Affiliation: Jagiellonian University
- Chronic but not acute antidepresant treatment alters serum zinc/copper ratio under pathological/zinc-deficient conditions in miceK Mlyniec
Department of Biochemical Toxicology, Jagiellonian University Medical College, Cracow, Poland
J Physiol Pharmacol 65:673-8. 2014..Observed in this study normalization of serum Zn/Cu ratio in depression-like conditions by chronic (but not acute) antidepressants suggest that this ratio may be consider as a marker of depression or treatment efficacy. ..
- Essential elements in depression and anxiety. Part IKatarzyna Młyniec
Department of Biochemical Toxicology, Jagiellonian University Collegium Medicum, Krakow, Poland Institute of Pharmacology, Polish Academy of Sciences, Krakow, Poland Electronic address
Pharmacol Rep 66:534-44. 2014..Furthermore, administration of low dose antidepressants supplemented with an element is effective and can reduce unwanted side effects in different types of depression/anxiety. ..
- The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victimsKatarzyna Młyniec
Department of Toxicology, Jagiellonian University Medical College, Medyczna 9, PL 30 688 Krakow, Poland Institute of Pharmacology, Polish Academy of Sciences and Center of Excellence in Neuropsychopharmacology, Smetna 12, Pl 31 343 Krakow, Poland Electronic address
Neuropharmacology 79:290-7. 2014....
- Zinc deficiency alters responsiveness to antidepressant drugs in miceKatarzyna Młyniec
Department of Biochemical Toxicology, Jagiellonian University Medical College, Krakow, Poland
Pharmacol Rep 65:579-92. 2013..We examine also whether these changes are related to activity of the hypothalamic-pituitary-adrenal HPA axis...
- GPR39 up-regulation after selective antidepressantsKatarzyna Młyniec
Department of Biochemical Toxicology, Jagiellonian University Medical College, Medyczna 9, PL 30 688 Krakow, Poland
Neurochem Int 62:936-9. 2013..This is the first report to indicate the involvement of the GPR39 Zn²⁺-sensing receptor in the antidepressant effect of selective monoamine reuptake inhibitors...
- The role of the GPR39 receptor in zinc deficient-animal model of depressionKatarzyna Młyniec
Department of Biochemical Toxicology, Jagiellonian University Medical College, Medyczna 9, PL 30 0688 Kraków, Poland
Behav Brain Res 238:30-5. 2013..Our study provides evidence that the GPR39 Zn(2+)-sensing receptor may be responsible for lowering the BDNF protein level and in consequence may be involved in the pathogenesis of depression...
- Time course of zinc deprivation-induced alterations of mice behavior in the forced swim testKatarzyna Młyniec
Department of Pharmacobiology, Jagielonian University Medical Colege, Medyczna 9, PL 30 688 Krakow, Poland
Pharmacol Rep 64:567-75. 2012..It is hypothesized that zinc may be a therapeutic agent or supplement that would help to reverse the symptoms of this disease...
- Zinc deficiency induces behavioral alterations in the tail suspension test in mice. Effect of antidepressantsKatarzyna Młyniec
Department of Pharmacobiology, Faculty of Pharmacy, Jagielonian University Medical College, Medyczna 9, PL 30 688 Krakow, Poland
Pharmacol Rep 64:249-55. 2012..Recently, experimental zinc deficiency has been correlated with depression-like alterations in rodents...
- Zinc deficiency in rats is associated with up-regulation of hippocampal NMDA receptorUrszula Doboszewska
Department of Neurobiology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, Pl 31 343 Krakow, Poland
Prog Neuropsychopharmacol Biol Psychiatry 56:254-63. 2015..Data indicated that zinc deficiency may contribute to the development of depression; however changes induced by zinc deficiency are not fully described...
- Early lifetime zinc supplementation protects zinc-deficient diet-induced alterationsWłodzimierz Opoka
Department of Inorganic Chemistry, Jagiellonian University, Collegium Medicum, Medyczna 9, PL 30 688 Krakow, Poland
Pharmacol Rep 62:1211-7. 2010..These results indicate that post-birth supplementation with zinc may protect zinc-deficient diet-induced rapid alterations in zinc homeostasis...
- Zinc as a marker of affective disordersMarcin Siwek
Department of Psychiatry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 21a, PL 31 501 Krakow, Poland
Pharmacol Rep 65:1512-8. 2013..It seems, however, that the measurement of the concentrations of zinc might be in the future a component of the battery of tests; of markers of immune activation and oxidative stress rather than itself alone. ..
- Antidepressant-like effect of chromium chloride in the mouse forced swim test: involvement of glutamatergic and serotonergic receptorsAnna Piotrowska
Laboratory of Pharmacobiology, Department of Cytobiology and Histochemistry, Collegium Medicum, Jagiellonian University, Medyczna 9, PL 30 688 Krakow, Poland
Pharmacol Rep 60:991-5. 2008....