A Czlonkowska

Summary

Affiliation: Institute of Psychiatry and Neurology
Country: Poland

Publications

  1. pmc Concordance rates of Wilson's disease phenotype among siblings
    Grzegorz Chabik
    2nd Department of Neurology, Institute of Psychiatry and Neurology, 9 Sobieskiego Str, 02 957, Warsaw, Poland
    J Inherit Metab Dis 37:131-5. 2014
  2. ncbi Does brain degeneration in Wilson disease involve not only copper but also iron accumulation?
    Marta Skowronska
    Prof Anna Członkowska, II Klinika Neurologii, Instytut Psychiatrii i Neurologii, ul Sobieskiego 9, 02 957 Warszawa, tel 48 22 458 26 66, E mail
    Neurol Neurochir Pol 47:542-6. 2013
  3. pmc Influence of BDNF polymorphisms on Wilson's disease susceptibility and clinical course
    Dagmara Mirowska-Guzel
    Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 00 927, Warsaw, Poland
    Metab Brain Dis 28:447-53. 2013
  4. ncbi [Management of acute stroke - guidelines from the Expert Group of the Section of Cerebrovascular Diseases of the Polish Neurological Society. Update 2013: thrombolysis]
    A Członkowska
    Instytut Psychiatrii i Neurologii, ul Sobieskiego 9, Warszawa, Poland
    Neurol Neurochir Pol 47:303-9. 2013
  5. pmc Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
    Peter Sandercock
    The IST 3 Co ordinating Centre, Neurosciences Trial Unit, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Trials 12:252. 2011
  6. pmc The International Stroke Trial database
    Peter A G Sandercock
    Department of Clinical Neurosciences, University of Edinburgh, Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK
    Trials 12:101. 2011
  7. ncbi [Evaluation of needs in early post-stroke rehabilitation in Poland]
    Anna Członkowska
    II Klinika Neurologii, Instytut Psychiatrii i Neurologii, Warszawa, Poland
    Neurol Neurochir Pol 40:471-7. 2006
  8. ncbi High early case fatality after ischaemic stroke in Poland: exploration of possible explanations in the International Stroke Trial
    Anna Członkowska
    Second Department of Neurology, The Institute of Psychiatry and Neurology, 1 9 Sobieski Street, Warsaw 02 957, Poland
    J Neurol Sci 202:53-7. 2002
  9. ncbi [Multiple sclerosis and antiphospholipid syndrome--difficulties in differential diagnostics]
    Anna Członkowska
    II Klinika Neurologii, Instytut Psychiatrii i Neurologii, Warszawa
    Pol Arch Med Wewn 117:28-32. 2007
  10. doi Monozygotic female twins discordant for phenotype of Wilson's disease
    Anna Członkowska
    Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Mov Disord 24:1066-9. 2009

