Anna J Korzekwa
Affiliation: Institute of Animal Reproduction and Food Research
Korzekwa A, Bodek G, Bukowska J, Blitek A, Skarzynski D. Characterization of bovine immortalized luteal endothelial cells: action of cytokines on production and content of arachidonic acid metabolites. Reprod Biol Endocrinol. 2011;9:27 pubmed publisher
..TNFalpha and IFNgamma modulate EnCL-1 cell function. Moreover, established EnCL-1 cell line appears to be a good model for investigating the molecular mechanisms related to cytokines action and aa metabolites production in cattle. ..
Åupicka M, Bodek G, Shpigel N, Elnekave E, Korzekwa A. Identification of pluripotent cells in bovine uterus: in situ and in vitro studies. Reproduction. 2015;149:317-27 pubmed publisher
..The highest mRNA and protein expression for pluripotent markers was observed in stromal cells among uterine cells, which indicates this population of cells as the main site of pluripotent cells in the cow uterus. ..
Åupicka M, Socha B, SzczepaÅ„ska A, Korzekwa A. Expression of pluripotency markers in the bovine uterus with adenomyosis. Reprod Biol Endocrinol. 2015;13:110 pubmed publisher
..The results indicate significant changes in expression of pluripotency markers in adenomyotic compared to normal uteri, which suggest the involvement of uterine stem cells in adenomyosis. ..
Korzekwa A, SzczepaÅ„ska A, Bogdaszewski M, Nadolski P, MalÅ¼ P, GiÅ¼ejewski Z. Production of prostaglandins in placentae and corpus luteum in pregnant hinds of red deer (Cervus elaphus). Theriogenology. 2016;85:762-8 pubmed publisher
..Further studies are required to unravel the mechanisms involved in the regulation of PG and biosynthetic enzymes in uteroplacental and ovarian tissues during pregnancy in red deer females. ..
Korzekwa A, Łupicka M, Socha B, Szczepańska A, Piotrowicz E, Baranski W. In vitro cow uterine response to Escherichia coli, leukotrienes and cytokines. Vet Immunol Immunopathol. 2016;182:59-62 pubmed publisher
..coli after 12 and 24h (P<0.05). LTs modify and enhance experimentally induced infection: TLR4 and IL-6 mRNA expression, IL-6 and PGs secretion, and cytokines participate in this process. ..
SzczepaÅ„ska A, Åupicka M, Socha B, Korzekwa A. The influence of arachidonic acid metabolites on PPAR and RXR expression in bovine uterine cells. Gen Comp Endocrinol. 2018;: pubmed publisher
..This study revealed the reaction of PPARs and RXRs to agonists which naturally occur in the bovine uterus. ..
Korzekwa A, Bah M, Kurzynowski A, Lukasik K, Groblewska A, Skarzynski D. Leukotrienes modulate secretion of progesterone and prostaglandins during the estrous cycle and early pregnancy in cattle: an in vivo study. Reproduction. 2010;140:767-76 pubmed publisher
..LTs are produced/secreted in the CL tissue, influence prostaglandin function, and serve as important factors during the estrous cycle and early pregnancy in cattle...
Łupicka M, Socha B, Szczepańska A, Korzekwa A. Prolactin role in the bovine uterus during adenomyosis. Domest Anim Endocrinol. 2017;58:1-13 pubmed publisher
..These data suggest involvement of PRL in adenomyosis development and the link between PRL and E2 actions during the dysfunction in cows. ..
Socha B, Åupicka M, SzczepaÅ„ska A, Korzekwa A. PPAR expression throughout the oestrous cycle in the bovine endometrium. Theriogenology. 2017;100:88-94 pubmed publisher
..Our findings suggest an association between the expression of PPARs in the bovine endometrium and stage of the oestrous cycle that may be a consequence of changes in ovarian steroids. ..