several years may prove to be especially valuable in this setting...
[Effectiveness of therapeutic (NI, N2) modified radical neck dissection (MRND) in patients with laryngeal cancer]Robert Osmólski
Klinika Otolaryngologii CMKP, Szpital Bródnowski, Warszawa
Pol Merkur Lekarski 19:371-2. 2005..Efficacy of modified radical neck dissection in treatment of laryngeal cancer with node positive neck...
[Motor-evoked potentials in patients with diabetes mellitus type 1]Irena Sergiej-Monkiewicz
Zakład Informatyki Medycznej, Akademia Medyczna, ul Banacha 1a, 01 097 Warszawa
Neurol Neurochir Pol 39:451-7. 2005..The aim of the study was to assess the function of the central motor pathway in young patients with diabetes mellitus type 1 by use of transcranial and paravertebral magnetic stimulation...
A single-fibre EMG study of neuromuscular transmission in migraine patientsI Domitrz
Department of Neurology, Medical University, 1A Banacha Street, 02 097 Warsaw, Poland
Cephalalgia 25:817-21. 2005..We suggest that abnormal neuromuscular transmission detectable by SFEMG may reflect a genetically determined dysfunction of the P/Q Ca(2+) channels in a subgroup of migraineurs with aura...
Gas exchange abnormalities in patients listed for liver transplantationT Przybyłowski
Department of Internal Diseases, Pneumology and Allergology, Warsaw Medical University, Warsaw, Poland
J Physiol Pharmacol 57:313-23. 2006..01). In conclusion, all patients referred for OLT should be screened for gas exchange abnormalities. Such a workup should include not only PAO(2) but also DL(CO) and P(A-a)O(2) measurement together with contrast enhanced echocardiography...
Expression of the membrane complement regulatory proteins (CD55 and CD59) in human thymusDariusz Sladowski
Department of Transplantology and Central Tissue Bank, Centre of Biostructure Research, Medical University, Warsaw, Poland
Folia Histochem Cytobiol 44:263-7. 2006..The observed co-localization of CD59, CD55 and CD30L might suggest an involvement of the complement system in thymic selection in humans...
Metaplasia of chondrocytes into osteoblastsKrzysztof H Włodarski
Chair Histology and Embryology, Institute of Biostructural Research, Medical University of Warsaw, Zwirki and Wigury 61, 02 901 Warszawa, Poland
Folia Biol (Krakow) 54:75-80. 2006..In this review a summary and discussion of reports on chondrocyte transdifferentiation is given...
[Klotho - a new regulator of mineral homeostasis]Jacek Lukaszkiewicz
Katedra i Zakład Biochemii i Chemii Klinicznej, Wydział Farmaceutyczny, Warszawski Uniwersytet Medyczny, Warszawa
Endokrynol Pol 60:104-9. 2009..In that way Klotho becomes one of the main players in a complex and multilevel system of maintaining the mineral homeostasis of the organism...
Angioarchitecture of the venous and capillary system in heart defects induced by retinoic acid in miceAnna Ratajska
Department of Pathological Anatomy, Medical University of Warsaw, Chałubińskiego 5, Warsaw 02 004, Poland
Birth Defects Res A Clin Mol Teratol 85:599-610. 2009..Corrosion casting and immunohistochemical staining with anti-alpha smooth muscle actin and anti-CD34 was utilized to demonstrate the capillary plexus and venous system in control and malformed mouse hearts...
Leptin as a modulator of osteogenesisKrzysztof Włodarski
Department and Division of Histology and Embryology, Center for Bioastructure Research, Medical University of Warsaw
Ortop Traumatol Rehabil 11:1-6. 2009..This inhibitory effect of leptin mediated by activation of sympathetic nervous system can be abrogated by application of blood pressure-reducing beta-blockers, which also inhibit receptors of hypothalamic adrenergic neurons...