Detail Information

Publications37

  1. pmc Concordance rates of Wilson's disease phenotype among siblings
    Grzegorz Chabik
    2nd Department of Neurology, Institute of Psychiatry and Neurology, 9 Sobieskiego Str, 02 957, Warsaw, Poland
    J Inherit Metab Dis 37:131-5. 2014
    ..These results demonstrate a high intra-familial concordance of the clinical and biochemical presentation of WD, suggesting that similar factors shared within the same families strongly influence the disease presentation...
  2. ncbi Does brain degeneration in Wilson disease involve not only copper but also iron accumulation?
    Marta Skowronska
    Prof Anna Członkowska, II Klinika Neurologii, Instytut Psychiatrii i Neurologii, ul Sobieskiego 9, 02 957 Warszawa, tel 48 22 458 26 66, E mail
    Neurol Neurochir Pol 47:542-6. 2013
    ..We investigated whether WD patients have MRI changes suggesting iron accumulation using T2*-weighted and VEN_BOLD SWI imaging protocols...
  3. pmc Influence of BDNF polymorphisms on Wilson's disease susceptibility and clinical course
    Dagmara Mirowska-Guzel
    Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 00 927, Warsaw, Poland
    Metab Brain Dis 28:447-53. 2013
    ..0097). No association was detected between any of the determined polymorphisms and the dominant form of the disease or the age of onset for WD...
  4. ncbi [Management of acute stroke - guidelines from the Expert Group of the Section of Cerebrovascular Diseases of the Polish Neurological Society. Update 2013: thrombolysis]
    A Członkowska
    Instytut Psychiatrii i Neurologii, ul Sobieskiego 9, Warszawa, Poland
    Neurol Neurochir Pol 47:303-9. 2013
    ..They point out the possible benefit of thrombolysis in patients not meeting the current criteria, which has been acknowledged in the Polish guidelines for management of stroke. ..
  5. pmc Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
    Peter Sandercock
    The IST 3 Co ordinating Centre, Neurosciences Trial Unit, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Trials 12:252. 2011
    ..IST-3 sought to improve the external validity and precision of the estimates of the overall treatment effects (efficacy and safety) of rtPA in acute ischaemic stroke, and to determine whether a wider range of patients might benefit...
  6. pmc The International Stroke Trial database
    Peter A G Sandercock
    Department of Clinical Neurosciences, University of Edinburgh, Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK
    Trials 12:101. 2011
    ....
  7. ncbi [Evaluation of needs in early post-stroke rehabilitation in Poland]
    Anna Członkowska
    II Klinika Neurologii, Instytut Psychiatrii i Neurologii, Warszawa, Poland
    Neurol Neurochir Pol 40:471-7. 2006
    ..According to European Stroke Initiative (EUSI) recommendations every stroke patient should undergo rehabilitation. We aimed to evaluate the needs of comprehensive stroke in-patient rehabilitation in Poland...
  8. ncbi High early case fatality after ischaemic stroke in Poland: exploration of possible explanations in the International Stroke Trial
    Anna Członkowska
    Second Department of Neurology, The Institute of Psychiatry and Neurology, 1 9 Sobieski Street, Warsaw 02 957, Poland
    J Neurol Sci 202:53-7. 2002
    ..To determine why Polish patients included in the International Stroke Trial (IST) had a higher early case fatality than patients from other countries...
  9. ncbi [Multiple sclerosis and antiphospholipid syndrome--difficulties in differential diagnostics]
    Anna Członkowska
    II Klinika Neurologii, Instytut Psychiatrii i Neurologii, Warszawa
    Pol Arch Med Wewn 117:28-32. 2007
    ..That is why antiphospholipid antibodies must be concerned in differential diagnostics of multiple sclerosis, particularly with the atypical course and clinical pattern...
  10. doi Monozygotic female twins discordant for phenotype of Wilson's disease
    Anna Członkowska
    Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Mov Disord 24:1066-9. 2009
    ..Her sister remained clinically presymptomatic at diagnosis at the age of 28. We concluded that the phenotypic characteristics of WD are possibly attributable to epigenetic/environmental factors...
  11. doi Clinical features of hemolysis, elevated liver enzymes, and low platelet count syndrome in undiagnosed Wilson disease: report of two cases
    Anna Członkowska
    Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, Warsaw, Poland
    Arch Gynecol Obstet 281:129-34. 2010
    ..In pregnant patients with unrecognized WD, liver failure with hemolysis may be interpreted as the low platelet count (HELLP) syndrome...
  12. doi Pharmacotherapy in stroke rehabilitation
    Anna Członkowska
    Institute of Psychiatry and Neurology, 2nd Dept of Neurology, 9 Sobieskiego Str, 02 957 Warsaw, Poland
    Expert Opin Pharmacother 10:1249-59. 2009
