Research Topics
Species | A CzlonkowskaSummaryAffiliation: Institute of Psychiatry and Neurology Country: Poland Publications
| Collaborators
|
Detail Information
Publications
Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruitedPeter Sandercock
The IST 3 Co ordinating Centre, Neurosciences Trial Unit, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
Trials 12:252. 2011..IST-3 sought to improve the external validity and precision of the estimates of the overall treatment effects (efficacy and safety) of rtPA in acute ischaemic stroke, and to determine whether a wider range of patients might benefit...
The International Stroke Trial databasePeter A G Sandercock
Department of Clinical Neurosciences, University of Edinburgh, Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK
Trials 12:101. 2011....
[Evaluation of needs in early post-stroke rehabilitation in Poland]Anna Członkowska
II Klinika Neurologii, Instytut Psychiatrii i Neurologii, Warszawa, Poland
Neurol Neurochir Pol 40:471-7. 2006..According to European Stroke Initiative (EUSI) recommendations every stroke patient should undergo rehabilitation. We aimed to evaluate the needs of comprehensive stroke in-patient rehabilitation in Poland...
APOE genotype and serum cholesterol in predicting risk for early death from ischemic stroke in men and womenGrazyna Gromadzka
Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
Cerebrovasc Dis 20:291-8. 2005..A significant association of low serum cholesterol level with increased risk of death from stroke was documented. So, we aimed to establish if an association exists between APOE genotype, serum cholesterol and 1-month mortality in IS...
[An evaluation of the accessibility of early post-stroke comprehensive rehabilitation in Poland]Anna Członkowska
II Klinika Neurologii, Instytut Psychiatrii i Neurologii w Warszawie
Neurol Neurochir Pol 40:10-5. 2006..The aim of our study was to evaluate the accessibility of comprehensive early stroke rehabilitation at neurological departments in Poland...
Gender differences in neurological disease: role of estrogens and cytokinesAnna Członkowska
Institute of Psychiatry and Neurology, Second Department of Neurology, Warsaw, Poland
Endocrine 29:243-56. 2006....
Unified Wilson's Disease Rating Scale - a proposal for the neurological scoring of Wilson's disease patientsAnna Członkowska
2nd Neurological Department, Institute of Psychiatry and Neurology, Warsaw, Poland
Neurol Neurochir Pol 41:1-12. 2007..The aim of the study was to develop a novel rating scale for WD, because as far as we know no scale for the clinical rating in WD has been designed before...
Pharmacotherapy in stroke rehabilitationAnna Członkowska
Institute of Psychiatry and Neurology, 2nd Dept of Neurology, 9 Sobieskiego Str, 02 957 Warsaw, Poland
Expert Opin Pharmacother 10:1249-59. 2009..Pharmacotherapy is commonly given to patients recovering from a stroke to prevent further complications (e.g. recurrent stroke, seizures) or enhance recovery. However, some drugs may have a negative impact on neuroplasticity...
Clinical features of hemolysis, elevated liver enzymes, and low platelet count syndrome in undiagnosed Wilson disease: report of two casesAnna Członkowska
Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, Warsaw, Poland
Arch Gynecol Obstet 281:129-34. 2010..In pregnant patients with unrecognized WD, liver failure with hemolysis may be interpreted as the low platelet count (HELLP) syndrome...
[Multiple sclerosis and antiphospholipid syndrome--difficulties in differential diagnostics]Anna Członkowska
II Klinika Neurologii, Instytut Psychiatrii i Neurologii, Warszawa
Pol Arch Med Wewn 117:28-32. 2007..That is why antiphospholipid antibodies must be concerned in differential diagnostics of multiple sclerosis, particularly with the atypical course and clinical pattern...
Ten years of stroke programmes in Poland: where did we start? Where did we get to?Anna Członkowska
2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
Int J Stroke 5:414-6. 2010..Continuous monitoring of patient care proved that the mortality and disability rates have decreased and the quality of treatment has improved...