Biventricular noncompaction associated with left ventricular systolic and diastolic dysfunction and severe pulmonary hypertension in a young manMichal Ciurzynski
Department of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Lindleya 4, Poland
Circ J 73:2163-5. 2009..Pulmonary hypertension may be a consequence of increased pulmonary venous pressures caused by systolic and diastolic heart dysfunction secondary to noncompaction...
First isolation of Clostridium difficile PCR-ribotype 027/toxinotype III in PolandHanna Pituch
Chair and Department of Medical Microbiology, The Medical University of Warsaw, Warsaw, Poland
Pol J Microbiol 57:267-8. 2008..Antimicrobial susceptibility tests revealed high level resistance to erythromycin, moxifloxacin and gatifloxacin. This is a first report of the 027 strain of C. difficile in Poland...
Genetics of Meesmann corneal dystrophy: a novel mutation in the keratin 3 gene in an asymptomatic family suggests genotype-phenotype correlationJacek P Szaflik
Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
Mol Vis 14:1713-8. 2008..Seventeen mutations in KRT12 and two in KRT3 have been described so far. The purpose of this study was to investigate the genetic background of MCD in a Polish family...
[Burkholderia cepacia: a new pathogen causing nosocomial infections]Dariusz Lipowski
Klinika Chorób Zakaźnych dla Dorosłych Akademia Medyczna w Warszawie
Przegl Epidemiol 62:7-17. 2008..CONCLUSIONS: B. cepacia may be an etiologic agent of severe hospital acquired pneumonia and sepsis among immunocompromised patients. Clinically infection develops picture of superinfection and usually is life-threatening condition...
Synthesis of conformationally constrained aryl- or heteroarylpiperazinyl derivatives of selected imides as 5-HT1A receptor ligandsJerzy Kossakowski
Department of Medical Chemistry, Medical University, 3 Oczki St, 02 007 Warsaw, Poland
Molecules 11:615-25. 2006..Their structures were conformationally constrained by introducing rigid linkers containing unsaturated bonds or aromatic benzene rings. These compounds are expected to possess anxiolytic and antidepressant activity...
Results of liver transplantation for hepatocellular cancerKrzysztof Zieniewicz
Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Poland
Ann Transplant 12:11-4. 2007..Liver transplantation (LTx) for hepatocellular carcinoma (HCC) in cirrhotic liver is nowadays generally accepted treatment modality...
[Are dopamine agonists alternative therapy for levodopa in early stage of Parkinson's disease? No]Andrzej Friedman
Katedra i Klinika Neurologii Wydziału Nauki o Zdrowiu, Akademia Medyczna w Warszawie
Neurol Neurochir Pol 41:S10-3. 2007..Therefore the treatment of Parkinson's disease should be started with levodopa...
An association between vascular endothelial growth factor gene promoter polymorphisms and diabetic retinopathyJacek P Szaflik
Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland
Graefes Arch Clin Exp Ophthalmol 246:39-43. 2008..Reports have suggested that polymorphisms at positions -460 and -634 of the 5' untranslated region of the VEGF gene increase its basal promoter activity...
Synthesis of oxiran-2-ylmethyl and oxiran-2-ylmethoxy derivatives of some 4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-diones as potential beta-adrenolyticsJerzy Kossakowski
Department of Medical Chemistry, The Medical University of Warsaw, 3 Oczki Street, 02 007 Warsaw, Poland
Acta Pol Pharm 63:485-90. 2006..2.1.0(2,6)]dec-8-ene-3,5-dione have been prepared. The pharmacological profile of selected compounds was evaluated for their affinities at beta-adrenoceptors. The investigated compounds exhibit modest affinity for these receptors...
[Fungal peritonitis in patients on peritoneal dialysis]Ewa Wojtaszek
Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnetrznych AM w Warszawie
Pol Arch Med Wewn 116:678-82. 2006..Fungal peritonitis is a serious complication causes significant morbidity and mortality for patients on peritoneal dialysis. We reviewed our fungal peritonitis cases to analyse clinical features, treatment and predisposing factors...