    ..Pharmacotherapy is commonly given to patients recovering from a stroke to prevent further complications (e.g. recurrent stroke, seizures) or enhance recovery. However, some drugs may have a negative impact on neuroplasticity...
  13. doi Ten years of stroke programmes in Poland: where did we start? Where did we get to?
    Anna Członkowska
    2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Int J Stroke 5:414-6. 2010
    ..Continuous monitoring of patient care proved that the mortality and disability rates have decreased and the quality of treatment has improved...
  14. doi Inflammation and gliosis in neurological diseases--clinical implications
    Anna Członkowska
    2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    J Neuroimmunol 231:78-85. 2011
    ..Manipulation of the inflammation is now one of the approaches in the treatment of the various diseases of the CNS...
  15. ncbi Unified Wilson's Disease Rating Scale - a proposal for the neurological scoring of Wilson's disease patients
    Anna Członkowska
    2nd Neurological Department, Institute of Psychiatry and Neurology, Warsaw, Poland
    Neurol Neurochir Pol 41:1-12. 2007
    ..The aim of the study was to develop a novel rating scale for WD, because as far as we know no scale for the clinical rating in WD has been designed before...
  16. ncbi Estrogen and cytokines production - the possible cause of gender differences in neurological diseases
    A Czlonkowska
    Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02 957 Warsaw, Poland
    Curr Pharm Des 11:1017-30. 2005
    ....
  17. ncbi Wilson's disease-cause of mortality in 164 patients during 1992-2003 observation period
    A Członkowska
    J Neurol 252:698-703. 2005
    ..There was no difference in mortality rate in patients treated with d-penicillamine or zinc sulphate as initial therapy. The prognosis for survival in the majority of WD patients is favourable, provided that therapy is introduced early...
  18. ncbi APOE genotype and serum cholesterol in predicting risk for early death from ischemic stroke in men and women
    Grazyna Gromadzka
    Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Cerebrovasc Dis 20:291-8. 2005
    ..A significant association of low serum cholesterol level with increased risk of death from stroke was documented. So, we aimed to establish if an association exists between APOE genotype, serum cholesterol and 1-month mortality in IS...
  19. ncbi [Evaluation of the accessibility of stroke units in Poland]
    Anna Członkowska
    II Klinika Neurologii, Instytut Psychiatrii i Neurologii w Warszawie, Warsaw, Poland
    Neurol Neurochir Pol 38:353-60. 2004
    ..The aim of our study was to evaluate the accessibility and eligibility of stroke units in Poland...
  20. ncbi [An evaluation of the accessibility of early post-stroke comprehensive rehabilitation in Poland]
    Anna Członkowska
    II Klinika Neurologii, Instytut Psychiatrii i Neurologii w Warszawie
    Neurol Neurochir Pol 40:10-5. 2006
    ..The aim of our study was to evaluate the accessibility of comprehensive early stroke rehabilitation at neurological departments in Poland...
  21. ncbi Gender differences in neurological disease: role of estrogens and cytokines
    Anna Członkowska
    Institute of Psychiatry and Neurology, Second Department of Neurology, Warsaw, Poland
    Endocrine 29:243-56. 2006
    ....
  22. ncbi The polish experience in early stroke care
    Anna Członkowska
    Institute of Psychiatry and Neurology, Medical School, Warsaw, Poland
    Cerebrovasc Dis 15:14-5. 2003
    ..Significant differences in stroke fatality were noted between well- and as yet insufficiently organised units. These results indicate a need for monitoring the implementation of the basic standards in stroke units...
  23. ncbi The APOE polymorphism and 1-year outcome in ischemic stroke: genotype-gender interaction
    G Gromadzka
    Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, Warsaw, Poland
    Acta Neurol Scand 116:392-8. 2007
    ..We aimed to evaluate whether the APOE genotype is related to acute neurological impairments due to ischemic stroke (IS), and to outcomes (up to 1 year) indicated by severe functional disability, dependence in daily living or death...
  24. ncbi Factors predicting early stroke fatality in Poland. Preliminary report of the Polish National Stroke Registry
    D Ryglewicz
    Institute of Psychiatry and Neurology, 1st Department of Neurology, Sobieskiego 1, 02 957 Warsaw, Poland
    Neurol Sci 24:301-4. 2003
    ..2% vs. 62.6%), early rehabilitation was delayed (38.3% vs. 73.4%), and secondary prevention treatment was prescribed to fewer patients (antiplatelettherapy 36.4% vs. 77.4%; antithrombotic therapy 4.9% vs. 13%)...
  25. doi Intravenous recombinant tissue plasminogen activator for acute stroke in Poland: an analysis based on the Safe Implementation of Thrombolysis in Stroke (SITS) Registry
    A Kobayashi
    2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Acta Neurol Scand 122:229-36. 2010