Estrogen and cytokines production - the possible cause of gender differences in neurological diseasesA Czlonkowska
Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02 957 Warsaw, Poland
Curr Pharm Des 11:1017-30. 2005....
High early case fatality after ischaemic stroke in Poland: exploration of possible explanations in the International Stroke TrialAnna Członkowska
Second Department of Neurology, The Institute of Psychiatry and Neurology, 1 9 Sobieski Street, Warsaw 02 957, Poland
J Neurol Sci 202:53-7. 2002..To determine why Polish patients included in the International Stroke Trial (IST) had a higher early case fatality than patients from other countries...
The polish experience in early stroke careAnna Członkowska
Institute of Psychiatry and Neurology, Medical School, Warsaw, Poland
Cerebrovasc Dis 15:14-5. 2003..Significant differences in stroke fatality were noted between well- and as yet insufficiently organised units. These results indicate a need for monitoring the implementation of the basic standards in stroke units...
Inflammation and gliosis in neurological diseases--clinical implicationsAnna Członkowska
2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
J Neuroimmunol 231:78-85. 2011..Manipulation of the inflammation is now one of the approaches in the treatment of the various diseases of the CNS...
[Evaluation of the accessibility of stroke units in Poland]Anna Członkowska
II Klinika Neurologii, Instytut Psychiatrii i Neurologii w Warszawie, Warsaw, Poland
Neurol Neurochir Pol 38:353-60. 2004..The aim of our study was to evaluate the accessibility and eligibility of stroke units in Poland...
Wilson's disease-cause of mortality in 164 patients during 1992-2003 observation periodA Członkowska
J Neurol 252:698-703. 2005..There was no difference in mortality rate in patients treated with d-penicillamine or zinc sulphate as initial therapy. The prognosis for survival in the majority of WD patients is favourable, provided that therapy is introduced early...
Monozygotic female twins discordant for phenotype of Wilson's diseaseAnna Członkowska
Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
Mov Disord 24:1066-9. 2009..Her sister remained clinically presymptomatic at diagnosis at the age of 28. We concluded that the phenotypic characteristics of WD are possibly attributable to epigenetic/environmental factors...
The APOE polymorphism and 1-year outcome in ischemic stroke: genotype-gender interactionG Gromadzka
Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, Warsaw, Poland
Acta Neurol Scand 116:392-8. 2007..We aimed to evaluate whether the APOE genotype is related to acute neurological impairments due to ischemic stroke (IS), and to outcomes (up to 1 year) indicated by severe functional disability, dependence in daily living or death...
Factors predicting early stroke fatality in Poland. Preliminary report of the Polish National Stroke RegistryD Ryglewicz
Institute of Psychiatry and Neurology, 1st Department of Neurology, Sobieskiego 1, 02-957 Warsaw, Poland
Neurol Sci 24:301-4. 2003..2% vs. 62.6%), early rehabilitation was delayed (38.3% vs. 73.4%), and secondary prevention treatment was prescribed to fewer patients (antiplatelettherapy 36.4% vs. 77.4%; antithrombotic therapy 4.9% vs. 13%)...
IL1RN intron 2 polymorphism caused by variable number tandem repeats is associated with 1-year outcome in patients with ischaemic strokeG Gromadzka
Institute of Psychiatry and Neurology 2 Medical University, Warsaw, Poland
J Neurol Neurosurg Psychiatry 78:183-6. 2007..In humans, IL1ra is encoded by the IL1RN gene located on chromosome 2...
Intravenous recombinant tissue plasminogen activator for acute stroke in Poland: an analysis based on the Safe Implementation of Thrombolysis in Stroke (SITS) RegistryA Kobayashi
2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
Acta Neurol Scand 122:229-36. 2010..The aim of this study is to compare the safety and efficacy of thrombolysis in the Polish SITS-ISTR stroke patient population with patients registered in SITS-MOST...
