Marta J Siemieniuch
Affiliation: Institute of Animal Reproduction and Food Research
Jursza E, Skarzynski D, Siemieniuch M. Validation of reference genes in the feline endometrium. Reprod Biol. 2014;14:302-6 pubmed publisher
..Based on geNorm results at least two genes from among RPS7, RPL30, ACTB or YWHAZ should be chosen for Real Time-PCR result normalization. ..
Gajos K, Kozdrowski R, Nowak M, Siemieniuch M. Altered secretion of selected arachidonic acid metabolites during subclinical endometritis relative to estrous cycle stage and grade of fibrosis in mares. Theriogenology. 2015;84:457-66 pubmed publisher
Jursza Piotrowska E, Socha P, Skarzynski D, Siemieniuch M. Prostaglandin release by cultured endometrial tissues after challenge with lipopolysaccharide and tumor necrosis factor Î±, in relation to the estrous cycle, treatment with medroxyprogesterone acetate, and pyometra. Theriogenology. 2016;85:1177-85 pubmed publisher
..Data gathered from endometrial cell culture and endometrial organ culture lead to the conclusion that disturbances in prostaglandin release contribute to pyometra in cats. ..
Jursza Piotrowska E, Siemieniuch M. Identifying diagnostic endocrine markers and changes in endometrial gene expressions during pyometra in cats. Reprod Biol. 2016;16:174-80 pubmed publisher
..In addition, treatment with MPA evoked neither endocrine nor molecular changes in endometria of cats. ..
Siemieniuch M, Jursza E, Kowalewski M, Majewska M, Skarzynski D. Prostaglandin endoperoxide synthase 2 (PTGS2) and prostaglandins F2? and E2 synthases (PGFS and PGES) expression and prostaglandin F2? and E2 secretion following oestrogen and/or progesterone stimulation of the feline endometrium. Reprod Domest Anim. 2013;48:72-8 pubmed publisher
..These data support the hypothesis that ovarian sex steroids via endometrial PGE(2) are involved in endocrine homoeostasis, especially at oestrus and the mid, but not the late, phase of pseudopregnancy in cats. ..
Siemieniuch M, Jursza E, Szostek A, Skarzynski D, Boos A, Kowalewski M. Steroidogenic capacity of the placenta as a supplemental source of progesterone during pregnancy in domestic cats. Reprod Biol Endocrinol. 2012;10:89 pubmed publisher
..These results confirm that the placenta is an additional source of P4 in pregnant queens and can thereby be considered as an important endocrine organ supporting feline pregnancy. ..
Jursza E, Kowalewski M, Boos A, Skarzynski D, Socha P, Siemieniuch M. The role of toll-like receptors 2 and 4 in the pathogenesis of feline pyometra. Theriogenology. 2015;83:596-603 pubmed publisher
Nowaczyk R, Jursza Piotrowska E, Gram A, Siemieniuch M, Boos A, Kowalewski M. Cells expressing CD4, CD8, MHCII and endoglin in the canine corpus luteum of pregnancy, and prepartum activation of the luteal TNFÎ± system. Theriogenology. 2017;98:123-132 pubmed publisher
..Contrasting with the slow luteal regression in non-pregnant dogs, in pregnant animals the upregulation of TNFR2 expression during prepartum luteolysis implies functional involvement of the TNFÎ± system during that time. ..
Siemieniuch M, Gajos K, Kozdrowski R, Nowak M. Advanced age in mares affects endometrial secretion of arachidonic acid metabolites during equine subclinical endometritis. Theriogenology. 2017;103:191-196 pubmed publisher
..We conclude that advanced age in mares further disturbs the immuno-endocrine balance in endometritis-positive mares. ..