Simultaneous transplantation of two allogeneic units of cord blood in an adult patient with acute myeloblastic leukemia: a case reportWiesław Wiktor-Jedrzejczyk
Department of Hematology, Oncology, and Internal Diseases, Medical University of Warsaw, Warsaw, Poland
Arch Immunol Ther Exp (Warsz) 53:364-8. 2005..This led to the idea of the simultaneous use of several units of cord blood which, combined, would fulfill the requirements for the necessary cell number for an adult recipient...
Enhanced pressor response to centrally administered vasopressin in WKY rats on high sodium dietTymoteusz Zera
Department of Experimental and Clinical Physiology, Medical University of Warsaw, 00 927 Warsaw, 26 28 Krakowskie Przedmieście St, Poland
Acta Neurobiol Exp (Wars) 65:145-50. 2005..These results suggest that the prolonged high sodium diet does not induce hypertension in WKY rats, but it enhances the pressor function of the central vasopressinergic system...
Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantationJ Wyzgal
Institute of Transplantology, Medical University of Warsaw, Warsaw, Poland
Transplant Proc 34:3185-7. 2002
"Functional-QEMG" a new reliable method in daily routine investigationJ Kopec
Department of Neurology, Medical University of Warsaw, Poland
Electromyogr Clin Neurophysiol 42:495-506. 2002..Our experience during last ten years shown that such dynamical analysis is very useful in correlation with the clinical picture of examined patient to make the final conclusion of EMG investigation...
Evaluation of locally induced osteoarthritis by the complete and incomplete Freund's adjuvant in mice. The application of DEXA measurementsK H Włodarski
Department of Histology and Embryology, Medical University of Warsaw, Poland
Folia Biol (Praha) 48:192-9. 2002..DEXA scans were evaluated and related to histological and bone ash content analyses. The morphological and quantitative ash weight analyses of bones exposed to the adjuvants were consistent with DEXA bone density scan measurements...
Locomotion of human granulocytes in viscous mediaJadwiga Jakubas-Przewłocka
Department of Biophysics, Medical University of Warsaw, Poland
Med Sci Monit 8:BR408-13. 2002..The purpose of this research was to study the influence of medium viscosity on granulocyte locomotion...
Serum arginase activity in postsurgical monitoring of patients with colorectal carcinomaZofia Porembska
Department of Biochemistry, Medical University of Warsaw, Warsaw, Poland
Cancer 94:2930-4. 2002..Colorectal carcinoma (CRC) is one of the most common malignancies. In the current work, the role of arginase as a diagnostic marker in patients with recurrent CRC and colorectal liver metastases (CRCLM) was studied...
Collecting and paramuscular venules in glandular mucosa of rat stomachStanislaw Moskalewski
Department of Histology, Medical University of Warsaw, Poland
Ann Anat 184:173-9. 2002....
In vitro culture of human epithelial cells on a modified xenogenic collagen supportE Lesiak-Cyganowska
Department of Transplantology and Central Tissue Bank, Centre of Biostructure Research, Warsaw Medical University, Poland
Arch Immunol Ther Exp (Warsz) 49:253-9. 2001..EDTA-incubated collagen enhanced neither adhesion nor proliferation. The best adhesion and proliferation were found on HCl-treated collagen, depending, however, on the kind of cells...
Acute appendicitis: the role of enterotoxigenic strains of Bacteroides fragilis and Clostridium difficileG Martirosian
Department of Histology and Embryology, Center for Biostructure Research, Medical University of Warsaw, ul Chałubińskiego 5, 02 004 Warsaw, Poland
Med Sci Monit 7:382-6. 2001..The aim of this study was to investigate whether there is a relationship between enterotoxin-producing B. fragilis strains and toxigenic C. difficile strains and the pathogenesis of acute appendicitis...
Proteasomes in apoptosis: villains or guardians?C Wojcik
Department of Histology and Embryology, Institute of Biostructure, Medical University of Warsaw, Warszawa, Poland
Cell Mol Life Sci 56:908-17. 1999....