A prospective study of the financial costs of multiple sclerosis at different stages of the diseaseE Orlewska
Department of Clinical and Experimental Pharmacology, Medical University of Warsaw, Warsaw, Poland
Eur J Neurol 12:31-9. 2005..This study confirms that MS represents a high economic burden, with indirect costs greatly exceeding direct costs. As costs increase with disease progression, treatment efforts should focus on patients in the early stages of MS...
Do silent infarcts modify the effect of thrombolysis for stroke?A Kobayashi
2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
Acta Neurol Scand 127:227-32. 2013..Our aim was to identify the prevalence of SBI in acute ischaemic stroke patients undergoing routine intravenous thrombolysis and evaluate the association between their presence on pretreatment computed tomography (CT) and outcome...
Factor V Leiden, prothrombin gene G20210A variant, and methylenetetrahydrofolate reductase C677T genotype in young adults with ischemic strokeS Lopaciuk
Institute of Hematology and Blood Transfusion, Warsaw, Poland
Clin Appl Thromb Hemost 7:346-50. 2001..In conclusion, our results indicate that FV Leiden mutation, prothrombin G20210A genotype, and homozygosity for the C677T mutation in the MTHFR gene are not associated with an increased risk for ischemic stroke in young adults...
Sonographic detection of basal ganglia lesions in asymptomatic and symptomatic Wilson diseaseU Walter
Department of Neurology, University of Rostock, Rostock, Germany
Neurology 64:1726-32. 2005..To investigate whether transcranial brain parenchyma sonography (TCS) detects basal ganglia abnormalities in asymptomatic and symptomatic patients with Wilson disease (WD) and whether findings correlate with disease severity...
Relative effects of statin therapy on stroke and cardiovascular events in men and women: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) StudyLarry B Goldstein
Duke University Medical Center, Durham, NC 27710, USA
Stroke 39:2444-8. 2008..9 years of follow-up. The purpose of this secondary analysis was to determine whether men and women similarly benefited from randomization to statin treatment...
Variation in the management of acute physiological parameters after ischaemic stroke: a European perspectiveA Bhalla
Department of Public Health Sciences, Guy s, King s and St Thomas School of Medicine, London, UK
Eur J Neurol 10:25-33. 2003..Further research is required to link variation in acute care with stroke outcome, to identify which interventions appear to be the most effective...
Increase of matrix metalloproteinase-9 in peripheral blood of multiple sclerosis patients treated with high doses of methylprednisoloneD Mirowska
Section of Neurology, Max-Planck-Institute of Psychiatry, Kraepelinstrasse 2-10, D-80804 Munich, Germany
J Neuroimmunol 146:171-5. 2004..No effect was noted on TIMP-1 and MMP-2 levels. The short-lived increase of MMP-9 plasma levels may be at least in part due to an activation and an increase of granulocytes and monocytes by methylprednisolone...
Alemtuzumab vs. interferon beta-1a in early multiple sclerosisAlasdair J Coles
N Engl J Med 359:1786-801. 2008..The study was not powered to identify uncommon adverse events. (ClinicalTrials.gov number, NCT00050778.)..
Predicting outcome in hyper-acute stroke: validation of a prognostic model in the Third International Stroke Trial (IST3)Steff C Lewis
J Neurol Neurosurg Psychiatry 79:397-400. 2008..The SSV model comprising easily collected variables can therefore be used to stratify patients in hyper-acute stroke trials, but probably is not accurate enough for decision-making in individual patients...
Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic strokeWerner Hacke
Department of Neurology, Universitat Heidelberg, Heidelberg, Germany
N Engl J Med 359:1317-29. 2008..We tested the efficacy and safety of alteplase administered between 3 and 4.5 hours after the onset of a stroke...
Three novel mutations (P760L, L1305P, Q1351Stop) causing Wilson diseaseJ Genschel
, Med. Klinik m.S. Gastroenterologie, Hepatologie und Endokrinologie, Berlin, Germany
Hum Mutat 17:156. 2001