    ..The aim of this study is to compare the safety and efficacy of thrombolysis in the Polish SITS-ISTR stroke patient population with patients registered in SITS-MOST...
  26. pmc IL1RN intron 2 polymorphism caused by variable number tandem repeats is associated with 1-year outcome in patients with ischaemic stroke
    G Gromadzka
    Institute of Psychiatry and Neurology 2 Medical University, Warsaw, Poland
    J Neurol Neurosurg Psychiatry 78:183-6. 2007
    ..In humans, IL1ra is encoded by the IL1RN gene located on chromosome 2...
  27. doi Do silent infarcts modify the effect of thrombolysis for stroke?
    A Kobayashi
    2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
    Acta Neurol Scand 127:227-32. 2013
    ..Our aim was to identify the prevalence of SBI in acute ischaemic stroke patients undergoing routine intravenous thrombolysis and evaluate the association between their presence on pretreatment computed tomography (CT) and outcome...
  28. ncbi Factor V Leiden, prothrombin gene G20210A variant, and methylenetetrahydrofolate reductase C677T genotype in young adults with ischemic stroke
    S Lopaciuk
    Institute of Hematology and Blood Transfusion, Warsaw, Poland
    Clin Appl Thromb Hemost 7:346-50. 2001
    ..In conclusion, our results indicate that FV Leiden mutation, prothrombin G20210A genotype, and homozygosity for the C677T mutation in the MTHFR gene are not associated with an increased risk for ischemic stroke in young adults...
  29. ncbi A prospective study of the financial costs of multiple sclerosis at different stages of the disease
    E Orlewska
    Department of Clinical and Experimental Pharmacology, Medical University of Warsaw, Warsaw, Poland
    Eur J Neurol 12:31-9. 2005
    ..This study confirms that MS represents a high economic burden, with indirect costs greatly exceeding direct costs. As costs increase with disease progression, treatment efforts should focus on patients in the early stages of MS...
  30. ncbi Sonographic detection of basal ganglia lesions in asymptomatic and symptomatic Wilson disease
    U Walter
    Department of Neurology, University of Rostock, Rostock, Germany
    Neurology 64:1726-32. 2005
    ..To investigate whether transcranial brain parenchyma sonography (TCS) detects basal ganglia abnormalities in asymptomatic and symptomatic patients with Wilson disease (WD) and whether findings correlate with disease severity...
  31. ncbi Relative effects of statin therapy on stroke and cardiovascular events in men and women: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study
    Larry B Goldstein
    Duke University Medical Center, Durham, NC 27710, USA
    Stroke 39:2444-8. 2008
    ..9 years of follow-up. The purpose of this secondary analysis was to determine whether men and women similarly benefited from randomization to statin treatment...
  32. ncbi Variation in the management of acute physiological parameters after ischaemic stroke: a European perspective
    A Bhalla
    Department of Public Health Sciences, Guy s, King s and St Thomas School of Medicine, London, UK
    Eur J Neurol 10:25-33. 2003
    ..Further research is required to link variation in acute care with stroke outcome, to identify which interventions appear to be the most effective...
  33. doi Alemtuzumab vs. interferon beta-1a in early multiple sclerosis
    Alasdair J Coles
    N Engl J Med 359:1786-801. 2008
    ..Alemtuzumab, a humanized monoclonal antibody that targets CD52 on lymphocytes and monocytes, may be an effective treatment for early multiple sclerosis...
  34. doi Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
    Werner Hacke
    Department of Neurology, Universitat Heidelberg, Heidelberg, Germany
    N Engl J Med 359:1317-29. 2008
    ..We tested the efficacy and safety of alteplase administered between 3 and 4.5 hours after the onset of a stroke...
  35. ncbi Predicting outcome in hyper-acute stroke: validation of a prognostic model in the Third International Stroke Trial (IST3)
    Steff C Lewis
    J Neurol Neurosurg Psychiatry 79:397-400. 2008
    ..The explanatory variables in the model are age, living alone, independent pre-stroke, Glasgow Coma Scale verbal score, ability to lift arms and ability to walk...
  36. ncbi Increase of matrix metalloproteinase-9 in peripheral blood of multiple sclerosis patients treated with high doses of methylprednisolone
    D Mirowska
    Section of Neurology, Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    J Neuroimmunol 146:171-5. 2004
    ..No effect was noted on TIMP-1 and MMP-2 levels. The short-lived increase of MMP-9 plasma levels may be at least in part due to an activation and an increase of granulocytes and monocytes by methylprednisolone...
  37. ncbi Three novel mutations (P760L, L1305P, Q1351Stop) causing Wilson disease
    J Genschel
    Campus Charite Mitte, Med Klinik m S Gastroenterologie, Hepatologie und Endokrinologie, Berlin, Germany
    Hum Mutat 17:156. 2001