Relationship between mast cells/parietal cells and maximal/basal acid output ratio in chronic gastritisD Biernacka
Department of Pathological Anatomy, Medical University of Warsaw, Poland
Res Exp Med (Berl) 200:35-41. 2000..The ratio of mast/parietal cells and the ratio of maximal and basal acid output were negatively correlated...
Prenatal development of coronary arteries in the rat: morphometric patternsA Ratajska
Department of Pathological Anatomy, Medical University of Warsaw, Poland
Folia Morphol (Warsz) 59:297-306. 2000..5-fold. The lumen of the proximal part of c.a. increased 4-fold during ED18-21. An increase in c.a. length is the fastest compared to the heart growth, and crown-rump growth during the foetal life...
Astrogliosis and blood vessel development during human spinal cord myelinationD Dziewulska
Department of Neurology, Medical University of Warsaw, Poland
Folia Neuropathol 38:61-7. 2000....
Interleukin 18--interferon gamma inducing factor--a novel player in tumour immunotherapy?J Gołąb
Department of Immunology, Institute of Biostructure, Medical University of Warsaw, Poland
Cytokine 12:332-8. 2000..A potential role of IL-18 in tumour immunotherapy is discussed in this article with special emphasis on the similarities with IL-12 and the potential mechanisms of its antitumour activity in preclinical models in mice...
[Diagnosis and treatment of thyroid nodules]Urszula Makowska
Katedra i Klinika Chorób Wewnetrznych i Endokrynologii Akademii Medycznej w Warszawie
Przegl Lek 59:859-61. 2002..Thyroxine therapy may be proposed to some patients but the possibility of side-effects should always be taken into account, as well as the low efficacy of this treatment...
[Correlation between bronchoscopically visible aspects and histopathologic results in patients with suspected lung cancer]Marcin Paciorek
Katedra i Klinika Chorób Wewnetrznych Pneumonologii i Alergologii AM w Warszawie
Pol Arch Med Wewn 108:1193-7. 2002..Examination of bronchial brushings coplements forceps biopsy in diagnosing and typing lung neoplasms and could be performed more frequently in patients undergoing fiberoptic bronchoscopy...
New HPLC method for separation of blood plasma phospholipidsZofia Suchocka
Department of Biochemistry and Clinical Chemistry, The Warsaw Medical University, 1 Banacha Str, 02 097 Warsaw, Poland
J Pharm Biomed Anal 32:859-65. 2003..This method made it possible to determine quantitatively: 5 microg ml(-1) PC, 1 microg ml(-1) LPC, 4 microg ml(-1) PE and 3 microg ml(-1) PI in blood plasma samples...
Cartilage formed by syngeneic rat chondrocytes in joint surface defects is rejected in animals sensitized with allogeneic chondrocytes: involvement of the synovial liningStanisław Moskalewski
Department of Histology and Embryology, Medical University of Warsaw, Warsaw, Poland
Arch Immunol Ther Exp (Warsz) 53:159-68. 2005..The aim of the study was to discover the mechanism of rejection of chondrocyte transplants introduced into articular cartilage defects...
Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?Monika Puzianowska-Kuznicka
Department of Endocrinology, Medical Research Center, Polish Academy of Sciences, 1A Banacha Street, 02 097 Warsaw, Poland
Int J Biochem Cell Biol 37:947-60. 2005..In this paper we present the clinical and molecular features of selected progeroid syndromes and describe the potential implications of these data for studies of ageing and cancer development...
Altered expression of angiotensin AT1a and vasopressin V1a receptors and nitric oxide synthase mRNA in the brain of rats with renovascular hypertensionE Jackiewicz
Department of Experimental and Clinical Physiology, Medical University of Warsaw, Krakowskie Przedmieście 26 28 str, 00 927 Warsaw, Poland
J Physiol Pharmacol 55:725-37. 2004..The study provides evidence for significant changes of expression of AT1aR mRNA, V1aR mRNA and NOS1 mRNA in the specific brain regions of rats with the renovascular hypertension...
