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Genomes and GenesSpecies | Grzegorz MazurSummaryCountry: Poland Publications
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Publications
IL-6 and IL-10 promoter gene polymorphisms do not associate with the susceptibility for multiple myelomaGrzegorz Mazur
Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Pasteura 4, 50 367 Wroclaw, Poland
Immunol Lett 96:241-6. 2005..However, the IL-6 polymorphic features appeared as factors that might affect the survival of MM patients. The latter observation warrants further study...- IL-6 and IL-10 promoter gene polymorphisms in psoriasis vulgarisWojciech Baran
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland
Acta Derm Venereol 88:113-6. 2008..No significant differences were found in the polymorphisms of IL-6 and IL-10 promoter genes between patients with psoriasis and healthy controls... - IFN gamma gene polymorphism may contribute to the susceptibility to CLLIwona Urbanowicz
Department of Clinical Chemistry, Wroclaw Medical University, Pasteur 2 str, 50 367, Wroclaw, Poland
Pathol Oncol Res 16:213-6. 2010..This results suggest that individuals rather prone to the lower level of IFN-gamma production (associated with the presence of the A allele) appear to be more susceptible to this malignant disease... - IFN-gamma promoter gene polymorphism in psoriasis vulgarisWojciech Baran
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland
Biomarkers 13:52-8. 2008..The results suggest that IFN-gamma polymorphism is associated with susceptibility to psoriasis vulgaris... - TGF-beta(1) gene polymorphism in psoriasis vulgarisWojciech Baran
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chalubinskiego 1, 50 368 Wroclaw, Poland
Cytokine 38:8-11. 2007..TGF-beta(1) gene polymorphism in codon 10 and 25 is not associated with susceptibility to psoriasis vulgaris, but may be important for the type of the disease... - Density of intranodal lymphatics and VEGF-C expression in B-cell lymphoma and reactive lymph nodesTomasz Wróel
Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University, Wrocław, Poland
Folia Histochem Cytobiol 44:43-7. 2006..NHL are not associated with increased expression of VEGF-C nor increased LYVE-1-positive lymphatic sinuses density within lymph nodes... - TGF-beta1 gene polymorphisms influence the course of the disease in non-Hodgkin's lymphoma patientsGrzegorz Mazur
Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland
Cytokine 33:145-9. 2006..302, p=0.057). TGF-beta1 gene polymorphisms were found to associate with the course of the disease in NHL patients. TGF-beta1 high producer genotype appeared as an independent risk factor of extranodal manifestation of the disease... - Angiogenesis measured by expression of CD34 antigen in lymph nodes of patients with non-Hodgkin's lymphomaGrzegorz Mazur
Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University, Wrocław, Poland
Folia Histochem Cytobiol 42:241-3. 2004..Nevertheless, angiogenesis observed in nHL provides rationale for use of angiogenesis inhibitors in lymphoma therapy... - Expression of cyclin A and bone morphogenetic protein receptors and response to induction therapy in patients with acute leukemiasJustyna Dzietczenia
Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland
Leuk Lymphoma 52:2336-41. 2011..The expressions of BMPRIA, BMPRIB, BMPRII and cyclin A could be useful as prognostic parameters of the proliferation status of acute leukemia cells, but further studies are needed to assess this phenomenon... - Asymmetric dimethylarginine in hematological malignancies: a preliminary studyAndrzej Szuba
Department of Internal Medicine, Wroclaw Medical University, Poland
Leuk Lymphoma 49:2316-20. 2008..Elevated ADMA plasma levels in patients with hematological malignancies interfere with nitric oxide metabolism and may influence their prognosis. Further prognostic studies are postulated to assess this phenomenon... - Proinflammatory chemokine gene expression influences survival of patients with non-Hodgkin's lymphomaGrzegorz Mazur
Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Poland
Folia Histochem Cytobiol 49:240-7. 2011..In the cases of CCL2 and CCL3, expression in lymphomas was higher than in reactive lymph nodes. Patients with high expression of CCL2 and CXCL10 had shorter survival... - A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patientsWojciech Baran
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Ul Chalubinskiego 1, 50 368 Wroclaw, Poland
Acta Dermatovenerol Alp Panonica Adriat 15:113-8. 2006..This study was performed to investigate the association between TNF-alpha single nucleotide polymorphism and susceptibility for psoriasis vulgaris... - Expression of complement regulatory proteins: CD46, CD55, and CD59 and response to rituximab in patients with CD20+ non-Hodgkin's lymphomaJustyna Dzietczenia
Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Pasteura 4 Street, Wroclaw, 50 367, Poland
Med Oncol 27:743-6. 2010..Expression of CD55 and CD59 were higher in patients with bulky disease. In conclusion level of expression of CD46, CD55, and CD59 could be clinically helpful to predict the response to rituximab therapy... - Elevated YB-1 expression is a new unfavorable prognostic factor in non-Hodgkin's lymphomasKatarzyna Szczuraszek
Department of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland
Anticancer Res 31:2963-70. 2011..Y-Box-binding protein-1 (YB-1) acts as a transcription factor for multiple genes and is linked to DNA replication and repair, cell proliferation and resistance to cytostatic drugs... - Expression of metallothionein (MT) and gluthatione s-transferase pi (SGTP) in the bone marrow of patients with myeloproliferative disorders (MPD)Tomasz Wrobel
Department of Haematology, Blood Neoplasm and Bone Marrow Transplantation, Medical University, Wrocław, Poland
Folia Morphol (Warsz) 63:129-31. 2004..These data, although based on a relatively small number of patients, raise the possibility that SGTP and MT may play a role in the pathogenesis of MPD. The clinical significance of this phenomenon needs further investigation... - Increased angiogenesis in cutaneous T-cell lymphomasGrzegorz Mazur
Department of Haematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw, Poland
Pathol Oncol Res 10:34-6. 2004..Increased MVD in the skin of CTCL patients indicate that angiogenesis may play a role in the growth of CTCL, and raises the possibility of using angiogenesis inhibitors in CTCL therapy... - [Familial incidence of myelodysplastic syndromes]Tomasz Wrobel
Z Kliniki Hematologii, Nowotworów Krwi i Transplantacji Szpiku Akademii Medycznej we Wrocławiu
Wiad Lek 59:285-8. 2006..There was absence of one mutagen common for every member of two reported families... - [Amyloidosis in the course of multiple myeloma]Grzegorz Mazur
Katedra i Klinika Hematologii,
Pol Arch Med Wewn 113:341-5. 2005..Among the multiple myeloma patients we found 17 with AL amyloid and 35 persons with elevated concentration of the serum SAA. The most frequent symptoms were related with renal failure and heart failure... - [Expression of serum vascular endothelial growth factor correlates with clinical outcome in multiple myeloma]Lidia Usnarska-Zubkiewicz
Klinika Hematologii,
Pol Arch Med Wewn 110:719-24. 2003..In summary: serum level of VEGF in advanced state of multiple myeloma was elevated and correlated with clinical state. An elevated serum level of VEGF is associated with a poor prognosis...