Quantitative ultrastructural changes in satellite cells of rats immobilized after soleus muscle denervationMarek Kujawa
Department of Histology and Embryology, Center of Biostructure Research, Medical University of Warsaw, 02 004 Warsaw, Poland
Exp Mol Pathol 78:78-85. 2005..However, immobilization after denervation aggravated some of the ultrastructural alterations or the changes appeared earlier...
Impaired apoptosis of lymphocytes derived from patient with decreased expression of caspase-8 results in Alps-like phenotypeTomasz Grzela
Department of Histology and Embryology, Warsaw Medical University, PL 02 004 Warsaw, Poland
Int J Mol Med 14:937-42. 2004..However, the detailed molecular mechanism of observed abnormalities in caspase-8 expression remains to be elucidated...
Improvement in deep vein haemodynamics following surgery for varicose veinsP Ciostek
Second Medical Division, First Department and Chair of General and Vascular Surgery, Warsaw Medical Academy, Warsaw, Poland
Eur J Vasc Endovasc Surg 28:473-8. 2004..o analyse the effect of superficial and perforating veins surgery on deep vein incompetence...
Serum B-type natriuretic peptide levels on admission predict not only short-term death but also angiographic success of procedure in patients with acute ST-elevation myocardial infarction treated with primary angioplastyMarcin Grabowski
First Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
Am Heart J 148:655-62. 2004..Few data are available for BNP levels obtained on admission in patients with acute ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI)...
[Corticobasal degeneration: a case report and review of the literature]Piotr Janik
Katedra i Klinika Neurologii Akademii Medycznej w Warszawie
Neurol Neurochir Pol 38:329-34. 2004..In the present case, symptomatic treatment was ineffective. We emphasize that the diagnosis can be made during life based on clinical signs and neuroradiologic studies such as MRI, SPECT-HMPAO and proton magnetic resonance spectroscopy...
Synthesis of new hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives with an arylpiperazine moiety as ligands for 5-HT(1A) and 5-HT(2A) receptors, Part 2F Herold
Department of Drug Technology, Faculty of Pharmacy, The Medical University of Warsaw, Poland
Pharmazie 59:99-105. 2004..Compounds 11-16 and 23-27 were tested for their affinity towards 5-HT(1A), 5-HT(2A) and alpha1 receptors, using a radioligand binding assay...
Telemedicine in the context of different medical specialities. The Polish perspectiveRobert Rudowski
Department of Medical Informatics, Medical University, Warszawa
Pol J Pathol 54:219-21. 2003..In conclusion: the barriers of the development of telemedicine in Poland are caused by the organization of health service--Patients Funds using different software, no messaging standards and different reimbursement systems...
Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in miceWitold Lasek
Department of Immunology, Centre of Biostructure, Medical University of Warsaw, Chałubińskiego 5, 02 004 Warsaw, Poland
Cancer Immunol Immunother 53:363-72. 2004....
N-terminal pro-brain natriuretic peptide in patients with acute pulmonary embolismP Pruszczyk
Dept of Internal Medicine and Hypertension, Medical University of Warsaw, Warsaw, Poland
Eur Respir J 22:649-53. 2003..Acute pulmonary embolism should be considered in the differential diagnosis of patients with dyspnoea and abnormal levels of brain natriuretic peptide...
Tryptase levels in patients after acute coronary syndromes: the potential new marker of an unstable plaque?Krzysztof J Filipiak
Department of Internal Medicine and Cardiology, Warsaw Medical University School, Poland Central University Hospital, Warsaw, Poland
Clin Cardiol 26:366-72. 2003..Cardiac MC degranulation after myocardial ischemia has been documented in animal models. Cardiac MCs are highly profibrinolytic cells and release tryptase, their specific protease, after ischemic events...
Clinical anatomy of internal thoracic artery branchesK Pietrasik
Department of Anatomy, University Medical School of Warsaw, Warsaw, Poland
Clin Anat 12:307-14. 1999..This fact is crucial for creation of collateral blood supply to the sternum after bilateral ITA mobilizations...
